The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi最新文献_第10页

[Paneth Cell Carcinoma of the Stomach]. [胃潘氏细胞癌]。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-07-25 DOI: 10.4166/kjg.2022.043

Jun Wan Kim, Gwang Ha Kim, Kyung Bin Kim

引用次数: 0

Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Hepatocellular Carcinoma Treated with Stereotactic Body Radiotherapy. 立体定向放射治疗肝癌中性粒细胞与淋巴细胞比值及血小板与淋巴细胞比值的研究。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-06-25 DOI: 10.4166/kjg.2022.021

Younghee Park, Ah Ram Chang

{"title":"Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Hepatocellular Carcinoma Treated with Stereotactic Body Radiotherapy.","authors":"Younghee Park, Ah Ram Chang","doi":"10.4166/kjg.2022.021","DOIUrl":"https://doi.org/10.4166/kjg.2022.021","url":null,"abstract":"Purpose: To investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with hepatocellular carcinoma (HCC) treated with stereotactic body radiotherapy (SBRT).Methods: The medical records of HCC patients treated with SBRT between 2008 and 2019 were reviewed retrospectively. The NLR and PLR were calculated from the serum complete blood count before and after SBRT, and the prognostic values of the NLR and PLR for the treatment outcomes were evaluated.Results: Thirty-nine patients with 49 HCC lesions were included. After a median follow-up of 26.8 months (range, 8.4-80.0 months), three-year local control, overall survival (OS), and progression-free survival (PFS) rate were 97.4%, 78.3%, and 35.2%, respectively. Both NLR and PLR increased significantly after SBRT and decreased slowly to the pre-SBRT value at 6 months. Univariable analysis showed that gross tumor volume (GTV) >14 cc, post-SBRT PLR >90, and PLR change >30 were associated with a poorer OS (p=0.002, p=0.011, and p=0.001, respectively), and the PLR change was significant in multivariable analysis (hazard ratio [HR], 10.09; 95% CI, 1.15-88.40; p=0.037). For PFS, GTV >14 cc, post-SBRT NLR >2.5 and post-SBRT PLR >90 were predictive of a poorer PFS in univariable analysis (p=0.011, p=0.004 and p=0.041, respectively) and only post-SBRT NLR >2.5 remained significant in multivariable analysis (HR, 2.44; 95% CI, 1.03-5.76; p=0.042, respectively).Conclusions: The NLR and PLR increased transiently after SBRT, and the post-SBRT NLR and PLR were associated with the clinical outcomes of HCC patients.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"79 6","pages":"252-259"},"PeriodicalIF":0.6,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40390253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Primary Biliary Cholangitis with Ankylosing Spondylitis. 原发性胆道胆管炎合并强直性脊柱炎。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-06-25 DOI: 10.4166/kjg.2022.048

Young Mi Hong, Ki Tae Yoon, Mong Cho

引用次数: 1

[Diagnosis and Treatment of Colonic Diverticular Disease]. 结肠憩室病的诊断与治疗

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-06-25 DOI: 10.4166/kjg.2022.072

You Sun Kim

{"title":"[Diagnosis and Treatment of Colonic Diverticular Disease].","authors":"You Sun Kim","doi":"10.4166/kjg.2022.072","DOIUrl":"https://doi.org/10.4166/kjg.2022.072","url":null,"abstract":"Colonic diverticulosis is one of the most common conditions of the digestive system and patients generally remain asymptomatic. However, about 20% of patients develop symptomatic diverticular disease such as acute diverticulitis or diverticular hemorrhage, and these have become a huge burden on healthcare systems worldwide. Recent understanding of the pathophysiology of diverticulosis and diverticular disease suggests the role of multiple factors including genetic and environment. Based on this understanding, a preventive strategy to reduce the risk factors of diverticulosis and diverticular disease is highly recommended. The diagnosis of the acute diverticulitis relies on imaging modalities such as an abdominal-pelvic CT scan together with symptoms and signs. Treatment of diverticular disease should be individualized and include modification of lifestyle, use of antibiotics, and surgery. Recent guidelines recommend pursuing less aggressive treatment for patients with acute diverticulitis. This review will provide an overview of both the existing and evolving understanding regarding colonic diverticulosis and diverticular disease and can help clinicians in the management of their patients with diverticular disease.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"79 6","pages":"233-243"},"PeriodicalIF":0.6,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40390251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Gastrointestinal Disease in the Population Aged 80 Years and above in Korea during Recent Decades: Multi-center Cross-sectional Study]. [近几十年来韩国80岁及以上人群胃肠道疾病的多中心横断面研究]。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-06-25 DOI: 10.4166/kjg.2022.032

Seo Kyung Woo, Shin Seung Kim, Woo Chul Chung, Joon Sung Kim, Byung-Wook Kim, Hyun Ho Choi, Sung Soo Kim

