The Journal of Pure and Applied Chemistry Research最新文献_第3页

Anion Effect and Ligand Preference in the Precipitation of Ni(II) Complex from Methanolic Solution: Case of Tartrate vs Pyrazine 从甲醇溶液中沉淀Ni(II)配合物的阴离子效应和配体偏好:酒石酸盐和吡嗪的例子

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-08-31 DOI: 10.21776/ub.jpacr.2022.011.02.670

Yenni Finisia, Siti Mutrofin, Yuniar Ponco Prananto

{"title":"Anion Effect and Ligand Preference in the Precipitation of Ni(II) Complex from Methanolic Solution: Case of Tartrate vs Pyrazine","authors":"Yenni Finisia, Siti Mutrofin, Yuniar Ponco Prananto","doi":"10.21776/ub.jpacr.2022.011.02.670","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.02.670","url":null,"abstract":"This research aims to incorporate pyrazine in the synthesis of Ni(II)-tartrate-pyrazine metal organic frameworks or Ni(II)-T-P MOF as candidate of porous material. Synthesis of the targeted MOF was conducted at room temperature in a methanolic solution by mixing Ni(II) solution, L-tartaric acid (T), and pyrazine (P) solutions sequentially in various molar ratios (Ni(II):T:P = 1:1:0; 1:0:2; 1:2:2; and 1:2:4) using two different Ni(II) salts (chloride and nitrate). Solid products were characterized by infrared spectroscopy, qualitative anion identification test, melting point test, and scanning electron microscopy. The result shows that type of nickel salt affects the precipitation of Ni(II) complex, in which pale blue solids were precipitated out only from the chloride reactions (1:0:2, 1:2:2, and 1:2:4). IR and SEM analyses from the 1:2:2 and 1:2:4 reactions show identical result as also shown by the 1:0:2 reaction, whereas qualitative anion identification test result suggests that the chloride is uncoordinated to the Ni(II). The targeted Ni(II)-T-P is unsuccessfully obtained, instead the product is proposed to be [Ni(pyrazine)x(H2O)(6-x)]Cl2. although the tartaric acid was doubled and firstly reacted with the Ni(II), the pyrazine still has higher preference to coordinate to the Ni(II) center than the tartrate ligand.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"174 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78113305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Novel Antimalarial Drug Screening Based on Methyl Eugenol, Cinnamaldehyde, and Thiosemicarbazone with Cysteine Protease Inhibition: In Silico Molecular Docking, Molecular Dynamics, and ADMET Studies 基于半胱氨酸蛋白酶抑制的甲基丁香酚、肉桂醛和硫代氨基脲的新型抗疟药物筛选:硅分子对接、分子动力学和ADMET研究

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-08-31 DOI: 10.21776/ub.jpacr.2022.011.02.652

L. Arianie, Feri Eko Hermanto, Elvina Dhiaul Iftitah, W. Warsito, N. Widodo

{"title":"Novel Antimalarial Drug Screening Based on Methyl Eugenol, Cinnamaldehyde, and Thiosemicarbazone with Cysteine Protease Inhibition: In Silico Molecular Docking, Molecular Dynamics, and ADMET Studies","authors":"L. Arianie, Feri Eko Hermanto, Elvina Dhiaul Iftitah, W. Warsito, N. Widodo","doi":"10.21776/ub.jpacr.2022.011.02.652","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.02.652","url":null,"abstract":"Plasmodium falciparum malaria contributes to significant global diseases. Computer-aided drug design, screening, and discovery were used to analyze a novel series of Methyl Eugenol Benzaldehyde Thiosemicarbazone (MEBThi) and Methyl Eugenol Cinnamaldehyde Thiosemicarbazone (MECThi) derivatives for malaria falciparum inhibition. This present study showed that 16 molecules from 28 of MEBThi and MECThi have affinities and interaction with active-site residues of cysteine protease, a key player in erythrocyte proliferation of P. falciparum. 13-MECThi demonstrates the best binding affinity at ˗8.0 kcal/mol while co-drug ˗5.6 kcal/mol. Physicochemical and pharmacokinetic assays of 13- MECThi have also revealed this potent compound. Toxicity analysis shows that 13-MECThi does not have mutagenicity and carcinogenicity characters, whereas co-drug has mutagenicity probability. The molecular dynamic evaluation illustrated that the 13-MECThi complex has higher Root Mean Square Deviation (RMSD) values, indicating its structure was more flexible than the chloroquine complex. Root Mean Square Fluctuation (RMSF) complex of receptor and 13-MECThi has no fundamental differences with chloroquine complex. This designed compound should be considered a falciparum antimalarial drug.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75891144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Synthesis of Chitosan Magnetic Nanoparticles using Glutaraldehyde and Tripolyphosphate as Crosslinker 以戊二醛和三聚磷酸为交联剂合成壳聚糖磁性纳米颗粒

