THE ULUTAS MEDICAL JOURNAL最新文献

Comparison of Midterm and Long-Term Effects of Cord Protection Methods on Left Ventricular Function in Mitral Valve Replacement Surgery 二尖瓣置换术中远期脐带保护方法对左心室功能影响的比较

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230201114207

Y. Arslanoğlu, H. Deniz, H. Ustunsoy

{"title":"Comparison of Midterm and Long-Term Effects of Cord Protection Methods on Left Ventricular Function in Mitral Valve Replacement Surgery","authors":"Y. Arslanoğlu, H. Deniz, H. Ustunsoy","doi":"10.5455/umj.20230201114207","DOIUrl":"https://doi.org/10.5455/umj.20230201114207","url":null,"abstract":"Introduction: Our study aimed to determine the effects of cord protection methods applied in Mitral valve replacement (MVR) surgery on left ventricular function. Materials and Methods: MVR surgery was performed on 634 patients using either single or combined procedures. Of these patients, 358 (56.5%) underwent conventional MVR surgery, 121 (19.1%) underwent total chordal protection, and 155 (24.4%) underwent posterior chordal preservation. All patients were evaluated as class 3 and 4 according to the New York functional classification (NYHA). Left ventricular diastolic end-diameter (SVDSD), left ventricular systolic end-diameter (SVSSD), end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF) were compared between groups. Results: The degree of valve insufficiency was 3 and 4 in patients with mitral insufficiency. The mortality risk for patients undergoing conventional surgical operations was 4.257 times higher (OR:4.25; 95%CI:1.22-14.76). The study showed positive effects of chordal protection on the clinical status and echocardiographic parameters of undergoing MVR surgery (p<0.01). Conclusion: We believe cord protection methods positively affect left ventricular function after MVR. In particular, total chordal protection will positively affect left ventricular function.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90689175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of the FDG-PET in the Staging of Patients with Differentiated Thyroid Cancer FDG-PET在分化型甲状腺癌分期中的作用

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230901081616

Ebuzer Kalender

{"title":"The Role of the FDG-PET in the Staging of Patients with Differentiated Thyroid Cancer","authors":"Ebuzer Kalender","doi":"10.5455/umj.20230901081616","DOIUrl":"https://doi.org/10.5455/umj.20230901081616","url":null,"abstract":"Introduction: This study aims to determine the role of the FDG-PET in the staging of patients with Differentiated Thyroid Cancer (DTC) who have high Tg levels after thyroidectomy. Material and methods: Thirty-three DTC patients who performed FDG-PET scans after thyroidectomy were selected for this retrospective study. All patients had Tg levels over 10 ng/ml. FDG-PET was performed on patients six weeks after surgery. 2 weeks later FDG-PET imaging, patients received 131-I radioiodine treatment (RIT) except those with lymph node involvement. After RIT, post-ablation therapy whole body scan (TWBS) was performed on the patients. Results: Twelve patients (36.4%) without involvement outside the thyroid bed, both on the FDG-PET and TWBS, were remissed completely. In 21 patients (63.4%), there was involvement outside the thyroid bed on the FDG-PET and/or TWBS. Eleven patients (33.3%) had distant organ involvement in the FDG-PET and/or TWBS. Patients with involvement outside the thyroid bed had higher Tg levels than others. The disease was completely or partially regressed in the patients with distant organ involvement who had negative FDG-PET scans and positive TWBS results. The disease tended to progress in patients with distant organ involvement who had higher SUVmax levels on FDG-PET. Conclusion: Our data suggest that the FDG-PET scan, performed on the DTC patients with high Tg levels at the time of staging, would be the right approach. This approach will be useful, especially in demonstrating lymph node involvement and predicting prognosis. The results of FDG-PET may also change the treatment management.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"51-52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Postoperative Follow-ups of Children Having the Glenn Procedure 儿童Glenn手术术后随访评价

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230712015152

Mehmet Talay, Onur Doyurgan

{"title":"Evaluation of Postoperative Follow-ups of Children Having the Glenn Procedure","authors":"Mehmet Talay, Onur Doyurgan","doi":"10.5455/umj.20230712015152","DOIUrl":"https://doi.org/10.5455/umj.20230712015152","url":null,"abstract":"Introduction: This study aimed to evaluate the treatment results, complications, and the factors affecting mortality in cases who were followed up postoperatively in the pediatric intensive care unit (PICU) after the Glenn shunt procedure. Materials and Methods: The duration of the patients on the pump during surgery, transition times to feeding, blood gas and other laboratory parameters, complications developed during follow-up in the intensive care unit, and exitus rates were evaluated retrospectively. Results: BDG was performed due to tricuspid atresia, the most common diagnosis (30.2%). In the evaluation of the relationship between postoperative patient findings and exitus, a positive correlation was found between the duration of inotropic support, early extubation, and the duration of HFNC therapy in all patients (p<0.05); and a negative correlation was found in terms of the fluid the patients received on the first day after surgery (p<0.05). In patients who developed complications, a negative correlation was observed only in terms of the fluid they received on the first day after surgery (p<0.05) Conclusions: In terms of all patients, it was observed that mortality increased with early extubation and prolonged duration of inotropic support and HFNC therapy, and it decreased as the fluid the patients received on the first day after surgery decreased. In patients who developed complications, it was only observed that mortality decreased as the fluid the patients received on the first day after surgery decreased.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Results of Patients Who Have Retrograde Intramedullary Nailing Surgery for Femur Supracondylar Fractures 股骨髁上骨折行逆行髓内钉手术治疗效果评价

