Thomas Starch-Jensen, Daniel Deluiz, Niels Henrik Bruun, Eduardo Muniz Barretto Tinoco
{"title":"Maxillary Sinus Floor Augmentation with Autogenous Bone Graft Alone Compared with Alternate Grafting Materials: a Systematic Review and Meta-Analysis Focusing on Histomorphometric Outcome.","authors":"Thomas Starch-Jensen, Daniel Deluiz, Niels Henrik Bruun, Eduardo Muniz Barretto Tinoco","doi":"10.5037/jomr.2020.11302","DOIUrl":"https://doi.org/10.5037/jomr.2020.11302","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of present systematic review was to test the hypothesis of no difference in histomorphometric outcome after maxillary sinus floor augmentation with autogenous bone graft alone compared with alternate grafting materials applying the lateral window technique.</p><p><strong>Material and methods: </strong>MEDLINE (PubMed), Embase and Cochrane library search in combination with hand-search of relevant journals were conducted. Human studies published in English until the 25<sup>th</sup> of March, 2020 were included. Histomorphometric outcomes were evaluated by descriptive statistics and meta-analysis including 95% confidence interval (CI).</p><p><strong>Results: </strong>Electronic search and hand-searching resulted in 1902 entries. Sixteen randomized controlled trials with unclear risk of bias fulfilled the inclusion criteria. Descriptive statistics showed comparable or improved histomorphometric outcomes with autogenous bone graft. Meta-analysis revealed a mean difference of -7.1% (CI = -11.0 to -3.2) indicating a significant higher amount of bone after maxillary sinus floor augmentation with autogenous bone graft compared with alternate grafting materials. Subgroup analysis demonstrated a non-significantly differences of -3.7% (CI = -10.9 to 3.4), -11.5% (CI = -25.9 to 2.8), 2.2% (CI = -16.9 to 21.3), and -4.6% (CI = -14.4 to 5.2), when autogenous bone graft was compared with allogeneic bone graft, xenograft, composite grafting materials involving xenograft or synthetic biomaterial mixed with autogenous bone graft, respectively.</p><p><strong>Conclusions: </strong>Maxillary sinus floor augmentation with autogenous bone graft seems to facilitate improved histomorphometric outcomes compared with alternate grafting materials. However, the included studies were characterised by an unclear risk of bias and various methodological confounding factors. Hence, the conclusions drawn from the results of present study should be interpreted with caution.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 3","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/c4/jomr-11-e2.PMC7644272.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38665990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peculiarities of Dental Treatment among Paediatric Oncological Patients: a Case Report.","authors":"Egle Aida Bendoraitiene, Vilija Andruskeviciene, Gabriele Kscenaviciute, Evelina Srebaliene, Ieva Maciulaityte","doi":"10.5037/jomr.2020.11305","DOIUrl":"https://doi.org/10.5037/jomr.2020.11305","url":null,"abstract":"<p><strong>Objectives: </strong>According to the National Cancer Institute of Lithuania, cancer is diagnosed for almost 100 children each year. Oncological patients suffer from complications during and after treatment. Radiation therapy also affects dental hard tissues. Many oncological patients lose motivation to take care of their oral hygiene because they are focused on cancer diagnosis. This case report discusses prevention and dental treatment severity after radiation therapy treatment.</p><p><strong>Material and methods: </strong>A 9-year-old boy with cancer diagnosis visited a dentist in 2017. The patient was complaining about poor aesthetic quality of the teeth, but there were no complaints about teeth sensitivity or pain. Different stages of active caries, poor oral hygiene, visible abundant plaque, swollen, red and bleeding gums were observed during appointment. A motivational interview explaining the importance of oral hygiene was conducted. Non-surgical caries treatment was prescribed during the first visit. Restorative treatment was performed after 1 month.</p><p><strong>Results: </strong>The motivational interview explaining the importance of oral hygiene was conducted during every appointment per 3-year period. Unfortunately, oral hygiene is still poor due to the lack of motivation. Active-cavitated caries lesions were restored with glass ionomer cement and composite resin. The aesthetics of teeth was improved.</p><p><strong>Conclusions: </strong>Oncological and recovered patients after radiation therapy should be assigned to a high risk of caries. These patients should be treated individually by the algorithm. Psychological or psychotherapeutic assistance is necessary for patients due to motivation for treatment and oral care.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 3","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/52/jomr-11-e5.PMC7644269.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38666440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bart A J A van Oirschot, John A Jansen, Cindy J J M van de Ven, Edwin J W Geven, Jan A Gossen
