Tidsskrift for Den Norske Laegeforening最新文献

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-12 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.25.0298

Ragnhild Ørstavik

引用次数: 0

A man in his fifties with lymphoma, vomiting and diarrhoea. 一个五十多岁的男人，患有淋巴瘤，呕吐和腹泻。

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-12 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.24.0605

Jakob Lillemoen Drivenes, Anders Lillemoen Drivenes, Randi Haukaas Bjerkreim, Istvan Pregun, Tor Jacob Eide, Otto Emil Nyquist

{"title":"A man in his fifties with lymphoma, vomiting and diarrhoea.","authors":"Jakob Lillemoen Drivenes, Anders Lillemoen Drivenes, Randi Haukaas Bjerkreim, Istvan Pregun, Tor Jacob Eide, Otto Emil Nyquist","doi":"10.4045/tidsskr.24.0605","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0605","url":null,"abstract":"Background: Diagnosing immunosuppressed patients who present with fever and gastrointestinal symptoms can be particularly challenging for clinicians.Case presentation: We report the case of a man in his fifties who developed severe enterocolitis, immunosuppression and protein loss following treatment with rituximab and bendamustine. His medical history included recurrent iridocyclitis and small lymphocytic lymphoma, with subsequent identification of necrobiotic xanthogranuloma, prompting the initiation of chemoimmunotherapy. The patient initially presented with fever, vomiting and diarrhoea. Despite receiving appropriate medical care, he experienced recurrent infections and significant gastrointestinal distress, necessitating an extended hospital stay that involved interdisciplinary collaboration. Initial investigations indicated cytomegalovirus (CMV) reactivation, which was initially misinterpreted as CMV colitis. However, further biopsies revealed no classic CMV lesions, and comprehensive gastroenterological and microbiological evaluations ruled out infectious causes. This led to a diagnosis of rituximab-induced enterocolitis, a rare adverse effect of the treatment, confirmed by re-examination of the biopsies. Despite attempts to manage the condition with corticosteroids and TNF inhibitors, the patient ultimately succumbed to complications, including severe infections and renal failure.Interpretation: This case underscores the critical need to recognise rituximab-induced enterocolitis, especially in patients presenting with unexplained gastrointestinal symptoms during therapy. Timely diagnosis and intervention may improve patient outcomes, highlighting the necessity for vigilant monitoring of such patients.","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 6","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of psychotropic medications in the specialist health service for mental health care and substance use disorders in 2012-23. 2012-23年精神卫生保健和物质使用障碍专科保健服务中精神药物的使用情况。

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-12 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.24.0531

Liv Marit Seljeflot, Hege Salvesen Blix, Yvonne Andersson, Torfinn Hynnekleiv

{"title":"Use of psychotropic medications in the specialist health service for mental health care and substance use disorders in 2012-23.","authors":"Liv Marit Seljeflot, Hege Salvesen Blix, Yvonne Andersson, Torfinn Hynnekleiv","doi":"10.4045/tidsskr.24.0531","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0531","url":null,"abstract":"Background: Data on the use of psychotropic medications in specialist mental health services and interdisciplinary specialised treatment for substance use disorders (SUDs) are useful both as cross-sectional indicators and as time series data for monitoring trends. The figures can help form a basis for evaluating rational use of medications in hospitals.Material and method: Purchasing data for anxiolytics, antidepressants, mood stabilisers and antipsychotics from the Hospital Pharmacies Drug Statistics for the period 2012-23 were used. The data are sourced from sales to specialist mental health clinics and for SUD treatment. Defined daily doses and the number of defined daily doses per 100 bed-days were used as units of measurement.Results: Use of anxiolytics increased by 127 % from 2012 to 2023, while decreasing by 24 % for antidepressants. The use of mood stabilisers and lithium decreased by 26 % and 16 %, respectively. Total use of antipsychotics increased by 29 %, while rising by 79 % for depot injections.Interpretation: Significant changes in medication use were observed during the reference period. Further studies are needed to identify the causes and effects of the changed prescribing patterns.","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 6","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why is the use of antipsychotics increasing? 为什么抗精神病药物的使用在增加？

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-12 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.25.0259

Jeanette Bjørke

引用次数: 0

Tillitsreform er nødvendig.

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-12 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.25.0145

Tobias Solli Iveland

引用次数: 0

Florafikseren. Florafikseren。

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-08 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.25.0213

Martin Hotvedt

引用次数: 0

Self-management of INR - a focus group study. INR的自我管理-焦点小组研究。

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-07 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.24.0336

Andrea Elisabeth Dahle-Andersen, Åshild Lunde, Marit Holm Sølsnes, Una Ørvim Sølvik

{"title":"Self-management of INR - a focus group study.","authors":"Andrea Elisabeth Dahle-Andersen, Åshild Lunde, Marit Holm Sølsnes, Una Ørvim Sølvik","doi":"10.4045/tidsskr.24.0336","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0336","url":null,"abstract":"Background: Warfarin is a medication used in conditions with an increased risk of blood clots. Due to the potential for serious side effects, treatment must be closely monitored by measuring the International Normalised Ratio (INR). In some health trusts, Noklus (Norwegian Organization for Quality Improvement of Laboratory Examinations) offers training for patients in self-management of INR. The aim of this study was to explore Norwegian patients' experiences with self-management of INR and their motivations.Material and method: In 2022, three focus group interviews were conducted at Nordland Hospital in Bodø, with a total of 16 individuals who performed self-management of INR. The interviews were audio-recorded, transcribed and analysed using systematic text condensation.Results: Participants reported improved self-esteem and a sense of freedom after starting self-management of INR. Some expressed initial concerns about the increased responsibility for their own health, but they gradually developed a more relaxed attitude towards self-management. They also experienced reduced stress levels and gained increased knowledge about their own bodies. The training course enhanced participants' knowledge and confidence.Interpretation: The study indicates that self-management of INR simplifies the daily life of patients and can have a positive impact on their quality of life.","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 6","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-led treatment with GP support. 患者主导的治疗与全科医生的支持。

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-07 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.25.0263

Bente Prytz Mjølstad

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Post-bariatric hypoglycaemia. Post-bariatric低血糖。

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-06 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.24.0396

Stephen Hewitt, Dag Hofsø, Elisabeth Qvigstad, Tore Julsrud Berg, Monica Chahal-Kummen, Jon Kristinsson, Tom Mala

引用次数: 0

Hypertensjonsbehandling i lys av nye internasjonale retningslinjer.

IF 1.2

Tidsskrift for Den Norske Laegeforening Pub Date : 2025-05-06 Print Date: 2025-05-13 DOI: 10.4045/tidsskr.25.0169

Sverre E Kjeldsen, Bjørn Gjelsvik, Tor Ole Klemsdal

引用次数: 0