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Topics in Medicinal Chemistry最新文献

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The Invention of Grazoprevir: An HCV NS3/4a Protease Inhibitor 一种HCV NS3/4a蛋白酶抑制剂Grazoprevir的发明
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2018_41
J. Mccauley, M. Rudd
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引用次数: 2
HCV NS5A as an Antiviral Therapeutic Target: From Validation to the Discovery and Development of Ombitasvir and Pibrentasvir as Components of IFN-Sparing HCV Curative Treatments HCV NS5A作为抗病毒治疗靶点:从验证到Ombitasvir和Pibrentasvir作为节省ifn的HCV治疗成分的发现和发展
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2018_50
R. Wagner, D. DeGoey, J. Randolph, C. KruegerAllan, M. Matulenko, W. Kati
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引用次数: 1
Perspectives on HCV Cure HCV治疗的前景
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2019_65
M. Sofia
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引用次数: 0
The Clinical Development of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX, Vosevi®) Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX, Vosevi®)的临床研究进展
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2018_49
L. Stamm, J. McHutchison
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引用次数: 1
Applications of Fluorescent Protein-Based Sensors in Bioimaging 荧光蛋白传感器在生物成像中的应用
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2019_90
Uday K Sukumar, A. Natarajan, T. Massoud, R. Paulmurugan
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引用次数: 3
Cure and Control: What Will It Take to Eliminate HCV? 治疗和控制:怎样才能消除丙型肝炎?
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2018_56
M. Martinello, B. Hajarizadeh, J. Grebely, G. Matthews, G. Dore
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引用次数: 1
From B to Non-B to C: The Hepatitis C Virus in Historical Perspective 从B型到非B型到C型:历史视角下的丙型肝炎病毒
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2018_33
H. Alter
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引用次数: 1
Development and Marketing of INCIVEK (Telaprevir; VX-950): A First-Generation HCV Protease Inhibitor, in Combination with PEGylated Interferon and Ribavirin INCIVEK (Telaprevir)的开发和销售;VX-950):第一代HCV蛋白酶抑制剂，与聚乙二醇化干扰素和利巴韦林联合使用
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2018_57
A. Kwong, R. Perni, C. Graham
{"title":"Development and Marketing of INCIVEK (Telaprevir; VX-950): A First-Generation HCV Protease Inhibitor, in Combination with PEGylated Interferon and Ribavirin","authors":"A. Kwong, R. Perni, C. Graham","doi":"10.1007/7355_2018_57","DOIUrl":"https://doi.org/10.1007/7355_2018_57","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"613 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80428388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors 组蛋白乙酰转移酶:从生物学意义到最相关的抑制剂
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2019_71
D. Trisciuoglio, D. Rotili
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引用次数: 2
Sirtuin Inhibitors and Activators Sirtuin抑制剂和激活剂
Topics in Medicinal Chemistry Pub Date : 2019-01-01 DOI: 10.1007/7355_2019_70
Minna Rahnasto-Rilla, Jonna Tyni, M. Lahtela-Kakkonen
{"title":"Sirtuin Inhibitors and Activators","authors":"Minna Rahnasto-Rilla, Jonna Tyni, M. Lahtela-Kakkonen","doi":"10.1007/7355_2019_70","DOIUrl":"https://doi.org/10.1007/7355_2019_70","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"344 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79614354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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