{"title":"Proceedings: Inhibition of bovine factor VIII and ristocetin plus human factor VIII induced platelet agglutination by small peptides.","authors":"D E Macfarlane","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"582-3"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12414172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of experimental coronary thrombosis upon regional and systemic plasma chromatographic patterns.","authors":"P Chowdhury, C B Moschos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An evaluation of changes in the plasma chromatographic pattern was carried out in dogs with experimental coronary thrombosis. Sequential samples were taken simultaneously from the aorta and coronary sinus over a two, four and twenty-four hour period. In addition to gel-chromatography, immunodiffusion and electrophoresis were also employed to identify the protein components of the elution fractions. The results showed that there was a shift of the normal chromatographic pattern to the left from the control within two hours following thrombotic occlusion of the coronary artery and it was maintained over a twenty-four hour period. The shift to the left was presumably due to the earlier elution of the heavy molecular weight components forming as a result of the thrombotic process. The early appearance of the altered chromatographic pattern constitutes an important advantage worthy of further exploration for possible diagnostic application in the human subject.</p>","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"504-12"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11999837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of different mathematical models for calculating and expressing the results of coagulation test procedures.","authors":"J Kahan, I Norén","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coagulation activity, expressed as percentage of normal and as clotting time ratio, was estimated in 220 specimens from patients on long-term anticoagulant treatment by 3 different coagulation test procedures, i.e. Thrombotest, Simplastin-A and Normotest. The estimates were calculated from the same determinations. The distribution of percentage values showed a fairly pronounced deviation from normality. After logarithmic transformation, the distribution was normalized, the regression lines between Thrombotest and other tests became parallel, and that between PIVKA-insensitive systems was shifted to a 45 degree line. Logarithmic transformation also stabilized the residual variance. These features make percentage values accessible for treatment according to the standard methods of bioassay statistics. Attempts to normalize the distribution of ratio values by various transformations were unsuccessful. Formal analysis of data revealed a variation in the proportionality of ratio values with the level of estimated coagulation defect. This may restrict the usefulness of the ratio approach. Logarithmic transformation partly reduced the discrepancy.</p>","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"522-30"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12373885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter: Accelerated hemostasis in chloroquine-treated rats.","authors":"W F Ward, F I Lipschutz, E W Hahn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"545-7"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12373887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Tranqui, V L Marder, M Suscillon, A Z Budzynski, G Hudry
{"title":"Proceedings: Electron microscopic studies of the molecular shape of fibrinogen molecule.","authors":"L Tranqui, V L Marder, M Suscillon, A Z Budzynski, G Hudry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"571-2"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12375101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings: Duration of the inhibition effect of acetylsalicylic acid on human platelet function.","authors":"G Baele, L Verdonck, A Vermeulen, F Barbier","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"576"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12375113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N van Zandwijk, T F Lenssen, E M Prakke, J van der Meer, A S Groen
{"title":"Proceedings: Leucocytes and platelets in isolated lung perfusion.","authors":"N van Zandwijk, T F Lenssen, E M Prakke, J van der Meer, A S Groen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"579"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12375119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings: Inhibition of ristocetin-induced platelet aggregation (RIPA) by Haemaccel and fibrinogen.","authors":"J Stibbe, E Kirby","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"583"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12375127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings: Comparison of in vivo and in vitro effects of platelet function suppressing drugs.","authors":"M Buchanan, J Hirsh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23068,"journal":{"name":"Thrombosis et diathesis haemorrhagica","volume":"34 2","pages":"552"},"PeriodicalIF":0.0,"publicationDate":"1975-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12375269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}