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The Johns Hopkins medical journal最新文献

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Antagonism of acute copper(II)-induced renal lesions by sodium 2,3-dimercaptopropanesulfonate. 2,3-二巯基丙磺酸钠拮抗急性铜(II)诱导的肾损害。
The Johns Hopkins medical journal Pub Date : 1982-12-01
W M Mitchell, M A Basinger, M M Jones
{"title":"Antagonism of acute copper(II)-induced renal lesions by sodium 2,3-dimercaptopropanesulfonate.","authors":"W M Mitchell,&nbsp;M A Basinger,&nbsp;M M Jones","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acute copper(II) sulfate poisoning in the mouse induces renal tubular degeneration and necrosis. Timely administration of sodium 2,3-dimercaptopropane-sulfonate (DMPS) effectively prevented the development of the morphological renal sequelae of copper intoxication. During the time course of this study (5 days), no copper-induced hepatic lesions were observed. DMPS and its preformed copper complex possess low inherent toxicity with no hepatorenal lesions occurring over a 5-day period. These findings suggest that DMPS may be an effective antidote in acute and chronic copper poisoning in humans.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"283-5"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Juvenile rheumatoid arthritis. 幼年类风湿性关节炎。
The Johns Hopkins medical journal Pub Date : 1982-12-01
F C Arnett, L E Widman, R S Feinstein
{"title":"Juvenile rheumatoid arthritis.","authors":"F C Arnett,&nbsp;L E Widman,&nbsp;R S Feinstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"313-7"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18031923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
This is the final issue of The Johns Hopkins Medical Journal. 这是约翰·霍普金斯医学杂志的最后一期。
The Johns Hopkins medical journal Pub Date : 1982-12-01
S Boyer
{"title":"This is the final issue of The Johns Hopkins Medical Journal.","authors":"S Boyer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"263-82"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17811003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fetal mortality associated with cleft lip and cleft palate. 唇腭裂与胎儿死亡率的关系。
The Johns Hopkins medical journal Pub Date : 1982-12-01
K R Dronamraju, D Bixler, P P Majumder
{"title":"Fetal mortality associated with cleft lip and cleft palate.","authors":"K R Dronamraju,&nbsp;D Bixler,&nbsp;P P Majumder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Analysis of 1,516 pregnancies in sibships of probands with cleft lip with or without cleft palate [CL(P)], and 774 pregnancies in those of probands with isolated cleft palate (CP) indicated that fetal mortality significantly increases with liability to clefting. These data are compatible with the multifactorial two-threshold model, according to which a lower threshold level of liability results in a cleft formation whereas a higher level of liability causes a fetal death.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"287-9"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Rieger syndrome: a heritable disorder associated with glaucoma. 里格尔综合征:一种与青光眼相关的遗传性疾病。
The Johns Hopkins medical journal Pub Date : 1982-12-01
J R Heckenlively, S J Isenberg, L E Fox
{"title":"The Rieger syndrome: a heritable disorder associated with glaucoma.","authors":"J R Heckenlively,&nbsp;S J Isenberg,&nbsp;L E Fox","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"351-5"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18192581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Torsion dystonia. 扭转肌张力障碍。
The Johns Hopkins medical journal Pub Date : 1982-12-01
R C Wachtel, M L Batshaw, R Eldridge, W Jankel, M Cataldo
{"title":"Torsion dystonia.","authors":"R C Wachtel,&nbsp;M L Batshaw,&nbsp;R Eldridge,&nbsp;W Jankel,&nbsp;M Cataldo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"355-61"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18192582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social ramifications of control of microbial disease. 微生物疾病控制的社会后果。
The Johns Hopkins medical journal Pub Date : 1982-12-01
W McDermott, D E Rogers
{"title":"Social ramifications of control of microbial disease.","authors":"W McDermott,&nbsp;D E Rogers","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"302-12"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17811004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebro-hepato-renal (Zellweger) syndrome and neonatal adrenoleukodystrophy: similarities in phenotype and accumulation of very long chain fatty acids. 脑-肝-肾(齐薇格)综合征和新生儿肾上腺白质营养不良:表型和长链脂肪酸积累的相似性。
The Johns Hopkins medical journal Pub Date : 1982-12-01
F R Brown, A J McAdams, J W Cummins, R Konkol, I Singh, A B Moser, H W Moser
{"title":"Cerebro-hepato-renal (Zellweger) syndrome and neonatal adrenoleukodystrophy: similarities in phenotype and accumulation of very long chain fatty acids.","authors":"F R Brown,&nbsp;A J McAdams,&nbsp;J W Cummins,&nbsp;R Konkol,&nbsp;I Singh,&nbsp;A B Moser,&nbsp;H W Moser","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"344-51"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18192580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatitis prophylaxis. 肝炎预防。
The Johns Hopkins medical journal Pub Date : 1982-12-01
R D Aach
{"title":"Hepatitis prophylaxis.","authors":"R D Aach","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"318-25"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17249304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presence of fungiform papillae in classic dysautonomia. 典型自主神经异常中真菌状乳头的存在。
The Johns Hopkins medical journal Pub Date : 1982-12-01
N Gadoth, D Margalith, N Schlien, E Svetliza, A Litwin
{"title":"Presence of fungiform papillae in classic dysautonomia.","authors":"N Gadoth,&nbsp;D Margalith,&nbsp;N Schlien,&nbsp;E Svetliza,&nbsp;A Litwin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lack of fungiform papillae over the surface of the tongue is considered essential for the diagnosis of familial dysautonomia. We describe two cases with dysautonomia in which the diagnosis was delayed because numerous fungiform papillae were easily seen. Only a close inspection of the tongue with an ophthalmologic slit lamp revealed that each papilla was degenerated and atrophic. Lacking a clinical sine qua non or easily available diagnostic laboratory tests, fungiform papillae should be studied in detail to establish not only that their number is sufficient but also that their shape and structure are normal. The simple technique described enables confirmation of the diagnosis in children and newborns in whom familial dysautonomia is suspected.</p>","PeriodicalId":22609,"journal":{"name":"The Johns Hopkins medical journal","volume":"151 6","pages":"298-301"},"PeriodicalIF":0.0,"publicationDate":"1982-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18192577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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