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230427065545

E. Yılmaz, I. Ulusoy, A. Kıvrak, Servet İğrek, E. Yilmaz

{"title":"Evaluation of the Results of Patients Who Have Retrograde Intramedullary Nailing Surgery for Femur Supracondylar Fractures","authors":"E. Yılmaz, I. Ulusoy, A. Kıvrak, Servet İğrek, E. Yilmaz","doi":"10.5455/umj.20230427065545","DOIUrl":"https://doi.org/10.5455/umj.20230427065545","url":null,"abstract":"Introduction: Supracondylar femur fractures are usually seen after high-energy trauma. Our study evaluated the surgical results of patients who underwent retrograde intramedullary nailing surgery. Materials and Methods: Thirty patients were treated with retrograde intramedullary nailing for femoral supracondylar fractures in a single clinic between January 2015 and September 2018. The clinical, functional, and radiological findings were analyzed retrospectively. Demographic data of the patients in our study, length of hospital stay, time until surgery, presence of additional trauma, complication rates, type of trauma, HSS and NEER scoring criteria for functional evaluation, and AO classification were used to determine fracture types. Results: Eighteen (60%) patients had high-energy trauma as the etiological cause, while 12 (40%) had fractures due to low-energy trauma. There were four open fractures and 26 closed fractures in the patients. The patients were evaluated according to the HSS and NEER evaluation systems. According to the HSS scoring system, 8 (26.7%) had excellent, 9 (30%) good, 12 (40%) moderate, and 1 (3%) poor results. According to the NEER scoring system, 7 (23.3%) excellent, 10 (33.3%) good, and 13 (43.4%) intermediate results were obtained. Conclusion: In supracondylar femur fractures, retrograde intramedullary nailing is a method that should be preferred in appropriate cases because of the low amount of bleeding, rapid mobilization, good union since the fracture hematoma is not evacuated, and good postoperative functional results.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85565336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations COVID-19感染与伯格氏病相关性截肢的关系

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230903113816

Mehmet Yilmaz, Nevzat Gonder

{"title":"Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations","authors":"Mehmet Yilmaz, Nevzat Gonder","doi":"10.5455/umj.20230903113816","DOIUrl":"https://doi.org/10.5455/umj.20230903113816","url":null,"abstract":"Introduction: Thromboangiitis obliterans (TAO) or Buerger's disease is a non-atherosclerotic, inflammatory arteritis involving small and medium-sized arteries and veins of the extremities, often causing gangrene and scarring. Coronavirus disease (COVID-19) may predispose to both arterial and venous thromboembolic complications. This study examined the relationship between COVID-19 infection and Buerger's disease-related amputations. Materials and Methods: Between January 2018 and July 2023, 54 patients who applied to our clinic for Buerger's disease and were followed up and treated were analyzed retrospectively. Follow-up information, demographic data of patients (age, gender, body mass index (BMI), education status), when they were diagnosed, amount of smoking (pack/year), all treatments applied for Buerger's disease (Pre-Covid – Covid period – Covid Afterwards), presence or absence of limb amputation, continued smoking, medications, cardiovascular risk factors, Charlson Comorbidity Index (CCI), Venous Thromboembolic Event (Pulmonary Embolism), Covid-19 History and vaccination information were noted. Results: The mean age of 54 patients included in the study was 38.1 (27-49), all male. The mean smoking rate was 32 (16 - 60) packs/year, and the mean exposure to the SARS-CoV-2 virus was 1.22 (0-4) times. There was a significant correlation between major amputations due to Buerger's disease and age, severity of COVID-19 disease, and systemic hypertension (p<0.005). Major amputation rates increased during the period of COVID-19 disease (p<0.05). Conclusion: We found a statistically significant increase in major amputations as the exposure to the virus or the severity of the COVID-19 disease increased. We also observed a significant increase in major amputation rates in the presence of systemic hypertension. The presence of COVID-19 disease and hypertension should be considered when planning treatment to prevent amputation in Buerger's patients.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Dietary Protein Quality on Short-Term Satiety and Daily Energy Intake 饲粮蛋白质质量对短期饱腹感和日能量摄入的影响

