{"title":"Optical Coherence Tomography: Essential Tool in Macular Hole Management","authors":"S. Tinwala","doi":"10.5772/INTECHOPEN.79279","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.79279","url":null,"abstract":"Optical coherence tomography (OCT) is a noninvasive, diagnostic technique for accu- rately identifying and quantitatively characterizing macular holes. OCT is crucial in assessing fellow eyes of patients with a macular hole to detect preclinical changes leading to subsequent hole formation. The tomographic information provided by OCT, akin to an in vivo biopsy, has led to a better understanding of the pathogenesis of hole formation. The cross-sectional view produced by OCT effectively distinguishes full-thickness macu lar holes from mimicking conditions like lamellar holes, macular pseudoholes, and cysts, which may sometimes be difficult to differentiate clinically. This information enables early diagnosis and can guide the intervention of choice when treatment is deemed nec- essary. OCT is useful to prognosticate cases, thereby facilitating discussions with patients and managing visual expectations preoperatively. Intraoperative OCT (iOCT) can iden- tify intraoperative changes in the macular anatomy during surgery that can influence functional outcomes. Postoperatively, OCT is extremely useful for documenting serial changes in the foveal architecture and is helpful in correlating functional and anatomic outcomes. As the technology continues to improve, OCT has become indispensable for all aspects of patient care for macular holes.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116015090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OCT in Lamellar Corneal Transplantation","authors":"M. C. Ozmen, H. B. Özdemir","doi":"10.5772/INTECHOPEN.78294","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78294","url":null,"abstract":"","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126541871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. D. Moura, J. Novo, J. Rouco, N. Barreira, M. G. Penedo, M. Ortega
{"title":"Retinal Vasculature Identification and Characterization Using OCT Imaging","authors":"J. D. Moura, J. Novo, J. Rouco, N. Barreira, M. G. Penedo, M. Ortega","doi":"10.5772/INTECHOPEN.78292","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78292","url":null,"abstract":"The eye fundus is the part of the human body where the blood vessels can be directly observed and studied. For this reason, the analysis and diagnosis of many relevant diseases that affect the circulatory system, for example, reference, hypertension, diabetes or arteriosclerosis can be supported by the use of this source of information, analyzing their degree of severity and impact by the study of the properties of the retinal microcirculation. The development of computer aided-diagnosis tools became relevant over the recent years as they support and facilitate the work of specialists, helping to accurately identify the target structures in many processes of analysis and diagnosis. In that sense, the automatic identification of the retinal vasculature is crucial as its manual identification is an exhaustive and tedious work when it is manually performed by the experts. This chapter presents an analysis of the characteristics of the optical coherence tomography imaging and its potential for the retinal vascular identification and characterization. In that sense, we also analyze computational approaches to automatically obtain and characterize the retinal vasculature and provide an intuitive visualization that facilitates the posterior clinical analysis of relevant diseases such as hypertension or diabetes.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126751658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spectral Domain Optical Coherence Tomography in the Diagnosis and Monitoring of Diabetic Macular Edema","authors":"S. Nicoară","doi":"10.5772/INTECHOPEN.78681","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78681","url":null,"abstract":"Currently, spectral domain optical coherence tomography (SD-OCT) is a basic tool in diagnosing and monitoring diabetic macular edema (DME), which is the most frequent cause of visual impairment in the diabetic patients. OCT technology has changed the classification of DME from the traditional criteria. Macular thickness measured on OCT is considered an outcome measure to evaluate the structural and functional outcome of various therapeutic means used in DME. SD-OCT evaluates ultrastructural retinal parameters, such as the ellipsoid zone, photoreceptor outer segment length and quantifies the individual layers according to various algorithms. The aim is to present the way in which SD-OCT technology has changed our clinical practice during the last years, in diagnosing, classifying and treating DME and to illustrate its impact with practical cases.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114739133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Eppig, S. Mäurer, L. Daas, B. Seitz, A. Langenbucher
{"title":"Imaging the Cornea, Anterior Chamber, and Lens in Corneal and Refractive Surgery","authors":"T. Eppig, S. Mäurer, L. Daas, B. Seitz, A. Langenbucher","doi":"10.5772/INTECHOPEN.78293","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78293","url":null,"abstract":"Anterior segment OCT (AS-OCT) is an optical and noncontact imaging technology, which has numerous fields of application in the imaging of the cornea, anterior chamber, and the lens. In this chapter, we will present some of the application fields of AS-OCT in corneal, cataract, and refractive surgery. We will emphasize the potential of AS-OCT by several clinical examples including corneal imaging (keratoconus, keratoplasty, and refractive surgery) and intraocular lens imaging after refractive surgery. AS-OCT shows special potential for corneal imaging in case of corneal edema and for postoperative control after Descemet’s membrane endothelial keratoplasty (DMEK). The postoperative follow-up of a posterior chamber Collamer lens’ses vault and measuring the anterior chamber angle could be identified as another promising field of application for AS-OCT.