The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy最新文献_第10页

Relationship Between Psychological Distress and Irritable Bowel Syndrome (IBS) in Medical Students of Pelita Harapan University 希望大学医学生心理困扰与肠易激综合征的关系

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020199-206

S. Nanda, V. Sungono

{"title":"Relationship Between Psychological Distress and Irritable Bowel Syndrome (IBS) in Medical Students of Pelita Harapan University","authors":"S. Nanda, V. Sungono","doi":"10.24871/2132020199-206","DOIUrl":"https://doi.org/10.24871/2132020199-206","url":null,"abstract":"Background: Irritable bowel syndrome is a functional disorder with recurrent abdominal discomfort associated with abnormalities in gut motility. One of the risk factors for IBS is anxiety and depression. This study aims to find out the relationship between medical student’s psychosocial conditions, measured by depression and anxiety with incidence of IBS. Gastrointestinal-specific anxiety (GSA), a subset of general anxiety, is measured and its relationship with incidence of IBS is also evaluated.Method: This research is a cross sectional study. Sample consists of 168 medical students from UPH batch 2016-2018 that fits into inclusion and exclusion criteria. Data is collected with demographics questionnaire, Rome IV IBS Criteria, Depression, Anxiety and Stress Scale 21, and Visceral Sensitivity Index. Categorical data between depression and anxiety and IBS is analyzed with Chi Square. GSA is a numerical data and its relationship with IBS is analyzed with t-test. Because GSA All statistical data is analyzed using SPSS version 22.0.Results: Results showed that from 168 samples that are acquired for this research, 65 (38,7%) are IBS and 103 (61,3%) are non-IBS. Significant associations are found between depression (p=0,03), anxiety (p=0,039), gastrointestinal-specific anxiety (p0,001), and obesity (p=0,026) with incidence of IBS.Conclusion: There is a significant association between depression and anxiety with incidence of IBS.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75974118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evaluation of GeneXpert for Quantification Viral Load Hepatitis C Virus GeneXpert用于丙型肝炎病毒载量定量的评价

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020182-187

C. Jasirwan, I. Hasan, A. Sulaiman, R. Gani

{"title":"Evaluation of GeneXpert for Quantification Viral Load Hepatitis C Virus","authors":"C. Jasirwan, I. Hasan, A. Sulaiman, R. Gani","doi":"10.24871/2132020182-187","DOIUrl":"https://doi.org/10.24871/2132020182-187","url":null,"abstract":"Background: GeneXpert has been used for Mycobacterium tuberculosis testing, but is currently available for HCV RNA testing. GeneXpert assay is expected to be more accurate, efficient, and cost-effective for HCV viral load quantification. This study intended to evaluate the new method quantification of plasma HCV RNA by the GeneXpert in comparison to the Roche Cobas TaqMan 96 as standard diagnostic tools.Method: A total of 54 HCV-infected plasma samples with anti-HCV positive were examined by GeneXpert assay, followed with Cobas TaqMan 96 for quantification of HCV RNA. Correlation was performed by Pearson test (in log10) and diagnostic test by Chi-square test. Sensitivity and specificity of the GeneXpert assay measured by calculating 2x2 contingency table. Bland-Altman plot were generated to assess the mean difference between the two assays.Results: GeneXpert has strong correlation to the Roche Cobas TaqMan 96 (R=0.993; P value 0.001). GeneXpert has sensitivity of 100% (95% CI: 90–100%) and specificity of 90% (95% CI: 54.1–99.5%). The Bland Altmand plot showed that one sampel has 1 log difference with the Roche Cobas TaqMan 96 measurement result.Conclusion: There was a strong correlation in the measurement of HCV RNA by GeneXpert and moreover its assay also has an excellent overall performance compared to Cobas TaqMan 96. Thus, it can be considered as a reliable tools for HCV virological response monitoring.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83233317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Risk Factors for Gastrointestinal Symptoms post Enteral Nutrition Initiation via a Gastrostomy Tube 经胃造瘘管开始肠内营养后胃肠道症状的危险因素

