The Journal of Pure and Applied Chemistry Research最新文献_第2页

Comparison of Fabrication Technique and Carrier Oil to Curcumin Nanoemulsion Properties 制备工艺及载体油对姜黄素纳米乳性能的影响

The Journal of Pure and Applied Chemistry Research Pub Date : 2023-04-26 DOI: 10.21776/ub.jpacr.2023.012.01.701

Z. Ningsih, Sepriana Puspita Dewi Syaiful, Maria Lucia A.D. Lestari, Diah Mardiana, B. Kamulyan

{"title":"Comparison of Fabrication Technique and Carrier Oil to Curcumin Nanoemulsion Properties","authors":"Z. Ningsih, Sepriana Puspita Dewi Syaiful, Maria Lucia A.D. Lestari, Diah Mardiana, B. Kamulyan","doi":"10.21776/ub.jpacr.2023.012.01.701","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2023.012.01.701","url":null,"abstract":"Turmeric (Curcuma longa L.) is included in the rhizome plant containing curcumin which has various therapeutic properties. However, curcumin has poor bioavailability. The manufacture of nanoemulsion is expected to increase curcumin bioavailability. This study aims to compare 3 methods (wet-ball milling, ultrasonication and microfluidic) and 3 carrier oils (soybean, virgin coconut, and olive oil) in the production of curcumin nanoemulsion. Wet-ball milling reduces particle size through grinding process using milling beads in liquid medium. Microfluidic decreases the particle size via collision of emulsion components in microchannel while ultrasound utilizes sound-wave energy to break down the particle size. Parameters compared were particle size, polydispersity index and entrapment efficiency. Particle size and polydispersity index were observed using Particle Size Analyzer with Dynamic Light Scattering technique while entrapment efficiency was measured based on the curcumin absorbance in UV-Visible spectrophotometer at 420 nm. Our study concludes that microfluidic is the most effective and efficient fabrication method which produces the smallest particle size and polydispersity index compared to ultrasonication and microfluidic. The resulting particle sizes using microfluidic are 154, 140 and 132 nm with polydispersity index of 0.224; 0.200 and 0.208 in soybean, virgin coconut, and olive oil respectively. However, entrapment efficiency is best achieved using wet-ball milling method with the average value of 49±10%. Soybean oil appears to be the most curcumin solubilizing oil compared to olive and virgin coconut oil. Thus, it can be concluded that fabrication methods and carrier oils determine curcumin nanoemulsion properties.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"386 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74044781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial Activity of Legundi Leaf (Vitex trifolia) Essential Oil Using In-Vitro and In-Silico Methods 豆科植物叶精油体外和体外抑菌活性研究

The Journal of Pure and Applied Chemistry Research Pub Date : 2023-04-26 DOI: 10.21776/ub.jpacr.2023.012.001.738

Retno Indriatie, W. Warsito, M. Masruri

{"title":"Antibacterial Activity of Legundi Leaf (Vitex trifolia) Essential Oil Using In-Vitro and In-Silico Methods","authors":"Retno Indriatie, W. Warsito, M. Masruri","doi":"10.21776/ub.jpacr.2023.012.001.738","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2023.012.001.738","url":null,"abstract":"Staphylococcus aureus causes many severe diseases, such as meningitis, lung infection, and hematogenous osteomyelitis. The prolonged use of antibiotic drugs leads to antimicrobial resistance (AMR), decreasing their effectiveness against S. aureus. Therefore, novel drugs isolated from natural products have been the focus of many researchers to solve that problem. The essential oils isolated from Vitex trifolia leaf have many pharmacological activities, including antibacterial and antifungal activities. In this research, essential oil was isolated by distillation, followed by GC-MS analysis. The antibacterial activity of the essential oil was conducted using a disc diffusion test (KirbyBauer) and by molecular docking study. The essential oil yield from distillation was 0.13%, containing major compounds such as sabinene, eucalyptol, terpinen-4-ol, αterpineol, limonene, and caryophyllene. The essential oil gave intermediate inhibition against S. aureus with a 6.91 ± 0.03 mm inhibition zone in 20 mg/mL of the sample. Using molecular docking study, caryophyllene and α-terpineol were the key compounds for inhibiting the active site of tyrosyl-tRNA synthetase, sortase A, and dihydrofolate reductase that are responsible for the S. aureus growth and development","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85174926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis of Struvite Crystal (MgNH4PO4.6H2O) from Laundry Waste to Consider its Potential as a Plant Fertilizer: Stirring and Processing Temperature Effect 从洗衣废物中合成鸟粪石晶体(MgNH4PO4.6H2O)及其作为植物肥料的潜力:搅拌和加工温度效应

