Infectious Diseases Diagnosis & Treatment最新文献

A Pediatric Case of Trimethoprim/ Sulfamethoxazole Associated Aseptic Meningitis 一个与曲安奈德/磺胺甲噁唑相关的无菌性脑膜炎儿科病例

Infectious Diseases Diagnosis & Treatment Pub Date : 2024-03-15 DOI: 10.29011/2577-1515.100255

引用次数: 0

Kinetics of Cytokines and Anti-SARS-CoV-2 Spike Glycoprotein S1 IgM and IgG1 in COVID-19 Infected Patients in Togo 多哥 COVID-19 感染者体内细胞因子和抗 SARS-CoV-2 Spike 糖蛋白 S1 IgM 和 IgG1 的动力学特征

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-12-22 DOI: 10.29011/2577-1515.100242

引用次数: 0

Blood Groups (ABO/Rh) and Sociodemographic and Clinical Profile Among Patients with Leprosy in Angola 安哥拉麻风病人的血型（ABO/Rh）及社会人口学和临床概况

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-12-20 DOI: 10.29011/2577-1515.100247

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Profile of Chlamydia trachomatis and Treponema pallidum Infections in Patients Aged from 18 To 50 Years Old: Cases of CHU-RN 18至50岁患者的沙眼衣原体和苍白螺旋体感染概况：中国人民大学病例

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-11-21 DOI: 10.29011/2577-1515.100240

Tanssoube Ndeune, Tariam Djibangar, D. Kimassoum, Bessimbaye Nadlaou, Bakaranga-Via Issakou, B. B. Otchom, A. Tidjani

引用次数: 0

Myroides Spp: An Emerging Uro-pathogen in Catheterized Patient Isolated in Tertiary Care Hospital, New Delhi: A Case Report Myroides Spp：新德里三级医院导尿患者中分离出的一种新出现的泌尿系统病原体：病例报告

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-11-17 DOI: 10.29011/2577-1515.100241

Iram Rafique, Sanchita Tuteja, M. Chaudhary, Rahul Lal, Sonal Saxena

{"title":"Myroides Spp: An Emerging Uro-pathogen in Catheterized Patient Isolated in Tertiary Care Hospital, New Delhi: A Case Report","authors":"Iram Rafique, Sanchita Tuteja, M. Chaudhary, Rahul Lal, Sonal Saxena","doi":"10.29011/2577-1515.100241","DOIUrl":"https://doi.org/10.29011/2577-1515.100241","url":null,"abstract":"Introduction: We are presenting a case report of urinary tract infection caused by an emerging pathogen ( Myroides spp.) in an immunocompetent patient. They are low grade pathogen but can cause serious infections in immunocompromised patients. Background: Myroides spp. were traditionally classified as Flavobacterium spp., which are Gram negative, non-fermentative and non-motile bacteria. Myroides spp. are commonly present in environment, sewage, food and soil. An increasing number of infections such as urinary tract infections, sepsis and skin and soft tissue infections, caused by these microorganisms has been reported. Due to its multidrug resistant nature, it is important to correctly identify Myroides spp. in order to choose the best treatment regimen. Case: A 62yr male resident of Delhi presented to Surgery Emergency Department of our hospital with complaints of recurrent episodes of retention of urine and heaviness in lower abdominal. Patient had history of repeated catheterisation with BPH (Benign Prostate Hypertrophy). Subsequently, urine sample was inoculated on Blood Agar and MacConkey’sAgar and incubated for 24 hours at 37ºC. After the incubation, a pure culture with a colony count of >100,000 CFU/ml of a non-lactose fermenting colony was identified as Myroides spp. The patient was successfully treated with Aztreonam after antibiotic susceptibility testing confirmed its susceptibility. Conclusions: This case report brings to light the importance of a newly emerging atypical multidrug resistant uro-pathogen in an immunocompetent individual.","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139263983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biobetter Versions of Recombinant Human IFN-a2b for the Treatment of Viral Infections 用于治疗病毒感染的重组人 IFN-a2b 生物复合物

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-10-05 DOI: 10.29011/2577-1515.100236

引用次数: 0

Deciphering the Structural and Functional Properties of ABC-F ATPases ABC-F三磷酸腺苷酶的结构和功能特性解读

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-07-31 DOI: 10.29011/2577-1515.100225

Chiranjeet Saha, Sujata Saha, Asmita Chakraborty, A. Dirisala, A. Maity, P. Bhowmik, Kunal Sikder, Soumyananda Chakraborti, A. Basu

引用次数: 0

Half Reaction Volume Optimization of Viral Load Real Time PCR: Lessons, Challenges, and Experience in A Resource Limited Setting 病毒载量实时PCR的半反应量优化:在资源有限的情况下的教训、挑战和经验

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-07-27 DOI: 10.29011/2577-1515.100226

