The Internet Journal of Oncology最新文献

Internal Mammary Node Evaluation And Elective Nodal Treatment In Medial Breast Cancers: A Case Report And Review Of The Literature. 内侧乳腺癌乳腺内淋巴结评估及选择性淋巴结治疗:1例报告及文献复习。

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2adc

E. Miles, C. Cinnamond, C. Allgeier, J. Nelson

{"title":"Internal Mammary Node Evaluation And Elective Nodal Treatment In Medial Breast Cancers: A Case Report And Review Of The Literature.","authors":"E. Miles, C. Cinnamond, C. Allgeier, J. Nelson","doi":"10.5580/2adc","DOIUrl":"https://doi.org/10.5580/2adc","url":null,"abstract":"The evaluation and treatment of the internal mammary nodes (IMNs) in patients with axillary node positive breast cancer undergoing breast conservation therapy is somewhat controversial. A recently reported randomized trial of radiation therapy to the local regional nodes (including the IMNs) in patients undergoing breast conservation therapy demonstrated an improvement in disease free survival and overall survival with this additional nodal irradiation. For patients with tumors in the medial quadrants of the breast, consideration of peritumoral sentinel lymph node procedures with or without periareolar injections should be considered as demonstrated lymphatic drainage to the IMNs may indicate a greater need to consider their inclusion in adjuvant radiation therapy fields, regardless of clinical or radiographic involvement. These nodes may be treated either with a separate IMN field or partially-wide tangents. The benefits of this inclusion must be weighed against the risks of side effects of increased radiation exposure of lung, heart and contralateral breast tissue. Additional long-term data from randomized trials currently underway and maturing may help to define the risks versus the benefits of IMN elective nodal irradiation","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78687774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adenocarcinoma Of The Rete Testis With Secondaries In The Skin – Review Of Literature And Case Report 伴有皮肤继发的睾丸网腺癌——文献回顾及病例报告

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2a8c

Ashwin Pai, H. S. Ram, T. Sarkar, S. Bhat, Ashfaque Mohammed

引用次数: 0

A Rare Case Of Dysgerminoma In A 58-Year Old Postmenopausal Woman In Makurdi, North Central Nigeria. 尼日利亚中北部马库尔迪一名58岁绝经后妇女罕见的无生殖细胞瘤病例。

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2a8b

Hembah-Hilekaan Sk, M. Tp

{"title":"A Rare Case Of Dysgerminoma In A 58-Year Old Postmenopausal Woman In Makurdi, North Central Nigeria.","authors":"Hembah-Hilekaan Sk, M. Tp","doi":"10.5580/2a8b","DOIUrl":"https://doi.org/10.5580/2a8b","url":null,"abstract":"The cause of ovarian cancers is not known but the most common risk factor is a positive family history of ovarian or breast cancer. Primary tumors of the ovaries may arise from the epithelium (82%), sex cord and germ cell (20%) areas. About 3-5% of all germ cell tumors (GCTs) are malignant with the most common being the dysgerminoma which also accounts for 4-5% of all ovarian cancers. Dysgerminomas are most commonly seen in women of reproductive age who are sexually active and they make up to 60% of all malignant ovarian tumors in women younger than 20 years. We present a rare case of ovarian dysgerminoma in a 58-year old post menopausal woman who, presented to the gynecological unit of a secondary health care center in Makurdi, Nigeria. She had staging laparotomy and cytoreductive surgery. Initial chemotherapy with bleomycin, etoposide and cisplatin showed a good response. The appearance of this cancer in this age group should be a reminder to practitioners of the need to develop effective screening methods for ovarian cancers and the sensitization of patients to present early while attempts are made to open up well equipped cancer treatment centers, with adequately trained personnel. This is important since, ovarian cancers are the second most common gynecological malignancies and have the highest case fatality world wide; but once diagnosed dysgerminomas respond well to treatment.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85092472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Adjuvant Radiation Therapy For Wedge-Resected Non-Small Cell Lung Cancer Adjacent To A Large Thoracic Aortic Aneurysm: A Case Report And Review Of The Literature 楔形切除非小细胞肺癌伴大胸主动脉瘤的辅助放射治疗:1例报告及文献复习

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2a8a

C. E. Miles, C. Strange

{"title":"Adjuvant Radiation Therapy For Wedge-Resected Non-Small Cell Lung Cancer Adjacent To A Large Thoracic Aortic Aneurysm: A Case Report And Review Of The Literature","authors":"C. E. Miles, C. Strange","doi":"10.5580/2a8a","DOIUrl":"https://doi.org/10.5580/2a8a","url":null,"abstract":"Lung cancer is the leading cause of cancer death in the United States, with an estimated 222,500 new cases diagnosed in 2010; non-small cell lung cancer (NSCLC) accounted for approximately 85% of these malignancies. Treatment for early stage NSCLC in an operable patient involves lobar resection. Thoracic aortic aneurysms form as a result of exposure to smoking, hypertension, atherosclerosis, and genetic connective tissue disorders. The literature is silent on the optimum course of action when the anatomic lobar resection for NSCLC is limited by a thoracic aortic aneurysm, particularly when a close surgical margin indicates consideration of adjuvant radiation therapy. Although there is some literature documenting the radiation injury pattern to intact great blood vessels, the literature is silent on the potential for further injury to the wall of the great vessels in the presence of an existing aneurysm. With the increase in the use of definitive stereotactic body radiotherapy for early stage NSCLC in medically inoperable patients, there is a potential for an increased risk of vascular injury secondary to radiation in patients whose vessels already have baseline atherosclerotic damage. Herein, we report a case of a patient diagnosed with wedge-resected early stage NSCLC with close margin in the immediate vicinity of a pre-existing large thoracic aortic aneurysm.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80325204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Pancreatitis Following VAD Chemotherapy Combination Consisting Of Vincristine, Doxorubicin, And Dexamethasone In A Newly Diagnosed Multiple Myeloma Patient: A Case Report. VAD联合长春新碱、阿霉素和地塞米松化疗后急性胰腺炎一例新诊断的多发性骨髓瘤患者

