Trends in Pediatrics最新文献

{"title":"Are Genetics Involved in the Development of Multisystem Inflammatory Syndromes in Children?","authors":"S. İpek, U. Güllü","doi":"10.4274/tp.2022.92486","DOIUrl":"https://doi.org/10.4274/tp.2022.92486","url":null,"abstract":"İpek S, Güllü UU. Are Genetics Involved in the Development of Multisystem Inflammatory Syndromes in Children?. ABSTRACT The relationship between Multisystem Inflammatory Syndrome in Children (MIS-C) and genetic predisposition is not well established. The aim of this article emphasize the presence of genetic predisposition in MIS-C by presenting two sibling cases from two separate families with a diagnosis of MIS-C. The patients applied with complaints of fever, abdominal pain, diarrhea and maculopapular rash. While the coronavirus disease-2019 (COVID-19) polymerase chain reaction test was negative in all cases, three had both IgM and IgG positivity, and the other case had only IgG positivity. Patients who did not define any other infection were diagnosed with MIS-C according to the Centers for Disease Control and Prevention criteria. The patients were discharged with full recovery. The fact that siblings share the same genetic background and the same environmental factors suggests that MIS-C syndrome occur in individuals with a genetic predisposition. Further genetic studies with a large MIS-C series are needed to determine which genotypic trait may cause the development of MIS-C in COVID-19 infection.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116656987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Knowledge and Awareness Level of the Pediatric Residents About the Diagnosis, Treatment and Follow-up of Urinary Tract Infection in Children","authors":"F. Devrim, Dorukhan Besin, Aslı Kantar Özşahin, Betül Pehlivan Zorlu, Özlem Dur, Ebru Yılmaz, N. Dinçel","doi":"10.4274/tp.2022.44127","DOIUrl":"https://doi.org/10.4274/tp.2022.44127","url":null,"abstract":"","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"257 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120951656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Thyroid Pathologies Detected During School Screening in Healthy School-Age Children","authors":"M. Gök, Reyhan Deveci Sevim, Sercan Öztürk, A. Anık","doi":"10.4274/tp.2022.53825","DOIUrl":"https://doi.org/10.4274/tp.2022.53825","url":null,"abstract":"Objective: The authors of this study took part in a screening program in schools in Aydın province (unpublished study). This study assessed the final thyroid pathologies of these children with pathology detected during ultrasonography (USG) screening obtained as part of the screening program. Methods: A handheld wireless point-of-care USG device was used to screen the thyroid gland. Children with thyroid pathology were invited to the hospital where detailed lab study and an USG was examined. The study obtained the thyroid measurements, parenchymal features, and noted the presence of nodules in the detailed USG examination. Nodules were classified according to the Thyroid Imaging Reporting & Data System (TI-RADS™) and an USG-guided fine needle aspiration (FNA) was performed according to TI-RADS. Results: A total of 1,553 cases from 21 schools between the ages of 6-17 were evaluated in the screening program. Thyroid pathology was detected in 176 (11.3%) cases. One hundred twenty of 176 patients’ families agreed to attend our centre for further examination, where pathology was confirmed in 108 (90.0%) of the 120 cases. Among the 108 thyroid USG pathologies, 52 (48.1%) patients had a nodule and thyroiditis; 28 (25.9%) patients had only a nodule; 28 (25.9%) patients had only thyroiditis. Thyroiditis was present in 74.0% (n=80) of the cases, of those cases 56.3% (n=45) had peripheral thyroiditis, 31.3% (n=25) had diffuse thyroiditis and 12.5% (n=10) had overweight-related changes. Nodules were present in 73.4% (n=80) of the cases. A total of 9 USG-guided FNA were performed, and their pathology results were as followed; 55.6% (n=5) benign cytology, 11.1% (n=1) follicular adenoma, 11.1% (n=1) atypia of indeterminate significance, 11.1% (n=1) non-diagnostic cytology and 11.1% (n=1) papillary thyroid cancer. Conclusion: This study showed that thyroiditis and nodules in the thyroid gland are common disorders in children. Thyroid nodules may also have a high malignancy potential and the chance of early diagnosis of thyroid cancers with screening is demonstrated.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121147893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Serum 25-hydroxyvitamin D Levels at the First Manifestation of Multiple Sclerosis in Children and Adolescents","authors":"M. Ayanoğlu, A. Tosun","doi":"10.4274/tp.2022.59144","DOIUrl":"https://doi.org/10.4274/tp.2022.59144","url":null,"abstract":"A. Assessment of Serum 25-hydroxyvitamin D Levels at the First Manifestation of Multiple Sclerosis in Children and Adolescents. ABSTRACT Objective: To evaluate serum 25-hydroxyvitamin D levels, demographic features, and anthropometric measurements at the first manifestation of disease in children and adolescents with multiple sclerosis (MS). Methods: This retrospective study included patients with MS and healthy children and adolescents. Children and adolescents whose clinical and radiological findings were compatible with the McDonald 2017 criteria and who had vitamin D results during the first relapse were included. Having an acute or chronic disease was an exclusion criterion for healthy controls. Taking a supplementation including vitamin D is an exclusion criterion for both the MS and control groups. Age, gender, anthropometric measurements, and serum levels of 25-hydroxyvitamin D were extracted from the database. Results: A total of 23 patients (female: 17, 73.9%) and 24 (female: 12, 50.0%) healthy children and adolescents were included. The median ages of the patient group and the control group were 16.33 (2.00), and 15.36 (2.29), respectively. There were no significant differences between the groups in terms of age, gender, weight-standard deviation score (SDS), height-SDS, and body mass index-SDS. Precisely, 87.0% of the patients had a vitamin D deficiency. The mean vitamin D values of the patients and the healthy controls were 12.76±5.52, and 18.75±5.86, respectively. Patients with MS had significantly lower levels of 25-hydroxyvitamin D than healthy controls (p<0.0001). Conclusion: The current study showed that most (87.0%) of the children and adolescents had vitamin D deficiency at the first manifestation of MS. Moreover, the levels of 25-hydroxyvitamin D levels were significantly lower in patients with MS than in the healthy controls.