The Journal of the Association of Physicians of India最新文献

{"title":"Influence of Problem-based Learning Method on Learning Outcomes in Medical Curriculum.","authors":"Saara Banu Epm, Yazhini Karuppiah, K Bhuvaneswari","doi":"10.59556/japi.73.1079","DOIUrl":"10.59556/japi.73.1079","url":null,"abstract":"<p><strong>Introduction: </strong>Problem-based learning (PBL) is a student-centered learning approach in which students learn through analyzing and solving problems.</p><p><strong>Justification: </strong>Traditional teaching program is in the form of a dictated lecture and is teacher-centered. A larger number of topics can be covered without active student participation. In PBL, which promotes deep learning, students learn to justify their knowledge with the help of cognitive skills and complex thinking.</p><p><strong>Methods: </strong>This retrospective study was done after obtaining Institutional Human Ethics Committee (IHEC) approval. Data collected from three internal assessment examinations (IAEs) written between the period of January 2017 and August 2017 by 151 students pursuing second-year MBBS training in the Department of Pharmacology. Examination papers for second-year MBBS students contain questions such as short notes, ultrashort, and PBL.</p><p><strong>Results: </strong>Wilcoxon Mann-Whitney test analysis of IAE-1 with IAE-2 and IAE-1 with IAE-3 in SPSS software gave <i>p</i>-value-0.393 and 0.020, respectively. Using analysis of variance (ANOVA), IAE-2 with PBL and IAE-3 with PBL showed <i>p</i>-value 0.001, which was statistically significant. There was an increase in the pass percentage [number of students who scored 40 and above in IAE-3 (with PBL) when compared to IAE-1 (without PBL)].</p><p><strong>Conclusion: </strong>This audit showed definite knowledge improvement by the students using PBL as a tool along with a traditional teaching program.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"32-34"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newer Therapies for Osteoporosis: A Systematic Review.","authors":"Parthajit Das, Mohit Goyal, Debaditya Roy, Vinod Ravindran","doi":"10.59556/japi.73.1084","DOIUrl":"10.59556/japi.73.1084","url":null,"abstract":"<p><strong>Objective: </strong>The current management of osteoporosis has several unmet needs. Consequently, the newer and upcoming agents and targets are being expectantly looked at. We aim to appraise the evidence examining the efficacy of the newer therapies for the management of osteoporosis.</p><p><strong>Methods: </strong>Scopus, Embase, and MEDLINE databases were screened from January 2013 to December 2023 to identify clinical trials that evaluated the efficacy of newer agents for the treatment of osteoporosis in men and postmenopausal women (PMO). Changes in bone mineral density (BMD) and incidences of vertebral fractures (VFs) and nonvertebral fractures (NVFs) or relative risk reduction (RRR) for VF and NVF were retrieved. The Oxford quality scoring system was applied to evaluate the methodological quality of the included clinical trials.</p><p><strong>Results: </strong>Eighteen randomized controlled trials (RCTs) that had enrolled 22,868 PMO and 473 male participants were included. Anabolic agents abaloparatide and romosozumab exhibited significant BMD gain and relative RRR for fractures and greater efficacy than teriparatide. Blosozumab was reported to exhibit substantial BMD gains. The efficacy of a sequential therapeutic strategy with anabolic agent followed by antiresorptive agents was superior to the reverse sequence.</p><p><strong>Conclusion: </strong>Newer therapies for osteoporosis exhibited significant BMD gain and fracture risk reduction in men and PMO. The newer anabolic agents demonstrated greater efficacy than any of the previously available therapeutic options.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"67-76"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Metrics in Hospitalized Male Patients with Acute Coronary Syndrome.","authors":"Meenaxi Sharda, Nisa Susan Thomas, Yogesh Kumar Bareth, Setu Jain, Dheeraj Krishna, Hemant Vimlani, Arjun Deepak Tanup","doi":"10.59556/japi.73.1080","DOIUrl":"10.59556/japi.73.1080","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery disease (CAD) is the leading cause of mortality globally, with a pronounced impact in India. Acute coronary syndrome (ACS), which includes unstable angina (UA), non-ST-elevation myocardial infarction (NSTEMI), and ST-elevation myocardial infarction (STEMI), is a manifestation of CAD. In 2010, the American Heart Association (AHA) introduced Life's Simple 7 (LS7) to improve cardiovascular health (CVH) by emphasizing disease prevention and lifestyle changes. This study aims to find the prevalence and distribution of LS7 metrics in hospitalized male patients with ACS compared to healthy individuals.</p><p><strong>Methods: </strong>An observational case-control study was conducted at Government Medical College, Kota, between December 2022 and 2023, involving 50 male cases of ACS and 100 male controls, in the age-group 21-50. The Life's Simple 7 score was calculated by recording blood pressure, fasting blood glucose, total cholesterol, body mass index (BMI), diet, physical activity, and smoking/tobacco use. Scores were categorized into three groups, with 10-14 having ideal CVH, 5-9 as intermediate, and 0-4 as poor. Data were analyzed using SPSS 25.0, employing Chi-square, ANOVA, and calculating odds ratios and relative risk.