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20221223105724

Nurgül Arslan, F. Çakıroğlu, B. Yaprak

{"title":"The Effect of Dietary Protein Quality on Short-Term Satiety and Daily Energy Intake","authors":"Nurgül Arslan, F. Çakıroğlu, B. Yaprak","doi":"10.5455/umj.20221223105724","DOIUrl":"https://doi.org/10.5455/umj.20221223105724","url":null,"abstract":"Introduction: Some protein structures in the structure of foods are known to provide long-lasting satiety. Depending on the food source, this period of satiety can be shortened or lengthened. It has been reported that in diets for treating obesity in which long-term satiety is a goal, animal-derived proteins can help people feel fuller for longer. This study aimed to examine the effects on satiety markers after breakfast of consuming breakfast foods prepared with different protein sources. Materials and Methods: The study included 40 participants but concluded with 39 participants. Sixteen males and 23 females participated in the research. The participants in the study were randomly assigned to begin the investigation. After 12 hours of fasting, the study participants were offered two breakfasts on separate days. Two distinct breakfasts consisting of foods of animal origin and foods of vegetable origin were served. Results: The breakfasts had similar calories, protein, fat, carbohydrates, and fiber. Before and after breakfast, a VAS scale with seven satiety markers was created and applied. The scale was applied 0 minutes before breakfast, 30 minutes, 60 minutes, 120 minutes, and 180 minutes after breakfast. After breakfast, it was observed that the satiety markers of animal origin had a longer duration and higher scores than those of plant origin. Conclusion: In cases where energy restriction is necessary, it has been determined that increasing the protein quality in the foods consumed can provide long-term satiety regardless of the amount consumed.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72548955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do The Videos About Hallux Rigidus On YouTube Generally Exhibit High Quality? YouTube上关于拇僵直的视频是否普遍表现出高质量?

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230905100234

Mehmet Yilmaz

{"title":"Do The Videos About Hallux Rigidus On YouTube Generally Exhibit High Quality?","authors":"Mehmet Yilmaz","doi":"10.5455/umj.20230905100234","DOIUrl":"https://doi.org/10.5455/umj.20230905100234","url":null,"abstract":"Introduction: Hallux Rigidus is a disease characterized by pain and weakness in the first metatarsophalangeal joint of the foot. Patients with this condition describe severe pain when walking and taking steps. Research on the quality of information available on the Internet is lacking. Our study aimed to analyze the videos about Hallux Rigidus on YouTube, one of the video-sharing applications. Methods: Our research is based on data collected from a video-sharing site (YouTube) on 12 July 2023. The search is done through the configuration process. \"Change hallux\" was typed into the search engine. The popularity of the video was analyzed using the Video Power Index (VPI) [(Like/(Like+Dislike)) x 100]. Videos were classified into five different groups based on the source they were uploaded to: [1] Community/Nonprofits, [2] Medical Professionals, [3] Medical school patients, [4] Universities / Schools, and [5] Patients / Independent users / Other places. The quality of movies is evaluated with the Global Quality Score (GQS). All videos were evaluated by one surgeon. A modified DISCERN scale was used to assess the reliability and quality of information provided in the videos. Results: Fifty videos were analyzed in this study. The average number of views of the video is 6507, and the average length is 958 seconds. When the video-based scores of the DISCERN variable were compared with the GQS, the scores of the patient/independent user/other group were lower, but it was not significant (p>0.05). Conclusion: We believe the content of this video is good and informative. Do not use channels other than healthcare providers or dubious channels, as videos uploaded by individuals can be misleading.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"238 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome 代谢综合征患者血清铁蛋白水平与胰岛素抵抗的关系

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230119123818

U. Yurekli, Rıza Altunbaş

{"title":"The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome","authors":"U. Yurekli, Rıza Altunbaş","doi":"10.5455/umj.20230119123818","DOIUrl":"https://doi.org/10.5455/umj.20230119123818","url":null,"abstract":"Introduction: Insulin resistance and metabolic syndrome (MetS) are risk factors for diabetes mellitus, and their prevalence is increasing. Ferritin has emerged as a biomarker of low-grade inflammation in addition to its role in iron metabolism. The study aims to determine the correlation between ferritin and insulin resistance (IR) in MetS. Materials and Methods: In this study, ferritin, glucose (fasting), and HOMA-IR were measured from serum samples obtained from 98 MetS patients and 100 healthy volunteers. Serum ferritin, glucose, insulin, and HOMA-IR results were compared between the MetS and the control group. Correlation analysis was performed between ferritin and HOMA-IR in control and MetS patients. Results: Serum ferritin (Control: 93,9±30,13; MetS:200±57,31 ng/ml), glucose (Control: 100,9±11,86, 123,9±21,52 ng/dl), insulin (Control: 4,11±2,57; MetS:15,99±5,71 µU/ml) and HOMA-IR (Control: 1,04±0,74; MetS:5,07±2,33) revealed to be higher in MetS compared to control. The correlation between serum ferritin level and HOMA-IR in MetS patients was revealed. This correlation was not found in the control group. Conclusion: In MetS, high serum ferritin level increases insulin resistance. While the positive correlation of ferritin with insulin resistance occurs at high ferritin levels, this is not observed at low ferritin levels.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83340290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Midazolam and Magnesium Sulfate on Preoperative Anxiety in Patients Undergoing Rhinoplasty Operation 咪达唑仑和硫酸镁对鼻整形手术患者术前焦虑的影响