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-08-31 DOI: 10.21776/ub.jpacr.2022.011.02.683

Indri Alidha Rahmani, Ani Mulyasuryani, U. Andayani

{"title":"Synthesis of Chitosan Magnetic Nanoparticles using Glutaraldehyde and Tripolyphosphate as Crosslinker","authors":"Indri Alidha Rahmani, Ani Mulyasuryani, U. Andayani","doi":"10.21776/ub.jpacr.2022.011.02.683","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.02.683","url":null,"abstract":"Chitosan is an abundant natural polymer, which able to adsorb Pb2+. However, chitosan has the drawback of being unstable in acid and alkaline conditions, so it needs cross-linking. In this article, we will compare the usage of two crosslinkers, glutaraldehyde (GD) and tripolyphosphate (TPP), to solve these issues. The synthesis of chitosan magnetic nanoparticles was carried out by co-precipitation with the addition of glutaraldehyde under acidic conditions and the addition of TPP under alkaline conditions. The results showed that the FTIR spectrum gave characteristic bands at 3131.96 cm-1 (OH and NH), 1635.86 cm-1 (C=O), 1401.97 cm-1 (CN), ~1110 cm-1 (COC), and ~617 cm-1 (Fe-O). SEM analysis showed that the surface morphology of CMNP-GA particle aggregation was clear more than that of CMNP-TPP. The size of the synthesized nanoparticles was determined by PSA analysis, which was 131.95 µm and 137.10 µm, respectively. The results of the XRD analysis showed that, in addition to the Fe3O4 and chitosan phases, the produced CMNP also contained γFe2O3 phase, which was considered to be caused by Fe3O4 oxidation","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87445283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Xylose as Product Inhibitor in Xylanase from Aspergillus niger, Basillus subtilis, and Tricodherma reesei: Insilico and Experimental Review Approach 木糖作为黑曲霉、枯草Basillus和里氏木霉木聚糖酶产物抑制剂的初步研究与实验综述

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-08-31 DOI: 10.21776/ub.jpacr.2022.011.02.639

S. Hadiantoro, Dyah Ratna Wulan, Y. Maryanty

{"title":"Study of Xylose as Product Inhibitor in Xylanase from Aspergillus niger, Basillus subtilis, and Tricodherma reesei: Insilico and Experimental Review Approach","authors":"S. Hadiantoro, Dyah Ratna Wulan, Y. Maryanty","doi":"10.21776/ub.jpacr.2022.011.02.639","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.02.639","url":null,"abstract":"Bioinformatics is helpful for solving molecular biology problems computationally with the advantage of being safe, free from chemical waste, secure, cost-effective, and can shorten research time. The issues that arise can be in the form of degradation of the xylanase enzyme using some microorganisms like Aspergillus niger, Bacillus subtilis, and Trichoderma reesei on lignocellulose bonds. To predict the optimum conditions for this enzymatic reaction has used bioinformatics applications through substrate enzymes obtained from protein data banks. The purpose of this study was to determine the optimum conditions for obtaining xylanase enzymes from the microorganisms Aspergillus niger, Bacillus subtilis, and Trichoderma reesei by bioinformatics (in silico). This research was conducted in bioinformatics using a RCSB Protein Data Bank database and PubChem. The programs used to see the interaction between substrate enzymes are PyMol, PyRx, and LigPlot. The best conditions based on the results of bioinformatics simulations will form the basis for producing xylanases on a laboratory scale. In this study, the results of interaction data between Bacillus subtilis and D-xylose, Aspergillus niger with D-xylose, and Trichoderma reesei with D-xylose have a binding affinity value of -5.2 kcal/mol; -5.1 kcal/mol; and -4.3 kcal/mol respectively.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"66 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72630007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary Metabolites of Nicotiana tabacum and Their Biological Activities: A Review 烟草次生代谢产物及其生物活性研究进展

