Trends in Pediatrics最新文献

Risk factors determining the development of food allergy intolerance at the first age in infants with atopic dermatitis 决定特应性皮炎婴儿在一岁时出现食物过敏不耐受的风险因素

Trends in Pediatrics Pub Date : 2024-03-30 DOI: 10.59213/tp.2024.113

Berfu Vurmaz Mammadov, P. Uysal

{"title":"Risk factors determining the development of food allergy intolerance at the first age in infants with atopic dermatitis","authors":"Berfu Vurmaz Mammadov, P. Uysal","doi":"10.59213/tp.2024.113","DOIUrl":"https://doi.org/10.59213/tp.2024.113","url":null,"abstract":"Objective: Very few studies have examined the risk factors for developing tolerance to food allergy in infants with atopic dermatitis (AD). To understand the risk factors for developing tolerance to food allergy in the first year in infants with atopic dermatitis and food allergy coexistence.Methods: Ninety-three infants were included in this retrospective study. Food allergy was detected using food-specific IgE, skin prick, and oral food challenge tests. The severity of the disease was evaluated using Scoring Atopic Dermatitis (SCORAD). Demographic parameters were recorded from medical records.Results: The rate of patients who tolerated food allergy in the first year was 61 (65.6%). The median age to tolerate food allergy was 12 (6-18 months). According to the SCORAD, 8 (8.6%) patients had mild, 50 (53.8%) had moderate AD, and 35 (37.6%) had severe AD. The median SCORAD value was 45.2 (35.2-54.6). There was no difference between the groups who tolerated food allergy and those who could not at the first age of life in terms of age, gender, gestational week, maternal age, and familial atopy history (p>0.05 for all). Egg allergy [p=0.035; OR:6.623 (CI:0.996-44.043)], parental atopy [p=0.024. OR:2.450 (CI:0.699-23.056], and AD severity [p=0.030. OR:1.240 (CI:1.001-22.105)] emerged as statistically significant variables at potential risk factors for food allergy intolerance in the first year.Conclusion: Egg allergy, parental atopy, and severity of atopic dermatitis emerged as potential risk factors for intolerance to food allergy in the first year of life in infants with atopic dermatitis and food allergy coexistence.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"67 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathogenic microorganisms and antimicrobial resistance patterns in the pediatric age group with urinary system infections 泌尿系统感染儿科年龄组的病原微生物和抗菌药耐药性模式

Trends in Pediatrics Pub Date : 2024-03-30 DOI: 10.59213/tp.2024.120

Güneş Işık, Pınar Öner

{"title":"Pathogenic microorganisms and antimicrobial resistance patterns in the pediatric age group with urinary system infections","authors":"Güneş Işık, Pınar Öner","doi":"10.59213/tp.2024.120","DOIUrl":"https://doi.org/10.59213/tp.2024.120","url":null,"abstract":"Objectives: Urinary system infections (UTIs) are among the most common infections affecting the pediatric age group. We aim to show the distribution of pathogenic microorganisms and antimicrobial resistance patterns of urinary tract infections (UTIs) and select the most appropriate antibiotherapy in the pediatric age group. Also, we wanted to determine signs and symptoms, predisposing factors, and imaging findings in UTIs.\u0000Material and Methods: In this study, the Elazığ Fethi Sekin City Hospital health registry system was screened retrospectively to obtain data about the results of urinalysis, urine culture tests, and urinary imaging findings of patients, who presented to the pediatric nephrology clinic with signs and symptoms of UTI between January 2020 and September 2021. The study population consisted of children aged 1 month to 18 years.\u0000Results: The study sample included 191 patients. Antimicrobial resistance of E. coli was seen at the highest level to ampicillin (55%), followed by amoxicillin (42%), trimethoprim-sulfamethoxazole (TMP-SMX) (36%), and cefuroxime (35%). The antimicrobial resistance of Klebsiella pneumoniae was seen most frequently in patients treated with ampicillin (100%), amoxicillin (50%), ceftazidime (31%), and nitrofurantoin (31%). The antimicrobial resistance of Proteus mirabilis was seen mostly in cases that received nitrofurantoin (88%), and TMP-SMX (55%). Enterobacter aerogenes demonstrated minimal antimicrobial sensitivity to ampicillin (66%), amoxicillin (33%), and nitrofurantoin (33%) in decreasing order of frequency.\u0000Conclusions: The rate of resistance to ampicillin is very high in Klebsiella pneumoniae and in Enterobacter spp and rates of antimicrobial resistance to cephalosporin, TMP-SMX, and nitrofurantoin are increasing. The rational use of antibiotics is a globally important issue.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"58 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sterile abscess formation with two different GnRH analogues: Three case reports 两种不同 GnRH 类似物的无菌脓肿形成：三份病例报告

