{"title":"PRMT Inhibitors","authors":"M. V. van Haren, N. Martin","doi":"10.1007/7355_2019_73","DOIUrl":"https://doi.org/10.1007/7355_2019_73","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73756328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evolution of HCV NS4B Inhibitors","authors":"G. Manfroni, R. Cannalire","doi":"10.1007/7355_2018_46","DOIUrl":"https://doi.org/10.1007/7355_2018_46","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79022259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discovery of Boceprevir, a Ketoamide-Derived HCV NS3 Protease Inhibitor, for Treatment of Genotype 1 Infections","authors":"S. Venkatraman","doi":"10.1007/7355_2018_40","DOIUrl":"https://doi.org/10.1007/7355_2018_40","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79427306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evolution of HCV NS5B Nucleoside and Nucleotide Inhibitors","authors":"A. Cho","doi":"10.1007/7355_2018_36","DOIUrl":"https://doi.org/10.1007/7355_2018_36","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82678136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Clinical Development of Ledipasvir/Sofosbuvir (LDV/SOF, Harvoni®)","authors":"A. Osinusi, J. McHutchison","doi":"10.1007/7355_2018_48","DOIUrl":"https://doi.org/10.1007/7355_2018_48","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89635799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chemical Compounds Targeting DNA Methylation and Hydroxymethylation","authors":"R. Belle, A. Kawamura, P. Arimondo","doi":"10.1007/7355_2019_76","DOIUrl":"https://doi.org/10.1007/7355_2019_76","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87116616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. McDaniel, Y. Ku, Ying Sun, Hui-ju Chen, Jason P. Shanley, T. Middleton, Y. Or, D. Kempf
{"title":"The Discovery and Development of HCV NS3 Protease Inhibitor Paritaprevir","authors":"K. McDaniel, Y. Ku, Ying Sun, Hui-ju Chen, Jason P. Shanley, T. Middleton, Y. Or, D. Kempf","doi":"10.1007/7355_2018_42","DOIUrl":"https://doi.org/10.1007/7355_2018_42","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87387448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structure-Based Design of Epigenetic Inhibitors","authors":"D. Robaa, Jelena Melesina, C. Luise, W. Sippl","doi":"10.1007/7355_2019_80","DOIUrl":"https://doi.org/10.1007/7355_2019_80","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85038791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inhibitors of JmjC-Containing Histone Demethylases","authors":"M. Wright, P. Brennan, A. Kawamura","doi":"10.1007/7355_2019_75","DOIUrl":"https://doi.org/10.1007/7355_2019_75","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87754019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}