THE ULUTAS MEDICAL JOURNAL最新文献_第2页

Evaluating the Efficiency of the Ottawa Risk Scale in Assessing Adverse Outcomes in COPD Patients Presenting to the Emergency Department 评估渥太华风险量表在评估急诊科COPD患者不良结局中的有效性

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230822072102

Oya Oruc, Serife Ozdinc, Hulya Sevil

{"title":"Evaluating the Efficiency of the Ottawa Risk Scale in Assessing Adverse Outcomes in COPD Patients Presenting to the Emergency Department","authors":"Oya Oruc, Serife Ozdinc, Hulya Sevil","doi":"10.5455/umj.20230822072102","DOIUrl":"https://doi.org/10.5455/umj.20230822072102","url":null,"abstract":"Introduction: Chronic Obstructive Pulmonary Disease (COPD) exacerbations present significant challenges in emergency care settings. Predictive tools like the Ottawa Risk Scale (ORS) can potentially enhance early patient management. We aimed to assess the reliability and efficiency of the ORS among COPD in emergency departments. Materials and Methods: The study reviewed 75 patients presenting with COPD exacerbations were evaluated using the ORS. The ORS categorized patients into four risk groups: Low, Medium, High, and Very High. Clinical characteristics, blood gas analyses, and imaging results were documented. Results: Clinical symptoms were prevalent across all risk categories, but a significant association was found between smoking history and ORS categorization (p=0.042), oxygen saturation levels (p=0.043), initial PaO2 levels (p=0.013), initial and post-treatment PaCO2 (p=0.008, p=0.003 respectively), and pathological X-ray findings (p=0.005). The mMRC scale showed a correlation with ORS categorization (p=0.0001). The High and Very High-risk groups had higher hospitalization rates and adverse outcomes than Low and Medium risk. Conclusion: The ORS is a promising tool for predicting short-term adverse outcomes in COPD within emergency settings. This study underscores its potential utility in aiding clinical decision-making, guiding interventions, and improving patient outcomes.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"237 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Color Doppler Ultrasonographic Evaluation of the Intrauterine Hepatic and Portal Venous System 彩色多普勒超声对宫内肝脏和门静脉系统的评价

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230901100512

Mehmet Sarica, Resat Kervancioglu

{"title":"Color Doppler Ultrasonographic Evaluation of the Intrauterine Hepatic and Portal Venous System","authors":"Mehmet Sarica, Resat Kervancioglu","doi":"10.5455/umj.20230901100512","DOIUrl":"https://doi.org/10.5455/umj.20230901100512","url":null,"abstract":"Introduction: We aimed to determine the changes, varieties, and differences of the Doppler index of the umbilical, uterine and fetal middle cerebral artery (MCA) and umbilical vein (UV), ductus venosus (DV), inferior caval vein (ICV) of the normal pregnancies among the 18-37th weeks and the term to determine the normal values of our population. Materials and Methods: Umblical, uterine, and fetal MCA with UV, DV, and ICV Doppler examinations were performed following the routine obstetric ultrasonographic evaluation once throughout the pregnancy and at the delivery of 163 normal pregnant with no maternal or Fetal complications at 18-24 (66 patient), 25-30 (53 patients) and 31-37 weeks (44 patients). The Systole/Diastole (S/D) rate for the arteries and the ICV, preload index for the DV, and mean velocity for the UV were used as the Doppler indexes. All color Doppler ultrasonographic examinations were performed by only one operator using the Siemens Acuson Antares machine and the CH4-1 MHz convex probe. Results: During the following weeks of the pregnancy, the S/D Doppler index and DV preload index were found to be decreased. No significant changes were found for the UV mean velocity. Results were statistically evaluated. Conclusion: As a result, venous structures and arterial parameters should be evaluated during the obstetric color Doppler ultrasonographic examination. The evaluation of these structures can be important for the early diagnosis of the conditions such as intrauterine growth retardation and hypoxia.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135403214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Degree of Correction Correlation with Clinical Outcomes in Adult Scoliosis Patients after Posterior Instrumentation Surgery 成人脊柱侧凸后路内固定手术后矫正程度与临床结果的相关性