{"title":"Evaluation of Collagen Membranes Coated with Testosterone and Alendronate to Improve Guided Bone Regeneration in Mandibular Bone Defects in Minipigs.","authors":"Bart A J A van Oirschot, John A Jansen, Cindy J J M van de Ven, Edwin J W Geven, Jan A Gossen","doi":"10.5037/jomr.2020.11304","DOIUrl":"https://doi.org/10.5037/jomr.2020.11304","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of the present <i>in vivo</i> study was to evaluate whether pericard collagen membranes coated with ancillary amounts of testosterone and alendronate in a poly-lactic glycolic acid (PLGA) carrier as compared to uncoated membranes will improve early bone regeneration.</p><p><strong>Material and methods: </strong>In each of 16 minipigs, four standardized mandibular intraosseous defects were made bilaterally. The defects were filled with Bio-Oss<sup>®</sup> granules and covered with a non-coated or coated membrane. Membranes were spray-coated with 4 layers of PLGA containing testosterone and alendronate resulting in 20, 50 or 125 μg/cm<sup>2</sup> of testosterone and 20 µg/cm<sup>2</sup> alendronate (F20, F50, F125). Non-coated membranes served as controls (F0). Animals were sacrificed at 6 and 12 weeks after treatment. Qualitative and quantitative histological evaluations of bone regeneration were performed. Differences between groups were assessed by paired Student's t-test.</p><p><strong>Results: </strong>Light microscopical analysis showed new bone formation that was in close contact with the Bio-Oss<sup>®</sup> surface without an intervening non-mineralized tissue layer. Histomorphometric analysis of newly formed bone showed a significant 20% increase in area in the F125 coated membrane treated defects (40 [SD 10]%) compared to the F0 treated defects after 6 weeks (33 [SD 10]%, P = 0.013). At week 12, the total percentage of new bone was increased compared to week 6, but no increase in newly formed bone compared to F0 was observed.</p><p><strong>Conclusions: </strong>The data from this <i>in vivo</i> study indicate that F125 collagen membranes coated with testosterone and alendronate resulted in superior bone formation (+24%) when normalized to control sites using uncoated membranes.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 3","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/6b/jomr-11-e4.PMC7644271.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38663408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immediate Implant Placement in Non-Infected Sockets versus Infected Sockets: a Systematic Review and Meta-Analysis.","authors":"Aza Saijeva, Gintaras Juodzbalys","doi":"10.5037/jomr.2020.11201","DOIUrl":"https://doi.org/10.5037/jomr.2020.11201","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this systematic review is to compare immediate implant placement in infected extraction sockets with non-infected extraction sockets in terms of implant survival and function.</p><p><strong>Material and methods: </strong>An electronic search was conducted in PubMed, ScienceDirect, ISI Web of Knowledge and Google Scholar between January 2010 and February 2020. Studies evaluating implant survival rate and main clinical parameters were included for a qualitative and quantitative analysis.</p><p><strong>Results: </strong>In total, nine studies were included and a pool of 2281 sockets were analysed. Compared with the non-infected group, the infected group showed no significant differences in implant survival rates (risk ratio [RR] = 0.99; 95% confidence interval [CI] = 0.98 to 1; P = 0.08). No significant statistical differences were found in marginal bone level (mean difference [MD] = -0.03; 95% CI = -0.1 to 0.04; P = 0.41), marginal gingival level (MD = -0.07; 95% CI = -0.17 to 0.04; P = 0.23), probing depth (MD = 0.06; 95% CI = -0.24 to 0.36; P = 0.7), modified bleeding index (MD = -0.00162196; 95% CI = -0.09 to 0.09; P = 0.97) and slight but significant changes were seen in width of keratinized gingiva (MD = 0.25; 95% CI = -0.3 to 0.8; P = 0.38) between the groups at the latest follow-up.</p><p><strong>Conclusions: </strong>There were no significant difference in implant survival rates, marginal bone level, marginal gingival level, modified bleeding index and probing depth between infected sockets and non-infected sockets. However, slight but significant changes were seen in width of keratinized gingiva favouring the non-infected group.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 2","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a3/6a/jomr-11-e1.PMC7393932.