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-08-31 DOI: 10.21776/ub.jpacr.2022.11.02.646

Devi Anggraini Putri, Riyadatus Solihah, Rianur Oktavia, S. Fatmawati

引用次数: 0

Acid Isolation Techniques for Silica isolation from Rice Husk and Determination of Its Physicochemical Properties 稻壳中二氧化硅的酸分离技术及其理化性质的测定

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-04-30 DOI: 10.21776/ub.jpacr.2022.011.01.641

Siti Mutrofin, Diah Mardiana, Rachmat Triandi Tjahjanto

{"title":"Acid Isolation Techniques for Silica isolation from Rice Husk and Determination of Its Physicochemical Properties","authors":"Siti Mutrofin, Diah Mardiana, Rachmat Triandi Tjahjanto","doi":"10.21776/ub.jpacr.2022.011.01.641","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.01.641","url":null,"abstract":"Previous research showed that rice husk has a high silica content so it becomes an alternative for processing rice waste. The acid leaching method is a technique to isolate silica by adding an acid solution. The research aim is to obtain the optimum silica yield and determine the chemical ash content of rice husks (rice IR-64,). Rice husks were first calcined at two various temperatures and times. The average yields obtained were 19.54% (500oC / 1 hr), 18.42% (500oC / 2 hrs), 25.03% (700oC /1 hr), and 22.4% (700oC/2 hrs). The physical appearance of ash was grains and white (700 oC/1hr), that were rinsed with 1 M HCl solution to remove impurities. Added 1 M NaOH was to form sodium silicate. The last step was to isolate silica using different concentrations of HCl and HNO3 (3 M, 2 M, and 1 M). The highest result was 99.87% of silica under HNO3 1 M solution. An infrared study supports that the isolated product was silica, with the presence of prominent peaks at 1102 cm-1 (stretching Si-O) and 471 cm-1 (bending Si-O). A unique peak at 958 cm-1 for Si-O-Ca present at the isolated silica using HCl 3 M, gives information on inosilicate type structure. X-ray diffraction analysis with QualX application showed that silica had cristobalite and wollastonite peaks, and the value of crystallinity index was about 63.91%.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90175162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silver Nanoparticles Biosynthesis Using Mangosteen (Garcinia Mangostana L.) Rind Extract For Environmentally Friendly Liquid Disinfectant Active Ingredients 山竹果生物合成纳米银果皮提取物为环保型液体消毒剂活性成分

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-04-30 DOI: 10.21776/ub.jpacr.2022.011.01.654

Abdul Haris Watoni, La Ode Ahmad Nur Ramadhan, Muhammad Daffa Rahmatullah, Angelina Ike Dwiyanti Kalpen Bunga, S. Supardi