Trends in Pediatrics Pub Date : 2024-03-30 DOI: 10.59213/tp.2024.117

Gülin Karacan Küçükali, Şervan Özalkak, Havva Nur Peltek Kendirci, İlknur Bostancı, Ş. Savaş Erdeve, S. Çetinkaya

{"title":"Sterile abscess formation with two different GnRH analogues: Three case reports","authors":"Gülin Karacan Küçükali, Şervan Özalkak, Havva Nur Peltek Kendirci, İlknur Bostancı, Ş. Savaş Erdeve, S. Çetinkaya","doi":"10.59213/tp.2024.117","DOIUrl":"https://doi.org/10.59213/tp.2024.117","url":null,"abstract":"Gonadotropin-releasing hormone analogues (GnRHa) have been used safely for many years in the treatment of precocious puberty. Although rare, pain, swelling, and erythema at the injection site are known local side effects in patients receiving GnRHa treatment and are temporary. Sterile abscess development is also one of the rare local side effects. Here, we present three cases of treatment failure due to the development of sterile abscesses after GnRHa therapy.\u0000Sterile abscesses developed in three girls who were followed up with a diagnosis of precocious/progressive puberty respectively in 4., 12. and 5. doses of GnRHa treatment. In the first case, a sterile abscess recurred despite the therapy being switched to another preparation. We had to follow up without treatment in three of our cases.\u0000Although sterile abscess is a rare side effect, it is essential as it causes patients to be left untreated. In these cases, the drug’s active substance accumulates in the localization at the sterile abscess and cannot be absorbed, so it cannot enter the systemic circulation. Therefore, puberty cannot be suppressed. Also, a remaining scar is annoying for patients and their families.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"26 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140361808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutcracker syndrome in childhood 儿童胡桃夹子综合征

Trends in Pediatrics Pub Date : 2024-03-30 DOI: 10.59213/tp.2024.111

Emine Gülşah Özdemir, B. Gülhan

{"title":"Nutcracker syndrome in childhood","authors":"Emine Gülşah Özdemir, B. Gülhan","doi":"10.59213/tp.2024.111","DOIUrl":"https://doi.org/10.59213/tp.2024.111","url":null,"abstract":"Nutcracker phenomenon (NP) is defined as the compression of the left renal vein, often occurring between the aorta and the superior mesenteric artery (SMA). Patients with symptoms associated with the Nutcracker anatomy are called “Nutcracker syndrome” (NCS). Renal vein compression results in venous congestion, outlet obstruction, and increased pressure in the left renal vein. The clinical manifestations of NCS in children vary widely depending on the severity of compression. It can range from being asymptomatic to presenting with intermittent or persistent micro or macrohematuria, orthostatic proteinuria, renovascular hypertension, abdominal pain, left-sided flank pain, dysmenorrhea, pain in the testicles or scrotum, and left varicocele. Hematuria, proteinuria, and flank pain are prevalent symptoms. The anatomical and physiological degree of compression of the left renal vein can be diagnosed through Doppler ultrasound (DUS), computer tomography (CT) scan, or magnetic resonance imaging (MRI). In cases with mild symptoms, conservative treatment is an appropriate option, and ACE inhibitors can be used for patients with proteinuria. In more severe cases where conservative approaches and medical treatment fail to yield satisfactory results, endovascular, laparoscopic, or open surgical interventions are employed.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"41 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Importance of Thyroid Function Tests in a Patient Presenting with Precocious Menarche: Van Wyk Grumbach Syndrome 甲状腺功能检查在月经初潮提前患者中的重要性:Van Wyk Grumbach综合征