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125434518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Plasma Exchange for Treating Pediatric Neurological Diseases","authors":"G. Atay, Hatice Yazar, Seher Erdoğan, Hazal Ceren Tugrul, H. İşcan, B. Kutlubay","doi":"10.4274/tp.galenos.2022.83997","DOIUrl":"https://doi.org/10.4274/tp.galenos.2022.83997","url":null,"abstract":"","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115045694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lercanidipine Intoxication in A 16-Year-Old Adolescent","authors":"Volkan Bayar","doi":"10.4274/tp.galenos.2022.29484","DOIUrl":"https://doi.org/10.4274/tp.galenos.2022.29484","url":null,"abstract":"","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131143303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary Feeding Recommendations for A Healthy Future Generation","authors":"Gizem Yonar, Ayçıl Özturan Şirin","doi":"10.4274/tp.galenos.2022.08108","DOIUrl":"https://doi.org/10.4274/tp.galenos.2022.08108","url":null,"abstract":"World Health Organization data remark that 144 million children under the age of 5 are stunted by age. In Turkish society, the high weakness and stunting rates, especially among children aged 6-8 months, are an indication that complementary nutrition practices are not given enough importance in our country. Therefore, this review, it is aimed to emphasize the importance of complementary feeding in terms of the risk of malnutrition among children and to give an example of current complementary feeding practices. It is stated that at the beginning of the 5 th month, infants neuromuscular development, digestive system, and renal solute load are suitable for complementary feeding. In addition to breast milk, complementary foods should include cereals, roots and tubers, legumes, nuts and seeds, dairy, meats, eggs, vegetables and fruits rich in vitamin A. Foods with allergy risk, such as eggs and peanuts should be tried for infants between 4 and 6 months. Along with breast milk, it is stated that 6-8-month olds are fed 2 or 3 times a day, and 9-11-months-old fed 3 or 4 times a day and should be paid attention to hunger and satiety signals. Complementary feeding should be started at 2 or 3 teaspoons and be increased considerably and transition should be made from pureed foods lumpy foods, finger foods and then chopped family foods until they are 12 months old. During the first year, vitamin D and iron micronutrient supplementation should be followed. It is recommended for infants to sip water instead of sugary drinks like fruit juices at meals and to introduce gluten to infants between 4 and 12 months. It is warned not to add sugar, salt and honey to the complementary feeding. To reduce the risk of malnutrition among children in Türkiye, complementary feeding should be given due significance.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132989262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Neglected Disease of Modern Society: Trauma. Outcomes and Prognostic Factors for Pediatric Trauma Patients in PICU","authors":"Adem Dursun, H. S. Durmuş, Serkan Özsoylu, B. Akyıldız","doi":"10.4274/tp.galenos.2022.14622","DOIUrl":"https://doi.org/10.4274/tp.galenos.2022.14622","url":null,"abstract":"","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128447296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evaluation of Local and Systemic Reactions to Subcutaneous House Dust Mite Allergen Immunotherapy","authors":"Z. Karali, Ş. Çekiç, Yağmur Hazal Şadırvan, Y. Canıtez, N. Sapan","doi":"10.4274/tp.galenos.2022.46320","DOIUrl":"https://doi.org/10.4274/tp.galenos.2022.46320","url":null,"abstract":"The of Local and Reactions Subcutaneous Dust ABSTRACT Objective: Allergen-specific immunotherapy is an effective treatment method that enables the development of immunotolerance against allergens in allergic rhinitis, asthma, and venom allergy. This study investigated the local and systemic reactions during subcutaneous house dust mite allergen immunotherapy. Methods: Injection-related local and systemic reactions of 45 patients who received subcutaneous mite immunotherapy were evaluated retrospectively. Results: Forty-five children, 15 (33.3%) females and 30 (66.4%) male were included in the study. A total of 582 injections were administered. A local reaction was observed in 23 (3.94%) of all injections and the systemic reaction was observed in only 1 (0.17%) injection. Sixteen (37.7%) of the children had local reactions during the immunotherapy process and 1 (2.2%) had a systemic reaction. Conclusion: Although subcutaneous mite immunotherapy is a safe treatment, it should only be applied in centers with appropriate emergency equipment and trained healthcare professionals due to possible","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117050452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angioedema Related to Infectious Mononucleosis","authors":"Duygu Lüleci Dağlı, H. Yüksel, S. Tunca, Ö. Yılmaz","doi":"10.4274/tp.galenos.2022.74745","DOIUrl":"https://doi.org/10.4274/tp.galenos.2022.74745","url":null,"abstract":"Ö. Angioedema Related to Infectious Mononucleosis. Trends ABSTRACT Epstein-Barr virus (EBV), a member of the Herpes-viridae family, is a microorganism could be present in various clinical presentations, from upper respiratory tract infection findings to asymptomatic liver function test elevation, from facial paralysis to angioedema. This case report has been prepared to emphasize EBV infection as a rare factor in the etiology of angioedema.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128243923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}