Therapeutic Apheresis and Dialysis最新文献

{"title":"A Study Over Brain Connectivity Network of Parkinson's Patients, Using Nonparametric Bayesian Model.","authors":"Fatemeh Pourmotahari, Seyyed Mohammad Tabatabaei, Nasrin Borumandnia, Naghmeh Khadembashi, Keyvan Olazadeh, Hamid Alavimajd","doi":"10.32598/bcn.2021.3217.1","DOIUrl":"10.32598/bcn.2021.3217.1","url":null,"abstract":"<p><strong>Introduction: </strong>Parkinson disease is a neurodegenerative disease that disrupts functional brain networks. Many neurodegenerative disorders are associated with changes in brain communication patterns. Resting-state functional connectivity studies can distinguish the topological structure of Parkinson patients from healthy individuals by analyzing patterns between different regions of the brain. Accordingly, the present study aimed to determine the brain topological features and functional connectivity in patients with Parkinson disease, using a Bayesian approach.</p><p><strong>Methods: </strong>The data of this study were downloaded from the open neuro site. These data include resting-state functional magnetic resonance imaging (rs-fMRI) of 11 healthy individuals and 11 Parkinson patients with mean ages of 64.36 and 63.73, respectively. An advanced nonparametric Bayesian model was used to evaluate topological characteristics, including clustering of brain regions and correlation coefficient of the clusters. The significance of functional relationships based on each edge between the two groups was examined through false discovery rate (FDR) and network-based statistics (NBS) methods.</p><p><strong>Results: </strong>Brain connectivity results showed a major difference in terms of the number of regions in each cluster and the correlation coefficient between the patient and healthy groups. The largest clusters in the patient and control groups were 26 and 53 regions, respectively, with clustering correlation values of 0.36 and 0.26. Although there are 15 common areas across the two clusters, the intensity of the functional relationship between these areas was different in the two groups. Moreover, using NBS and FDR methods, no significant difference was observed for each edge between the patient and healthy groups (P>0.05).</p><p><strong>Conclusion: </strong>The results of this study show a different topological configuration of the brain network between the patient and healthy groups, indicating changes in the functional relationship between a set of areas of the brain.</p>","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":"16 1","pages":"61-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85358942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between hyponatremia, inflammation, and mortality in patients undergoing peritoneal dialysis: A nationwide observations","authors":"Bulent Erdogan, Naim Ata, Murat Caglayan, Melih Gaffar Gözükara, Emin Gemcioglu, Fevzi Coskun, Nuray Yilmaz, Osman Celik, Mustafa Okan Ayvali, Mustafa Mahir Ulgu, Suayip Birinci","doi":"10.1111/1744-9987.14092","DOIUrl":"https://doi.org/10.1111/1744-9987.14092","url":null,"abstract":"Hyponatremia is the most common electrolyte disorder often present in peritoneal dialysis (PD) patients. The aim of this retrospective study was to investigate the effect of hyponatremia on mortality in patients undergoing PD.","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":"15 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138630165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic plasma exchange for refractory Kawasaki disease in children weighing less than 10 kg","authors":"Mariko Sawada, Kayo Ogino, Tomohiro Hayashi, Kenji Waki","doi":"10.1111/1744-9987.14099","DOIUrl":"https://doi.org/10.1111/1744-9987.14099","url":null,"abstract":"Therapeutic plasma exchange (TPE) is used for treating refractory Kawasaki disease (KD); however, there are few reports on its use in small children.","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":"4 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138630031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound findings of the sternoclavicular and shoulder joints in patients on maintenance hemodialysis","authors":"Lin Zhai, Siyu Wang, Fei Xue, Ying Yao","doi":"10.1111/1744-9987.14093","DOIUrl":"https://doi.org/10.1111/1744-9987.14093","url":null,"abstract":"Ultrasonographic examination of joints is a non-invasive method to detect and monitor Dialysis-associated amyloidosis (DRA).","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":"3 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138573972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal carnitine metabolism in hemodialysis patients on different anticoagulants","authors":"Kie Sekiguchi, Takaya Abe, Ei Shiomi, Daiki Ikarashi, Tomohiko Matsuura, Shigekatsu Maekawa, Renpei Kato, Mitsugu Kanehira, Ryo Takata, Jun Sugimura, Takashi Sekiguchi, Wataru Obara","doi":"10.1111/1744-9987.14096","DOIUrl":"https://doi.org/10.1111/1744-9987.14096","url":null,"abstract":"We aimed to determine whether unfractionated heparin (UH) and low molecular weight heparin (LH) contribute to aberrant carnitine metabolism in patients receiving hemodialysis.","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":"86 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138629870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of therapeutic procedure for Waldenström's macroglobulinemia with hyperviscosity syndrome","authors":"Kenichi Ito, Tomoki Kawasaki, Kazuhiko Hirano, Naohiro