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230921092721

Emre Bal, Onur Cetin

{"title":"The Degree of Correction Correlation with Clinical Outcomes in Adult Scoliosis Patients after Posterior Instrumentation Surgery","authors":"Emre Bal, Onur Cetin","doi":"10.5455/umj.20230921092721","DOIUrl":"https://doi.org/10.5455/umj.20230921092721","url":null,"abstract":"Introduction: Restoring sagittal and coronal parameters is a primary concern in adult scoliosis surgery, yet it remains challenging due to the matured bony structure. This study aims to analyze the relationship between clinical outcomes and the degree of correction achieved through posterior instrumentation surgery in adult scoliosis. Materials and Methods: This study evaluated the clinical and radiological results of 27 adult scoliosis patients who underwent posterior instrumentation, decompression, and correction surgery. Preoperative and follow-up X-rays were performed to assess Cobb angle, sagittal balance, and coronal balance. Visual Analog Score (VAS) and Oswestry Disability Index (ODI) were evaluated preoperatively and at follow-up. Results: The study comprised 27 patients (18 female, 9 male) with a mean age of 68.2 years. Preoperative Cobb angle averaged 42.4°, reducing to 5.9° at final follow-up. Sagittal balance decreased from 30.6 mm preoperatively to 9.7 mm at final follow-up. Coronal balance improved from 22.3 mm preoperatively to 10.5 mm at 2-year follow-up. Preoperative Cobb angle showed a strong correlation with preoperative ODI (p=0.028) and postoperative ODI (p=0.014). Preoperative sagittal balance also correlated strongly with pre and postoperative ODI. However, postoperative Cobb angle and sagittal balance did not correlate with postoperative ODI (p<0.05). Conclusion: While restoring sagittal and coronal parameters is a primary concern in adult scoliosis surgery, the degree of correction achieved does not necessarily correlate with clinical outcomes. Surgeons should consider this when planning surgery, and patients should be informed accordingly.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135843620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Risk Factors Associated with Post-conisation HPV Persistence during the COVID-19 Pandemic 评估与COVID-19大流行期间锥形后HPV持续存在相关的危险因素

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230506025428

S. Ayhan, G. Comert, T. Arslanca, Irem Kar, O. Turkmen, B. Ersak, O. Ceylan, M. Şahin, F. Kılıç, A. Turan

{"title":"Evaluation of the Risk Factors Associated with Post-conisation HPV Persistence during the COVID-19 Pandemic","authors":"S. Ayhan, G. Comert, T. Arslanca, Irem Kar, O. Turkmen, B. Ersak, O. Ceylan, M. Şahin, F. Kılıç, A. Turan","doi":"10.5455/umj.20230506025428","DOIUrl":"https://doi.org/10.5455/umj.20230506025428","url":null,"abstract":"Introduction: This study aimed to evaluate the factors associated with high-risk human papillomavirus (hrHPV) persistence after excision during the COVID-19 pandemic. Materials and Methods: A retrospective design was performed involving 171 patients who were analyzed regarding hrHPV clearance after conisation or LEEP. The clinicopathological findings, vaccination for COVID-19, history of SARS-CoV-2, or taking medication for SARS-CoV-2 infection before the first postoperative HPV test were evaluated. Results: The rate of preoperative high-risk HPV type, including HPV 16 and/or HPV 18, was 56% of the patients (n=96). The post-excision hrHPV persistence rate was 30.4 % during the 6–36 months follow-up period. 76.6% of patients had their first after-excision HPV test between 6 and 12 months. The total surgical margin was positive in 15 (8.8%) patients. The rate of vaccination, positivity of SARS-CoV-2 infection history, and taking medication for COVID-19 infection were 35.1% (n:60), 15.8% (n:27), and 9.4% (n:16), respectively. The rate of smoking was 35.7%. None of the evaluated factors were significantly related to HPV persistence after excision. Conclusion: No risk factors related to post-excisional HPV persistence were determined amongst age, clinic-pathological factors, vaccination for COVID-19, history of SARS-CoV-2 infection, or taking medication for SARS-CoV-2 infection during the COVID-19 pandemic.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82405496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unusual Mid-Line Nasal Mass in a Child: A Case Report 儿童鼻中线异常肿块1例

