The Journal of Nutrition Health and Aging最新文献

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Effect of a Resistance Training Program on Sarcopenia and Functionality of the Older Adults Living in a Nursing Home. 阻力训练计划对疗养院老年人肌肉疏松症和功能的影响
The Journal of Nutrition Health and Aging Pub Date : 2019-01-01 DOI: 10.1007/s12603-019-1261-3
J Martín Del Campo Cervantes, M Habacuc Macías Cervantes, R Monroy Torres
{"title":"Effect of a Resistance Training Program on Sarcopenia and Functionality of the Older Adults Living in a Nursing Home.","authors":"J Martín Del Campo Cervantes, M Habacuc Macías Cervantes, R Monroy Torres","doi":"10.1007/s12603-019-1261-3","DOIUrl":"10.1007/s12603-019-1261-3","url":null,"abstract":"<p><strong>Importance: </strong>There are currently few evidence about resistance training as a treatment for sarcopenia in the nursing home setting.</p><p><strong>Objective: </strong>To evaluate the effect of a resistance training program on the sarcopenia and functionality of the elderly living in a nursing home.</p><p><strong>Design, setting, and participants: </strong>A blinded longitudinal intervention study conducted in elderly people living in a nursing home from August to November 2016. Participants included a convenience sample of 19 older adults.</p><p><strong>Intervention: </strong>We prescribed a resistance exercise program three times a week for 12 weeks. The scheme was two to three sets with eight to 15 repetitions per exercise.</p><p><strong>Main outcome and measures: </strong>The primary outcome was an increase in muscle strength and an improvement in physical performance of the elderly people living in nursing homes.</p><p><strong>Results: </strong>19 older adults between 77.7 ± 8.9 years old, completed the 12 week resistance exercise program achieving a significant increase in muscle strength to 5.7 Kg (p = 0.0001) as well as nutritional intake for the first four weeks (p = 0.001); we found an improvement in physical performance (p = 0.0001) in balance (p = 0.0001), chair stand (p = 0.036) and gait speed (p = 0.0001). Of the 47.4% that reached sarcopenia degree, in the end it was 33.3%. A relationship with nutritional status (p = 0.004) and age (p = 0.019) was found with the initial and final handgrip strength (p = 0.041).</p><p><strong>Conclusions and relevance: </strong>The resistance training program improves the functionality (muscle strength and physical performance), with the benefit of the decrease in severe sarcopenia.</p>","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81126465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indicator Amino Acid-Derived Estimate of Dietary Protein Requirement for Male Bodybuilders on a Nontraining Day Is Several-Fold Greater than the Current Recommended Dietary Allowance. 男性健美运动员在非训练日的膳食蛋白质需要量的氨基酸来源估计比目前推荐的膳食摄入量高出几倍。
The Journal of Nutrition Health and Aging Pub Date : 2017-05-01 DOI: 10.3945/jn.116.236331
A. Bandegan, G. Courtney-Martin, M. Rafii, P. Pencharz, P. Lemon
{"title":"Indicator Amino Acid-Derived Estimate of Dietary Protein Requirement for Male Bodybuilders on a Nontraining Day Is Several-Fold Greater than the Current Recommended Dietary Allowance.","authors":"A. Bandegan, G. Courtney-Martin, M. Rafii, P. Pencharz, P. Lemon","doi":"10.3945/jn.116.236331","DOIUrl":"https://doi.org/10.3945/jn.116.236331","url":null,"abstract":"Background: Despite a number of studies indicating increased dietary protein needs in bodybuilders with the use of the nitrogen balance technique, the Institute of Medicine (2005) has concluded, based in part on methodologic concerns, that \"no additional dietary protein is suggested for healthy adults undertaking resistance or endurance exercise.