Sekiguchi","doi":"10.1111/1744-9987.14094","DOIUrl":"https://doi.org/10.1111/1744-9987.14094","url":null,"abstract":"Hyperviscosity syndrome (HVS) is a significant complication in Waldenström's macroglobulinemia (WM), although the significance of plasmapheresis in clinical practice has not been clarified. To confirm the efficacy and safety of plasmapheresis followed by primary therapy for WM with HVS, we retrospectively conducted this study.","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":"77 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138561875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of serum urea-to-creatinine ratio in patients undergoing peritoneal dialysis.","authors":"Shun Tonomura,&nbsp;Kiyotaka Uchiyama,&nbsp;Takashin Nakayama,&nbsp;Ryunosuke Mitsuno,&nbsp;Daiki Kojima,&nbsp;Eriko Yoshida Hama,&nbsp;Tomoki Nagasaka,&nbsp;Erina Sugita Nishimura,&nbsp;Ei Kusahana,&nbsp;Rina Takahashi,&nbsp;Norifumi Yoshimoto,&nbsp;Shintaro Yamaguchi,&nbsp;Kohkichi Morimoto,&nbsp;Tadashi Yoshida,&nbsp;Kaori Hayashi,&nbsp;Takeshi Kanda,&nbsp;Naoki Washida,&nbsp;Hiroshi Itoh","doi":"10.1111/1744-9987.14030","DOIUrl":"10.1111/1744-9987.14030","url":null,"abstract":"<p><strong>Introduction: </strong>We aimed to determine the correlation between the serum urea-to-creatinine ratio and residual kidney function (RKF) in patients undergoing peritoneal dialysis (PD), as well as its predictive value for PD-related outcomes.</p><p><strong>Methods: </strong>This study included a cross-sectional study to assess the correlation between serum urea-to-creatinine ratio and RKF in 50 patients on PD and a retrospective cohort study to assess the association between serum urea-to-creatinine ratio and PD-related outcomes in 122 patients who initiated PD.</p><p><strong>Results: </strong>Serum urea-to-creatinine ratios had significant positive correlations with renal Kt/V and creatinine clearance values (r = 0.60, p < 0.001 and r = 0.61, p < 0.001, respectively). Additionally, serum urea-to-creatinine ratio was significantly associated with a lower risk of transfer to hemodialysis or PD/hemodialysis hybrid therapy (hazard ratio: 0.84, 95% confidence interval: 0.75-0.95).</p><p><strong>Conclusion: </strong>The serum urea-to-creatinine ratio can be an indicator of RKF and a prognostic factor in patients undergoing PD.</p>","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":" ","pages":"1103-1112"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9668271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of molnupiravir and sotrovimab in Japanese dialysis patients with COVID-19 in clinical practice during the Omicron (BA.1 and BA.2) pandemic.","authors":"Kan Kikuchi,&nbsp;Masaomi Nangaku,&nbsp;Munekazu Ryuzaki,&nbsp;Tomoyuki Yamakawa,&nbsp;Yoshihiro Ota,&nbsp;Norio Hanafusa,&nbsp;Ken Sakai,&nbsp;Yoshihiko Kanno,&nbsp;Ryoichi Ando,&nbsp;Toshio Shinoda,&nbsp;Shu Wakino,&nbsp;Hidetomo Nakamoto,&nbsp;Yoshiaki Takemoto,&nbsp;Tadao Akizawa","doi":"10.1111/1744-9987.14033","DOIUrl":"10.1111/1744-9987.14033","url":null,"abstract":"<p><strong>Introduction: </strong>In the present study, the efficacy of sotrovimab and molnupiravir in dialysis patients with COVID-19 was investigated using a registry of COVID-19 in Japanese dialysis patients.</p><p><strong>Methods: </strong>Dialysis patients with confirmed SARS-CoV-2 during the COVID-19 (Omicron BA.1 and BA.2) pandemic were analyzed. Patients were classified into four treatment groups: molnupiravir monotherapy (molnupiravir group), sotrovimab monotherapy (sotrovimab group), molnupiravir and sotrovimab combination therapy (combination group), and no antiviral therapy (control group). The mortality rates in the four groups were compared.</p><p><strong>Results: </strong>A total of 1480 patients were included. The mortality of the molnupiravir, sotrovimab, and combination groups were significantly improved compared to the control group (p < 0.001). Multivariate analysis indicated that antiviral therapy improves the survival of dialysis patients with COVID-19 (hazard ratio was 0.184 for molnupiravir, 0.389 for sotrovimab, and 0.254 for combination groups, respectively).</p><p><strong>Conclusion: </strong>Sotrovimab showed efficacy in Omicron BA.1 but attenuated in BA.2. Molnupiravir also showed efficacy in BA.2, suggesting administration of molnupiravir would be important.</p>","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":" ","pages":"1064-1069"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9795819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-dialysis fatigue and peri-dialytic serum lactate levels in patients on chronic hemodialysis.","authors":"Maurizio Bossola, Nunzia Ciferri, Enrico Di Stasio","doi":"10.1111/1744-9987.14034","DOIUrl":"10.1111/1744-9987.14034","url":null,"abstract":"","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":" ","pages":"1125-1126"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9749644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of self-remitting periaortitis in a hemodialysis patient after COVID-19.","authors":"Satoshi Matsui, Tomonaga Ameku, Shinji Ono","doi":"10.1111/1744-9987.14040","DOIUrl":"10.1111/1744-9987.14040","url":null,"abstract":"of self-remitting periaortitis in a hemodialysis patient after coronavirus disease 2019 (COVID-19","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":" ","pages":"1127-1128"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10247897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}