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The MAK-Collection for Occupational Health and Safety最新文献

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Di‐ tert ‐dodecyl pentasulfide /Di‐ tert ‐dodecyl polysulfide [MAK value documentation, 2018] 二叔十二基五硫醚/二叔十二基聚硫醚[MAK值文件，2018]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb3156523kse6519
A. Hartwig
{"title":"Di‐\u0000 tert\u0000 ‐dodecyl pentasulfide /Di‐\u0000 tert\u0000 ‐dodecyl polysulfide [MAK value documentation, 2018]","authors":"A. Hartwig","doi":"10.1002/3527600418.mb3156523kse6519","DOIUrl":"https://doi.org/10.1002/3527600418.mb3156523kse6519","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88365170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibrous Dusts, inorganic [MAK value documentation, 2017] 无机纤维粉尘[MAK值文件，2017]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb0243fase6519
A. Hartwig
{"title":"Fibrous Dusts, inorganic [MAK value documentation, 2017]","authors":"A. Hartwig","doi":"10.1002/3527600418.mb0243fase6519","DOIUrl":"https://doi.org/10.1002/3527600418.mb0243fase6519","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86887710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isopropyl alcohol [MAK Value Documentation, 2018] 异丙醇[MAK值文件，2018]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb6763e6419
A. Hartwig, M. Arand
{"title":"Isopropyl alcohol [MAK Value Documentation, 2018]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb6763e6419","DOIUrl":"https://doi.org/10.1002/3527600418.mb6763e6419","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72877637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethylamine [MAK Value Documentation, 2019] 乙胺[MAK值文件，2019]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb7504e6619
A. Hartwig, M. Arand
{"title":"Ethylamine [MAK Value Documentation, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb7504e6619","DOIUrl":"https://doi.org/10.1002/3527600418.mb7504e6619","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86695746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
1,4‐Dichlorobenzene [MAK Value Documentation, 2018] 1,4‐二氯苯[MAK值文件，2018]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb10646e6519
A. Hartwig, M. Arand
{"title":"1,4‐Dichlorobenzene [MAK Value Documentation, 2018]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb10646e6519","DOIUrl":"https://doi.org/10.1002/3527600418.mb10646e6519","url":null,"abstract":"The German Commission for the investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated 1,4‐dichlorobenzene [106‐46‐7] considering all toxicological endpoints. Available publications and unpublished study reports are described in detail. \u0000 \u0000In mouse liver, 1,4‐dichlorobenzene causes carcinoma after oral and inhalation exposure and is mitogenic and cytotoxic. In reliable studies it is not genotoxic. As a non‐genotoxic mechanism is of prime importance and genotoxic effects play at most a minor part, provided the maximum concentration at the workplace (MAK value) is observed, 1,4‐dichlororbenzene is now classified in Category 4 for carcinogenic substances. \u0000 \u0000The chronic local NOAEC of 20 ml/m3 for changes in the olfactory epithelium of the rat nose would correspond to a MAK value of 10 ml/m3. However, the most sensitive toxicological effect is hepatocellular hypertrophy with a LOAEL of 10 mg/kg body weight and day in an oral 52‐week study with dogs. Because of the low severity and incidence of the effect, a NAEL (no adverse effect level) of 5 mg/kg body weight and day is assumed. This NAEL is scaled to a MAK value of 2 ml/m3. \u0000 \u0000Since a systemic effect is critical, Peak Limitation Category II is assigned. As it is not known if the effects are due to the metabolites or 1,4‐dichlorobenzene itself, the default excursion factor of 2 is assigned. \u0000 \u0000The NOAECs for developmental toxicity in rats and rabbits are 500 and 100 ml/m3, respectively, and the differences