{"title":"Loneliness in early adolescence associated with increased risk for mental disorders","authors":"Alison Knopf","doi":"10.1002/cpu.31053","DOIUrl":"https://doi.org/10.1002/cpu.31053","url":null,"abstract":"<p>Persistent loneliness is associated with many mental health problems, including psychotic experiences in adolescents, but the risk may be mitigated if the loneliness ends. Interventions targeting loneliness may work, but more research is needed, researchers wrote.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 4","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temperament in young children associated with specific neuronal networks","authors":"Alison Knopf","doi":"10.1002/cpu.31054","DOIUrl":"https://doi.org/10.1002/cpu.31054","url":null,"abstract":"<p>Neuronal network functional connectivity — representing communication within brain regions, which can be measured by EEG – is important in the understanding of early temperament. This is especially true for attention and control networks, which indicate that early interventions could be aimed at at-risk children.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 4","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FDA requests removal of suicide warnings from two GLP-1 labels","authors":"","doi":"10.1002/cpu.31056","DOIUrl":"https://doi.org/10.1002/cpu.31056","url":null,"abstract":"<p>The Food and Drug Administration (FDA) has requested that manufacturers of some Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 R A) remove warnings about suicidal behavior and ideation from labels. The request in a January 13, 2026 letter is an “update” on the FDA's ongoing evaluation of this issue. In the January letter, the FDA stated that it “did not identify an increased risk of suicidal ideation or behavior with the use of GLP-1 RA medications.” Below is the public information from the letter.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 4","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychotic-like experiences found predictive of half of mental disorders","authors":"Alison Knopf","doi":"10.1002/cpu.31051","DOIUrl":"https://doi.org/10.1002/cpu.31051","url":null,"abstract":"<p>Teens who have psychotic-like experiences (PLEs) are more likely than teens who don't to develop psychotic and nonpsychotic mental illness, researchers have found. They urge that high-risk adolescents be screened for PLEs as a predictor of mental disorders.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 4","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contraindicated psychotropic medication use widespread","authors":"Alison Knopf","doi":"10.1002/cpu.31052","DOIUrl":"https://doi.org/10.1002/cpu.31052","url":null,"abstract":"<p>One in four youth were exposed to potential contraindicated or major drug-drug interactions (DDIs) during the two-decade period ending in 2020, researchers have found. They urge that studies be conducted focusing on medication safety, effectiveness, and DDI risks of psychotropic medications in youth.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 4","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2024 leucovorin paper retracted, drug pending FDA approval for cerebral folate deficiency","authors":"Alison Knopf","doi":"10.1002/cpu.31055","DOIUrl":"https://doi.org/10.1002/cpu.31055","url":null,"abstract":"","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FDA facing challenges: GAO","authors":"","doi":"10.1002/cpu.31049","DOIUrl":"https://doi.org/10.1002/cpu.31049","url":null,"abstract":"<p>Last month the Government Accountability Office (GAO) released a report highlighting problems faced by the Food and Drug Administration (FDA) due to funding and staffing and operational challenges over the past decade.</p>","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 3","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assess the family to help the child – and the family","authors":"Alison Knopf","doi":"10.1002/cpu.31047","DOIUrl":"https://doi.org/10.1002/cpu.31047","url":null,"abstract":"","PeriodicalId":22496,"journal":{"name":"The Brown University Child & Adolescent Psychopharmacology Update","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}