The Japanese journal of surgery最新文献_第4页

Clinical significance of P-glycoprotein expression analyzed by immunohistochemical staining in cancer tissues. 免疫组化染色分析肿瘤组织p -糖蛋白表达的临床意义。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02471002

R Kim, N Hirabayashi, M Nishiyama, K Aogi, T Toge

引用次数: 1

Recurrent valvular pneumoperitoneum caused by a minute gastric ulcer--a case report. 一分钟胃溃疡致复发性瓣膜性气腹1例。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470997

S Imabun, M Miyata, Y Tanaka, T Hashimoto, T Yamaguchi, S Sunada, T Kitagawa, Y Kawashima

引用次数: 4

Esophageal reconstruction using microvascular anastomosis to the thoracoacromial artery and cephalic vein. 胸肩峰动脉、头静脉微血管吻合食管重建术。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470987

H Fujita, Y Inoue, T Kakegawa, H Yamana, G Shirozu, T Minami, Y Tai

{"title":"Esophageal reconstruction using microvascular anastomosis to the thoracoacromial artery and cephalic vein.","authors":"H Fujita, Y Inoue, T Kakegawa, H Yamana, G Shirozu, T Minami, Y Tai","doi":"10.1007/BF02470987","DOIUrl":"https://doi.org/10.1007/BF02470987","url":null,"abstract":"For reconstruction of the pharynx and cervical esophagus following pharyngolaryngoesophagectomy, free gut transfer revascularized to such cervical vessels as the cervical transverse artery and external jugular vein is commonly performed. However, for reconstruction of the esophagus in the cervicothoracic junction or anterior to the chest wall, using the cervical vessels has more disadvantages than using the vessels in the chest wall. Thus, we developed a method of using the throracoacromial artery and cephalic vein for vascular anastomoses of a free jejunal graft and report herein our results in six cases. Three of these cases underwent reconstruction for an esophageal defect anterior to the chest wall, while the other three underwent reconstruction of the thoracic esophagus using a colonic pedicle graft. Satisfactory results were obtained in five of the six cases. Therefore, we recommend the use of the thoracoacromial artery and cephalic vein in vascular anastomoses during a free gut transfer or colonic pedicle graft for reconstruction of the esophagus anterior to the chest wall.","PeriodicalId":22610,"journal":{"name":"The Japanese journal of surgery","volume":"21 5","pages":"512-6"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02470987","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12975378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Mechanical properties and immunogenicity of vascular xenografts. 异种血管移植物的力学特性和免疫原性。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470991

Y Murayama, S Sato, T Oka

引用次数: 3

The possible involvement of platelet activation in endotoxin-induced renal insufficiency in a rabbit model. 兔内毒素致肾功能不全模型中血小板活化的可能参与。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470992

M Yokota, J Kambayashi, M Sakon, H Tahara, E Shiba, T Kawasaki, T Mori

{"title":"The possible involvement of platelet activation in endotoxin-induced renal insufficiency in a rabbit model.","authors":"M Yokota, J Kambayashi, M Sakon, H Tahara, E Shiba, T Kawasaki, T Mori","doi":"10.1007/BF02470992","DOIUrl":"https://doi.org/10.1007/BF02470992","url":null,"abstract":"The effects of the anticoagulants, heparin and low molecular weight heparin (LMWH), and the antiplatelet agents, prostaglandin E1 (PGE1) and aspirin, on endotoxin-induced renal insufficiency not induced by prerenal factors, were investigated using rabbits to evaluate the clinical usefulness of these drugs and their possible involvement in the activation of hemostasis in renal insufficiency. The intravenous administration of PEG1, at 0.4 microgram/kg/min, or aspirin, at 5 mg/kg, significantly restored all the parameters of renal function measured in the present study, namely, effective renal plasma flow, glomerular filtration rate and urine N-acetyl-beta-D-glucosaminidase, as well as histological renal ischemic changes. On the other hand, neither heparin nor LMWH, even at a high dose, improved any parameter. As the antiplatelet effect is the common property of PGE1 and aspirin, it is suggested that the activation of platelets may be prerequisite to the occurrence of renal insufficiency induced by endotoxin. The results of this study thus show that PGE1 or aspirin may be applied in clinical use for renal insufficiency complicated by sepsis or endotoxemia.","PeriodicalId":22610,"journal":{"name":"The Japanese journal of surgery","volume":"21 5","pages":"542-6"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02470992","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12833065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The prognostic value of tumor-associated carbohydrate structures correlated with gene amplifications in human breast carcinomas. 肿瘤相关碳水化合物结构与人类乳腺癌基因扩增相关的预后价值