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38244613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Efficacy of Soprolife<sup>®</sup> in Detecting <i>in Vitro</i> Remineralization of Early Caries Lesions.","authors":"Mona Zeitouny, Frédéric Cuisinier, Hervé Tassery, Hussein Fayyad-Kazan","doi":"10.5037/jomr.2020.11206","DOIUrl":"https://doi.org/10.5037/jomr.2020.11206","url":null,"abstract":"<p><strong>Objectives: </strong>This randomized controlled <i>in vitro</i> 4-arm trial study aimed to evaluate the efficacy of SoproLife<sup>®</sup> in detecting and quantifying <i>in vitro</i> remineralization with early caries lesions.</p><p><strong>Material and methods: </strong>Sixty human teeth were randomly assigned into four equal groups. Groups 1 and 2 were prophylactically cleaned; groups 3 and 4 were not. Group 1 received treatment with MI Varnish<sup>®</sup> and Recaldent™ for 30 days. Group 2 was treated similarly, but without MI Varnish<sup>®</sup>. Group 3 was treated as 1 and Group 4 as 2. Mineral composition was obtained using scanning electron microscopy with energy dispersive X-ray analysis SoproLife<sup>®</sup> camera images on the occlusal surfaces were analysed for grey value distribution and difference in mean intensity values (DI). Paired t-test and Mann-Whitney-U test were used for intragroup comparison between baseline and T1. Kruskal-Wallis followed by Mann-Whitney-U tests were used for inter-group comparisons at T1.</p><p><strong>Results: </strong>All groups exhibited a significant increase in calcium content and calcium-to-phosphorus ratio (P < 0.05), except Group 4 (Group 1 showed the greatest increase, then Groups 3 and 2). Grey intensity values decreased in all groups (P < 0.05). Group 1 showed the greatest change in DI (16.82 [SD 12.07]), followed by Group 3 (12.46 [SD 9.41]), 2 (10.45 [SD 7.76]), and 4 (6.46 [SD 6.21]). The difference in DI was different between the compared groups (P = 0.038); Groups 1 and 3 exhibited a greater DI compared with 4 (P < 0.01).</p><p><strong>Conclusions: </strong>Within the limitations of this study, SoproLife<sup>®</sup> is effective for early detection and for longitudinally monitoring the remineralization after Recaldent™ therapy.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 2","pages":"e6"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/9a/jomr-11-e6.PMC7393931.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38243624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jelena Gudac, Kristina Hellén-Halme, Tadas Venskutonis, Algirdas Puisys, Vita Machiulskiene
{"title":"Comparison of Selected Anatomical and Treatment-related Diagnostic Parameters Estimated by Cone-Beam Computed Tomography and Digital Periapical Radiography in Teeth with Apical Periodontitis.","authors":"Jelena Gudac, Kristina Hellén-Halme, Tadas Venskutonis, Algirdas Puisys, Vita Machiulskiene","doi":"10.5037/jomr.2020.11204","DOIUrl":"https://doi.org/10.5037/jomr.2020.11204","url":null,"abstract":"<p><strong>Objectives: </strong>To compare selected anatomical and treatment-related diagnostic parameters estimated by cone-beam computed tomography and by digital periapical radiography in teeth with apical periodontitis, and to evaluate reliability of different examiners in interpretation of images obtained by both methods.</p><p><strong>Material and methods: </strong>Teeth with apical periodontitis were evaluated independently by 2 endodontists and 1 radiologist based on 128 cone-beam computed tomography (CBCT) and 162 digital periapical radiography (DPR) images. Anatomical (size, relation with root, location of periapical radiolucency) and treatment-related (canal obturation length, homogeneity, coronal seal) parameters were assessed. Fleiss kappa reflected inter-observer agreement while intra-examiner agreement was estimated by Cohen's kappa. McNemar and McNemar-Bowker tests served for evaluation of differences between CBCT- and DPR-based estimates.</p><p><strong>Results: </strong>Cohen's kappa ranged from 0.62 to 1 for all examiners. Fleiss kappa values were nearly perfect for majority of parameters. Diagnostic discrepancy between methods was found for size of radiolucency that in 15 - 17% cases was larger, and in 25 - 28% smaller in DPR than in CBCT images. DPR revealed 20% of root canals scored as non-obturated while in CBCT - obturation present. Canal obturation was rated as homogenous by CBCT, while absent or non-homogenous by DPR, in 17 - 23%, and 11 - 14% of cases, respectively. Radiologist detected more root perforations in CBCT than in DPR images.</p><p><strong>Conclusions: </strong>Good intra- and inter-examiner agreement for anatomical and treatment-related diagnostic parameters was achieved using cone-beam computed tomography and digital periapical radiography methods and demonstrated similar diagnostic capability, although variation regarding root perforations and canal obturation quality was observed.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 2","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/80/jomr-11-e4.PMC7393929.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38243622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie Kjærgaard Larsen, Thomas Kofod, Kirsten Duch, Thomas Starch-Jensen
