Tissue antigens最新文献_第7页

HLA-D typing by homozygous typing cells. A statistical analysis of experimental and biological variation. 纯合子分型细胞的HLA-D分型。对实验和生物变异的统计分析。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1977.TB01123.X

E. B. Jensen, T. Kristensen, F. Jørgensen, L. Lamm

引用次数: 7

Psoriasis, sacro-iliitis and peripheral arthritis occurring in patients with the same HLA haplotype. A preliminary family report and a hypothetical explanation of the interaction between MHS products. 银屑病、骶髂炎和周围性关节炎发生在具有相同HLA单倍型的患者中。初步的家庭报告和MHS产品之间相互作用的假设解释。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1976.TB00576.X

J. Marcusson, A. Elman, E. Möller, N. Thyresson

{"title":"Psoriasis, sacro-iliitis and peripheral arthritis occurring in patients with the same HLA haplotype. A preliminary family report and a hypothetical explanation of the interaction between MHS products.","authors":"J. Marcusson, A. Elman, E. Möller, N. Thyresson","doi":"10.1111/J.1399-0039.1976.TB00576.X","DOIUrl":"https://doi.org/10.1111/J.1399-0039.1976.TB00576.X","url":null,"abstract":"The present family investigation has shown that genes within the MHS are mainly responsible for the development of psoriasis or psoriasis-associated arthritic lesions (peripheral arthritis and sacroiliitis). We have hypothetically discussed the possibility that multiple genes, all located within the MHS, act in concert to increase the risk of developing disease to very high levels. This implies that at least two MHS linked genes act in complementary fashion for the development of disease, these genes seem to be able to operate both in the cis and in the trans position. One of these genes would be situated in the chromosomal portion of the MHS which carries the HLA-D locus. Families with a high incidence of disease would show inheritance according to the cis position of genes, when it can be shown that most of the carriers of the specific disease-associated haplotype are affected by disease, whereas in other families, complementarity between two distinct HLA haplotypes with genes acting in the trans position would result in disease.","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"8 2 1","pages":"131-8"},"PeriodicalIF":0.0,"publicationDate":"2008-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1399-0039.1976.TB00576.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62840322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

DR2 short antigen in Japanese. A strong association with Bw67 and TB23. 日文DR2短抗原。与Bw67和TB23密切相关。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1986.TB01525.X

K. Matsuki, S. Watanabe, Y. Nanzai, M. Nakatate, T. Juji

引用次数: 4

Human histocompatibility testing by T cell-mediated lympholysis: a European standard CML technique. Report from the European CML study group on the Third European CML workshop. Centre d'immunologie INSERM-CNRS. Marseille, December 1979. 通过T细胞介导的淋巴溶解进行人组织相容性测试:欧洲标准CML技术。欧洲CML研究组关于第三届欧洲CML讲习班的报告。INSERM-CNRS免疫学中心。马赛，1979年12月。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1980.TB00316.X

T. Kristensen

引用次数: 35

HL-A antigens in Japanese Patients with Graves' disease. 日本Graves病患者的HL-A抗原

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1975.TB00654.X

F. Grumet, Rose Payne, Junji Konishi, Toru Morr, J. P. Kriss

{"title":"HL-A antigens in Japanese Patients with Graves' disease.","authors":"F. Grumet, Rose Payne, Junji Konishi, Toru Morr, J. P. Kriss","doi":"10.1111/J.1399-0039.1975.TB00654.X","DOIUrl":"https://doi.org/10.1111/J.1399-0039.1975.TB00654.X","url":null,"abstract":"A group of Japanese were investigated for evidence of an association between Graves' disease and HL-A. Forty-four patients with the disease and 83 normal, unrelated random Japanese and Japanese-American controls were selected for study. The frequency of the W5 antigen among patients (57%) was significantly (P less than .0001) greater than among controls (20%). Of the 34 patients with abnormally elevated serum levels of anti-(thyroid) microsomal (anti-M) auto-antibodies, 56% had the W5 antigen. In contrast, of 48 control individuals tested for anti-M, only seven were seropositive and none (0%) of the seven had the W5 antigen. As expected the HL-A8 antigen was absent from this non-Caucasian population. These data demonstrate that the W5 antigen in Japanese, analogous to the HL-A8 antigen in Caucasians, is associated with Graves' disease but not with anti-M seropositivity in controls. The occurrence of different HL-A antigens in association with the same disease in different ethnic groups requires that the use of a major histocompatibility system antigen as a disease susceptibility marker must be confirmed for each ethnic group under study.","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"6 5 1","pages":"347-52"},"PeriodicalIF":0.0,"publicationDate":"2008-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1399-0039.1975.TB00654.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62840141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 55

A new homozygous typing cell with HLA-D"H" (DB6) specificity. Evidence that the DN-1 monoclonal antibody 9w925 is specific for the HLA-D"H" determinant. 一种新的HLA-D“H”(DB6)特异性纯合子分型细胞。证明DN-1单克隆抗体9w925对HLA-D“H”决定因子具有特异性。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1986.TB01534.X