</p><p><strong>Observations: </strong>In this study, ACS cases had a mean LS7 score of 7.68, lower than the control group's 9.39, showing poorer CVH. High prevalence rates of hypertension (28%), diabetes (12%), and dyslipidemia (4%) were significant contributors to ACS, with odds ratios of 2.2, 1.94, and 1.94, respectively, and relative risks of 1.67, 1.83, and 1.83. Smoking was highly prevalent among ACS cases (96%), with an odds ratio of 12.77 and a relative risk of 1.47. Ideal BMI was present in only 48% of cases, with an odds ratio of 2.5 and a relative risk of 2.29. STEMI (78%) was prevalent among ACS cases, with single-vessel disease most common in angiographic findings.</p><p><strong>Conclusion: </strong>The ACS cases studied had suboptimal CVH metrics compared to controls. These findings highlight the critical role of healthy lifestyles and managing modifiable risk factors in reducing ACS incidence and improving CVH outcomes.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"21-24"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Pattern of Transfusion Reactions and its Association with Blood and its Components in a Tertiary Care Hospital.","authors":"Sonia Gupta, Rajesh Kumar, Shruti Kakkar","doi":"10.59556/japi.73.1081","DOIUrl":"10.59556/japi.73.1081","url":null,"abstract":"<p><strong>Objectives: </strong>Transfusion medicine has made substantial progress in research, and blood transfusions are now safer than ever before. Still, the inherent risk of transfusion reactions (TRs) continues with transfusion of blood and blood components. The study was designed to analyze the incidence and nature of TRs reported in the blood center.</p><p><strong>Materials and methods: </strong>A retrospective review of all TRs reported to the blood center was retrieved from incident reporting forms from January 2020 to December 2022. All acute transfusion reactions (ATRs) were tabulated and analyzed by the blood transfusion officer and classified according to National Blood Transfusion guidelines. Data were described in terms of range, mean ± standard deviation (± SD), median (IQR), frequencies (number of cases), and relative frequencies (percentages), as appropriate.</p><p><strong>Results: </strong>A total of 1,65,121 blood and blood components were issued, and ATRs reported were 296 (0.18%). The median (IQR) age of the patient was 45-60, with M:F of 1.3:1. Febrile nonhemolytic transfusion reactions (FNHTR) 151 (51%) were the most common ATRs, followed by allergic TRs 111 (37.5%). The estimated risk of transfusion reaction per 1,000 units was highest with whole blood (WB) 3.84 (<i>p</i> = 0.038), followed by packed red blood cells (PRBCs) 2.85 (<i>p</i> = 0.001), and single donor platelet (SDP) 1.47 (<i>p</i> = 0.571). The most common symptoms observed were fever 31.8%, followed by chills 28.7%, and rashes 27.4%. FNHTR (27/151) 17.8% were reported most frequently from gastroenterology, allergic (26/111) 23.4% from emergency, and delayed hemolytic transfusion reactions (DHTR) (9/9) 100% from thalassemia day care center (<i>p</i> = 0.001).</p><p><strong>Conclusion: </strong>The overall incidence of TRs was 0.18%. The incidence of actual TRs remains underestimated due to lack of awareness regarding TRs among healthcare professionals.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"35-39"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian Blood Pressure Profile and Associated Cardiovascular Risk Factors in Prehypertensive Patients and Its Relationship with Urinary Albumin-to-Creatinine Ratio.","authors":"Jaldu Krishna Pavan, Ashok Kumar, Gutti Prasanth, Shubha Laxmi Margekar, Shivani Bansal","doi":"10.59556/japi.73.1067","DOIUrl":"https://doi.org/10.59556/japi.73.1067","url":null,"abstract":"<p><strong>Background: </strong>Prehypertension is characterized by a systolic blood pressure (SBP) ranging from 120 to 139 mm Hg and a diastolic blood pressure (DBP) between 80 and 89 mm Hg, acting as a precursor to hypertension and potentially increasing cardiovascular risks. This study investigates the circadian patterns of blood pressure (BP), dipper status, and associated cardiovascular risk factors in prehypertensive individuals, with a particular focus on the relationship with the urinary albumin-to-creatinine ratio (UACR) as a marker of kidney and vascular health.</p><p><strong>Objective: </strong>To assess the circadian rhythm of BP in prehypertensive patients and examine its relationship with UACR and other cardiovascular risk factors.</p><p><strong>Methods: </strong>In this research involving systematic observation, a total of 101 participants were included, 57.4% of whom were identified as prehypertensive. Prehypertensive participants were grouped into \"dippers\" or \"nondippers\" based on a nocturnal BP reduction threshold of greater than or <10%, respectively. UACR, high-sensitivity C-reactive protein (Hs-CRP), lipid profiles, and additional biochemical parameters were measured. Statistical analysis included <i>t</i>-tests and analysis of variance (ANOVA) were utilized to examine associations.