{"title":"Short-term Haematological Parameters Following Surgical Removal of Mandibular Third Molars with Different Doses of Methylprednisolone Compared with Placebo. A Randomized Controlled Trial.","authors":"Marie Kjærgaard Larsen, Thomas Kofod, Kirsten Duch, Thomas Starch-Jensen","doi":"10.5037/jomr.2020.11203","DOIUrl":"https://doi.org/10.5037/jomr.2020.11203","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the influence of a single intraoperative injection of methylprednisolone on short-term haematological parameters following surgical removal of mandibular third molars.</p><p><strong>Material and methods: </strong>Fifty-two patients with indications for surgical removal of bilateral impacted mandibular third molars were included in a randomized, split-mouth and double-blinded study design. Each molar were randomly allocated into one of following four groups: 20 mg methylprednisolone, 30 mg methylprednisolone, 40 mg methylprednisolone and placebo. Peripheral blood samples were obtained before and three days after surgery. Haematological parameters involving haemoglobin, white blood cell count and C-reactive protein (CRP) were evaluated and expressed as mean changes. Level of significance was 0.05. Furthermore, outcomes were correlated for age, sex, smoking and time of surgery.</p><p><strong>Results: </strong>There were no significant differences in postoperative haematological parameters with different doses of methylprednisolone compared with placebo. Peripheral blood samples revealed decreased level of haemoglobin and increased level of leucocytes and CRP in each group. Smokers displayed a significant lower level of haemoglobin and CRP compared with non-smokers (P < 0.05) and level of eosinophils decreased significantly with increasing age (P < 0.05).</p><p><strong>Conclusions: </strong>This study indicates that a single intraoperative injection of methylprednisolone seems not to cause suppression of short-term haematological parameters compared with placebo following surgical removal of mandibular third molars.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 2","pages":"e3"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/75/jomr-11-e3.PMC7393928.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38244617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mona Zeitouny, Hasan Fayyad-Kazan, Herve Tassery, Hussein Fayyad-Kazan
{"title":"<i>In Vitro</i> Influence of Prophylaxis Cleaning on Enamel Remineralization with Casein Phosphopeptide-Amorphous Calcium Phosphate.","authors":"Mona Zeitouny, Hasan Fayyad-Kazan, Herve Tassery, Hussein Fayyad-Kazan","doi":"10.5037/jomr.2020.11104","DOIUrl":"https://doi.org/10.5037/jomr.2020.11104","url":null,"abstract":"<p><strong>Objectives: </strong>This randomized controlled <i>in vitro</i> 4-arm trial study aimed to study the remineralization potential of Recaldent™ and assess the effects of prophylaxis cleaning and MI Varnish<sup>®</sup> on enhancing this remineralization potential.</p><p><strong>Material and methods: </strong>Sixty human teeth were randomly assigned into equal samples (A/B). Sample A was prophylactically cleaned, randomly divided into equal samples (1/2). Sample A1 received treatment with MI Varnish<sup>®</sup> and Recaldent™ for 30 days. Sample A2 was treated similarly but without MI Varnish<sup>®</sup>. Sample B did not receive prophylaxis cleaning and was divided into equal samples (1/2). Sample B1 was treated as A1 and sample B2 as A2. The teeth were examined for mineral composition at baseline, after the interventions (T1), and after prophylaxis cleaning (T2). Study outcomes were mineral content (% weight of carbon [C], phosphorus [P], calcium [Ca], oxygen [O], chlorine [Cl], sodium [Na] and silicon [Si]) and calcium-phosphorus ratio (Ca/P).</p><p><strong>Results: </strong>All groups had similar mineral composition at baseline. At T1, sample B2 exhibited least P, Ca and Ca/P content. Samples A1 and B1 showed higher content of P and Ca, compared to B2 (A1 only exhibited higher Ca/P). Sample A2 exhibited lowest Cl and Na content. At T2, sample A1 exhibited lowest C, P, O and Si content (highest Ca/P). Sample A2 showed least Ca/P, and highest Na content.</p><p><strong>Conclusions: </strong>Teeth treated by Recaldent™ proceeded by prophylaxis cleaning or MI Varnish<sup>®</sup> showed remineralization, especially when receiving both interventions. This superior effect persisted even after a second cleaning. Further trials are necessary to provide conclusive evidence in humans.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 1","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/46/jomr-11-e4.PMC7191381.