Infectious Diseases Diagnosis & Treatment最新文献

{"title":"Profile of Critical COVID-19 Illness in Children During the Second and Third Wave of the Pandemic: A Single Center Study from South India","authors":"Sangeeta V Budur, S. Thyagarajan","doi":"10.29011/2577-1515.100221","DOIUrl":"https://doi.org/10.29011/2577-1515.100221","url":null,"abstract":"Aims : To describe the clinical characteristics of children with critical COVID-19 illness from a single tertiary referral center during the second and third waves to understand the burden of critical COVID-19 illness in children which may guide preparedness in terms of resources, training, and services. Methods: A prospective observational study of critical COVID-19 children under the age of 18 years admitted to a ten-bedded PICU during the second wave (April-July 2021) and third wave (December-February 2022) of the COVID-19 pandemic. We categorized the children into 1) Acute COVID-19 infection and 2) Multi-inflammatory Syndrome in Children - MISC (post COVID-19/MISC secondary to acute COVID-19 infection). Demographic data, clinical data, investigations, treatment given, and outcome measures were studied. Results: Seventy-six critical COVID-19 illness admissions occurred with male preponderance. Sixty-two (81%) children presented with acute COVID-19 illness, 20 in the second wave and 42 in the third wave. Respiratory symptoms (85% vs 30%) predominated during the second wave and neurological symptoms (35% vs 20%) during the third wave. Critical care interventions were higher in the second wave. Neurological comorbidity led to mortality (5% vs 2%). MISC was seen in fourteen (19%) children. Intravenous immunoglobulin and methylprednisolone were given more during the third wave (80% vs 11%). One child in each wave died (11 % vs 20%). Conclusions: The clinical profile of children with critical COVID-19 illness has been changing and becoming progressively complex and atypical during each wave with significant morbidity but with good clinical outcomes/recovery rate.","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130819793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV and Covid 19 Coinfection, A Local Perspective: A Retrospective Study from Qatar","authors":"H. Alsoub, A. Alkhal, M. Maslamani, J. Nader","doi":"10.29011/2577-1515.100220","DOIUrl":"https://doi.org/10.29011/2577-1515.100220","url":null,"abstract":"Background : People living with HIV might be at an increased risk of SARS-CoV-2 infection or severe COVID-19 disease. In this report we aim to study patients with HIV/COVID 19 coinfection seen in Qatar and examine the effects of this coinfection on disease course and attempt to identify factors that may be associated with severe disease. We also attempt to compare our finding with that of a previous study conducted in Qatar in view of the emergence of new SARS CoV-2 variants and the widespread use of COVID 19 vaccine. Method : Review of the medical records of all HIV infected patients who developed COVID 19 infection during the period between 27 th February 2020 and 31 December 2022. Results : Among the 329 HIV infected patients who were living in Qatar during the study period we identified 136 patients with HIV/COVID 19 coinfection. 90 were Qatari and the rest were from other nationalities. 117 patients were males and 19 were females with a median age of 34 [IQR 28-59] years. 111 were known to be HIV infected before COVID 19 diagnosis and 25 were found to have HIV infection at the time of COVID 19 diagnosis or shortly after. 50 patients developed COVID 19 infection either before receiving SARS CoV-2 vaccine or in less than 14 days after the first vaccine dose and after a median of 246 days from last vaccine dose in the 86 vaccine recipients. Reinfection was relatively common occurring in about 9% of patients, however occurring after a median of 332 and 267 days from previous infection and last vaccine dose respectively. The disease was mild with hospital admission. There was no disease related mortality. Conclusion : The clinical manifestations of patients with HIV/COVID 19 coinfection seen in Qatar were similar to that reported by others, however, they were younger with male preponderance and is mostly mild to moderate in severity. Most infections occurred in the third year of the study (57%) when the Omicron variant was the predominant strain circulating in Qatar. Most infections occurred either in unvaccinated patients, within 14 days after the first dose or after a long period form the last vaccine dose. The outcome was excellent with no disease related mortality.","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"40 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122754777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long Covid Patients Successfully Treated by Means of Heparin-Mediated Extracorporeal LDL Precipitation (H.E.L.P.) Apheresis","authors":"Beate Roxane, Jaeger, Hayley Emma Arron, R. M. Booyens, Christiane Kappert, J. Helden, Maud Weimer, O. Weingärtner, Rainer Seibel, Franz Reichl, Asad Khan, D. Seidel, Lipidzentrum Jaeger, Mülheim Nordrhein, an der Ruhr, Germany","doi":"10.29011/2577-1515.100216","DOIUrl":"https://doi.org/10.29011/2577-1515.100216","url":null,"abstract":") Case Report: Long Covid Patients Successfully Treated by Means of Heparin-Mediated Extracorporeal LDL Precipitation (H.E.L","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133317596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curcumin and Colistin are Synergistic in Inhibiting the Growth and Biofilm Formation of Pseudomonas aeruginosa Isolated from Environmental Sample","authors":"","doi":"10.29011/2577-1515.100218","DOIUrl":"https://doi.org/10.29011/2577-1515.100218","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126863903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Diagnostic Accuracy of Rapid SARS-CoV-2 Antigen Detection Kits Used in Public Testing Centers in Mongolia","authors":"","doi":"10.29011/2577-1515.100214","DOIUrl":"https://doi.org/10.29011/2577-1515.100214","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132023681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Native Joint Septic Arthritis Due to Rothia mucilaginosa: A Case Report and Literature Review","authors":"","doi":"10.29011/2577-1515.100209","DOIUrl":"https://doi.org/10.29011/2577-1515.100209","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121752007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Observational Study on The Effect of Steroid Use in Covid-19 Patients","authors":"","doi":"10.29011/2577-1515.100208","DOIUrl":"https://doi.org/10.29011/2577-1515.100208","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130050504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Mixed Plasmodium falciparum and Plasmodium malariae Infection in a 1 Year 04 Months Old Child in Western Region, Côte d`Ivoire","authors":"","doi":"10.29011/25771515.100206","DOIUrl":"https://doi.org/10.29011/25771515.100206","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131266928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of Anemia in Children Less Than 7 Years Old in the Western Region (Man) of Côte D`Ivoire","authors":"","doi":"10.29011/2577-1515.100205","DOIUrl":"https://doi.org/10.29011/2577-1515.100205","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121159497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Minority Representation through COVID-19 Community Research Partnership","authors":"","doi":"10.29011/2577-1515.100204","DOIUrl":"https://doi.org/10.29011/2577-1515.100204","url":null,"abstract":"","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"230 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123030486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}