{"title":"[Gastrointestinal Disease in the Population Aged 80 Years and above in Korea during Recent Decades: Multi-center Cross-sectional Study].","authors":"Seo Kyung Woo, Shin Seung Kim, Woo Chul Chung, Joon Sung Kim, Byung-Wook Kim, Hyun Ho Choi, Sung Soo Kim","doi":"10.4166/kjg.2022.032","DOIUrl":"https://doi.org/10.4166/kjg.2022.032","url":null,"abstract":"Background/aims: Globally, the population aged 80 years or older is growing faster due to the rising life expectancy. Korea has already entered into an advanced aged society, and a post-aged society is expected in 2025. This study evaluated the patterns of gastrointestinal disease in the population aged 80 years or older during the recent decade in Korea.Method: This study retrospectively reviewed the medical records of patients admitted to the gastrointestinal department of Suwon St. Vincent's hospital, Incheon St. Mary's hospital, and Uijeongbu St. Mary's Hospital - general hospitals of Seoul-Gyeonggi province in Korea. It was a repeated cross-sectional study in 2009 and 2019.Results: The number of admitted patients aged 80 years or older increased from 549 (9.0%) in 2009 to 1,073 (14.4%) in 2019 (p<0.01). As for the in-hospital mortality, there was no significant difference (p=0.25). On the other hand, the combined morbidities increased, and the duration of admission also increased (7.2±7.8 days vs. 8.1±8.2 days, p=0.03). The number of upper gastrointestinal hemorrhage and patients who are bleeding associated with drugs users increased (p<0.01). The proportion of lower gastrointestinal disease decreased (p<0.01) because of the decrease in procedure-related admissions (p<0.01). The number of those with pancreaticobiliary tract disease increased markedly (p<0.01), and the rate of cases that could not perform the procedure decreased (p=0.04).Conclusion: The patterns of gastrointestinal disease in the population aged 80 years or older have changed in the recent decade in Korea. Hence, more preparation for this medical environment is needed.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"79 6","pages":"244-251"},"PeriodicalIF":0.6,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40390252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic Ultrasonography-guided Gastrojejunostomy for Patients with Gastric Outlet Obstruction and Pyloric Metal Stent Dysfunction. 超声内镜引导下胃空肠造口术治疗胃出口梗阻及幽门金属支架功能障碍。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-06-25 DOI: 10.4166/kjg.2022.045

Byung Sun Kim, Sung Yeol Yang, Won Dong Lee, Jae Sun Song, Min A Yang, Gum Mo Jung, Jin Woong Cho, Ji Woong Kim

引用次数: 0

Gastric Malignant Peripheral Nerve Sheath Tumor in Type 1 Neurofibromatosis. 1型神经纤维瘤病伴胃周围神经鞘恶性肿瘤。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-06-25 DOI: 10.4166/kjg.2022.022

Hyun Seung Hwang, Yun Jin Jeong, Kyung Han Nam, Sung Jin Oh, Yong Eun Park

{"title":"Gastric Malignant Peripheral Nerve Sheath Tumor in Type 1 Neurofibromatosis.","authors":"Hyun Seung Hwang, Yun Jin Jeong, Kyung Han Nam, Sung Jin Oh, Yong Eun Park","doi":"10.4166/kjg.2022.022","DOIUrl":"https://doi.org/10.4166/kjg.2022.022","url":null,"abstract":"Gastric malignant peripheral nerve sheath tumors (MPNSTs) are extremely rare spindle cell sarcomas that arise within the peripheral nerves of the gastrointestinal tract. MPNST can present as a mass that may or may not be accompanied by obstruction or bleeding. Type 1 neurofibromatosis (NF) is an autosomal dominant genetic disorder with an incidence of 1 in 2,500-3,000. Plexiform neurofibromas in Type 1 NF can undergo a malignant transformation to MPNSTs. Approximately half of the incidence of MPNST is associated with the NF-1 gene. MPNST behaves aggressively, and radical excisional surgery is important for treatment. Recurrence and metastasis are significant, even after a radical excision. Despite multidisciplinary treatment, the five-year survival rate is only 30-50%. This paper reports the case of a 47-year-old man with Type 1 NF who presented with hemorrhage of a gastric subepithelial lesion. He underwent surgery under the suspicion of a gastrointestinal stromal tumor, but it was diagnosed as MPNST after confirming the histopathological appearance and immunohistochemical profiles. In addition, the large mass invaded the spleen and diaphragm. Radical surgery was performed, and additional chemotherapy was administered. This paper reports the experience of a patient with NF 1 with advanced MPNST discovered due to a subepithelial lesion.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"79 6","pages":"265-269"},"PeriodicalIF":0.6,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40391235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

