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The MAK-Collection for Occupational Health and Safety最新文献

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Ethylenoxid [MAK value documentation in German language, 2019] 环氧乙烷[德语MAK值文档，2019年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb7521d0034
A. Hartwig, M. Arand
{"title":"Ethylenoxid [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb7521d0034","DOIUrl":"https://doi.org/10.1002/3527600418.mb7521d0034","url":null,"abstract":"Das krebserzeugende Potential von Ethylenoxid wurde erstmals 1984 beurteilt. Ethylenoxid ist ein alkylierendes Agens und reagiert mit Hydroxyl-, Sulfhydryl-, Aminound Carboxylgruppen von Makromolekülen. Vergiftungen bei akuten Expositionsbedingungen sind durch lokale Reizungen auf Haut und Schleimhaut und durch systemische Wirkungen auf ZNS, Herz und andere Organe gekennzeichnet. Systemische Wirkungen werden auch infolge ausschließlich resorptiver Aufnahme über die Haut hervorgerufen. Deswegen ist Ethylenoxid seit 1984 mit „H“ markiert. Ethylenoxid erwies sich in vitro und in vivo als mutagen. Ethylenoxid besitzt im Tierexperiment ein eindeutig krebserzeugendes Potential und ist seit 1984 in die Kategorie 2 für krebserzeugende Stoffe der MAKund BAT-Werte-Liste eingestuft. Für Ethylenoxid liegt eine Dokumentation einer Korrelation von Stoffkonzentration in der Luft am Arbeitsplatz zur Stoffbzw. Metabolitenkonzentration im biologischen Material vor (EKA; Greim und Lehnert 2001).","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"273 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79978066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zirkonium und seine Verbindungen (außer Zirkoniumdioxid) [MAK value documentation in German language, 2019] 升起的时候。
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb744067verd0067
A. Hartwig, Michael Arand
{"title":"Zirkonium und seine Verbindungen (außer Zirkoniumdioxid) [MAK value documentation in German language, 2019]","authors":"A. Hartwig, Michael Arand","doi":"10.1002/3527600418.mb744067verd0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb744067verd0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87292039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methylformiat (Ameisensäuremethylester) [MAK value documentation in German language, 2019] 甲脒(Ameisensäuremethylester)[德语MAK值文档，2019年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb10731d0067
A. Hartwig, Michael Arand
{"title":"Methylformiat (Ameisensäuremethylester) [MAK value documentation in German language, 2019]","authors":"A. Hartwig, Michael Arand","doi":"10.1002/3527600418.mb10731d0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb10731d0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90509402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methanol [MAK value documentation in German language, 2019] 甲醇[2019年德语MAK值文件]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb6756d0067
A. Hartwig, M. Arand
{"title":"Methanol [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb6756d0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb6756d0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83816223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ethanthiol [MAK value documentation in German language, 2019] 乙醇[德语MAK值文件，2019年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb7508d0067
A. Hartwig, M. Arand
{"title":"Ethanthiol [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb7508d0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb7508d0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78944269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxalsäuredinitril [MAK value documentation in German language, 2019] Oxalsäuredinitril[德语MAK值文档，2019]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb46019d0067
A. Hartwig, M. Arand
{"title":"Oxalsäuredinitril [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb46019d0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb46019d0067","url":null,"abstract":"German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the workplace (MAK value) and the Pregnancy Risk Group of oxalonitrile [460‐19‐5]. \u0000There are no new data. The MAK value of 5 ml/m3 was determined in analogy to the more toxic metabolite hydrogen cyanide. The MAK value for hydrogen cyanide of 1.9 ml/m3 was derived from the human detoxification capacity per kg body weight with a respiratory volume of 10 m3. Therefore, the increased respiratory volume at the workplace has already been accounted for. The MAK value of oxalonitrile, which was set at 5 ml/m3 to reflect the 2.5‐fold higher acute toxicity of hydrogen cyanide, can be retained. This is also the case for Peak Limitation Category II and the excursion factor of 2 because no irritation was observed in humans below 16 ml/m3. \u0000There are no developmental toxicity studies. Therefore, oxalonitrile is assigned to Pregnancy Risk Group D.","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88178522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Zirkoniumdioxid (alveolengängige Fraktion) [MAK value documentation in German language, 2019] 二氧化锆(alveolengängige馏分)[德语MAK值文档，2019]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb131423d0067
A. Hartwig
{"title":"Zirkoniumdioxid (alveolengängige Fraktion) [MAK value documentation in German language, 2019]","authors":"A. Hartwig","doi":"10.1002/3527600418.mb131423d0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb131423d0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88287284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lindan [MAK value documentation in German language, 2019] Lindan[德语MAK值文档，2019]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb5889d0035
A. Hartwig, M. Arand
{"title":"Lindan [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb5889d0035","DOIUrl":"https://doi.org/10.1002/3527600418.mb5889d0035","url":null,"abstract":"Lindan wurde 1998 in die Kategorie 4 für krebserzeugende Arbeitsstoffe eingestuft. Nach den damals gültigen Kriterien war eine Einstufung in eine Kategorie für erbgutverändernde Arbeitsstoffe nicht erforderlich. Da mittlerweile neue Kriterien für die Einstufung von Stoffen in Kategorien für Keimzellmutagene erarbeitet wurden (vgl. Begründung „Keimzellmutagene“ 2000 unter „Allgemeines“), beschäftigt sich der vorliegende Nachtrag mit einer Bewertung der Daten zur Genotoxizität und Mutagenität von Lindan im Hinblick auf die neu definierten Einstufungskriterien. Im Zuge der Überarbeitung der Kurzzeitwert-Kategorien erfolgt eine Überprüfung der Spitzenbegrenzung.","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72953013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isobornylacrylat [MAK value documentation in German language, 2019] 异硼酸酯[德语MAK值文档，2019年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb588833d0067
A. Hartwig, M. Arand
{"title":"Isobornylacrylat [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb588833d0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb588833d0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83679685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aluminiumsilikatfasern (Refractory Ceramic Fibres, RCF) [MAK value documentation in German language, 2019] 硅酸铝(耐火陶瓷纤维，RCF)[德语MAK值文件，2019年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-08-01 DOI: 10.1002/3527600418.mb0234fasd0067
A. Hartwig, M. Arand
{"title":"Aluminiumsilikatfasern (Refractory Ceramic Fibres, RCF) [MAK value documentation in German language, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb0234fasd0067","DOIUrl":"https://doi.org/10.1002/3527600418.mb0234fasd0067","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90842159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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