Trends in Pediatrics Pub Date : 2022-12-28 DOI: 10.4274/tp.2022.86548

Ö. Köprülü, S. Acar

引用次数: 1

Late-effects of Chemoradiotherapy on Growth and Puberty in Survivors of Childhood Acute Lymphoblastic Leukemia 放化疗对儿童急性淋巴细胞白血病幸存者生长和青春期的后期影响

Trends in Pediatrics Pub Date : 2022-12-28 DOI: 10.4274/tp.2022.43043

Sevgi Bilgic Eltan, A. Akçay, Elvan Bayramoğlu, M. Eltan, T. Akçay, Z. Şalcıoğlu, G. Aydogan

引用次数: 0

Serum Vitamin D and B12 Levels in School-aged Children and Adolescents with Frequent Primary Headache Attacks 常发头痛的学龄儿童和青少年血清维生素D和B12水平

Trends in Pediatrics Pub Date : 2022-12-28 DOI: 10.4274/tp.2022.13008

G. D. Kaya Özçora, Elif Söbü, M. Canpolat, F. Kardaş, M. Kendirci, H. Gümüş, H. Per, S. Kumandas

引用次数: 0

Can Vitamin B12 Deficiency Really Cause Vasovagal Syncope? Retrospective Analysis of 469 Pediatric Vasovagal Syncope Cases 维生素B12缺乏真的会导致血管迷走神经性晕厥吗?469例小儿血管迷走神经性晕厥回顾性分析

Trends in Pediatrics Pub Date : 2022-12-28 DOI: 10.4274/tp.2022.49469

S. Sunkak, M. Argun

引用次数: 0

Etiological Factors of Opsoclonus Myoclonus Ataxia Syndrome: A Single Center Experience with Eight Children 斜阵肌阵挛性共济失调综合征的病因学因素:八个儿童的单中心经验

Trends in Pediatrics Pub Date : 2022-12-28 DOI: 10.4274/tp.2022.29292

Veysel Gök, Gülsüm Gümüş, Habibe Selver Durmuş, Ekrem Ünal, H. Gümüş, M. Karakükçü, Ayşe Kaçar Bayram, H. Per

引用次数: 0

Management of Foreign Body Ingestion in Children: A Single-center Experience 儿童异物摄入的管理:单中心经验

Trends in Pediatrics Pub Date : 2022-12-28 DOI: 10.4274/tp.2022.58561

A. Yücel, Ö. Yaz

{"title":"Management of Foreign Body Ingestion in Children: A Single-center Experience","authors":"A. Yücel, Ö. Yaz","doi":"10.4274/tp.2022.58561","DOIUrl":"https://doi.org/10.4274/tp.2022.58561","url":null,"abstract":"Objective: Foreign body (FB) ingestion is frequently encountered in childhood, and although the clinical results are often benign, it has high morbidity and mortality rates. Although guidelines for managing these children are available, there are still controversial aspects of the treatment recommendations. This study aimed to evaluate the treatment options for children who swallow FBs. Methods: The study included 439 patients admitted with FB ingestion. Demographic and clinical features, type, size and localization of FB, treatment approach, and the timing of endoscopy were retrospectively scanned from hospital records. Results: Most patients were male (58.3%) and 69.7% of the patients were aged <5 years. The most common symptom (42.3%) was nausea and vomiting and 82.5% of the patients were asymptomatic. The most common localization was the intestines (59.7%). While 84.1% of swallowed FBs came out with a spontaneous passage without complications, the endoscopic removal procedure was successful at the rate of 91.8%. The most frequently swallowed FB was coins (39.6%). Spontaneous elimination rates were higher for small coins and endoscopic removal rates were higher for large coins (p<0.001). The rate of emergency endoscopy was significantly higher in cases who swallowed a 2.6 cm coin (p<0.001). It was found that all sharp/pointed objects located in the intestine on admission came out spontaneously without complications. Sharp/pointed objects and button batteries located in areas accessible by esophagogastroduodenoscopy were more frequently removed using the endoscopic technique (p<0.001). In the cases with the ingestion of a single magnet or superabsorbent FB (giant growing toys), the FB came out with spontaneous passage without any adverse clinical outcome. Conclusion: It can be suggested that this study of a large sample, showing the management of FBs without complications, will be of guidance in clarifying controversial aspects of the treatment.","PeriodicalId":225135,"journal":{"name":"Trends in Pediatrics","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123010447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0