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230518033004

A. Zhanbaeva, Oguz Guvenmez, H. Keskin, A. Zhanbaev

{"title":"An Unusual Mid-Line Nasal Mass in a Child: A Case Report","authors":"A. Zhanbaeva, Oguz Guvenmez, H. Keskin, A. Zhanbaev","doi":"10.5455/umj.20230518033004","DOIUrl":"https://doi.org/10.5455/umj.20230518033004","url":null,"abstract":"Congenital midline nasal masses are rare anomalies with a prevalence of 1 in 20,000 to 40,000 births. These masses include nasal glioma, dermoid cyst, lipoma, hemangioma, and encephalocele. Timely diagnosis and appropriate surgical management are essential for optimal outcomes. We report the case of a 3-year-old girl presenting with a firm, non-fixed, slightly erythematous midline nasal mass, which was present at birth but increased in size over time, and a right nasal encephalocele. Radiological evaluation, including computed tomography (CT) and magnetic resonance imaging (MRI), confirmed the presence of both lesions with no connection between them. Initially, the right nasal encephalocele was endoscopically repaired. Subsequently, an incision was made in the midline nasal dorsum, and the nasal dorsal mass was successfully excised. Postoperative recovery was uneventful, and the patient was discharged without complications. The pathological examination of the excised nasal dorsum sample revealed a dark-colored, thick, malodorous material and hair follicles on macroscopic inspection. Microscopic inspection revealed the presence of skin appendages and hair follicles, findings consistent with a dermoid cyst. This case report highlights the co-occurrence of an encephalocele and a dermoid cyst, emphasizing the importance of thorough radiographic evaluation for accurate diagnosis. The surgical management, a novel technique, included skin closure using an advancement flap without grafting, resulting in a faster patient recovery time and a reduced hospital stay.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73359905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the Diagnostic Value of MRCP, CT, and Ultrasonography in Choledochal Stones with the Results of ERCP: Evidence from 1152 Case 1152例胆总管结石MRCP、CT、超声与ERCP诊断价值的比较

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20221205103820

E. Uğurlu, O. Dere, S. Yılmaz

{"title":"Comparison of the Diagnostic Value of MRCP, CT, and Ultrasonography in Choledochal Stones with the Results of ERCP: Evidence from 1152 Case","authors":"E. Uğurlu, O. Dere, S. Yılmaz","doi":"10.5455/umj.20221205103820","DOIUrl":"https://doi.org/10.5455/umj.20221205103820","url":null,"abstract":"Introduction: Endoscopic retrograde cholangiopancreatography (ERCP), magnetic resonance cholangiopancreatography (MRCP), computed tomography (CT), and ultrasonography (US) are widely used in the diagnosis of choledochal stones. This study aims to determine the sensitivity and diagnostic contribution of US, CT, and MRCP in detecting common bile duct stones and to compare them with ERCP. Materials and Methods: The study included 1152 patients who underwent ERCP diagnosed with choledochal stones. Initially, each patient underwent USG, CT, and MRCP. ERCP was performed 2-7 days later. The results were compared with the ERCP results. Sensitivity, specificity, positive predictive value (PPV), Negative Predictive Value (NPV), and F1 score were calculated. Results: Compared to ERCP, the most effective method in the diagnosis of choledocholithiasis is MRCP (F score: 0.84), CT (F score: 0.73), MR+BT (F score: 0.75), MR+BT+USG (F score: 0.55), and US (F score: 0.43). Conclusions: ERCP is the gold standard in treating stones in the common bile duct. However, since this method is invasive, its use for diagnostic purposes has decreased due to the possibility of complications. In diagnosing common choledochal stones, MRCP alone is sufficient regardless of other imaging methods.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91098133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Body Mass Index on Clinical Characteristics and Treatment Outcomes in Endometrial Cancer Patients: A Comprehensive Analysis 体重指数对子宫内膜癌患者临床特征及治疗结果影响的综合分析