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020207-211

Y. Kajihara

{"title":"Risk Factors for Gastrointestinal Symptoms post Enteral Nutrition Initiation via a Gastrostomy Tube","authors":"Y. Kajihara","doi":"10.24871/2132020207-211","DOIUrl":"https://doi.org/10.24871/2132020207-211","url":null,"abstract":"Background: Percutaneous endoscopic gastrostomy (PEG) facilitates long-term enteral nutrition. However, parenteral nutrition prior to PEG tube placement can cause impaired gastrointestinal function. Additionally, upon initiation of enteral feeding via a PEG tube, some patients suffer from gastrointestinal symptoms (e.g., vomiting, diarrhea), which reduce their quality of life and increase the nursing workload. Method: This retrospective study included 155 patients upon whom the author performed PEG as the attending physician. Enteral nutrition was started through the PEG tube on the third day after its placement. The following characteristics were analyzed: age, gender, indications for PEG, preoperative enteral nutrition, administered liquid nutrients, daily dosage of nutrients, serum albumin levels, serum alanine aminotransferase levels, serum creatinine levels, serum hemoglobin levels, and vomiting or diarrhea within seven days after the initiation of PEG feeding. A logistic regression model was used to identify the risk factors contributing to gastrointestinal symptoms, and three variables were sequentially introduced into the model—preoperative non-enteral nutrition, hypoalbuminemia, and administration of non-elemental diets. Results: Vomiting and diarrhea occurred in 10 and 15 patients, respectively. There were significant differences in administered nutrients and serum albumin levels between patients with and without gastrointestinal symptoms. Multivariate analysis revealed that the adjusted odds ratios for administration of non-elemental diets and serum albumin level ≤3.2 g/dL were 8.05 (95% confidence interval (CI): 2.66–24.4; p < 0.001) and 3.81 (95% CI: 1.33–10.9; p < 0.05), respectively. Conclusion: The administration of non-elemental diets and a serum albumin level ≤3.2 g/dL were significant risk factors.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"21 1","pages":"207-211"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41666856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Bowel Obstruction and Perforation as Emergency Presenting Sign of Colorectal Cancer with Peritoneal Carcinomatosis: A Case Report and Review 结直肠癌合并腹膜癌的急症表现为肠梗阻及穿孔1例报告及回顾

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020235-240

R. Adiwinata, Linda Rotty, M. Tendean, B. J. Waleleng, Fandy Gosal, Luciana Rotty, Jeanne Winarta, Andrew Waleleng

引用次数: 0

The Role of GERD Questionnaire (GERD-Q) for Reflux Esophagitis 反流性食管炎胃反流问卷(GERD- q)的作用

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020169-170

Kaka Renaldi

引用次数: 0

Constipation in Elderly Population and Its Appropriate Management 老年人便秘及其适当管理

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020212-219

A. Kurniawan, Ulfa Kholili, Novira Widajanti

{"title":"Constipation in Elderly Population and Its Appropriate Management","authors":"A. Kurniawan, Ulfa Kholili, Novira Widajanti","doi":"10.24871/2132020212-219","DOIUrl":"https://doi.org/10.24871/2132020212-219","url":null,"abstract":"Constipation is a gastrointestinal disorder commonly found in the community, especially in the elderly with various comorbidities. This problem culminates with the increasing incidence along with aging, increasing therapeutic cost, and decreasing the quality of life in this population. Some of the underlying causes are the difference in the terminology of constipation, shallow understanding of its pathophysiology, and poor management. The pathophysiology, including slow transit constipation, dyssynergic defecation, and normal transit constipation, is the most critical foundation in managing constipation accordingly. Diagnostic approaches should be made by history taking, including complaints based on Rome III, lifestyle, contributing factors, past medical history, and medications. Physical examination is considered incomplete without rectal examination. Thorough history taking and comprehensive physical examination have more diagnostic value than additional physiological workup. Management of constipation consists of non-pharmacological and pharmacological approaches, such as conventional laxative or more recent agents with better efficacy. Therapeutical management should correspond to the underlying pathophysiology. Therefore it is important to be able to recognize constipation and make the right management approach in the elderly.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73420949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iron Deficiency Anemia as The Only Manifestation of Colon Cancer in Male Patient: A Case Report 缺铁性贫血是男性结肠癌的唯一表现:1例报告

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020241-243

W. Rajabto, P. T. Sakti, Andi Putra Kevinsyah

引用次数: 0

The Association between Interleukin-6 and Mean Platelet Volume Levels in Central Obesity with or without Non-Alcoholic Fatty Liver Disease 中心性肥胖伴或不伴非酒精性脂肪肝患者白细胞介素-6与血小板平均体积水平的关系