\"Objective: The aim of the study was to assess the dietary protein requirement of healthy young male bodybuilders ( with ≥3 y training experience) on a nontraining day by measuring the oxidation of ingested l-[1-13C]phenylalanine to 13CO2 in response to graded intakes of protein [indicator amino acid oxidation (IAAO) technique].Methods: Eight men (means ± SDs: age, 22.5 ± 1.7 y; weight, 83.9 ± 11.6 kg; 13.0% ± 6.3% body fat) were studied at rest on a nontraining day, on several occasions (4-8 times) each with protein intakes ranging from 0.1 to 3.5 g · kg-1 · d-1, for a total of 42 experiments. The diets provided energy at 1.5 times each individual's measured resting energy expenditure and were isoenergetic across all treatments. Protein was fed as an amino acid mixture based on the protein pattern in egg, except for phenylalanine and tyrosine, which were maintained at constant amounts across all protein intakes. For 2 d before the study, all participants consumed 1.5 g protein · kg-1 · d-1 On the study day, the protein requirement was determined by identifying the breakpoint in the F13CO2 with graded amounts of dietary protein [mixed-effects change-point regression analysis of F13CO2 (labeled tracer oxidation in breath)].Results: The Estimated Average Requirement (EAR) of protein and the upper 95% CI RDA for these young male bodybuilders were 1.7 and 2.2 g · kg-1 · d-1, respectively.Conclusion: These IAAO data suggest that the protein EAR and recommended intake for male bodybuilders at rest on a nontraining day exceed the current recommendations of the Institute of Medicine by ∼2.6-fold. This trial was registered at clinicaltrials.gov as NCT02621294.","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86762559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
Dietary Protein Intake in Young Children in Selected Low-Income Countries Is Generally Adequate in Relation to Estimated Requirements for Healthy Children, Except When Complementary Food Intake Is Low. 部分低收入国家幼儿的膳食蛋白质摄入量与健康儿童的估计需求量相比基本充足,但辅助食品摄入量较低时除外。
The Journal of Nutrition Health and Aging Pub Date : 2017-05-01 Epub Date: 2017-02-15 DOI: 10.3945/jn.116.239657
Joanne E Arsenault, Kenneth H Brown
{"title":"Dietary Protein Intake in Young Children in Selected Low-Income Countries Is Generally Adequate in Relation to Estimated Requirements for Healthy Children, Except When Complementary Food Intake Is Low.","authors":"Joanne E Arsenault, Kenneth H Brown","doi":"10.3945/jn.116.239657","DOIUrl":"10.3945/jn.116.239657","url":null,"abstract":"<p><p><b>Background:</b> Previous research indicates that young children in low-income countries (LICs) generally consume greater amounts of protein than published estimates of protein requirements, but this research did not account for protein quality based on the mix of amino acids and the digestibility of ingested protein.<b>Objective:</b> Our objective was to estimate the prevalence of inadequate protein and amino acid intake by young children in LICs, accounting for protein quality.<b>Methods:</b> Seven data sets with information on dietary intake for children (6-35 mo of age) from 6 LICs (Peru, Guatemala, Ecuador, Bangladesh, Uganda, and Zambia) were reanalyzed to estimate protein and amino acid intake and assess adequacy. The protein digestibility-corrected amino acid score of each child's diet was calculated and multiplied by the original (crude) protein intake to obtain an estimate of available protein intake. Distributions of usual intake were obtained to estimate the prevalence of inadequate protein and amino acid intake for each cohort according to Estimated Average Requirements.<b>Results:</b> The prevalence of inadequate protein intake was highest in breastfeeding children aged 6-8 mo: 24% of Bangladeshi and 16% of Peruvian children. With the exception of Bangladesh, the prevalence of inadequate available protein intake decreased by age 9-12 mo and was very low in all sites (0-2%) after 12 mo of age. Inadequate protein intake in children <12 mo of age was due primarily to low energy intake from complementary foods, not inadequate protein density.<b>Conclusions:</b> Overall, most children consumed protein amounts greater than requirements, except for the younger breastfeeding children, who were consuming low amounts of complementary foods. These findings reinforce previous evidence that dietary protein is not generally limiting for children in LICs compared with estimated requirements for healthy children, even after accounting for protein quality. However, unmeasured effects of infection and intestinal dysfunction on the children's protein requirements could modify this conclusion.</p>","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77135274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Greater Adherence to Cancer Prevention Guidelines Is Associated with Higher Circulating Concentrations of Vitamin D Metabolites in a Cross-Sectional Analysis of Pooled Participants from 2 Chemoprevention Trials. 对两项化学预防试验参与者的横断面分析表明,更严格地遵守癌症预防指南与更高的维生素D代谢物循环浓度相关。