</p><p><strong>Results: </strong>Prehypertensive subjects demonstrated significantly higher mean 24-hour SBP and DBP than normotensive controls (<i>p</i> < 0.001). Dipper status was identified in 55.2% of prehypertensives, with nondippers exhibiting elevated nighttime SBP and DBP (<i>p</i> < 0.001). UACR and nondipper status were found to be significantly correlated (<i>p</i> = 0.034), with nondippers also displaying elevated Hs-CRP levels, indicating greater systemic inflammation.</p><p><strong>Conclusion: </strong>Circadian BP variability and dipper status in prehypertensive patients correlate with UACR and Hs-CRP levels, suggesting that nondippers may be at increased cardiovascular risk. Ambulatory blood pressure monitoring (ABPM) offers valuable insights into early hypertension risk and can aid in identifying prehypertensive individuals requiring closer monitoring and intervention.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"25-30"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Dehydration and Use of Oral Electrolytes in Adults and Older adults with Nondiarrheal Conditions: A Retrospective, Real-world, Database Study.","authors":"Sumit Bhatia, Manoj Chawla, Priti Thakor, Harshad Malve, Amol Patil","doi":"10.59556/japi.73.1088","DOIUrl":"10.59556/japi.73.1088","url":null,"abstract":"<p><strong>Introduction: </strong>Dehydration due to nondiarrheal conditions often goes underrecognized. Physicians rely on the guidelines for the treatment of diarrheal dehydration to treat nondiarrheal dehydration. However, treatment of nondiarrheal dehydration requires fluid, electrolyte, and energy (FEE) drinks with additional energy, which help overcome the FEE deficits created due to hypermetabolic response to such conditions.</p><p><strong>Methodology: </strong>Anonymized and aggregated data retrieved from the HealthPlix electronic medical record (EMR) database was used to understand the usage of oral electrolytes in nondiarrheal conditions in nondiabetic patients and their effect on the resolution of fever and respiratory tract infection (RTI).</p><p><strong>Results: </strong>There was a significant gap between the number of patients with documented dehydration and those prescribed oral electrolytes. ORSL^® emerged as the top prescription choice for multiple conditions and symptoms among the products studied. Recovery from fever was relatively faster in the case of the patients prescribed oral electrolytes. The proportion of patients resolved from RTI was higher for the oral electrolyte arm. This suggests the crucial role of oral electrolytes to support recovery from nondiarrheal conditions.</p><p><strong>Conclusion: </strong>Dehydration in nondiarrheal conditions should be appropriately examined and documented in the prescriptions. There exists a need to highlight the importance of prescribing oral electrolytes with standard medical care to benefit the patients.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8S","pages":"11-15"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preface.","authors":"Mangesh Tiwaskar","doi":"10.59556/japi.73.1086","DOIUrl":"10.59556/japi.73.1086","url":null,"abstract":"<p><p>This special issue of the \"Journal of the Association of Physicians of India\" focuses on an underappreciated aspect of patient care: dehydration in nondiarrheal illnesses, particularly in diabetic nondiabetic, adult, and elderly populations as well as highlight ways to enhance oral rehydration therapy utilization in India.¹ Dehydration in acute nondiarrheal diseases, often resulting from reduced intake or increased fluid losses, can lead to critical deficits in fluid, electrolytes, and energy (FEE).^2,3 Oral FEE supplementation, when used as an adjuvant to standard care, has shown clinical benefits in improving hydration and energy levels in earlier small studies, particularly in patients with fever, general weakness, and metabolic conditions such as diabetes.^2-6 The reported studies in this issue delve into the clinical consequences of dehydration, its underrecognition in certain populations, and the therapeutic role of oral FEE solutions like ORSL® in supporting patient recovery, especially in diabetic and elderly individuals.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8S","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multispecialty Consensus on Individualized Treatment Strategies for Hypertension Phenotypes and Comorbidities.","authors":"Gurpreet S Wander, Kamlesh Tewary, A Muruganathan, Agam C Vora, Girish Mathur, Chenniappan Meenakshisundaram, Narinder P Singh, Anup Barman, Munish Prabhakar, Nandini Chatterjee, Sujoy Ghosh, Puneet Saxena, Nihar Mehta, Jayanta K Panda, Sekhar Chakraborty, G D Ramchandani, Debaprasad Chakraborty, Saikat Datta, Mrinal K Roy, Amit A Saraf, Dwijen Das, Chandni Radhakrishnan, Devendra P Singh, M Ravikeerthy, Sandip Mitra","doi":"10.59556/japi.73.1092","DOIUrl":"10.59556/japi.73.1092","url":null,"abstract":"<p><p>Hypertension (HTN) remains a leading contributor to global morbidity and mortality, often coexisting with major comorbidities such as diabetes, chronic kidney disease (CKD), coronary artery disease (CAD), heart failure (HF), and obesity. In India, a significant proportion of hypertensive individuals remain undiagnosed or inadequately treated. This