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The Brown University Child & Adolescent Psychopharmacology Update最新文献

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Nalmefene study: A faster alternative to naloxone 纳美芬研究：纳洛酮的快速替代品
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-04-15 DOI: 10.1002/cpu30857
Alison Knopf
{"title":"Nalmefene study: A faster alternative to naloxone","authors":"Alison Knopf","doi":"10.1002/cpu30857","DOIUrl":"https://doi.org/10.1002/cpu30857","url":null,"abstract":"<p>In the first head-to-head study of nalmefene nasal spray (OPVEE is the trade name) vs. naloxone to reverse opioid overdose conducted in volunteers, researchers found that nalmefene worked faster than a 4 milligram (mg) dose of naloxone. It worked much faster, in fact, 2.7 mgs of OPVEE reversed respiratory depression within 5 minutes, compared to 20 minutes for 4 mgs of naloxone. The opioid that was given to the volunteers was remifentanil, a synthetic opioid.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 5","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140552073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NIDA: More than 11% of high school seniors use delta-8, the unregulated THC NIDA：超过 11% 的高中生使用未受管制的四氢大麻酚 delta-8
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-04-15 DOI: 10.1002/cpu30858
Alison Knopf
{"title":"NIDA: More than 11% of high school seniors use delta-8, the unregulated THC","authors":"Alison Knopf","doi":"10.1002/cpu30858","DOIUrl":"https://doi.org/10.1002/cpu30858","url":null,"abstract":"<p>About 11% of 12th graders have used delta-8 tetrahydrocannabinol (THC) in the past year, according to an analysis of last year's Monitoring the Future Study which is conducted by the National Institute on Drug Abuse (NIDA).</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 5","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140552074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Teens prescribed stimulants for ADHD not likely to have later drug misuse 开兴奋剂治疗多动症的青少年日后不太可能滥用药物
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-04-15 DOI: 10.1002/cpu30862
Alison Knopf
{"title":"Teens prescribed stimulants for ADHD not likely to have later drug misuse","authors":"Alison Knopf","doi":"10.1002/cpu30862","DOIUrl":"https://doi.org/10.1002/cpu30862","url":null,"abstract":"","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 5","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140552078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
All rescue medications are needed in fentanyl era 芬太尼时代需要所有抢救药物
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30850
Alison Knopf
{"title":"All rescue medications are needed in fentanyl era","authors":"Alison Knopf","doi":"10.1002/cpu30850","DOIUrl":"https://doi.org/10.1002/cpu30850","url":null,"abstract":"<p>Stories of overdose deaths greatly outnumber stories of withdrawal precipitated by the use of rescue medications such as naloxone. In fact, the illicit fentanyl supply is so strong that the standard dose of intranasal naloxone — 4 milligrams — is no longer enough in most cases, unless there is oxygen supplementation (see FDA urges higher naloxone doses in fentanyl era, <i>CPU</i> March 2024; https://onlinelibrary.wiley.com/doi/full/10.1002/cpu30843). Most reversals of overdose require at least two doses and waiting in between those doses can be fatal. Brain damage from oxygen loss can also occur. Yet the harm reduction community continues to fret about naloxone and other rescue medications causing precipitated withdrawal.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SAMHSA overdose toolkit contradicts evidence on doses needed SAMHSA 药物过量工具包与所需剂量的证据相矛盾
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30853
Alison Knopf
{"title":"SAMHSA overdose toolkit contradicts evidence on doses needed","authors":"Alison Knopf","doi":"10.1002/cpu30853","DOIUrl":"https://doi.org/10.1002/cpu30853","url":null,"abstract":"<p>A “toolkit” (federalese for a brochure) on overdose prevention and rescue from the Substance Abuse and Mental Health Services Administration (SAMHSA) issued last month has outdated recommendations for overdose rescue medications. The toolkit, which SAMHSA released at last month's annual CADCA conference, calls for giving one dose (4 mg) of naloxone initially, followed by a second dose two or three minutes later. It also says that studies show increased doses of naloxone are not necessary in the fentanyl era.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"6-7"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Researchers find maternal use of ADHD stimulants safe during pregnancy 研究人员发现孕妇在孕期使用多动症兴奋剂是安全的
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30854
Alison Knopf
{"title":"Researchers find maternal use of ADHD stimulants safe during pregnancy","authors":"Alison Knopf","doi":"10.1002/cpu30854","DOIUrl":"https://doi.org/10.1002/cpu30854","url":null,"abstract":"","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient Information Sheet 患者信息表
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30856
{"title":"Patient Information Sheet","authors":"","doi":"10.1002/cpu30856","DOIUrl":"https://doi.org/10.1002/cpu30856","url":null,"abstract":"<p>Metformin hydrochloride, extended-release (XR) (generic) — Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet (brand)</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-harming individuals admitted to hospital are high risk for psychosis 入院治疗的自残者是精神病的高危人群
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30852
Alison Knopf
{"title":"Self-harming individuals admitted to hospital are high risk for psychosis","authors":"Alison Knopf","doi":"10.1002/cpu30852","DOIUrl":"https://doi.org/10.1002/cpu30852","url":null,"abstract":"<p>That there is a strong relationship between psychosis and self-harm is not in question. However, most of the research conducted has been on individuals already diagnosed with a psychotic disorder. So researchers wanted to look at whether self-harm can be a marker for future psychosis.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ADHD medications for young children 幼儿多动症药物
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30855
{"title":"ADHD medications for young children","authors":"","doi":"10.1002/cpu30855","DOIUrl":"https://doi.org/10.1002/cpu30855","url":null,"abstract":"<p>Attention-deficit hyperactivity disorder, also known as ADHD, is a condition that often begins between ages 3 and 6, according to the National Institute of Mental Health. And it's not just a childhood disease. ADHD may continue through the teenage years and into adulthood.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CM management, best treatment for stimulant disorder, still on the ropes 中药管理是治疗兴奋剂紊乱症的最佳方法，但仍遥遥无期
The Brown University Child & Adolescent Psychopharmacology Update Pub Date : 2024-03-12 DOI: 10.1002/cpu30851
Alison Knopf
{"title":"CM management, best treatment for stimulant disorder, still on the ropes","authors":"Alison Knopf","doi":"10.1002/cpu30851","DOIUrl":"https://doi.org/10.1002/cpu30851","url":null,"abstract":"<p>Contingency management (CM) is the only proven treatment for stimulant use disorder. It is based on paying people money for staying off stimulants, but the reward has to be much bigger than the $75 a year allowed under federal law (See Contingency management, best treatment for stimulants, essential with fentanyl; <i>CPU</i> April 2023; https://onlinelibrary.wiley.com/doi/10.1002/cpu.30761). In February, top researchers again called on the federal government to pay attention to this problem, raising the cap. Methamphetamine-involved deaths increased from 545 in 1999 to 32,353 in 2021. Of the more than 100,000 illicit drug deaths in 2021, two-thirds involved fentanyl, but almost half of the fentanyl-involved deaths included the co-use of methamphetamine, cocaine, or other stimulants..</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"26 4","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140114292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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