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 DOI: 10.3945/jn.116.243352
L. Kohler, Elizabeth A Hibler, Robin B Harris, Eyal Oren, D. Roe, P. Jurutka, E. Jacobs
{"title":"Greater Adherence to Cancer Prevention Guidelines Is Associated with Higher Circulating Concentrations of Vitamin D Metabolites in a Cross-Sectional Analysis of Pooled Participants from 2 Chemoprevention Trials.","authors":"L. Kohler, Elizabeth A Hibler, Robin B Harris, Eyal Oren, D. Roe, P. Jurutka, E. Jacobs","doi":"10.3945/jn.116.243352","DOIUrl":"https://doi.org/10.3945/jn.116.243352","url":null,"abstract":"Background: Several lifestyle factors targeted by the American Cancer Society (ACS) Nutrition and Physical Activity Cancer Prevention Guidelines are also associated with circulating concentrations of vitamin D metabolites. This suggests that greater adherence to the ACS guidelines may be related to better vitamin D status.Objective: We examined the relation between adherence to the ACS guidelines and circulating concentrations of 2 vitamin D metabolites, 25-hydroxycholecalciferol [25(OH)D] and 1α,25-dihydroxyvitamin D [1,25(OH)2D].Methods: We conducted cross-sectional analyses of pooled participants from the Wheat Bran Fiber (n = 503) and Ursodeoxycholic Acid (n = 854) trials. A cumulative adherence score was constructed with the use of baseline data on body size, diet, physical activity, and alcohol consumption. Continuous vitamin D metabolite concentrations and clinically relevant categories were evaluated with the use of multiple linear and logistic regression models, respectively.Results: The most adherent participants were more likely to be older, white, and nonsmokers than were the least adherent. A statistically significant association was observed between guideline adherence and concentrations of circulating 25(OH)D (means ± SEs-high adherence: 32.0 ± 0.8 ng/mL; low adherence: 26.4 ± 0.7 ng/mL; P-trend < 0.001). For 1,25(OH)2D concentrations, high adherence was again significantly related to greater metabolite concentrations, with mean ± SE concentrations of 36.3 ± 1.3 pg/mL and 31.9 ± 1.0 pg/mL for high- and low-adherers, respectively (P-trend = 0.008). Furthermore, the odds of attaining a sufficient 25(OH)D status were 4.37 times higher for those most adherent than for those least adherent (95% CI: 2.47, 7.71 times).Conclusion: These findings demonstrate that greater adherence to the ACS guidelines is associated with higher circulating concentrations of both of 25(OH)D and 1,25(OH)2D.","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87624477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Sufficient Protein Quality of Food Aid Varies with the Physiologic Status of Recipients. 粮食援助的充足蛋白质质量因受援者的生理状况而异。
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 Epub Date: 2017-01-18 DOI: 10.3945/jn.116.239665
Meghan Callaghan, Momo Oyama, Mark Manary
{"title":"Sufficient Protein Quality of Food Aid Varies with the Physiologic Status of Recipients.","authors":"Meghan Callaghan, Momo Oyama, Mark Manary","doi":"10.3945/jn.116.239665","DOIUrl":"10.3945/jn.116.239665","url":null,"abstract":"<p><p>Protein quality scores use the amino acid (AA) requirements of a healthy North American child. AA requirements vary with physiologic status. We estimated AA requirements for healthy North American children, children with environmental enteric dysfunction, children recovering from wasting, and children with an acute infection. The protein quality of food aid products was then calculated to