{"title":"Silver Nanoparticles Biosynthesis Using Mangosteen (Garcinia Mangostana L.) Rind Extract For Environmentally Friendly Liquid Disinfectant Active Ingredients","authors":"Abdul Haris Watoni, La Ode Ahmad Nur Ramadhan, Muhammad Daffa Rahmatullah, Angelina Ike Dwiyanti Kalpen Bunga, S. Supardi","doi":"10.21776/ub.jpacr.2022.011.01.654","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.01.654","url":null,"abstract":"Disinfectant is one of the materials that can be used to inactivate pathogenic microorganisms, but most of the disinfectants used in the community are disinfectants made from synthetic chemicals that are harmful to the environment. The purpose of this study was to synthesize and evaluate the antimicrobial activity of silver (Ag) nanoparticles-mangosteen rind extract as an active ingredient in an environmentally friendly disinfectant formula. The synthesis process of silver nanoparticles was carried out by adding a bioreductant of mangosteen rind extract into a 0.01 M AgNO3 solution precursor with a variation of the precursor : bioreductor volume ratio of 1:1, 1:2, 1:3, 1:4, 1:5, and 1:6, respectively. The results of the analysis with UV-Vis spectroscopy showed that the silver nanoparticles of mangosteen rind extract had good stability. The decrease in the absorption peak in the FTIR spectrum at a wave number of 3390.86 cm-1 indicates the contribution of the –OH group in the bioreductant compound in the reduction process of silver nanoparticles. PSA analysis and digital microscopy showed that the diameter of the synthesized silver nanoparticles with a volume ratio of bioreductor : precursor 1:1 was 82.33 nm. The antimicrobial activity test showed that the active ingredient mixture of silver-mangosteen rind extract with a composition of 1:1 had the best activity in deactivating of gram-positive Staphylococcus aureus and gram-negative Escherichia coli bacteria. The results of this study indicate that the mixture also can be used as active ingredients for environmentally friendly liquid disinfectants.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79606926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Determination of the radical-scavenging activities and identification of anthocyanins from Hexalobus monopetalus ripe fruits 六瓣草成熟果实清除自由基活性的测定及花色苷的鉴定

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-04-30 DOI: 10.21776/ub.jpacr.2022.011.01.608

A. Noba, A. Hema, E. Kabré, Bazoin Sylvain Raoul Bazié, P. Ouôba, Constantin M. Dabiré, Remy K. Bationo, Moumouni Koala, E. Palé, M. Nacro

{"title":"Determination of the radical-scavenging activities and identification of anthocyanins from Hexalobus monopetalus ripe fruits","authors":"A. Noba, A. Hema, E. Kabré, Bazoin Sylvain Raoul Bazié, P. Ouôba, Constantin M. Dabiré, Remy K. Bationo, Moumouni Koala, E. Palé, M. Nacro","doi":"10.21776/ub.jpacr.2022.011.01.608","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.01.608","url":null,"abstract":"A wild fruit from classified forest of Dindéresso was analyzed for total phenolics, flavonoids, anthocyanins compounds using the Folin-Ciocalteu reagent, spectrophotometric method of Zhishen and colleagues and by the differential pH method respectively. Free radical-scavenging activities of studied fruits extracts were estimated using diammonium 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) salt method. Three major anthocyanins were identified using high performance liquid chromatography coupled with spray ionization interface mass spectrometry. Three identified anthocyanins in fruit were reported to be cyanidin 3-O-(p-coumaroyl) glucoside, pelargonidin 3-O-glucoside and pelargonidin 3-O-rutinoside. In addition, H. monopetalus fruit contained of about 1165±3.1 mg of GAE per 100 g of fresh fruit, 4490±20.2 mg of QE per 100 g of fresh fruit, and 36±0.17 mg of cyanidin 3-O-glucoside equivalents per 100 g of fresh fruit. Total anthocyanin extract had an EC50 = 4.24 mg per mL and a TEC50 time of 21 minutes (intermediate reaction). This free radical-scavenging activity was very low compared to those of the references used (0.024 and 0.034 mg/mL respectively for ascorbic acid and Trolox). The low antiradical activity and reactivity of the H. mucronata extract could be explained by several factors. In any case, fruits of this species were potential sources of natural bioactive substances having beneficial effects on the health of consumers.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"312 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76520853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Effect of Klika Ongkea Extract (Mezzetia parviflora Becc.) on Pancreatic β-Cells Regeneration by Streptozotocin-Induced in Wistar Rats 苦参提取物对链脲霉素诱导Wistar大鼠胰腺β-细胞再生的影响