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114866260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel Insight into Morphological Features and Vascular Profile of Selected Macular Dystrophies Using Swept-Source Optical Coherence Tomography and Optical Coherence Tomography Angiography","authors":"M. Moussa, M. Leila","doi":"10.5772/INTECHOPEN.78679","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78679","url":null,"abstract":"Our perception of macular dystrophies has evolved overtime from collective grouping into hereditary disorders of unclear etiology and no effective treatment to avid search for the underlying pathogenic mechanism that would provide base for future therapy. A causal conjunction between abnormalities in the photoreceptors layer and the RPE— Bruch’s membrane complex and abnormal profile of the retinal vascular plexuses and the choriocapillaris—stands out as a plausible theory of pathogenesis. The recently introduced swept-source optical coherence tomography (SS-OCT) technology incorpo- rates long-wavelength (1050-nm) scanning light, less susceptibility to sensitivity roll-off, and ultrahigh-speed image acquisition. These features enabled in vivo noninvasive visualization of different strata of the outer retina and the choriocapillaris with unprec edented finesse. Furthermore, the SS-OCT technology incorporated a blood flow detec - tion algorithm; OCTARA that in tandem with the deeper penetration and superior axial resolution of SS-OCT enabled detailed assessment of the retinal capillary plexuses and the choriocapillaris in terms of structure and density. This novel technology could help explore yet undiscovered frontiers in the pathophysiology of macular dystrophies and guide future therapeutic approaches. This chapter includes a review of literature along with the authors’ experience in imaging selected macular dystrophies using SS-OCT and SS-OCT angiography (SS-OCTA). stem cell transplantation before irreversible visual dysfunction sets in.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125337813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Use of OCT in the Management of Epiretinal Membranes","authors":"N. Acar","doi":"10.5772/INTECHOPEN.79770","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.79770","url":null,"abstract":"Epiretinal membranes (ERM) are frequently seen in an aging eye, especially after posterior vitreous detachment, and can cause decreased vision, and/or metamorphopsia. Not all of the ERMs detected in routine ophthalmological examination are indicated to be removed with surgery. Optical coherence tomography (OCT) examination reveals the microanatomy of all the retinal layers and enables the vitreoretinal surgeon to make decision to follow-up or to perform a vitrectomy to peel the ERM. OCT imaging clearly shows all the tractions on the retina and the intraretinal layers; and can have a prognostic value for the surgery. OCT imaging is also very valuable in the differential diagnosis of pseudoholes with macular and lameller holes; much better than the clinical examination. It is a routine part of the detailed retinal examination of an eye with an ERM. This chapter covers OCT findings in ERMs, and examples of cases with ERMs indicated for surgery of follow-up will be shown, explaining the clinical results of the cases.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125330244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"iOCT in PVR Surgical Management","authors":"Salvatore Di Lauro, S. P. Idoate, J. Pastor","doi":"10.5772/INTECHOPEN.78774","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78774","url":null,"abstract":"Recent advances in optical coherence tomography (OCT) technology have allowed the introduction of OCT into the operating room. Intraoperative OCT (iOCT) has been utilized to visualize the retinal architecture prior, during, and following several retinal surgical technics. The identification of epiretinal, subretinal, and intraretinal changes is one of the crucial points in PVR management. The iOCT can identify intraretinal changes and/ or subretinal PVR membranes which cannot be easily peeled as epiretinal membranes. Intraretinal forms are especially difficult to identify preoperatively but their presence may be crucial in surgical management because the attempt to remove the presumed membrane may result in severe retinal tissue damage and iatrogenic tears. Therefore, surgical technique and even tamponade choice may be seriously affected by OCT imaging results.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"153 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120932651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OCT in Glaucoma Diagnosis, Detection and Screening","authors":"Aydın Yildiz","doi":"10.5772/INTECHOPEN.78683","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.78683","url":null,"abstract":"Glaucoma is a chronic and progressive optic neuropathy in which increased intraocular pressure is the most important risk factor in the etiopathogenesis. The basic pathology is the progressive loss of retinal ganglion cells (RGCs) especially the death of the axons of ganglion cells initially (apoptosis), followed by peripapillary retinal nerve fiber layer (RNFL) defects. Since optical coherence tomography (OCT)’s first demonstration in 1991 by Huang et al. and introduction commercially in 1996, it began gaining popularity in 2000s for retinal evaluation and the detection, diagnosis, and follow-up of glaucoma. Previously available OCT instruments used a technique referred to as time-domain (TD-) OCT, followed by spectral-domain (SD-) OCT, which has an increased scan acquisition rate, allowing for a more detailed sampling of the area of interest. Recently, swept-source OCT (SS-OCT), a newer generation of OCT, has been introduced. Clinical assessment using multiple parameters, including peripapillary RNFL, ganglion cells, optic nerve head, and macular parameters, has proven useful for managing and diagnosing glaucoma as well as for evaluating risk in glaucoma suspects. In this chapter, we aim to evaluate the use of OCT and its modalities in diagnosis, screening, and progression of glaucoma.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127651418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OCT Application Before and After Cataract Surgery","authors":"Xiaogang Wang, Jing Dong, Suhua Zhang, Bin Sun","doi":"10.5772/INTECHOPEN.77281","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.77281","url":null,"abstract":"Optical coherence tomography (OCT), especially anterior segment OCT (AS-OCT), plays an important role in ophthalmology. With the technology evolving from time-domain to spectral-domain, more and more detailed ocular information has become available. Anterior segment OCT provides particularly useful information for cataract surgeons. This chapter focuses mainly on AS-OCT evaluation of eyes before and after cataract surgery. Four aspects including: (1) anterior lens capsule and lens epithelium evaluation using spectral-domain OCT (SD-OCT); (2) investigation of clear corneal incision in femtosecond laser assisted cataract surgery using SD-OCT; (3) capsular block syndrome evaluation before and after treatment using SD-OCT; (4) IOL power calculation in post- myopic excimer laser eyes using SD-OCT, will be discussed in this chapter.","PeriodicalId":228355,"journal":{"name":"OCT - Applications in Ophthalmology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125488847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}