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.697

Dyah Suci Perwitasari, Nur Aini Fauziyah, Pardi Sampe Tola

{"title":"Synthesis of Struvite Crystal (MgNH4PO4.6H2O) from Laundry Waste to Consider its Potential as a Plant Fertilizer: Stirring and Processing Temperature Effect","authors":"Dyah Suci Perwitasari, Nur Aini Fauziyah, Pardi Sampe Tola","doi":"10.21776/ub.jpacr.2022.011.03.697","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.03.697","url":null,"abstract":"This paper aimed to process phosphate from laundry waste to be struvite crystal by precipitation and crystallization methods. In general, phosphates are difficult to remove by conventional treatment technologies. Therefore, precipitation and crystallization methods can be an alternative choice for phosphate recovery. Precipitation and crystallization methods by adding KOH can serve to remove dissolved phosphate content in wastewater, as well as convert it into a solid form that can be reused as industrial raw materials. The research variables used were stirring temperature (25, 30, and 35 C) and stirring speed (100, 125, 150, and 200 rpm). By using X-ray Fluorescence (XRF) and Scanning Electron Microscope (SEM-EDX), the analysis showed that the highest percentage of phosphate removal was at a stirring speed of 100 rpm at 30°C, which was 47.5%. X-ray Diffraction (XRD) was also carried out on several samples and it was confirmed that the dominant crystal phase formed was a struvite (MgNH4PO4.6H2O) for all samples, and secondary phase magnesium phosphate hydrate (Mg3(PO4)2.8H2O was found in a stirring speed of 100 rpm at 30°C. The morphology of the struvite crystals formed resembles irregular flakes by using SEM.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74322891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mini Electrode Based on Chitosan-Activated Carbon Membrane for Detection of Paracetamol in Herbal Medicine 壳聚糖-活性炭膜微型电极检测中草药中扑热息痛

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.677

Ani Mulyasuryani, Rachmat Triandi, Zainul Abidin

引用次数: 0

Synthesis and Characterization of Molecularly Imprinted Polymers (MIPs) Using Humic Acid 腐植酸分子印迹聚合物(MIPs)的合成与表征

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.656

T. Putri, M. Ali Zulfikar, D. Wahyuningrum, Iwan Syahjoko Saputra

引用次数: 0

Synthesis and Characterization of Cellulose Acetate and Nanocellulose Acetate from Sengon Agroindustrial Waste (Paraserianthes falcataria) 从森贡农工废渣中合成醋酸纤维素和纳米醋酸纤维素的研究

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.644

Nur Ikhtiarini, M. Masruri, Siti Mariyah Ulfa, W. Widodo

引用次数: 1

Study of Cu Recovery Comparison of Fresh, Stockpiled, and Mixed Ores Processing in Batu Hijau Mine – Sumbawa Island, Indonesia 印尼松巴哇岛Batu Hijau矿鲜、堆、混矿石铜回收比较研究

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.691

S. Hadi, Agung D. Syakti, Didik S. Agustawijaya, Wahyu D. Silviani, Karel Pramono, R. Anungstri, J. Waworuntu

{"title":"Study of Cu Recovery Comparison of Fresh, Stockpiled, and Mixed Ores Processing in Batu Hijau Mine – Sumbawa Island, Indonesia","authors":"S. Hadi, Agung D. Syakti, Didik S. Agustawijaya, Wahyu D. Silviani, Karel Pramono, R. Anungstri, J. Waworuntu","doi":"10.21776/ub.jpacr.2022.011.03.691","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.03.691","url":null,"abstract":"Batu Hijau mine is one of the mining areas in Indonesia that have been operated for 20 years. The main concentrate product in Batu Hijau contains the primary minerals copper (Cu) and gold (Au). However, the mine is not only processing the fresh mined ore but also store the low-grade ore in the stockpile. Therefore, this study compares the Cu recovery in different ore stockpile processing on and changes in the concentration of dissolved Cu in the tailings that potentially contaminated the environment. Chemical analysis of solid and dissolved Cu uses standard methods by strictly carrying out quality assurance and quality control (QA/QC) procedures to ensure the resulting data has high validity. The results showed that there is a slight increase in Cu’s solubility in liquid fraction of tailings and the recovery decrease when ores were processed from stockpiles. However, the recovery reduction is anticipated by flotation with controlled potential sulphidisation (CPS) using sodium hydrosulphide (NaHS). Besides, the CPS also ensure that only small amount of dissolved Cu that dumped in the tailings. Hence, the dissolved Cu concentration can be monitories to reduce the possible impact on the environment.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"136 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88948209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Microsheets Bi4Ti3O12 and Bi4Ti2.95V0.05O12 via Molten NaCl-KCl Salt Method 熔融NaCl-KCl盐法制备Bi4Ti3O12和Bi4Ti2.95V0.05O12微片