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230111112358

H. Demirkiran, Hilmi Yetkin, C. Kacar, C. Demir, A. Tekeli

{"title":"The Effect of Midazolam and Magnesium Sulfate on Preoperative Anxiety in Patients Undergoing Rhinoplasty Operation","authors":"H. Demirkiran, Hilmi Yetkin, C. Kacar, C. Demir, A. Tekeli","doi":"10.5455/umj.20230111112358","DOIUrl":"https://doi.org/10.5455/umj.20230111112358","url":null,"abstract":"Introduction: Preoperative anxiety is a common psychological condition caused by many factors and can affect anesthesia results, postoperative analgesia, and surgery. This study investigated the effects of midazolam and midazolam combined with magnesium sulfate on preoperative anxiety. Materials and Methods: Sixty patients in the ASA I-II group, aged between 18-60 years, undergoing rhinoplasty operations were included in the study. Patients included in the study were randomly divided into two groups using the sealed envelope method. The first group (Group M; n:30) received 0.02-0.04 mg/kg midazolam in 100 ml isotonic, and the second group (Group MM; n:30) received 2g magnesium sulfate+0.02-0.04 mg/kg midazolam in 100 ml isotonic administered intravenously 15 minutes before surgery. In addition, state-trait anxiety inventory (STAI-TX) was evaluated preoperatively at 0. minutes and postoperative at 0., 3., 6. hours and the visual analog scale (VAS) was evaluated at 0., 3., and 6. hours postoperatively. Results: 66.7% were female (n:40), 56.7% were ASA-I (n:34), the mean age was 26.17±5.57(18-41) years, and the mean surgery time was 64±12.64 (35-90) minutes. There was no statistically significant difference between the groups regarding age, gender, ASA, and surgical duration of the cases. In addition, heart rate, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, and VAS decreased compared to preoperative values, while TOF and STAI-TX values increased in both the M and the MM groups. Conclusion: Midazolam and midazolam-magnesium sulfate can be safe and effective for preoperative anxiety.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74054186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study 不孕男性抗氧化剂水平的调查:一项前瞻性横断面研究

THE ULUTAS MEDICAL JOURNAL Pub Date : 2023-01-01 DOI: 10.5455/umj.20230815053224

Mehmet Taskiran

{"title":"Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study","authors":"Mehmet Taskiran","doi":"10.5455/umj.20230815053224","DOIUrl":"https://doi.org/10.5455/umj.20230815053224","url":null,"abstract":"Introduction: The escalating rate of infertility, especially with many of its causes remaining enigmatic, necessitates advanced investigative measures. This study explores the correlation between various biochemical, hormonal, hematological, and oxidative stress parameters in infertile male patients and their sperm parameters. Materials and Methods: From January to July 2023, blood samples of infertile male patients from our outpatient clinic were examined for aforementioned parameters. Patients were categorized into four groups based on their sperm parameters: Group 1 (Normal), Group 2 (Asthenospermia), Group 3 (Oligospermia), and Group 4 (Azoospermia). Results: Infertility duration, FSH, LH, prolactin, and testicular volume (both left and right) varied significantly among the groups (p<0.01). Significant differences were also noted in monocyte, eosinophil, TAS, TOS, OSI, CRP, and ESR levels (p<0.01). Specifically, azoospermia positively correlated with increased Monocyte, TOS, OSI, CRP, and ESR levels (p-values and correlation coefficients ranging from p=0.012, r: 0.141 to p<0.001, r: 0.551). Logistic regression pinpointed TAS, TOS, OSI, and ESR as significant differentiation risk factors. According to ROC analysis, these factors were critical prognosticators for azoospermia. Conclusion: Elevated TOS and OSI, coupled with decreased TAS levels, were linked to monocytes, CRP, and ESR in azoospermia. Thus, TAS, TOS, OSI, and ESR can be pivotal diagnostic tools for infertility, and their evaluation from routine blood samples could streamline the diagnosis and treatment response assessment of infertility.","PeriodicalId":23051,"journal":{"name":"THE ULUTAS MEDICAL JOURNAL","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135402960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0