[Factors Associated with the Clinical Outcomes of Iatrogenic Colonic Perforation]. [与医源性结肠穿孔临床结果相关的因素]。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-05-25 DOI: 10.4166/kjg.2022.024

H. Lee, H. Lee, D. Cheung, J. Kim, Soo-Heon Park

{"title":"[Factors Associated with the Clinical Outcomes of Iatrogenic Colonic Perforation].","authors":"H. Lee, H. Lee, D. Cheung, J. Kim, Soo-Heon Park","doi":"10.4166/kjg.2022.024","DOIUrl":"https://doi.org/10.4166/kjg.2022.024","url":null,"abstract":"Background/Aims\u0000This study evaluated the incidence of iatrogenic colonic perforation (ICP) in a high-volume center and analyzed the clinical outcomes and associated factors.\u0000\u0000\u0000Methods\u0000As a retrospective study of the electronic medical records, the whole data of patients who underwent colonoscopy from June 2004 to May 2020 were reviewed.\u0000\u0000\u0000Results\u0000During 16 years, 69,458 procedures were performed, of which 60,288 were diagnostic and 9,170 were therapeutic. ICP occurred in 0.027% (16/60,288) for diagnostic colonoscopies and in 0.076% (7/9,170) for therapeutic purposes (p=0.015; hazard ratio 2.878; 95% CI, 1.184-6.997). Fifty-two percent (12 cases) were managed with endoscopic clip closure, and 43.5% (10 cases) required surgery. The reasons for the procedure and the procedure timing appeared to affect the treatment decision. Perforations during therapeutic colonoscopy were treated with surgery more often than those for diagnostic purposes (66.7% [4/6] vs. 37.5% [6/16], p=0.221). Regarding the timing of the procedure, ICP that occurred in the afternoon session was more likely treated surgically (56.3% [9/16] vs. 0/5, p=0.027). Mortality occurred in two patients (2/23, 8.7%). Both were aged (mean age 84.0±1.4 vs. 65.7±10.5, p<0.001) and lately recognized (mean elapsed time [hours], 43.8±52.5 vs. 1.5±3.0, p<0.001) than the surviving patients.\u0000\u0000\u0000Conclusions\u0000ICP occurs in less than 0.1% of cases. The events that occurred during the morning session were more likely managed endoscopically. Age over 80 years and a longer time before perforation recognition were associated with mortality.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"9 1","pages":"210-216"},"PeriodicalIF":0.6,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76858518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Endoscopic Ultrasound-guided Drainage in Pancreatobiliary Diseases]. 超声内镜引导下胰胆道疾病引流术

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-05-25 DOI: 10.4166/kjg.2022.064

Tae Hyeon Kim, H. Chon

引用次数: 2

Primary Esophageal Malignant Melanoma in Korea: Clinical features, Management and Prognosis. 韩国原发性食管恶性黑色素瘤:临床特征、管理和预后。

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The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2022-05-25 DOI: 10.4166/kjg.2022.031

Hyung-Hoon Oh, Y. Jung, B. Han, Chan-Muk Im, Hyung-Joo Yu, Y. Joo

{"title":"Primary Esophageal Malignant Melanoma in Korea: Clinical features, Management and Prognosis.","authors":"Hyung-Hoon Oh, Y. Jung, B. Han, Chan-Muk Im, Hyung-Joo Yu, Y. Joo","doi":"10.4166/kjg.2022.031","DOIUrl":"https://doi.org/10.4166/kjg.2022.031","url":null,"abstract":"Primary esophageal melanoma is a rare disease with a poor prognosis. To date, 18 cases have been reported in Korea. Four patients visited the Chonnam National University Hwasun Hospital with dysphagia, followed by epigastric pain and discomfort, odynophagia, and weight loss. Esophagogastroduodenoscopy revealed a black pigmented polypoid mass, protruding mass, or black-pigmented flat lesions. Two patients had distant metastases and lymphadenopathies in imaging studies. Two patients underwent esophagectomy and intrathoracic esophagogastrostomy. One patient was treated with chemotherapy and interferon-alpha. The other patient declined further treatment. The routine histology using H&E revealed brown-colored atypical melanocytes. Immunohistochemical staining exhibited strong reactivity for Melan-A, S-100, and HMB-45 proteins. The biopsy specimens were interpreted to be malignant melanoma. One patient had multiple distant metastases 13 months after surgery. The other patient had no recurrence for 33 months after surgery. The patient treated with chemotherapy and interferon-alpha showed disease progression in the follow-up examination. Primary esophageal melanoma in Korea is a rare disease characterized by aggressive behavior, early metastasis, and poor prognosis.","PeriodicalId":22736,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"38 1","pages":"222-227"},"PeriodicalIF":0.6,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84593698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0