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.703

A. Prasetyo, Andy Nur Muhammad Guntur, Suci Noerfaiqotul Himmah, N. Aini, Usman Ali Rouf, A. Aziz

引用次数: 0

Iron Metal Ion Adsorption Capacity on Palm Oil Mill Effluent (POME) Using Montmorillonite Adsorbent 蒙脱土吸附剂对棕榈油厂废液(POME)中铁金属离子的吸附性能

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-12-31 DOI: 10.21776/ub.jpacr.2022.011.03.657

Maria Dayanti Mellanie, Tisna Harmawan, P. Wahyuningsih

{"title":"Iron Metal Ion Adsorption Capacity on Palm Oil Mill Effluent (POME) Using Montmorillonite Adsorbent","authors":"Maria Dayanti Mellanie, Tisna Harmawan, P. Wahyuningsih","doi":"10.21776/ub.jpacr.2022.011.03.657","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.03.657","url":null,"abstract":"Palm oil mill effluent (POME) is the most produced waste among other types of waste, which is around 60% in every 100% processing of fresh fruit bunches containing heavy metals, namely ferrous metal (Fe). Montmorillonite (MMT) is one of the best adsorbents used to reduce the concentration of Fe in POME. In addition, this mineral (MMT) also has a high cation fertilization capacity so that the space between layers of MMT is able to accommodate large amounts of cations and make MMT a unique material. In this review, the assurance of the mass variety of the MMT as adsorbent and the variety of the contact time on the adsorption capacity of Fe metal in POME was resolved utilizing a Atomic Absorption Spectrophotometer (AAS) and surface morphology analysis of MMT before and after adsorption using Scanning Electron Microscope (SEM). Based on the results of AAS analysis, the greater the mass of the adsorbent, the higher the amount of Fe adsorbed from the POME. Moreover, the longer the contact time between MMT and Fe, the higher the amount of Fe in the palm oil mill effluent adsorbed on the adsorbent surface. The best adsorption conditions occurred at an adsorbent mass of 8.5 g MMT in 50 mL adsorbate and a contact time of 5 hours with an adsorption capacity of 0.0383 mg/g. The results of the SEM showed the presence of empty spaces in the MMT before adsorption, in which after adsorption white granules occupies the empty spaces evenly on the surface of the MMT. The granules indicate the presence of Fe metals in the POME samples which are adsorbed on the MMT surface.","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73936721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Solvent Type and Germination Time on The Level of Free Amino Acid and Peptides of Germinated Pigeon Pea (Cajanus cajan (L.) Millsp) Extract 溶剂类型和萌发时间对萌发鸽豆游离氨基酸和多肽水平的影响Millsp)提取

The Journal of Pure and Applied Chemistry Research Pub Date : 2022-08-31 DOI: 10.21776/ub.jpacr.2022.011.02.672

K. Ratnayani, Ni Wayan Wisaniyasa, Ni Putu Wiwik Oktayuni

{"title":"Effect of Solvent Type and Germination Time on The Level of Free Amino Acid and Peptides of Germinated Pigeon Pea (Cajanus cajan (L.) Millsp) Extract","authors":"K. Ratnayani, Ni Wayan Wisaniyasa, Ni Putu Wiwik Oktayuni","doi":"10.21776/ub.jpacr.2022.011.02.672","DOIUrl":"https://doi.org/10.21776/ub.jpacr.2022.011.02.672","url":null,"abstract":"Germination can activate the degradation of storage protein in legumes releasing peptides and free amino acids for seed growth. These compounds have many benefits in many fields, especially in food and health. This study aimed to determine the effect of solvent type and germination time on the level of free amino acids (FAA) and the level of peptides (MW < 10 kDa) of germinated pigeon pea extract. The extraction of free amino acids and the dissolved protein from germinated pigeon pea flour was carried out using two kinds of solvents, namely water, and 0.1 N HCl. The variation of germination times of pigeon pea seeds was carried out at 12, 24, 36, 48, 60, 72, 84, and 96 hours. The level of FAA was determined spectrophotometrically using the ninhydrin method after the deproteination step, while the level of peptides was determined spectrophotometrically using the biuret method. The results showed that using 0.1 N HCl as a solvent produced a higher level of FAA and peptides in the extract than using water. The increase of germination time can increase the level of FAA with the peak achieved in 36 hours. The increase of germination time can increase the level of peptides with the peak of peptides level achieved on 84 hours of germination. These results showed that seed germination is a potential method for producing free amino acids and peptides which accumulate at a specific time","PeriodicalId":22728,"journal":{"name":"The Journal of Pure and Applied Chemistry Research","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85207889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0