{"title":"「レーザー医療におけるレギュラトリーサイエンス」と「下肢静脈瘤血管内レーザー治療の進展」によせて","authors":"良望 黒川","doi":"10.2530/JSLSM.33.26","DOIUrl":"https://doi.org/10.2530/JSLSM.33.26","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"22 1","pages":"26-26"},"PeriodicalIF":0.0,"publicationDate":"2012-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84103553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"5-ALA 光線力学診断の問題点:蛍光輝度定量化は可能か,ポルフィリン蓄積機序は解明されたのか","authors":"宜永 梶本, 敏彦 黒岩","doi":"10.2530/JSLSM.32.143","DOIUrl":"https://doi.org/10.2530/JSLSM.32.143","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"18 1","pages":"143-148"},"PeriodicalIF":0.0,"publicationDate":"2011-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78815408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"「医療用光ファイバー, 周辺装置およびその応用技術」の特集によせて","authors":"祐司 松浦","doi":"10.2530/JSLSM.31.406","DOIUrl":"https://doi.org/10.2530/JSLSM.31.406","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"10 1","pages":"406-406"},"PeriodicalIF":0.0,"publicationDate":"2011-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88294601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inverse Monte Carlo法による光線力学療法前後の腫瘍組織の光学特性の算出","authors":"典広 本多, 隆哉 寺田, 卓也 南條, 克典 石井, 邦男 粟津","doi":"10.2530/JSLSM.31.115","DOIUrl":"https://doi.org/10.2530/JSLSM.31.115","url":null,"abstract":"光線力学療法(PDT)の治療計画において,生体組織内の光の侵達度や照射線量分布を定量的に把握することは,治療成績を向上させるために重要である.生体組織内の光の侵達度は,生体組織の光学特性である吸収係数 [mm-1],換算散乱係数 [mm-1]等により理解できる.一般的に,レーザー照射により生体組織の光学特性は変化する.そこで,我々は,PDT前後の腫瘍組織の光学特性を算出することを目的として基礎的検討を行った.Talaporfin Sodiumを用いたPDTをマウス皮下腫瘍モデルに対して行い,双積分球光学系とInverse Monte Carlo法を用いて波長350~1000nmにおける腫瘍組織の光学特性を算出した.PDT実施7日後,Talaporfin Sodiumの吸収極大波長664nmにおいて,換算散乱係数はPDT前に比べて0.64mm-1から1.24mm-1に増加し,結果,腫瘍組織への光の侵達度はPDT前に比べおよそ44%減少することが見積もられた.以上より,追加のレーザー照射によるPDTの際,PDT後の光の侵達度の減少を考慮し,レーザー照射条件を調整することが必要であることが示唆された.","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"22 1","pages":"115-121"},"PeriodicalIF":0.0,"publicationDate":"2010-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82640946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"「形成・美容皮膚科におけるレーザー治療」の特集によせて","authors":"宗男 宮坂","doi":"10.2530/JSLSM.31.29","DOIUrl":"https://doi.org/10.2530/JSLSM.31.29","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"19 1","pages":"29-29"},"PeriodicalIF":0.0,"publicationDate":"2010-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78631221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"泌尿器悪性腫瘍に対するPhotodynamic diagnosis(PDD)","authors":"豪泰 松山","doi":"10.2530/JSLSM.31.400","DOIUrl":"https://doi.org/10.2530/JSLSM.31.400","url":null,"abstract":"Photodynamic diagnosis (PDD)は泌尿器科領域では膀胱上皮内癌などの平坦病変を中心とした新しい診断法として発展してきた.筋層非浸潤性膀胱癌においてはメタアナリシス解析により,診断率の向上とそれに伴う残存腫瘍の減少による非再発率の向上が明らかとなった.これは,従来指摘されていた(腫瘍見落としによる)再発率の施設間格差を減少させ,膀胱がん治療の均てん化に寄与することが期待される.また他の泌尿器科腫瘍においても5-ALA経口投与による腎細胞がんや前立腺癌における術中外科的断端陽性の判定などに利用されるようになってきた.本総説では最近の筋層非浸潤性膀胱癌に対するPDDを用いた診断とPDD補助下経尿道的膀胱腫瘍切除術の治療成績について論文を紹介するとともに膀胱癌以外の泌尿器科腫瘍へのPDD応用の実例を紹介する.","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"4 1","pages":"400-405"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78887781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"「医工連携:医療レーザー発展への課題」特別解説特集に寄せて","authors":"邦男 粟津","doi":"10.2530/JSLSM.30.54","DOIUrl":"https://doi.org/10.2530/JSLSM.30.54","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"22 1","pages":"54-54"},"PeriodicalIF":0.0,"publicationDate":"2009-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89819231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DuraHeart^【○!R】 左心補助人工心臓の開発 : 何故米国で開発しなければならなかったか?","authors":"野尻 知里","doi":"10.2530/JSLSM.30.78","DOIUrl":"https://doi.org/10.2530/JSLSM.30.78","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"69 1","pages":"78-86"},"PeriodicalIF":0.0,"publicationDate":"2009-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84597237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"コンジローマ合併子宮頸部上皮内癌に対し光線力学療法(PDT)が著効した1例","authors":"清 三宅, 賢治 吉田, 岡本 三四郎, 司 秋谷, 真也 中野, 優紀 坂本, 美夫 天神, 西村 隆一郎, 忠夫 田中","doi":"10.2530/JSLSM.30.26","DOIUrl":"https://doi.org/10.2530/JSLSM.30.26","url":null,"abstract":"HPVは,そのDNAタイプにより,子宮頸部にコンジローマのような良性病変や,子宮頸癌のような悪性病変を引き起こすことが知られている.コンジローマの治療法は内科的治療・外科的治療であるが,光線力学療法(PDT)による治療効果については現在のところ明らかではない.今回,コンジローマ合併子宮頸部上皮内癌に対しPDTが著効した1例を経験したので報告する.34歳,子宮頸部病変にて精査・加療目的に受診.同部位にコンジローマおよび上皮内癌を認めコンジローマ合併上皮内癌と診断.HPVジェノタイピング(アンプリコア・リニアアレイ法®)にて6型と16型の重複感染を認めた.家族および本人から十分なインフォームドコンセントを得てPDTを施行した.治療6ヶ月後,組織診・HPV含め異常所見は消失した.本症例は,高リスクと低リスクHPVが子宮頸部に同時に感染したため,同部位にコンジローマおよび上皮内癌が生じたものと考えられた.PDTはコンジローマ合併症例に対しても有効な治療法であることが示唆された.","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"49 1","pages":"26-29"},"PeriodicalIF":0.0,"publicationDate":"2009-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76881604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}