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37909535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How Successful is Supplemental Intraseptal and Buccal Infiltration Anaesthesia in the Mandibular Molars of Patients Undergoing Root Canal Treatment or Tooth Extraction?","authors":"Giath Gazal, Rayan Bahabri, Albraa B Alolayan, Mahmod Alkayyal, Rahaf Al-Ghamdi, Ruwaa Salamah","doi":"10.5037/jomr.2020.11105","DOIUrl":"https://doi.org/10.5037/jomr.2020.11105","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the success rate of supplemental intraseptal and buccal infiltration anaesthesia in mandibular molars undergoing endodontic therapy/extraction when the inferior alveolar nerve block has failed.</p><p><strong>Material and methods: </strong>A prospective clinical trial including 200 patients undergoing lower molar root canal treatment/teeth extraction was conducted. Only 80 patients of the participants who had profound lower lip anaesthesia after the administration of inferior alveolar nerve block (IANB) were in pain within treatment. Patients experiencing moderate to severe pain upon using elevators, forceps, bur, or endodontic file were randomly allocated to the 2% lidocaine intraseptal injection and 4% articaine buccal infiltration groups. Level of pain was assessed every 2 to 10 min on standard 100 mm visual analogue scales.</p><p><strong>Results: </strong>Overall, 55 (69%) of patients who were given either intraseptal injection of 2% lidocaine or buccal infiltration of 4% articaine had successful anaesthesia of lower molar teeth within 10 min. However, 25 (31%) of participating patients in the buccal infiltration and the intraseptal groups had failed anaesthesia within the study duration (10 min), and they received additional local anaesthetic. IANBs were more painful than buccal and intraseptal injections. However, buccal articaine injections were significantly more comfortable than intraseptal lidocaine injections (P > 0.001).</p><p><strong>Conclusions: </strong>Supplemental intraseptal injection of 2% lidocaine and buccal infiltration of 4% articaine achieved profound pulpal anaesthesia in 69% of patients when the inferior alveolar nerve block failed. Recommendations can be given to dental practitioners to use infiltration of 4% articaine in conjunction with intraseptal injection of 2% lidocaine to anaesthetize the lower molar teeth when inferior alveolar nerve block fails.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 1","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/b3/jomr-11-e5.PMC7191379.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37909532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Starch-Jensen, Daniel Deluiz, Eduardo Muniz Barretto Tinoco
{"title":"Horizontal Alveolar Ridge Augmentation with Allogeneic Bone Block Graft Compared with Autogenous Bone Block Graft: a Systematic Review.","authors":"Thomas Starch-Jensen, Daniel Deluiz, Eduardo Muniz Barretto Tinoco","doi":"10.5037/jomr.2020.11101","DOIUrl":"https://doi.org/10.5037/jomr.2020.11101","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the present systematic review was to test the hypothesis of no difference in implant treatment outcome after horizontal ridge augmentation with allogeneic bone block compared with autogenous bone block.</p><p><strong>Material and methods: </strong>A MEDLINE (PubMed), Embase and Cochrane Library search in combination with a hand-search of relevant journals was conducted including human studies published in English through March 13, 2019. Comparative and non-comparative studies evaluating horizontal ridge augmentation with allogeneic bone block were included. Cochrane risk of bias tool and Newcastle-Ottawa Scale were used to evaluate risk of bias.</p><p><strong>Results: </strong>One comparative study with high quality and 12 non-comparative studies fulfilled the inclusion criteria. Considerable heterogeneity prevented meta-analysis from being performed. The comparative retrospective short-term study demonstrated no significant difference in implant treatment outcome between the two treatment modalities. Non-comparative long-term studies revealed high implant survival, gain in alveolar ridge width and bone regeneration with allogeneic bone block. However, non-comparative studies disclosed high incidence of complications including dehiscence, exposure of allogeneic bone block and partial or total loss of the grafts.</p><p><strong>Conclusions: </strong>There seemed to be no difference in implant treatment outcome after horizontal ridge augmentation with allogeneic bone block compared with autogenous bone block. However, increased risk of complications was frequently reported with allogeneic bone block.</p>","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"11 1","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/3c/jomr-11-e1.PMC7191383.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37909590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}