A Rare Case Of Colon Cancer With Metastases To The Bone With Review Of The Literature

Abstract

Distant metastases from colon cancer spread most frequently to the liver and the lung. Risk factors include positive lymph nodes and high grade tumors.Colorectal cancer is the 3 leading cause of cancer related death in the world. Death is usually associated with recurrence and metastasis. Skeletal metastasis in primary colorectal carcinoma is an uncommon event. When such an event occurs it is usually a late manifestation of the disease. Isolated skeletal metastasis from primary colonic carcinoma is a rare event with incidence of 1.1% of all metastases from colonic cancers . The most common presenting symptom of skull metastases is a visible, localized swelling of skull produced by growing tumor that erodes outer table. Metastasis to bone gives rise to osteolysis or mixed osteolysis – osteoblastic appearance on radiography.