multispecialty consensus provides comprehensive, evidence-based recommendations for individualized HTN management tailored to specific phenotypes and comorbidities. Developed through structured expert panel discussions and a review of international and national guidelines, the consensus emphasizes out-of-office blood pressure (BP) monitoring, phenotype recognition (e.g., white-coat, masked, nocturnal HTN), and early detection of target organ damage. The document outlines practical algorithms and a therapeutic wheel to guide antihypertensive therapy based on patient-specific factors, promoting use of angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARBs), calcium channel blockers (CCBs), beta-blockers (BB), and diuretics, as per clinical context. Special considerations are provided for managing HTN in young adults, patients with tachycardia, stroke, and respiratory disorders. The consensus also advocates for lifestyle modifications, treatment adherence, and multidisciplinary care to improve BP control and long-term outcomes. By promoting a holistic, patient-centered approach, this consensus aims to bridge gaps in clinical practice and standardize the management of HTN in diverse healthcare settings.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"77-84"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Hypertension in Young Adults in Punjab.","authors":"Manpreet Singh Brar, Meghna Gupta, Vitull K Gupta, Keshav Garg","doi":"10.59556/japi.73.1065","DOIUrl":"10.59556/japi.73.1065","url":null,"abstract":"<p><strong>Introduction: </strong>India has shown dramatic increase in noncommunicable diseases (NCDs), so much so that about 70% of the overall mortality is estimated to be because of NCDs. Young adults <35 years of age constitute 65%, a significant section of Indian population, but there is paucity of studies exploring prevalence of HTN among young adults in India, especially in Punjab. So, the present study was conducted to know the prevalence of HTN among young adults in Punjab.</p><p><strong>Materials and methods: </strong>This observational study was conducted as part of a global blood pressure (BP) screening program, after approval from Institutional Ethics Committee. Subjects of 18-80 years were included after verbal informed consent. Data obtained was analyzed as per the standard statistical method, and Chi-squared test was applied.</p><p><strong>Results: </strong>A total of 24,685 participants completed the study including 43.5% young adults. The prevalence of HTN in young adults was 9.2 and 18.8% in older adults. About 71.8% hypertensive young adults were overweight or obese. Males demonstrated 16.7% prevalence of HTN as compared to 12.3% in females, whereas in young adults 28.4% females had HTN as compared to 26.6% males.</p><p><strong>Conclusion: </strong>Present study documents increase in prevalence of HTN among young adults and its association with overweight and obesity necessitating initiation of HTN prevention and control strategies, especially focused on young adults.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"44-49"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoding \"Ghabrahat\": A Cross-sectional KAP Study of Healthcare Professionals' Understanding and Management of a Complex South Asian Medical Term.","authors":"Rahul Garg, Anmol Thakre","doi":"10.59556/japi.73.1076","DOIUrl":"10.59556/japi.73.1076","url":null,"abstract":"<p><strong>Background: </strong>In South Asian healthcare settings, certain symptoms described in local languages create unique challenges in medical practice. \"Ghabrahat\" is a commonly used term that lacks standardization in medical terminology and presents difficulties in translation and interpretation. This study aimed to comprehensively assess the knowledge, attitudes, and practices (KAP) regarding \"ghabrahat\" among healthcare professionals.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted among 107 healthcare professionals, including faculty members and postgraduate trainees, across multiple tertiary care centers. A structured questionnaire was used to evaluate their understanding, perceptions, and clinical approaches regarding \"ghabrahat\" as a medical term.</p><p><strong>Results: </strong>Of the 107 participants, 105 (98.1%) had encountered the term during their medical practice. The majority (77.6%) believed that \"ghabrahat\" requires further medical investigation, and 94.4% considered it treatable/manageable. Significant associations were found with cardiovascular (86%) and psychological (73.8%) systems. Gender differences in perception were noted by 67.2% of participants, while 88.8% believed that comorbidities influence its presentation. Notably, 54.2% of participants reported encountering mortalities directly attributed to \"ghabrahat.\"</p><p><strong>Conclusion: </strong>While \"ghabrahat\" is widely recognized among healthcare professionals, there exists substantial variation in its interpretation, perceived severity, and management approaches. This study highlights the urgent need for standardization in understanding and approaching this commonly reported symptom in South Asian medical practice.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 8","pages":"40-42"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}