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The journal of Japan Atherosclerosis Society最新文献

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Postprandial hyperlipidemia and atherosclerosis-An overview- 餐后高脂血症与动脉粥样硬化-综述
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.9-10_357
Y. Maruhama
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引用次数: 0
Visceral fat syndrome and insulin resistance 内脏脂肪综合征和胰岛素抵抗
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.11-12_403
Tadashi Nakamura, T. Funahashi, Y. Matsuzawa
{"title":"Visceral fat syndrome and insulin resistance","authors":"Tadashi Nakamura, T. Funahashi, Y. Matsuzawa","doi":"10.5551/JAT1973.25.11-12_403","DOIUrl":"https://doi.org/10.5551/JAT1973.25.11-12_403","url":null,"abstract":"近年の食生活やライフスタイルの変化により, わが国に おいても冠動脈疾患をはじめとする動脈硬化性疾患が増加 しており, 大きな問題 となっている. この過栄養状態を基 盤 とし動脈硬化性疾患を高率に発症する病態は, 耐糖能異 常や高脂血症, 高血圧などの多数の危険因子が同時に集簇 して存在することが特徴であり, Table 1に示すような種々 の概念が提唱 されてい る.そ の代表 として1988年 に Reavenが 提唱した 「シンドロームX (Syndrome X)」 は主 として非肥満者を対象 としたものであり, 肥満が動脈硬化 に寄与する病態としては,翌 年Kaplanの 提唱 した「死の四 重奏(The deadly quaaret)」があげられる1,2). これら概念の 根底には, 肥満の有無にかかわらず,い ずれもインスリン 抵抗性の存在を推察 してお り, 同様の概念 としてインスリ ン抵抗性をこれら概念の中心的な因子 として重要視する考 え方から, 1991年 にDeFronzoら が 「インス リン抵抗性症 候群(Syndrome of insulin resistance)」なる呼称を用いるに 至った3). このことにより, 糖尿病研究者だけでなく, 循環 器の分野で もインス リン抵抗性 ということばが注目され, 関心が高まるようになった. しかし, これら病態に認めら れるインスリン抵抗性の発症機序の本態は何か, また, こ れら概念ではインスリン抵抗性により生じる高インスリン 血症が重要視されているが,は た してそれは正 しいのか, さらに, 集簇する多数の危険因子をインス リン抵抗性のみ で説明しうるか否かに関して, いまだ明確な考え方は示さ れていない. , 肥満における脂肪分布 と合併症の研究において, 上半身肥満 といった皮下脂肪の分布ではな く, 内臓の脂肪 蓄積に着目した著者らの検討により, 腹腔内(主 に腸間膜) に脂肪が蓄積する 「内臓脂肪型肥満(Visceral fat obesity)」 が密接にインス リン抵抗性 と関連して種々の危険因子を発 症 し動脈硬化につながることが明らかとなっている45). し たがって, 内臓脂肪型肥満は前述した種々の概念 と共通す る病態である. さらに, 最近になって, この内臓脂肪の蓄 積が肥満者だけでな く, 正常体重者においても耐糖能異常 をはじめ種々の危険因子, ひいては動脈硬化性疾患の発症 と強 く関係することを明らかにし, 普遍的に動脈硬化の成 立に関与する病態として 「内臓脂肪症候群(Visceral fat syndrome)」 なる概念 を提唱 している6).本症候群 はRisk factors clusteringの成立機構 の上流に内臓脂肪蓄積を置き, インスリン抵抗性を含めた種々の因子が存在 し, 最終的に 動脈硬化 を発症するメカニズムを想定 している. 本稿で は,マ ルチプル リスクファクター症候群におけるインス リ ン抵抗性の位置づけ, および内臓脂肪蓄積の意義につき述 べる.","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80058858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arterial thrombus Formation and von Willebrand factordependent platelet aggregation. 动脉血栓形成和血管性血友病因子依赖性血小板聚集。
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.6-7_237
K. Kawano, M. Murata
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引用次数: 0
Plaque rupture and intimal neovascularization 斑块破裂和内膜新生血管
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.6-7_263
Y. Nakashima, M. Kumamoto, Yong-Xiang Chen, K. Sueishi
{"title":"Plaque rupture and intimal neovascularization","authors":"Y. Nakashima, M. Kumamoto, Yong-Xiang Chen, K. Sueishi","doi":"10.5551/JAT1973.25.6-7_263","DOIUrl":"https://doi.org/10.5551/JAT1973.25.6-7_263","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74112073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of the renin-angiotensin system in plaque rupture of coronary artery 肾素-血管紧张素系统在冠状动脉斑块破裂中的作用