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020193-198

L. Rotty, Nelly Tendean, Nancy Lestari, R. Adiwinata

{"title":"The Association between Interleukin-6 and Mean Platelet Volume Levels in Central Obesity with or without Non-Alcoholic Fatty Liver Disease","authors":"L. Rotty, Nelly Tendean, Nancy Lestari, R. Adiwinata","doi":"10.24871/2132020193-198","DOIUrl":"https://doi.org/10.24871/2132020193-198","url":null,"abstract":"Background: Obesity had become a global problem today. Obesity is a significant risk factor of cardiovascular and other metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). It remains unclear if the increased mean platelet volume (MPV) at the steatosis state is practicable as early detection of the occurrence of fatty liver in individuals with central obesity. This study aims to determine the association of interleukin-6 (IL-6) and MPV levels in central obesity with or without NAFLD. Method: This study was descriptive-analytic with a cross-sectional approach conducted in Prof. dr. R. D. Kandou Manado general hospital from May to July 2018. Consecutive sampling was performed based on inclusion criteria, then IL-6, MPV, and abdominal ultrasound examinations were performed. Results: This study included 40 samples of men with central obesity, 28 people (70%) among them were diagnosed with NAFLD. The Fisher exact test showed an association between NAFLD and an increase in IL-6 (p = 0.039), also between MPV and NAFLD (p=0.015). Pearson correlation test showed there was no significant correlation between IL-6 and MPV in the NAFLD sample group (p = 0.084; r -0.332) and in the non-NAFLD sample group (p = 0.564; r -0.186). Conclusion : Elevated MPV and IL-6 values may be used as marker for NAFLD presence among central obesity patients.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"21 1","pages":"193-198"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48404707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020220-225

A. Sulaiman, Juferdy Kurniawan, C. Jasirwan, Saut Nababan, Kemal F Calista, C. Lesmana, I. Hasan, R. Gani, B. K. D. Mandasari

{"title":"COVID-19 Related to Liver Impairment and Its Impact on Chronic Liver Disease","authors":"A. Sulaiman, Juferdy Kurniawan, C. Jasirwan, Saut Nababan, Kemal F Calista, C. Lesmana, I. Hasan, R. Gani, B. K. D. Mandasari","doi":"10.24871/2132020220-225","DOIUrl":"https://doi.org/10.24871/2132020220-225","url":null,"abstract":"By late December 2019, a novel beta-coronavirus, named as COVID-19 (2019-nCoV), was discovered in Wuhan, Hubei Province, China which epidemiologically linked to a Huanan seafood market in Wuhan. Coronavirus Disease 2019 or COVID-19 cases are growing rapidly from Wuhan to many countries, finding the health care system unprepared to face this threat. No effective drugs are clinically approved to manage the disease and strategies to protect the most vulnerable from developing severe illness and infection is still unclear. Information on how COVID-19 virus infection may affects many organs, especially the liver and the relevance of pre-existing liver disease in patients as a risk factor for the infection or disease severity are still scarce and inconclusive. Besides, the recommendation and consideration in liver transplant patients, hepatocellular carcinoma, or patient on immunosuppressive therapy still need further analysis Therefore, the information on the mechanism and treatment of COVID-19 related liver injury in patients with or without pre-existing liver disease should be considered.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88930037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Characteristics of Non-Alcoholic Fatty Liver Disease Patients at Dr. M. Djamil General Hospital Padang 巴东Djamil总医院非酒精性脂肪肝患者的特点

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Pub Date : 2020-12-30 DOI: 10.24871/2132020171-176

Husna Yetti, Nada Utami Prahastiwi, R. Susanti, E. Decroli, Saptino Miro

{"title":"Characteristics of Non-Alcoholic Fatty Liver Disease Patients at Dr. M. Djamil General Hospital Padang","authors":"Husna Yetti, Nada Utami Prahastiwi, R. Susanti, E. Decroli, Saptino Miro","doi":"10.24871/2132020171-176","DOIUrl":"https://doi.org/10.24871/2132020171-176","url":null,"abstract":"Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is emerging as chronic liver disease, both in developed and developing countries. NAFLD affects up to 25% population worldwide. The incidence of NAFLD associated with various risk factors supporting the development of the fatty liver. This study aim is to know the characteristics of NAFLD patients. Method: Retrospective study was conducted from medical records to find the characteristics of patients diagnosed with NAFLD at Dr. M. Djamil General Hospital from January 2016 – December 2018. Results: Seventy-seven patients were diagnosed with NAFLD. The majority of NAFLD patients were male and female at 36-45 years old and female at > 65 years old. Unemployed females were more prevalent compared to males. Dyslipidemia was the most component of a metabolic syndrome found in NAFLD patients. From laboratory findings, 55.56% of patients have increased aspartate aminotransferase (AST) levels, while 52.78% have increased alanine aminotransferase (ALT) levels. Ultrasonography used widely as a diagnostic device to detect NAFLD. Pharmacological therapy based on American Asociation for the Study of Liver Disease (AASLD) recommendation that used widely to treat patients with NAFLD was statin. Conclusion: The incidence of NAFLD was found to vary in different age ranges and sexes. Dyslipidemia occurred in most of NAFLD patients. AST and ALT levels increased in about half of the patients. Abdomen ultrasound as a diagnostic modality that was widely used.","PeriodicalId":22564,"journal":{"name":"The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy","volume":"21 1","pages":"171-176"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43543278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0