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470985

T Fukutomi, S Hirohashi, H Tsuda, T Nanasawa, H Yamamoto, M Itabashi, Y Shimosato

{"title":"The prognostic value of tumor-associated carbohydrate structures correlated with gene amplifications in human breast carcinomas.","authors":"T Fukutomi, S Hirohashi, H Tsuda, T Nanasawa, H Yamamoto, M Itabashi, Y Shimosato","doi":"10.1007/BF02470985","DOIUrl":"https://doi.org/10.1007/BF02470985","url":null,"abstract":"The effects of cell surface sugar chains combined with certain gene amplifications of breast cancers on the prognosis of patients were studied and the relationships between the sugar chains of cancer cells and amplifications of the proto-oncogenes c-myc, int-2 and c-erb B-2, evaluated. One hundred and fifty three human breast carcinoma tissues were investigated by an immunohistochemical technique using the avidinbiotin-peroxidase method with 1 lectin (HPA; Helix Pomatia) and 4 monoclonal antibodies (B-72-3, St-439, anti-Tn and anti-T). The positive rates of HPA, St-439, B-72-3, anti-Tn and anti-T were 43 per cent (63/153), 52 per cent (80/153), 53 per cent (81/153), 64 per cent (98/153) and 89 per cent (136/153), respectively. Patients whose cancers had positive HPA staining were found to have a lower survival rate than those with negative HPA staining (p less than 0.05), whereas those whose cancers had positive St-439 staining showed a better prognosis than those with negative St-439 staining (p less than 0.01). The positive rate of HPA was related to the gene amplification of c-myc proto-oncogene (p less than 0.01), whereas the negative rate of St-439 was correlated with the gene amplification of c-erb B-2 (p less than 0.01). These data indicate the prognostic value of HPA and St-439 and also the relationships between the gene amplifications and carbohydrate structures in breast cancer cells.","PeriodicalId":22610,"journal":{"name":"The Japanese journal of surgery","volume":"21 5","pages":"499-507"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02470985","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12851860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Surgical experience with nonparasitic cysts of the liver--the characteristics and constituents of cyst fluid. 肝脏非寄生囊肿的手术经验——囊肿液的特征和成分。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470989

T Nagao, S Inoue, M Izu, Y Wada, N Kawano, Y Morioka

{"title":"Surgical experience with nonparasitic cysts of the liver--the characteristics and constituents of cyst fluid.","authors":"T Nagao, S Inoue, M Izu, Y Wada, N Kawano, Y Morioka","doi":"10.1007/BF02470989","DOIUrl":"https://doi.org/10.1007/BF02470989","url":null,"abstract":"Fifteen patients with nonparasitic hepatic cysts underwent surgery to relieve abdominal complaints, at the First Surgical Department, Tokyo University Hospital between 1966 and 1989. Total removal of the cyst was carried out in 14 of the patients, while puncture and aspiration only were performed in the other patient in whom a cyst had ruptured spontaneously, after which hemoperitoneum was observed at emergency laparotomy. The size of the cysts varied from 7-19 cm with a mean of 12.4 cm. Histological study revealed a congenital cyst in 14 patients and a cystadenoma in one. The epithelium lining of the internal surface of the congenital cysts was highly atrophic and desolated and often disappeared. Examination of the cyst fluid revealed the same concentration of electrolytes as in the serum. Hepatic enzyme levels were usually lower than in the serum, but lactic dehydrogenase and aminotransferase levels were elevated in a few cases. Tumor marker levels of the cyst fluid were higher than those in the serum in four of five patients examined.","PeriodicalId":22610,"journal":{"name":"The Japanese journal of surgery","volume":"21 5","pages":"521-7"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02470989","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12975380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A detailed histological study on occult metastasis of the lymph nodes. 淋巴结隐匿性转移的详细组织学研究。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470990