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230822070551

Behzat Can

{"title":"The Impact of Body Mass Index on Clinical Characteristics and Treatment Outcomes in Endometrial Cancer Patients: A Comprehensive Analysis","authors":"Behzat Can","doi":"10.5455/umj.20230822070551","DOIUrl":"https://doi.org/10.5455/umj.20230822070551","url":null,"abstract":"Introduction: The study investigates the influence of Body Mass Index (BMI) on demographic and clinical characteristics, the choice of treatment modalities, and their potential impact on treatment response and prognosis in endometrial cancer. Materials and Methods: This retrospective cohort study analyzed individuals diagnosed with endometrial cancer who underwent gynecological surgical interventions. BMI was calculated as weight (kg) divided by height (m) squared and categorized into four subgroups: overweight (BMI 25-29.9), obesity class 1 (BMI 30-34.9), obesity class 2 (BMI 35-39.9), and obesity class 3 (BMI ≥40). Demographic and clinical data were extracted from medical records. Results: Menopausal status differed across subgroups (p=0.013), with obesity class 3 showing a higher proportion of premenopausal women. Diabetes mellitus prevalence was higher in obesity class 3 (p=0.044). The usage of radiotherapy, brachytherapy, chemotherapy, and radiochemotherapy were similar across subgroups, as were relapse rates. The most commonly performed surgery was TAH+BSO+PPLND across all subgroups, with the highest percentage in the obesity class 3 (68.4%). The distribution of surgery types showed no difference across BMI subgroups (p=0.569). Conclusion: Our study highlights the potential influence of BMI on menopausal status and surgical treatment strategies in endometrial cancer patients. The findings emphasize the importance of considering BMI in managing endometrial cancer, given the rising global prevalence of obesity.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Antibiotic Resistance of Patients with Ventriculoperitoneal Shunt Infection 脑室-腹腔分流术感染患者抗生素耐药性评估

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230320013100

F. Karakoç, Ozhan Orhan, Selda Karakoc, F. Aktar

{"title":"Evaluation of Antibiotic Resistance of Patients with Ventriculoperitoneal Shunt Infection","authors":"F. Karakoç, Ozhan Orhan, Selda Karakoc, F. Aktar","doi":"10.5455/umj.20230320013100","DOIUrl":"https://doi.org/10.5455/umj.20230320013100","url":null,"abstract":"Introduction: Cerebrospinal fluid (CSF) shunts carry CSF to other body parts for absorption in cases of hydrocephalus. However, infections seen in these systems are serious problems that cause the shunt to fail and cause high mortality. The study aimed to evaluate the epidemiological, clinical, and laboratory findings of cases with a ventriculoperitoneal shunt (VPS) due to hydrocephalus and who developed shunt infection and to determine the antibiotic resistance of microorganisms that cause shunt infection. Materials and Methods: This study was conducted in Dicle University Faculty of Medicine, Department of Child Health and Diseases, Department of Pediatric Infectious Diseases, between January 2014 and November 2016. Eighty-one cases of VPS infection, aged between 0 and 18, regardless of gender, were analyzed retrospectively. Results: Gram-positive and negative microorganisms were grown in the CSF culture in 64.1% and 35.9% of patients. The most commonly grown gram-positive microorganism was coagulase-negative staphylococcus, while the most commonly grown gram-negative microorganism was Acinetobacter sp. The most effective antibiotics against gram-positive bacteria were vancomycin, teicoplanin, and linezolid. The most effective antibiotics against gram-negative bacteria were colimycin, amikacin, ceftazidime, and meropenem. 21% of the cases died. Conclusion: If VPS infections are not treated correctly, especially in childhood, they progress to severe mortality and morbidity. Therefore, first of all, measures should be taken to prevent the formation of shunt infections, and we believe that long-term hospitalization rates and high treatment costs can be avoided by choosing appropriate and correct antibiotic regimens to prevent increasing antibiotic resistance.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83687878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and Management of ERCP Complications: The Results of 15000 Cases from Two Centers ERCP并发症的诊断和处理:两个中心15000例的结果