determine whether it was sufficient in all these groups, and we found that it may not be adequate for all of them. Physiologic status is important when assessing the protein quality of food aid. Rates of weight gain from 8 published trials treating children with moderate acute malnutrition were abstracted, and protein quality scores from the corresponding food aid products were calculated with the use of the digestible indispensable amino acid score (DIAAS). Two DIAAS values were calculated, one in healthy children aged 1-3 y as a reference population and the other in malnourished children aged 1-3 y as a reference population. These data were used to calculate the best fit regression line between weight gain and protein quality. The slope of the regression line was greater when malnourished children were used as a reference population than when healthy children were used (0.128; 95% CI: 0.118, 0.138 compared with 0.097; 95% CI: 0.090, 0.105 measured in g · kg<sup>-1</sup> · d<sup>-1</sup> · DIASS U<sup>-1</sup>). These findings suggest that adjusting AA requirements for physiologic status may more accurately estimate the minimum protein quality of food aid products.</p>","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86901985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increases in Plasma Tryptophan Are Inversely Associated with Incident Cardiovascular Disease in the Prevención con Dieta Mediterránea (PREDIMED) Study. Prevención con Dieta Mediterránea (PREDIMED) 研究中血浆色氨酸的增加与心血管疾病的发病率成反比。
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 Epub Date: 2017-02-08 DOI: 10.3945/jn.116.241711
Edward Yu, Miguel Ruiz-Canela, Marta Guasch-Ferré, Yan Zheng, Estefania Toledo, Clary B Clish, Jordi Salas-Salvadó, Liming Liang, Dong D Wang, Dolores Corella, Montse Fitó, Enrique Gómez-Gracia, José Lapetra, Ramón Estruch, Emilio Ros, Montserrat Cofán, Fernando Arós, Dora Romaguera, Lluis Serra-Majem, Jose V Sorlí, Frank B Hu, Miguel A Martinez-Gonzalez
{"title":"Increases in Plasma Tryptophan Are Inversely Associated with Incident Cardiovascular Disease in the Prevención con Dieta Mediterránea (PREDIMED) Study.","authors":"Edward Yu, Miguel Ruiz-Canela, Marta Guasch-Ferré, Yan Zheng, Estefania Toledo, Clary B Clish, Jordi Salas-Salvadó, Liming Liang, Dong D Wang, Dolores Corella, Montse Fitó, Enrique Gómez-Gracia, José Lapetra, Ramón Estruch, Emilio Ros, Montserrat Cofán, Fernando Arós, Dora Romaguera, Lluis Serra-Majem, Jose V Sorlí, Frank B Hu, Miguel A Martinez-Gonzalez","doi":"10.3945/jn.116.241711","DOIUrl":"10.3945/jn.116.241711","url":null,"abstract":"<p><p><b>Background:</b> During development of cardiovascular disease (CVD), interferon-γ-mediated inflammation accelerates degradation of tryptophan into downstream metabolites. A Mediterranean diet (MedDiet) consisting of a high intake of extra-virgin olive oil (EVOO), nuts, fruits, vegetables, and cereals has been demonstrated to lower the risk of CVD. The longitudinal relation between tryptophan and its downstream metabolites and CVD in the context of a MedDiet is unstudied.<b>Objective:</b> We sought to investigate the relation between metabolites in the tryptophan-kynurenine pathway and CVD in the context of a MedDiet pattern.<b>Methods:</b> We used a case-cohort design nested in the Prevención con Dieta Mediterránea randomized controlled trial. There were 231 CVD cases (stroke, myocardial infarction, cardiovascular death) among 985 participants over a median of 4.7 y of follow-up [mean ± SD age: 67.6 ± 6.1 y; 53.7% women; mean ± SD body mass index (in kg/m<sup>2</sup>): 29.7 ± 3.7]. We assessed plasma tryptophan, kynurenine, kynurenic acid, 3-hydroxyanthranilic acid, and quinolinic acid concentrations at baseline and after 1 y of intervention with a MedDiet. We combined these metabolites in a kynurenine risk score (KRS) by weighting each metabolite by the adjusted coefficient of its associations with CVD. Cox models were used in the primary analysis.