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2b68

S. Toprak, S. Ocal, B. Erismis, E. Yıldırım, R. Altun, S. Karakuş, I. Tek, P. Topçuoğlu

引用次数: 3

A Rare Case Of Colon Cancer With Metastases To The Bone With Review Of The Literature 罕见结肠癌骨转移1例并文献复习

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2c4e

J. Rodrigues, A. Ramani, N. Mitta, P. Joshi

引用次数: 6

Rhabdomyosarcoma with Bone Marrow Infiltration: A Diagnostic Dilemma 横纹肌肉瘤伴骨髓浸润:诊断困境

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2a8d

R. Khanna, D. Nayak, C. Manohar, N. Suvarna, S. Belurkar, S. Ray, P. Srilatha

{"title":"Rhabdomyosarcoma with Bone Marrow Infiltration: A Diagnostic Dilemma","authors":"R. Khanna, D. Nayak, C. Manohar, N. Suvarna, S. Belurkar, S. Ray, P. Srilatha","doi":"10.5580/2a8d","DOIUrl":"https://doi.org/10.5580/2a8d","url":null,"abstract":"Rhabdomyosarcoma is the most common soft tissue sarcoma in children and adolescents. In adults, the prevalence is much lower. Most patients present with a mass in the head and neck region, urogenital region or even with distal extremity involvement. A bone marrow infiltration at the time of clinical presentation has also been documented in literature. But a simultaneous marrow infiltration can simulate a hematopoietic neoplasm, leading to diagnostic errors. We document one such challenging case of a 47 year old male patient presenting with bicytopenia. Patient was hospitalized following a referral due to a mass in the left cheek, diagnosed earlier as clear cell sarcoma. Bone marrow aspirates yielded a dry tap, with sinusoidal blood and both the aspirate as well as the imprint smear showed pleomorphic cells with vacuolated cytoplasm. The corresponding trephine biopsy showed diffuse and interstitial infiltrates of rhabdoid cells with focal areas of infarct. Considering the morphological details, a diagnosis of rhabdomyosarcoma was rendered after ruling out other possibilities. A review of the lesional biopsy with ancillary techniques eventually corroborated the bone marrow diagnosis.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86592814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Dermatofibrosarcoma Protuberans: A Deceptive Neoplasm. 隆突性皮肤纤维肉瘤:一种具有欺骗性的肿瘤。

The Internet Journal of Oncology Pub Date : 2012-01-24 DOI: 10.5580/2b53

K. Vagholkar, Indumati Gopinathan, Shalini Nair, Siddartha Nachane, O. Joglekar, Amogh Vaishampayan

引用次数: 1

Prostatic Leiomyosarcoma –A Rare Case Report With Review Of Literature 前列腺平滑肌肉瘤1例并文献复习

The Internet Journal of Oncology Pub Date : 2010-12-31 DOI: 10.5580/195d

A. Dubey, G. Sivananthan, T. Bradel, R. Koul

引用次数: 6

Undiagnosed Cervical Cancer After Total Abdominal Hysterectomy In North Central Nigeria-Case Report 尼日利亚中北部全腹子宫切除术后未确诊的宫颈癌病例报告

The Internet Journal of Oncology Pub Date : 2010-12-31 DOI: 10.5580/1eff

S. Hembah-Hilekaan, J. Kigbu

{"title":"Undiagnosed Cervical Cancer After Total Abdominal Hysterectomy In North Central Nigeria-Case Report","authors":"S. Hembah-Hilekaan, J. Kigbu","doi":"10.5580/1eff","DOIUrl":"https://doi.org/10.5580/1eff","url":null,"abstract":"Back ground: Total abdominal hysterectomy (TAH) is a commonly performed surgical procedure by many doctors in the developing world, for reasons ranging from mild benign to severe malignant conditions. This is because they are often confronted with cases where treatment has to be offered to their patients either due to lack of facilities and / or personnel for appropriate diagnosis or pressure and anxiety from clients and relatives, resulting in cases of undiagnosed cervical malignancy. Many of which could have been treated differently if properly diagnosed.Objective: This study was to evaluate the uterine specimen obtained after TAH and bilateral salpingo-oopherectomy (BSO) for undiagnosed cervical bleeding for unexpected histology.Design/ methods: This was a retrospective study design. The case of a 58-year old woman with post coital bleeding who was anxious to have hysterectomy for fear of cervical cancer was analyzed after surgery with the histology report of the surgical (TAH/BSO) specimen .Result: She had TAH/BSO with excision of a cuff of the vagina. The histology of the specimen showed evidence of early locally invasive cancer of the cervix. The surgical margins were microscopically disease free. She was referred for radiotherapy at a regional centre in Nigeria (Ibadan) where she had teletherapy and two years of outpatient followup showed no recurrence or complications.Conclusion: Cases of invasive cervical cancer usually present late in this part of the world with surgical treatment not considered an option. We present a case of undiagnosed early cervical cancer in a postmenopausal woman who had successful TAH/BSO and postoperative radiotherapy. Preventive screening measures coupled with accurate diagnosis, and the improvement in manpower and facilities have been known to give better results. This is a reminder to all doctors and gynecologists of the need for cervical screening, in our hospitals.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89957774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0