The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi最新文献_第2页

Cystic Lymphangioma of Rectum-A Case Report and Review of Literature. 直肠囊性淋巴管瘤1例报告并文献复习。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-08-25 DOI: 10.4166/kjg.2023.057

Govindraj S Dessai, Nikhil Kumar Soni, Sharvari Pujari, Ramkrishna Prabhu, Chetan V Kantharia

引用次数: 0

[Calcium, Vitamin D, and Colorectal Cancer]. [钙、维生素D和结直肠癌]。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-08-25 DOI: 10.4166/kjg.2023.091

Young-Jo Wi, Soo-Young Na

引用次数: 0

Comparison of RDQ and GERDQ for Predicting Erosive Esophagitis in Patients with Typical GERD Symptoms. RDQ与GERDQ预测典型GERD症状患者糜烂性食管炎的比较

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-08-25 DOI: 10.4166/kjg.2023.027

Titong Sugihartono, Amal Arifi Hidayat, Michael Austin Pradipta Lusida, Kuntaman, Hafeza Aftab, Muhammad Miftahussurur

{"title":"Comparison of RDQ and GERDQ for Predicting Erosive Esophagitis in Patients with Typical GERD Symptoms.","authors":"Titong Sugihartono, Amal Arifi Hidayat, Michael Austin Pradipta Lusida, Kuntaman, Hafeza Aftab, Muhammad Miftahussurur","doi":"10.4166/kjg.2023.027","DOIUrl":"https://doi.org/10.4166/kjg.2023.027","url":null,"abstract":"Background/aims: The management decisions regarding gastroesophageal reflux disease (GERD) may differ according to the presence of erosive esophagitis. On the other hand, the availability of upper endoscopy in Indonesia is relatively limited. This study compared the Reflux Disease Questionnaire (RDQ) and the GERD questionnaire (GERDQ) performance in predicting the presence of clinically significant erosive esophagitis and determined the validity and reliability of the Indonesian-translated version of RDQ.Methods: Ninety-two adults with GERD suspicion were recruited. All patients completed RDQ and GERDQ. Receiver operating curve analysis was conducted on RDQ and GERDQ to evaluate their performance in discriminating LA GERD B or higher esophagitis from others. The translated RDQ preserved its main structure and was culturally adapted.Results: The patients were 66.3% female and 73.9% Javanese. Only 22 (23.9%) patients presented with LA grade B or higher erosive esophagitis. The RDQ showed a higher AUC than the GERDQ (0.602 vs. 0.589). A cutoff point of 20 was selected for the RDQ with sensitivity and specificity of 73% and 50%, respectively, whereas the optimal cutoff point of GERDQ was 8, with a sensitivity and specificity of 77% and 43%, respectively. The r-value greater than the critical value table (r>0.205, p<0.01) confirmed the construct validity of our translated RDQ. The questionnaire also demonstrated excellent reliability (α=0.900) and moderate similarity with the Indonesian version of GERDQ (κ=0.459, p<0.01).Conclusions: The RDQ is slightly superior to GERDQ in predicting the presence of clinically significant erosive esophagitis (LA grade B or higher). The Indonesian-translated RDQ is valid and reliable.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 2","pages":"84-90"},"PeriodicalIF":0.6,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Current Status and Prospects of Liquid Biopsy for Hepatocellular Carcinoma]. [肝细胞癌液体活检的现状与展望]。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-07-25 DOI: 10.4166/kjg.2023.076

Jumi Kang, Soon Sun Kim

{"title":"[Current Status and Prospects of Liquid Biopsy for Hepatocellular Carcinoma].","authors":"Jumi Kang, Soon Sun Kim","doi":"10.4166/kjg.2023.076","DOIUrl":"https://doi.org/10.4166/kjg.2023.076","url":null,"abstract":"Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally. Early detection and treatment response monitoring of HCC are vital for improved outcomes. Traditional diagnostic methods rely on imaging, serum tumor markers, and invasive liver tissue biopsy. The advent of liquid biopsy has revolutionized cancer diagnostics and management. Liquid biopsy involves the detection and analysis of tumor-derived components, such as circulating tumor DNA, circulating tumor cells, and extracellular vesicles, in various body fluids. These components reflect tumor characteristics, genetic alterations, and functional changes, providing valuable information for HCC diagnosis and treatment response monitoring. Liquid biopsy offers several advantages, including its non-invasive nature, potential for repetitive sampling, and real-time monitoring of disease progression and treatment response. However, challenges remain, including the sensitivity of detection methods, and standardization. In this review, we discuss the methods, current status, and prospects of liquid biopsy for HCC, highlighting its potential as a valuable tool in HCC management.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 1","pages":"1-9"},"PeriodicalIF":0.6,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9877549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity and Reliability of the Reflux Symptoms Index Translated into Indonesian: The Role of Upper Endoscopy in Assessing Extra-Esophageal Gastroesophageal Reflux Disease Symptoms. 反流症状指数翻译成印尼语的效度和信度:上内镜在评估食管外胃食管反流病症状中的作用