<b>Results:</b> Increases in tryptophan after 1 y were associated with a lower risk of composite CVD (HR per SD: 0.79; 95% CI: 0.63, 0.98). The baseline kynurenic acid concentration was associated with a higher risk of myocardial infarction and coronary artery disease death but not stroke. A higher KRS was more strongly associated with CVD in the control group than in the 2 intervention groups (<i>P</i>-interaction = 0.003). Adjustment for changes in plasma tryptophan attenuated the inverse association between MedDiet+EVOO and CVD.<b>Conclusions:</b> An increase in the plasma tryptophan concentration was significantly associated with a decreased risk of CVD. A MedDiet may counteract the deleterious effects of a high kynurenine risk score.</p>","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80593840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Protein and High-Dietary Fiber Breakfasts Result in Equal Feelings of Fullness and Better Diet Quality in Low-Income Preschoolers Compared with Their Usual Breakfast. 与普通早餐相比,高蛋白和高膳食纤维早餐能让低收入学龄前儿童产生同样的饱腹感,并提高他们的饮食质量。
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 Epub Date: 2017-01-11 DOI: 10.3945/jn.116.234153
Sibylle Kranz, Mary Brauchla, Wayne W Campbell, Rickard D Mattes, Amy J Schwichtenberg
{"title":"High-Protein and High-Dietary Fiber Breakfasts Result in Equal Feelings of Fullness and Better Diet Quality in Low-Income Preschoolers Compared with Their Usual Breakfast.","authors":"Sibylle Kranz, Mary Brauchla, Wayne W Campbell, Rickard D Mattes, Amy J Schwichtenberg","doi":"10.3945/jn.116.234153","DOIUrl":"10.3945/jn.116.234153","url":null,"abstract":"<p><p><b>Background:</b> In the United States, 17% of children are currently obese. Increasing feelings of fullness may prevent excessive energy intake, lead to better diet quality, and promote long-term maintenance of healthy weight.<b>Objective:</b> The purpose of this study was to develop a fullness-rating tool (aim 1) and to determine whether a high-protein (HP), high-fiber (HF), and combined HP and HF (HPHF) breakfast increases preschoolers' feelings of fullness before (pre) and after (post) breakfast and pre-lunch, as well as their diet quality, as measured by using a composite diet quality assessment tool, the Revised Children's Diet Quality Index (aim 2).<b>Methods:</b> Children aged 4 and 5 y (<i>n</i> = 41; 22 girls and 19 boys) from local Head Start centers participated in this randomized intervention trial. Sixteen percent of boys and 32% of girls were overweight or obese. After the baseline week, children rotated through four 1-wk periods of consuming ad libitum HP (19-20 g protein), HF (10-11 g fiber), HPHF (19-21 g protein, 10-12 g fiber), or usual (control) breakfasts. Food intake at breakfast was estimated daily, and for breakfast, lunch, and snack on day 3 of each study week Student's <i>t</i> tests and ANOVA were used to determine statistical differences.<b>Results:</b> Children's post-breakfast and pre-lunch fullness ratings were ≥1 point higher than those of pre-breakfast (aim 1). Although children consumed, on average, 65 kcal less energy during the intervention breakfasts (<i>P</i> < 0.007) than during the control breakfast, fullness ratings did not differ (<i>P</i> = 0.76). Relative to the control breakfast, improved diet quality (12%) was calculated for the HP and HF breakfasts (<i>P</i> < 0.027) but not for the HPHF breakfast (aim 2).<b>Conclusions:</b> Post-breakfast fullness ratings were not affected by the intervention breakfasts relative to the control breakfast. HP and HF breakfasts resulted in higher diet quality. Serving HP or HF breakfasts may be valuable in improving diet quality without lowering feelings of satiation or satiety. This trial was registered at clinicaltrials.gov as NCT02122224.</p>","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85580738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intake of up to 3 Eggs per Day Is Associated with Changes in HDL Function and Increased Plasma Antioxidants in Healthy, Young Adults. 在健康的年轻人中,每天摄入3个鸡蛋与高密度脂蛋白功能的变化和血浆抗氧化剂的增加有关。
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 DOI: 10.3945/jn.116.241877
Diana M. DiMarco, Gregory H. Norris, Courtney L Millar, C. Blesso, M. Fernández