to the MAK value are sufficient. Therefore, damage to the embryo or foetus is unlikely when the MAK value is observed and 1,4‐dichlorobenzene is assigned to Pregnancy Risk Group C. Skin contact may contribute significantly to systemic toxicity and 1,4‐dichlorobenzene remains designated with an “H” notation. Sensitization is not expected from the limited data.","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88337036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tabakspezifische Nitrosamine – Bestimmung von N ‐Nitrosoanabasin, N ‐Nitrosoanatabin, N ‐Nitrosonornikotin und 4‐(Methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol in Urin mittels LC‐MS/MS [Biomonitoring methods in German language, 2019] Tabakspezifische Nitrosamine——确定N‐Nitrosoanabasin, N‐Nitrosoanatabin, N‐Nitrosonornikotin‐4‐(Methylnitrosamino) 1‐‐(pyridyl)‐1‐提取在尿液通过LC‐m / m [Biomonitoring methods在德国language, 2019年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.bi3762020d0022
G. Scherer, G. Gilch, D. Köhler, W. Völkel, T. Göen, A. Hartwig
{"title":"Tabakspezifische Nitrosamine – Bestimmung von\u0000 N\u0000 ‐Nitrosoanabasin,\u0000 N\u0000 ‐Nitrosoanatabin,\u0000 N\u0000 ‐Nitrosonornikotin und 4‐(Methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol in Urin mittels LC‐MS/MS [Biomonitoring methods in German language, 2019]","authors":"G. Scherer, G. Gilch, D. Köhler, W. Völkel, T. Göen, A. Hartwig","doi":"10.1002/3527600418.bi3762020d0022","DOIUrl":"https://doi.org/10.1002/3527600418.bi3762020d0022","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86615178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2,3,3,3‐Tetrafluoropropene [MAK Value Documentation, 2019] 2,3,3,3‐四氟丙烯[MAK值文件，2019]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb75412e6619
A. Hartwig, M. Arand
{"title":"2,3,3,3‐Tetrafluoropropene [MAK Value Documentation, 2019]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb75412e6619","DOIUrl":"https://doi.org/10.1002/3527600418.mb75412e6619","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76513649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addendum zu Lindan (γ‐1,2,3,4,5,6‐Hexachlorcyclohexan) [BAT value documentation in German language, 2019] 附录zu Lindan (γ‐1,2,3,4,5,6‐六氯环己烷)[德语BAT值文档，2019]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.bb5889d0024
B. Brinkmann, H. Drexler, A. Hartwig
{"title":"Addendum zu Lindan (γ‐1,2,3,4,5,6‐Hexachlorcyclohexan) [BAT value documentation in German language, 2019]","authors":"B. Brinkmann, H. Drexler, A. Hartwig","doi":"10.1002/3527600418.bb5889d0024","DOIUrl":"https://doi.org/10.1002/3527600418.bb5889d0024","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88872159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addendum zu Pentachlorphenol [BAT value documentation in German language, 2019] 五氯酚增编[2019年德文版本的BAT值文件]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.bb8786d0024
D. Walter, H. Drexler, A. Hartwig
{"title":"Addendum zu Pentachlorphenol [BAT value documentation in German language, 2019]","authors":"D. Walter, H. Drexler, A. Hartwig","doi":"10.1002/3527600418.bb8786d0024","DOIUrl":"https://doi.org/10.1002/3527600418.bb8786d0024","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87960717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chlorobenzene [MAK value documentation, 2018] 氯苯[MAK值文件，2018年]
The MAK-Collection for Occupational Health and Safety Pub Date : 2019-11-13 DOI: 10.1002/3527600418.mb10890e6519
A. Hartwig, M. Arand
{"title":"Chlorobenzene [MAK value documentation, 2018]","authors":"A. Hartwig, M. Arand","doi":"10.1002/3527600418.mb10890e6519","DOIUrl":"https://doi.org/10.1002/3527600418.mb10890e6519","url":null,"abstract":"","PeriodicalId":22742,"journal":{"name":"The MAK-Collection for Occupational Health and Safety","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74119361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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