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-07-25 DOI: 10.4166/kjg.2023.029

Titong Sugihartono, Amal Arifi Hidayat, Michael Austin Pradipta Lusida, Kuntaman, Hafeza Aftab, Muhammad Miftahussurur

{"title":"Validity and Reliability of the Reflux Symptoms Index Translated into Indonesian: The Role of Upper Endoscopy in Assessing Extra-Esophageal Gastroesophageal Reflux Disease Symptoms.","authors":"Titong Sugihartono, Amal Arifi Hidayat, Michael Austin Pradipta Lusida, Kuntaman, Hafeza Aftab, Muhammad Miftahussurur","doi":"10.4166/kjg.2023.029","DOIUrl":"https://doi.org/10.4166/kjg.2023.029","url":null,"abstract":"Background/aims: The Reflux Symptom Index (RSI) is a questionnaire that evaluates the severity of extra-esophageal symptoms and is one of the most widely used measures to evaluate LPR. This study assessed the validity and reliability of the RSI questionnaire in Bahasa Indonesia and investigated the association between each extra-esophageal symptom reported in the questionnaire and the severity of erosive esophagitis as determined by endoscopic findings.Methods: 85 adult patients with GERD symptoms had an upper endoscopy examination and were asked to complete the translated RSI. The validity and reliability of the questionnaire were assessed.Results: The construct validity of the RSI translated into Bahasa Indonesia was verified with the r value of each question being higher than the crucial table value (r>0.213, p<0.05). Our questionnaire had a Cronbach alpha value of 0.81, which indicates an acceptable level of internal consistency. At least one extra-esophageal symptom was seen in 91.7% of patients with Los Angeles (LA) grade B or higher-grade esophagitis. In addition, the presence of extra-esophageal symptoms was associated with significant mucosal erosion (p=0.20). The symptoms of cough after eating or lying down and chronic cough were associated with the severity of esophageal mucosal erosion (p<0.05).Conclusions: The version of RSI translated into Bahasa Indonesia is a valid and reliable tool for assessing extra-esophageal GERD symptoms. The occurrence of extra-esophageal symptoms in patients with typical GERD symptoms is associated with endoscopic findings of LA grade B or erosive esophagitis of higher severity.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 1","pages":"18-24"},"PeriodicalIF":0.6,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9881712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunoglobulin G4-related Disease of the Small Bowel: A Case of Long-term Remission Achieved by Surgical Resection without Maintenance Therapy. 小肠免疫球蛋白G4相关疾病：一例无需维持治疗的手术切除远期缓解。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-07-25 DOI: 10.4166/kjg.2023.056

Seokin Kang, Yoon Suk Lee, Nam-Hoon Kim, Jun Hyuk Son, Jong Wook Kim, Mee Joo

{"title":"Immunoglobulin G4-related Disease of the Small Bowel: A Case of Long-term Remission Achieved by Surgical Resection without Maintenance Therapy.","authors":"Seokin Kang, Yoon Suk Lee, Nam-Hoon Kim, Jun Hyuk Son, Jong Wook Kim, Mee Joo","doi":"10.4166/kjg.2023.056","DOIUrl":"10.4166/kjg.2023.056","url":null,"abstract":"Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory disease. IgG4-RD can affect any organ system, including the pancreas, bile ducts, salivary glands, mesentery, and retroperitoneum. On the other hand, small intestine involvement is extremely rare. This paper describes a case of IgG4-RD involving the small bowel, particularly at the distal ileum. An 81-year-old female was admitted to the authors' hospital complaining of abdominal pain, dyspepsia, and hematochezia. The laboratory tests, including tumor markers and IgG4, were within normal limits. A colonoscopy did not show any abnormal findings. Abdominal computed tomography revealed segmental aneurysmal dilatation and wall thickening at the distal ileum, suggesting malignant conditions, such as small bowel lymphoma. The patient underwent an exploratory laparoscopy and ileocecectomy to differentiate a malignancy. A histopathology examination revealed dense lymphoplasmacytic infiltration, storiform fibrosis, and IgG4-positive plasma cells (>50 per high power field). The patient was finally diagnosed with IgG4-RD. The patient was followed up in the outpatient clinic for five years without recurrence. This paper suggests that a radical resection without maintenance therapy can be a treatment option, particularly when the IgG4-RD manifests as a localized gastrointestinal tract lesion.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 1","pages":"25-29"},"PeriodicalIF":0.6,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10242616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Transverse Myelitis Following Treatment with Atezolizumab for Advanced Hepatocellular Carcinoma. 阿替佐利珠单抗治疗晚期肝细胞癌后并发横贯性脊髓炎一例。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-07-25 DOI: 10.4166/kjg.2023.054