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20221219050725

E. Uğurlu, S. Yılmaz

{"title":"Diagnosis and Management of ERCP Complications: The Results of 15000 Cases from Two Centers","authors":"E. Uğurlu, S. Yılmaz","doi":"10.5455/umj.20221219050725","DOIUrl":"https://doi.org/10.5455/umj.20221219050725","url":null,"abstract":"Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) is a method of diagnosing and treating pancreaticobiliary diseases. ERCP differs from other endoscopic procedures with a greater risk of developing complications. The study aims to share experiences in diagnosing and managing complications in 15000 ERCP cases performed by two general surgeons in two separate general surgery ERCP units in 13 years and to determine appropriate diagnosis and treatment approaches in patients with complications. Materials and Methods: This study retrospectively evaluated the data of 15000 patients who underwent ERCP with various diagnoses between June 2009 and June 2022 in General Surgery Clinics in two different centers. Age, sex, ERCP indications, comorbidity, and clinical findings of the patients were recorded. Results: All patients who underwent ERCP were divided into two groups according to the incidence of complications. The patients who developed complications had higher ages, hospitalization days, and intensive care unit admission rates. Comorbidity increased the rate of complication development: amylasemia and acute pancreatitis were the most developed complications, respectively. Women developed more post-ERCP pancreatitis (PEP). Pre-incision, the number of ERCPs applied was not found to affect PEP development. Choledochal stone was the most important indication for ERCP in patients who developed PEP. Conclusion: ERCP is an invasive procedure, and complications such as acute pancreatitis, hemorrhage, perforation, cholangitis, and cholecystitis develop after this procedure. Determining these complications and related risk factors will be beneficial in terms of patient satisfaction and health expenditures.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83322514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Barrier Gel and Free Fat Graft on the Formation of Epidural Fibrosis in the Laminectomy Model 屏障凝胶和游离脂肪移植对椎板切除术模型硬膜外纤维化形成的影响

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230510095834

Sami Engin, A. Akbaş, Volkan Kizilkaya

{"title":"The Effect of Barrier Gel and Free Fat Graft on the Formation of Epidural Fibrosis in the Laminectomy Model","authors":"Sami Engin, A. Akbaş, Volkan Kizilkaya","doi":"10.5455/umj.20230510095834","DOIUrl":"https://doi.org/10.5455/umj.20230510095834","url":null,"abstract":"Introduction: This study aims to compare the efficacy of ADCON-L and free fat graft used to prevent epidural fibrosis in the experimental laminectomy model in rabbits. Materials and Methods: Thirty adult male New Zealand-type white rabbits weighing 2500-3000 grams were used. Three groups of ten were formed. New subjects and all subjects who replaced subjects who died during the study and follow-up period were sacrificed at the end of the 12th week. Group 1 was determined as the control group. Free fat grafts were placed into the laminectomy areas in group 2. In group 3, ADCON-L was injected into the surgical area. Subjects were sacrificed at week 12. After decalcification, laminectomy zones were taken into routine tissue follow-up for histopathological examination. Results: When group-1 and group-3 were compared regarding fibroblastic proliferation, there was a statistically significant difference (p<0.001). When group-2 and group-3 were compared, it was determined that fibroblastic proliferation was statistically higher in group-2 (p<0.001). When group-1 and group-3 were compared in terms of collagen amount, the amount of collagen in group-3 was significantly less (p<0.001). When the groups were evaluated statistically regarding the adhesion of the scar tissue to the dura, there was a significant difference between group-1 and group-2 (p<0.01). Adhesion was significantly less in group-3 compared to group-2 (p<0.001). Conclusion: We concluded that ADCON-L did not cause FBS syndrome. So, ADCON-L is more successful than free fat graft in the prevention of epidural fibrosis after laminectomy in spinal surgery.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90717346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0