S Natsugoe, T Aiko, H Shimazu

{"title":"A detailed histological study on occult metastasis of the lymph nodes.","authors":"S Natsugoe, T Aiko, H Shimazu","doi":"10.1007/BF02470990","DOIUrl":"https://doi.org/10.1007/BF02470990","url":null,"abstract":"One representative microsection from each lymph node was carefully surveyed for metastasis in a routine examination. To scrutinize the existence of occult metastasis, three additional sections were then made from half of the remaining lymph node. A total of 1,698 lymph nodes taken from 55 patients with carcinoma of the esophagus, stomach, colon, thyroid or breast were thus reexamined histologically. The initial examination was not able to prove any metastasis in these lymph nodes. Upon reexamination, however, involvement by cancer cells was detected in 10 nodes of 7 patients. The maximum diameter of the metastatic foci varied from 0.2 mm to 1.3 mm and was less than 0.5 mm in more than half of the nodes. The metastatic patterns in the nodes were classified into three types, i.e., marginal sinus type, medullary sinus type and mixed type. The marginal sinus type was the most frequent, with the mixed type being next and the medullary sinus type being found in only one node. Accordingly, surgeons should keep the possibility of occult metastasis in mind and the marginal sinus of the lymph node should be carefully examined in order to detect any small foci of metastasis.","PeriodicalId":22610,"journal":{"name":"The Japanese journal of surgery","volume":"21 5","pages":"528-32"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02470990","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12975381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Cryopreservation of hamster pancreatic islets using a rapid cooling rate. 仓鼠胰岛快速冷冻保存的研究。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02470993

W Fukushima, M Note, Y Kojima, G Nakagawara

{"title":"Cryopreservation of hamster pancreatic islets using a rapid cooling rate.","authors":"W Fukushima, M Note, Y Kojima, G Nakagawara","doi":"10.1007/BF02470993","DOIUrl":"https://doi.org/10.1007/BF02470993","url":null,"abstract":"To clarify the possibility of developing a rapid cooling rate for islet cryopreservation, we used a cooling rate of 25 degrees C/min for hamster pancreatic islet cryopreservation using 15 per cent dimethylsulfoxide as a cryoprotectant. After preservation, these islets were examined for their morphology and function by assaying the insulin release after glucose stimulation and the contents of the insulin and DNA in 10 islets. In addition, islet cell replicatory activity was investigated by an autoradiographic technique. The effects of transplantation of the islets upon isogeneic and xenogeneic transplantation were also examined. Freezing using a rapid cooling rate of 25 degrees C/min was found to be as effective as a slow cooling rate of 1 degree C/min for hamster islet cryopreservation. Morphologically, the cryopreserved islets appeared to be similar to the non-frozen cultured islets. The glucose-stimulated insulin release and cell replicatory activities in vitro also remained unchanged, whereas the number of cells per islet decreased slightly after cryopreservation. The grafting of cryopreserved islets normalized streptozotocin induced hyperglycemia following isogeneic transplantation. On the other hand, no prolongation of graft survivals in the case of the xenogeneic transplantation of hamster islets to rats was observed. The isogeneically transplanted islets exhibited the same cell replicatory activities in vivo, which was even higher compared that of normal hamster pancreatic islets in situ. In conclusion, the present findings indicate that hamster pancreatic islets can be successfully cryopreserved using a rapid cooling rate, however, it does not appear that this treatment reduces islet vulnerability to xenogeneic graft rejection.","PeriodicalId":22610,"journal":{"name":"The Japanese journal of surgery","volume":"21 5","pages":"547-55"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02470993","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12975383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

mRNA expression of topoisomerase II in human tumors and normal tissues. 拓扑异构酶II在人肿瘤和正常组织中的mRNA表达。

The Japanese journal of surgery Pub Date : 1991-09-01 DOI: 10.1007/BF02471001

R Kim, N Hirabayashi, M Nishiyama, T Yorishima, T Toge, K Okada

引用次数: 3