Kyung Han Kim, Yang-Hyun Baek, Yeo Wool Kang, Byeol-A Yoon, Sang Yi Moon

引用次数: 0

Phlebosclerotic Colitis in a Healthy Young Female with Long-term Herbal Medicine Use. 长期服用草药的健康年轻女性的静脉硬化性结肠炎。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-07-25 DOI: 10.4166/kjg.2023.058

Taehong Kim, Jin Lee, Ji Eun Na, Yong Eun Park, Jongha Park, Tae Oh Kim

引用次数: 0

Efficacy of 7-day Tailored Therapy for Helicobacter pylori Eradication based on Clarithromycin Resistance. 基于克拉霉素耐药的幽门螺杆菌7天定制治疗的疗效。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-07-25 DOI: 10.4166/kjg.2023.039

June Hwa Bae, Hyeong Ho Jo, Joong Goo Kwon, Eun Young Kim

{"title":"Efficacy of 7-day Tailored Therapy for Helicobacter pylori Eradication based on Clarithromycin Resistance.","authors":"June Hwa Bae, Hyeong Ho Jo, Joong Goo Kwon, Eun Young Kim","doi":"10.4166/kjg.2023.039","DOIUrl":"https://doi.org/10.4166/kjg.2023.039","url":null,"abstract":"Background/aims: Increasing resistance to clarithromycin (CAM) of Helicobacter pylori (H. pylori) is one of the main causes of recent decrease in eradication rate of standard triple therapy. The aim of this study was to evaluate the usefulness of 7-day tailored therapy based on the existence of CAM resistance.Methods: From January 2017 to May 2022, a total of 481 consecutive patients with H. pylori infection were recruited in Daegu Catholic University Medical Center. Treatment regimen was selected based on the result of CAM resistance test. Patients with CAM resistance (R group) were treated with bismuth-based quadruple therapy for 7 days. Patients without CAM resistance (S group) were treated with standard triple therapy for 7 days.Results: The overall H. pylori eradication rate was 89.4% (379 of 424) by per-protocol (PP) analysis. Patients with CAM resistance mutation included 166 patients (34.5%). The eradication rates of each group were 88.8% (135 of 152) and 89.7% (244 of 272) by PP analysis, for R and S group respectively. By intention-to-treat (ITT) analysis, the eradication rates were 81.3% (135 of 166) and 77.5% (244 of 315) for R and S group. CAM resistance was identified with a dual-priming oligonucleotide-based multiplex PCR.Conclusions: In spite of this high CAM resistance (34.5%), the eradication rate of 7-day tailored therapy based on the existence of CAM resistance was 89.4%. The 7-day tailored therapy based on CAM resistance could be an acceptable treatment selection strategy for H. pylori eradication.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 1","pages":"10-17"},"PeriodicalIF":0.6,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10257817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Five-year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction. 表现为胃出口梗阻的胃MALT淋巴瘤五年进展报告

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-06-25 DOI: 10.4166/kjg.2023.026

Hyundam Gu, Dae Young Cheung, Yeon Joo Seo, Eunjung Lee, Han Hee Lee, Jin Il Kim, Soo-Heon Park, Tae Jung Kim

{"title":"Five-year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction.","authors":"Hyundam Gu, Dae Young Cheung, Yeon Joo Seo, Eunjung Lee, Han Hee Lee, Jin Il Kim, Soo-Heon Park, Tae Jung Kim","doi":"10.4166/kjg.2023.026","DOIUrl":"10.4166/kjg.2023.026","url":null,"abstract":"This paper reports a 70-year-old female with gastric extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (gastric MALT lymphoma) as a rare case of gastric outlet obstruction. Five years earlier, she initially presented with weight loss and anemia. Esophagogastroduodenoscopy (EGD) revealed multiple gastric and duodenal ulcers with a pyloric deformity, while histology revealed chronic active inflammation and a Helicobacter pylori (H. pylori) infection. Three years earlier, she underwent EGD per the National Cancer Screening Program and was diagnosed with antral and duodenal ulcers. A forceps biopsy specimen from one of the ulcers showed the findings of gastric MALT lymphoma, but she did not visit the hospital for proper management. She visited complaining of a loss of appetite. EGD revealed a gastric outlet obstruction (GOO) caused by antral deformity and pyloric narrowing. A staged workup with CT and PET revealed full-layered, encircling antral wall thickening and several enlarged mesenteric lymph nodes. She was finally diagnosed with a gastric MALT lymphoma at Ann Arbor stage I1E with translocation t(11;18). She was treated with palliative surgery for GOO and systemic chemotherapy with a CHOP regimen. This paper reports a gastric MALT lymphoma that progressed from superficial mucosal lesions to an overt mass with regional lymph node metastasis for five years.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"81 6","pages":"265-269"},"PeriodicalIF":0.6,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10041714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0