Pooja Pandey, Aparna Pandey, J. Taneja, Sanchi Kashyap, R. Gupta, Priti Agarwal, Asim Das, Anil K Pandey, M. Rajiv, Professor Gupta

{"title":"Half Reaction Volume Optimization of Viral Load Real Time PCR: Lessons, Challenges, and Experience in A Resource Limited Setting","authors":"Pooja Pandey, Aparna Pandey, J. Taneja, Sanchi Kashyap, R. Gupta, Priti Agarwal, Asim Das, Anil K Pandey, M. Rajiv, Professor Gupta","doi":"10.29011/2577-1515.100226","DOIUrl":"https://doi.org/10.29011/2577-1515.100226","url":null,"abstract":"Quantitative polymerase chain reaction (qPCR) is a powerful tool for gene expression analysis. However, qPCR is expensive test however, optimizing the assay can be challenging, especially when working with limited amounts of Nucleic acid. This study aimed to evaluate and optimize half reaction qPCR approach for the detection and quantitation of Hepatitis B, C and human CMV. Methods: The reaction efficiency using half volumes of the RT-qPCR assay were evaluated. Comparison and stratification of Ct values between standard and half reactions of Hepatitis B, Hepatitis C and CMV positive samples was evaluated. Results: The qPCR efficiencies of half reaction were 100.9 %, 101.2% and 105.7% of Hepatitis B viral load, Hepatitis C viral load, CMV viral load respectively. The R2 for standard reaction was found to be 0.98, 1 and 1 for all the three PCR assessed as compared to R2 half reactions which was 1. Conclusions: Quantitative polymerase chain reaction (qPCR) is a powerful tool for gene expression analysis. Utilization of half volumes of the RT-qPCR assay was optimized and validated in this article. We explored the benefits and considerations of this optimization strategy in Hepatitis B, Hepatitis C and CMV viral load assays. The use of the RT-qPCR half-reaction proved feasible and economic for the detection of the same.","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128743527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unusual Cluster of Roseomonas mucosa Cases in a Hospital System: Related or Not? 医院系统中罕见的玫瑰单胞菌粘膜病例群:是否相关?

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-07-14 DOI: 10.29011/2577-1515.100222

E. Hilt, J. Dale, Bradley Craft, P. Ferrieri

引用次数: 0

Leptospirosis in the Tel Aviv District, Israel, 2016-2022

Infectious Diseases Diagnosis & Treatment Pub Date : 2023-07-07 DOI: 10.29011/2577-1515.100219

R. Sheffer, M. Savion, N. Nuss, Z. Amitai, Matanelle, Salama

{"title":"Leptospirosis in the Tel Aviv District, Israel, 2016-2022","authors":"R. Sheffer, M. Savion, N. Nuss, Z. Amitai, Matanelle, Salama","doi":"10.29011/2577-1515.100219","DOIUrl":"https://doi.org/10.29011/2577-1515.100219","url":null,"abstract":"Background: Leptospirosis is a bacterial zoonosis with a wide range of presentation, from unspecific and mild symptoms, to a more severe form of disease, which can sometimes be fatal. In Israel, leptospirosis is endemic with occasional outbreaks, including a nationwide outbreak in 2018 of approximately 600 cases. The aim of this study is to describe the epidemiologic, clinical and laboratory characteristics of leptospirosis in the Tel Aviv (TA) District, Israel between 2016-2022. Methods: We retrospectively analyzed all leptospirosis cases among residents of the TA District, Israel, during 2016-2022. Leptospirosis is a notifiable disease by law. An epidemiologic investigation is effectuated for each notified case by a trained nurse. Clinical data were obtained from patients’ clinical files. Results: A total 130 patients with leptospirosis were reported in the TA district between 2016-2022 (rates from 0-7.3 per 100,000 population per year). Most cases were men (n=109, 84%). Hospitalization was required for 40 (31%) cases; no deaths were reported. Among all cases, 78 (60%) were from the Ultra-orthodox city of Bnei Brak, 6 (5%) were workers without legal residency. Common sources of exposure included freshwater recreational activities (85% cases) and exposure to rodents (8% cases) Leptospira serovars were found to be associated with different sources of exposures: L. pomona was associated with exposures to freshwater recreational activities; L. Icterohemorrhagie, L. Sejreo Bratislava and L. Burgas were associated with exposure to rodents. Conclusion: More accessible diagnostic methods should be developed to better recognize the prevalence of leptospirosis and its burden, taking into account clinical symptoms as well as sources of exposures. This should enable adequate treatment and better control of potential reservoirs of leptospirosis and reduce the impact on vulnerable populations, such as residents of areas of lower socio-economic status.","PeriodicalId":226174,"journal":{"name":"Infectious Diseases Diagnosis & Treatment","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129211043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infectious Diseases Diagnosis &amp; Treatment最新文献

Infectious Diseases Diagnosis & Treatment最新文献