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-04-30 DOI: 10.21776/ub.jpacr.2022.011.01.618

Jangga Jangga, M. Mansur, S. Latu

{"title":"The Effect of Klika Ongkea Extract (Mezzetia parviflora Becc.) on Pancreatic β-Cells Regeneration by Streptozotocin-Induced in Wistar Rats","authors":"Jangga Jangga, M. Mansur, S. Latu","doi":"10.21776/ub.jpacr.2022.011.01.618","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.01.618","url":null,"abstract":"This study aimed to determine the effect of Klika ongkea (Mezzetia parviflora Becc.) extract on the regeneration of pancreatic β-cells on Wistar rats that were induced using streptozotocin. Streptozotocin (STZ) with a 40 mg/kg BW dose was used in this study. Eighty adult male Wistar rats were used for this study. The animals were divided into four groups, Group I, as a healthy controls; Group II as an STZ-induced, Group III, STZ-induced and treated with galvus (Vildagliptin) 0.9 mg/200 g BW; Group IV, STZ-induced and treated with Klika ongkea 100 mg/kg BW. This study was conducted for 28 days. Four animals each group on the 1st, 7th, 14th, 21st and 28th days were observed to analyze the number of pancreatic β-cells. On the last day, pancreases were isolated and stained with hematoxylin & eosin (H&E) to analyze the regeneration of pancreatic β-cells. The data analysis was performed using an Independent-Sample T-Test to compare the number of pancreatic β-cells. The results showed that the administration of Klika ongkea extracts affected the pancreatic β-cells regeneration. These findings suggest that Klika ongkea has an effect on the regeneration of pancreatic β-cells in streptozotocin-induced rats.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87838421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Characterization of Complex Compounds from Cadmium(II) Chloride and Cobalt(II) Chloride with N,N'-Diethylthiourea 氯化镉(II)和氯化钴(II)与N,N'-二乙基硫脲配合物的合成与表征

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-04-30 DOI: 10.21776/ub.jpacr.2022.011.01.640

Reza Mega Wahyuni, Husni Wahyu Wijaya, Meyga Evi Ferama Sari, I. Wayan Dasna, Nani Farida

{"title":"Synthesis and Characterization of Complex Compounds from Cadmium(II) Chloride and Cobalt(II) Chloride with N,N'-Diethylthiourea","authors":"Reza Mega Wahyuni, Husni Wahyu Wijaya, Meyga Evi Ferama Sari, I. Wayan Dasna, Nani Farida","doi":"10.21776/ub.jpacr.2022.011.01.640","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.01.640","url":null,"abstract":"The synthesis of ionic complexes of cadmium(II) chloride and cobalt(II) chloride with N,N'-diethylthiourea (detu) ligands has not been previously reported. Therefore, in this research, the synthesis was carried out to study the structure and characterization of the two ionic complex compounds. The cadmium(II)-detu ionic complex was synthesized using the direct reaction method with a ratio between Cd(II) salt and detu ligand of 1:2. Meanwhile, the cobalt(II)-detu ionic complex was synthesized with a ratio between Co(II) salt and detu ligand of 2:4. The cadmium(II)-detu and cobalt(II)-detu ionic complexes have melting points of 105-108 ˚C and 122-125 ˚C, respectively. The electrical conductivity of the cadmium(II)-detu and cobalt(II)-detu complexes showed that the complexes were ionic. The FTIR analysis showed the shifting of the C=S functional group’s band to the smaller wavenumber, which indicates the coordinating detu ligand to the cadmium(II) and cobalt(II) through the S atom. The indirect evidence from 1H-NMR showed that CH3 and CH2 only slightly shifted between the free detu ligand and the Cd-detu and Co-detu complexes.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85182391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1