B. Jakobsen, P. Platz, L. Ryder, A. Svejgaard

{"title":"A new homozygous typing cell with HLA-D\"H\" (DB6) specificity. Evidence that the DN-1 monoclonal antibody 9w925 is specific for the HLA-D\"H\" determinant.","authors":"B. Jakobsen, P. Platz, L. Ryder, A. Svejgaard","doi":"10.1111/J.1399-0039.1986.TB01534.X","DOIUrl":"https://doi.org/10.1111/J.1399-0039.1986.TB01534.X","url":null,"abstract":"A new homozygous typing cell (HTC), SK is described. Mixed leukocyte culture (MLC) showed that SK is homozygous for HLA-D\"H\" (DB6) defined by the HTC, Herluf, and that the HLA-D typing results obtained by Herluf and SK are highly significantly correlated (Kendall's R = 0.46, p = 2.5 X 10(-5)). Both Herluf and SK are also homozygous for a new class II determinant, DN-1, defined by the monoclonal anti-B-lymphocyte antibody, 9w925, developed by Aizawa. The corresponding DN-1 antigen was present in 2.2% of 136 random, unrelated Danes and in all of six unrelated HLA-D\"H\" positive but in none of 20 HLA-D\"H\" negative individuals. Thus, there is an absolute and highly significant (p = 4 X 10(-6)) association between the cellularly defined HLA-D\"H\" determinant and the serologically defined DN-1 antigen, which strongly suggests that HLA-D\"H\" can now be detected serologically. DN-1 may be identical to DRw12 which is, however, poorly defined. The HTC-donor SK was immunized by pregnancy, and her serum contains anti-HLA-B7, which can easily be absorbed, and anti-B-lymphocyte antibodies which reacted with cells from 87.7% of 536 unrelated Danes. The reaction pattern of this serum is negatively associated with DR3, w6, and w8. This serum may define a new broad, cross-reacting antigen belonging to the same group as DRw52 and DRw53 or DQw1-w3, but it is clearly different from each of these antigens.","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"27 5 1","pages":"285-90"},"PeriodicalIF":0.0,"publicationDate":"2008-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1399-0039.1986.TB01534.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62843353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

HLA antigens and glomerulonephritis. HLA抗原与肾小球肾炎。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1975.TB00657.X

H. Jensen, L. Ryder, L. Nielsen, E. Clausen, F. Jørgensen, H. Jorgensen

引用次数: 6

Lack of association of HLA with thyroid cancer. An effect of iodine sufficiency and safe environment? HLA与甲状腺癌缺乏相关性。缺碘与环境安全的关系?

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1986.TB00499.X

B. Larsen, C. Thompson, A. Kwan, N. Farid

引用次数: 14

HLA genetic determinants in familial MS. A study from the Grampian region of Scotland. 苏格兰格兰平原地区家族性多发性硬化症的HLA遗传决定因素研究。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1987.TB01542.X

D. Francis, J. Batchelor, W. Mcdonald, I. Dodi, S. Hing, J. Hern, A. Downie

{"title":"HLA genetic determinants in familial MS. A study from the Grampian region of Scotland.","authors":"D. Francis, J. Batchelor, W. Mcdonald, I. Dodi, S. Hing, J. Hern, A. Downie","doi":"10.1111/J.1399-0039.1987.TB01542.X","DOIUrl":"https://doi.org/10.1111/J.1399-0039.1987.TB01542.X","url":null,"abstract":"Fourteen multiplex MS families, 9 single-case MS families and 11 normal families from the Grampian region of North-East Scotland were studied. The prevalence rate of MS for individuals in multiplex families was calculated at 809/100,000; 4.5 times the prevalence rate for the general population in this region. The distribution of shared haplotypes in 12 affected and 19 unaffected sib-pair comparisons did not differ significantly from that expected by chance. Furthermore there was no evidence that homozygosity of a particular HLA gene was required for increased susceptibility to the disease. HLA-B7, C4A3, C4B1, BfS, HLA-DR2, HLA-DQw1 was the commonest haplotype accounting for 18.9% and 24.2% of parental haplotypes from multiplex and single-case families, respectively, compared with 2.3% of parental haplotypes from control families (p less than 0.05 and p less than 0.01, respectively). No significant differences were observed in the frequencies of complement gene polymorphisms (Factor B and C4). The data suggests that a MS susceptibility gene exists, in the HLA complex, and is in closest linkage disequilibrium with the HLA-D region; although other factors, environmental and/or independent genetic loci, may have an important influence.","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"29 1 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2008-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1399-0039.1987.TB01542.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62842904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Cellular cytotoxicity against canine endothelial cells. Analysis of determinants recognized by CTL. 犬内皮细胞的细胞毒性。CTL识别的决定因素分析。

Tissue antigens Pub Date : 2008-12-11 DOI: 10.1111/J.1399-0039.1983.TB00379.X

G. Groenewegen, W. Buurman, C. J. van der Linden, G. Jeunhomme, G. Kootstra

引用次数: 9