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.6-7_269
M. Ohishi, M. Ueda, T. Naruko, A. Kojima, A. Okamura, H. Rakugi, J. Higaki, T. Ogihara
{"title":"The role of the renin-angiotensin system in plaque rupture of coronary artery","authors":"M. Ohishi, M. Ueda, T. Naruko, A. Kojima, A. Okamura, H. Rakugi, J. Higaki, T. Ogihara","doi":"10.5551/JAT1973.25.6-7_269","DOIUrl":"https://doi.org/10.5551/JAT1973.25.6-7_269","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74651183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of niceritrol and pravastatin combination therapy for hyperlipidemia 硝酸甘油与普伐他汀联合治疗高脂血症的疗效评价
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.26.3_95
M. Kinoshita, Hiroaki Suzuki, T. Matsushima, T. Teramoto
{"title":"Evaluation of niceritrol and pravastatin combination therapy for hyperlipidemia","authors":"M. Kinoshita, Hiroaki Suzuki, T. Matsushima, T. Teramoto","doi":"10.5551/JAT1973.26.3_95","DOIUrl":"https://doi.org/10.5551/JAT1973.26.3_95","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74808187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Rupture of Atherosclerotic Plaque 动脉粥样硬化斑块破裂
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.6-7_243
S. Katsuda, M. Mitsumata
{"title":"Rupture of Atherosclerotic Plaque","authors":"S. Katsuda, M. Mitsumata","doi":"10.5551/JAT1973.25.6-7_243","DOIUrl":"https://doi.org/10.5551/JAT1973.25.6-7_243","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76460884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
マクロファージ・リンパ球と動脈硬化の進展-特に接着蛋白ICAM-1/LFA-1とMMP-12の関わり- 巨噬细胞和动脉硬化的进展，特别是粘附蛋白ICAM-1/LFA-1和mpf -12的关系。
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/jat1973.26.4-5_173
渡辺 照男, 范 江霖, 松本 俊一郎, 小林 達伺
{"title":"マクロファージ・リンパ球と動脈硬化の進展-特に接着蛋白ICAM-1/LFA-1とMMP-12の関わり-","authors":"渡辺 照男, 范 江霖, 松本 俊一郎, 小林 達伺","doi":"10.5551/jat1973.26.4-5_173","DOIUrl":"https://doi.org/10.5551/jat1973.26.4-5_173","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82969812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular endothelial growth factor expression in the atherosclerotic lesion 血管内皮生长因子在动脉粥样硬化病变中的表达
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.25.8_289
M. Kuroki
{"title":"Vascular endothelial growth factor expression in the atherosclerotic lesion","authors":"M. Kuroki","doi":"10.5551/JAT1973.25.8_289","DOIUrl":"https://doi.org/10.5551/JAT1973.25.8_289","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77532138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Modified structures and metabolism of oxidized LDL 修饰的结构和氧化LDL的代谢
The journal of Japan Atherosclerosis Society Pub Date : 1998-01-01 DOI: 10.5551/JAT1973.26.1_17
H. Itabe, T. Takano
{"title":"Modified structures and metabolism of oxidized LDL","authors":"H. Itabe, T. Takano","doi":"10.5551/JAT1973.26.1_17","DOIUrl":"https://doi.org/10.5551/JAT1973.26.1_17","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88917551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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