{"title":"Intake of up to 3 Eggs per Day Is Associated with Changes in HDL Function and Increased Plasma Antioxidants in Healthy, Young Adults.","authors":"Diana M. DiMarco, Gregory H. Norris, Courtney L Millar, C. Blesso, M. Fernández","doi":"10.3945/jn.116.241877","DOIUrl":"https://doi.org/10.3945/jn.116.241877","url":null,"abstract":"Background: HDL function may be more important than HDL concentration in determining risk for cardiovascular disease. In addition, HDL is a carrier of carotenoids and antioxidant enzymes, which protect HDL and LDL particles against oxidation.Objective: The goal of this study was to determine the impact of consuming 0-3 eggs/d on LDL and HDL particle size, HDL function, and plasma antioxidants in a young, healthy population.Methods: Thirty-eight healthy men and women [age 18-30 y, body mass index (in kg/m2) 18.5-29.9] participated in this 14-wk crossover intervention. Subjects underwent a 2-wk washout (0 eggs/d) followed by sequentially increasing intake of 1, 2, and 3 eggs/d for 4 wk each. After each period, fasting blood was collected for analysis of lipoprotein subfractions, plasma apolipoprotein (apo) concentration, lutein and zeaxanthin concentration, and activities of lecithin-cholesterol acyltransferase, cholesteryl ester transfer protein, and paraoxonase-1.Results: Compared with intake of 0 eggs/d, consuming 1-3 eggs/d resulted in increased large-LDL (21-37%) and large-HDL (6-13%) particle concentrations, plasma apoAI (9-15%), and lecithin-cholesterol acyltransferase activity (5-15%) (P < 0.05 for all biomarkers). Intake of 2-3 eggs/d also promoted an 11% increase in apoAII (P < 0.05) and a 20-31% increase in plasma lutein and zeaxanthin (P < 0.05), whereas intake of 3 eggs/d resulted in a 9-16% increase in serum paraoxonase-1 activity compared with intake of 1-2 eggs/d (P < 0.05). Egg intake did not affect cholesteryl ester transfer protein activity.Conclusions: Intake of 1 egg/d was sufficient to increase HDL function and large-LDL particle concentration; however, intake of 2-3 eggs/d supported greater improvements in HDL function as well as increased plasma carotenoids. Overall, intake of ≤3 eggs/d favored a less atherogenic LDL particle profile, improved HDL function, and increased plasma antioxidants in young, healthy adults. This trial was registered at clinicaltrials.gov as NCT02531958.","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88107312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 51
A Systematic Review of the Effects of Plant Compared with Animal Protein Sources on Features of Metabolic Syndrome. 植物与动物蛋白质来源对代谢综合征特征影响的系统综述。
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 DOI: 10.3945/jn.116.239574
T. Chalvon-Demersay, D. Azzout-Marniche, Judith Arfsten, L. Egli, C. Gaudichon, L. Karagounis, D. Tomé
{"title":"A Systematic Review of the Effects of Plant Compared with Animal Protein Sources on Features of Metabolic Syndrome.","authors":"T. Chalvon-Demersay, D. Azzout-Marniche, Judith Arfsten, L. Egli, C. Gaudichon, L. Karagounis, D. Tomé","doi":"10.3945/jn.116.239574","DOIUrl":"https://doi.org/10.3945/jn.116.239574","url":null,"abstract":"Dietary protein may play an important role in the prevention of metabolic dysfunctions. However, the way in which the protein source affects these dysfunctions has not been clearly established. The aim of the current systematic review was to compare the impact of plant- and animal-sourced dietary proteins on several features of metabolic syndrome in humans. The PubMed database was searched for both chronic and acute interventional studies, as well as observational studies, in healthy humans or those with metabolic dysfunctions, in which the impact of animal and plant protein intake was compared while using the following variables: cholesterolemia and triglyceridemia, blood pressure, glucose homeostasis, and body composition. Based on data extraction, we observed that soy protein consumption (with isoflavones), but not soy protein alone (without isoflavones) or other plant proteins (pea and