{"title":"About The Interconnection Between Erythropoietin, Mononuclears And Colon Carcinoma Cells","authors":"H. Bessler, M. Herman-Edelstein, M. Djaldetti","doi":"10.15226/2639-7986/3/3/00126","DOIUrl":"https://doi.org/10.15226/2639-7986/3/3/00126","url":null,"abstract":"Since centuries, medical practice has advanced concomitantly with newer therapeutic and research discoveries which improved markedly physicians’ options for treating patients and to prolong human life. In that sense the short length of time from the assumption that there is a substance responsible for regulation of erythropoiesis and creation of human recombinant erythropoietin was amazing. During the seventies, one of the authors (MD) had the “privilege” to study various effects of human urinary erythropoietin which at those times was quite Abstract","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132062980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Nickel and Hexavalent Chromium on the Haematology of the Common carp,Cyprinus carpio","authors":"A. Thatheyus","doi":"10.15226/ijhbd/3/2/00123","DOIUrl":"https://doi.org/10.15226/ijhbd/3/2/00123","url":null,"abstract":"In mammalian toxicology, clinical methods are well estab¬lished to evaluate the physiological effects of toxicants. The use of such methods is based upon a good knowledge of normal clinical values and of the relationship between physiological and biochemical alterations, and important whole animal responses. Similar knowledge has not been gained yet in fish toxicology and work is going on in transferring of various clinical methods from medical and veterinary science to fish physiology and toxicology [1]. Haematological procedures are used in the diagnosis of diseases and parasite attacks in fish. They are altered by both environmental and endogenous factors. Several toxicants induce disturbances in the red and white blood cell pattern in fish including heavy metals, pesticides, industrial effluents and other chemicals. In the present work, an attempt has been made to study the effect of nickel and hexavalent chromium on the red and white blood cell count of common carp after chronic exposure.","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128228615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Belousov, E. Malygon, V. Yavorskiy, E. Belousova
{"title":"Simple and practical method of Additive Modernization of Preservation Solutions that does not violate the Compliance requirements and Improved the Quality, Efficiency, Safety Transfusion of Preserved RBCs","authors":"A. Belousov, E. Malygon, V. Yavorskiy, E. Belousova","doi":"10.15226/IJHBD/3/2/00124","DOIUrl":"https://doi.org/10.15226/IJHBD/3/2/00124","url":null,"abstract":"Red blood cells (RBCs) transfusion is a critical, life-saving treatment for severe anemia caused by disease or chemotherapy, or by blood loss due to trauma or major surgery. For several decades RBCs components have been prepared as concentrates suspended in nutrient additive solution, which preserves and extends the shelf-life of the RBCs component, allowing up to 6–7 weeks of refrigerated storage [1]. Nevertheless, during storage RBCs undergo a complex and progressive accumulation of physicochemical changes, collectively referred to as the RBCs storage lesion [2, 3]. Recent clinical studies have identified RBCs transfusion as an independent risk factor for increased morbidities and mortalities in certain groups of patients, including trauma, cardiac surgery and the critically-ill (reviewed in [4 – 6]). Abstract","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134585276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Twenty Chemical Element Contents in Normal and Cancerous Thyroid","authors":"V. Zaichick, S. Zaichick","doi":"10.15226/IJHBD/3/2/00121","DOIUrl":"https://doi.org/10.15226/IJHBD/3/2/00121","url":null,"abstract":"Thyroid cancer (TC) is the most common endocrine malignancy. TC incidence has dramatically increased in the recent decades [1]. During the same period no other cancer has increased as much as TC. With the worldwide increase in the incidence of TC, it has become the fifth most common cancer in women [2-4]. In some countries, the incidence of TC has increased extremely fast, and it has been the most common cancer for the last years [5].","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114997292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Mudawi, N. Kassem, Abdulqadir Nashwan, M. Yassin
{"title":"Cutaneous manifestations of Nilotinib","authors":"D. Mudawi, N. Kassem, Abdulqadir Nashwan, M. Yassin","doi":"10.15226/ijhbd/3/1/00120","DOIUrl":"https://doi.org/10.15226/ijhbd/3/1/00120","url":null,"abstract":"Nilotinib is a highly selective second-generation Bcr-Abl tyrosine kinaseInhibitor (TKIs), which is effective in patients with Philadelphia chromosome–positive chronic myeloid leukemia (CML). Tyrosine kinase inhibitors have broadly similar types of non-hematological adverse side effects (AES), but some of the AES are specific to one drug compared to the others. In general, the TKIs are well tolerated with mostly (grade1-2) toxicities, and relatively limited grade (34) toxicities. For best management of CML patients receiving TKI therapy, early recognition and knowledge of potential toxicities are required, allowing for optimal management of the condition without interruption of the drug.","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133358221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Salmi, K. Shuaili, A. Metry, F. A. Ismaili, A. Hola, S. Hannawi
{"title":"The Epidemiology of Hemolytic Uremic Syndrome: Clinical Presentation, Laboratory Findings, Management and Outcomes","authors":"I. Salmi, K. Shuaili, A. Metry, F. A. Ismaili, A. Hola, S. Hannawi","doi":"10.15226/ijhbd/3/1/00119","DOIUrl":"https://doi.org/10.15226/ijhbd/3/1/00119","url":null,"abstract":"Introduction: Hemolytic-uremic syndrome (HUS) is a disease that has been described as a triad of hemolytic anemia, thrombocytopenia and renal impairment. There are two types of HUS, typical and atypical. HUS remains a leading cause of acute renal injury in children and is increasingly recognized as a cause of renal failure in adults. In our study we evaluated the demographic features, clinical characteristics, management and outcome of HUS in Omani population presented in the main tertiary hospital.","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132727026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ane Katiussa Siqueira Fröhlich, D. Brum, E. Dallegrave
{"title":"Profile of blood donors in relation to hepatitis C","authors":"Ane Katiussa Siqueira Fröhlich, D. Brum, E. Dallegrave","doi":"10.15226/IJHBD/3/1/00118","DOIUrl":"https://doi.org/10.15226/IJHBD/3/1/00118","url":null,"abstract":"Hepatitis C is among the main causes of chronic liver disease and can progress to conditions such as cirrhosis and hepato cellular carcinoma. Among the main risk factors for virus transmission are injecting drug use, occupational exposure, intravenous therapy and blood transfusion [1, 2]. Hepatitis C is of great importance for public health and health support services, since the infection may present asymptomatic for an extended period of time, besides the possibility of chronification, increasing the chances of transmission [3].","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133926193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lymphoma of vagina in a Nigerian Community","authors":"W. Onuigbo, B. Igbogbahaka","doi":"10.15226/ijhbd/3/1/00117","DOIUrl":"https://doi.org/10.15226/ijhbd/3/1/00117","url":null,"abstract":"Introduction The Merriam-Webster’s Collegiate Dictionary defines lymphoma as the malignant form of lymphatic tissue and dates 1873 as when it was first named [1]. Now, there are single case reports from Turkey [2], India [3], Italy [4], Portugal [5], China [6], Japan [7], and Spain [8]. Therefore, having encountered the single case, which appeared among the Igbo ethnic group [9], this report is deemed to be worthy of demonstration. It appeared as in other parts especially as to the bleeding and the posterior wall origin.","PeriodicalId":225199,"journal":{"name":"International Journal of Hematology and Blood Disorders","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133727349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}