lupine proteins, wheat gluten), leads to a 3% greater decrease in both total and LDL cholesterol compared with animal-sourced protein ingestion, especially in individuals with high fasting cholesterol concentrations. This observation was made when animal proteins were provided as a whole diet rather than given supplementally. Some observational studies reported an inverse association between plant protein intake and systolic and diastolic blood pressure, but this was not confirmed by intervention studies. Moreover, plant protein (wheat gluten, soy protein) intake as part of a mixed meal resulted in a lower postprandial insulin response than did whey. This systematic review provides some evidence that the intake of soy protein associated with isoflavones may prevent the onset of risk factors associated with cardiovascular disease, i.e., hypercholesterolemia and hypertension, in humans. However, we were not able to draw any further conclusions from the present work on the positive effects of plant proteins relating to glucose homeostasis and body composition.","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73108337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 87
Breakfast Dietary Patterns among Mexican Children Are Related to Total-Day Diet Quality. 墨西哥儿童的早餐饮食模式与全天饮食质量有关
The Journal of Nutrition Health and Aging Pub Date : 2017-03-01 DOI: 10.3945/jn.116.239780
M. Afeiche, L. Taillie, S. Hopkins, A. Eldridge, B. Popkin
{"title":"Breakfast Dietary Patterns among Mexican Children Are Related to Total-Day Diet Quality.","authors":"M. Afeiche, L. Taillie, S. Hopkins, A. Eldridge, B. Popkin","doi":"10.3945/jn.116.239780","DOIUrl":"https://doi.org/10.3945/jn.116.239780","url":null,"abstract":"Background: Mexico has experienced shifts in food availability and consumption patterns over the past few decades from traditional diets to those containing more high-energy density foods, resulting in the development of unhealthful dietary patterns among children and adults. However, to our knowledge it is not known whether breakfast consumption patterns contribute to the overall daily diet of Mexican children.Objective: We examined total-day diet among breakfast consumers compared with breakfast skippers, identified and investigated breakfast dietary patterns in relation to energy and nutrient intakes at breakfast and across the day, and examined these patterns in relation to sociodemographic characteristics.Methods: With the use of nationally representative dietary data (one 24-h recall) from the 2012 Mexican National Health and Nutrition Survey, 3760 children aged 4-13 y were categorized into mutually exclusive breakfast patterns with the use of cluster analysis. The association between breakfast patterns and breakfast skippers with dietary intake at breakfast and for the total day was investigated with the use of multivariate linear regression.Results: Most children (83%) consumed breakfast. Six breakfast dietary patterns were identified (milk and sweetened breads, tortillas and beans, sweetened beverages, sandwiches and quesadillas, eggs, and cereal and milk) and reflected both traditional and more Westernized dietary patterns. Sugar-sweetened beverages were consumed across all patterns. Compared with all breakfast dietary patterns, breakfast skippers had the lowest intake of several nutrients of public health concern. Nutrients to limit that were high at breakfast tended to be high for the total day and vice versa for nutrients to encourage.Conclusions: There was not a single pattern that complied perfectly with the Mexican School Breakfast Guidelines, but changes such as increasing dietary fiber by encouraging more whole grains, fruits, vegetables, and beans and reducing sodium and sugar-sweetened beverages could support compliance with these targets and improve overall diet quality.","PeriodicalId":22788,"journal":{"name":"The Journal of Nutrition Health and Aging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88857861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 58
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