Tao te Ching最新文献_第2页

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Tao te Ching Pub Date : 2019-04-04 DOI: 10.7551/mitpress/11741.003.0008

Bernardo Kucinski

{"title":"5","authors":"Bernardo Kucinski","doi":"10.7551/mitpress/11741.003.0008","DOIUrl":"https://doi.org/10.7551/mitpress/11741.003.0008","url":null,"abstract":"32 High quality reference genomes are vital to study the impact of sequence variation on genome 33 structure and function. Recent advancements in long-read sequencing have greatly improved 34 the quality of de novo genome assemblies and enhanced the detection of sequence variants at 35 the scale of hundreds or thousands of bases. The nematode Caenorhabditis elegans is a 36 powerful model system for both genetic and evolutionary studies. Comparisons between two 37 diverged wild isolates, the Bristol and Hawaiian strains, have been widely utilized in the analysis 38 of small genetic structural variations in C. elegans . The reference genomes most widely used 39 for these isolates were assembled using short read sequencing, which makes the detection of 40 large structural variations challenging. To comprehensively detect both large and small 41 structural variations as well as sequence divergence in the Hawaiian and Bristol C. elegans 42 isolates, we generated de novo genome assemblies for each strain using both long- and short- 43 read sequencing. With these assemblies, we annotate over 3.1Mb of sequence divergence 44 between the Bristol and Hawaiian isolates: 337,584 SNPs, 94,503 small insertion-deletions 45 (<50bp), and 4,334 structural variations (>50bp). By comparing our de novo genome assembly 46 of the Bristol isolate to the VC2010 Bristol assembly, we also reveal that lab lineages display 47 1,162 SNPs, 1,528 indels, as well as 897 structural variations- over 2Mb of total variation. Our 48 work highlights both the importance of using long-read sequencing in de novo genome 49 assembly to identify the total genetic variation between strains and the underappreciated impact 50 of long-term laboratory cultivation on genome structure.","PeriodicalId":224723,"journal":{"name":"Tao te Ching","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133291745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INTRODUCCIÓN 导言

Tao te Ching Pub Date : 2019-03-25 DOI: 10.18356/02d0286b-es

Margarita Vidal-Lizama

引用次数: 0

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Tao te Ching Pub Date : 2018-12-31 DOI: 10.1525/9780520953703-073

Ryo K. awamura, K. Tuji, Iwao Nakagawa, Kazukiyo Toriyama

引用次数: 29

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Tao te Ching Pub Date : 2018-12-31 DOI: 10.1525/9780520953703-067

G. Marini

{"title":"66","authors":"G. Marini","doi":"10.1525/9780520953703-067","DOIUrl":"https://doi.org/10.1525/9780520953703-067","url":null,"abstract":"The paper focuses on the artistic work of Moses Levy (Tunis, 1885 Viareggio, 1968), painter and printmaker active in Italy, Tunisia and Paris. A peculiar figure of cosmopolitan painter, whose father was British and the mother Italian, and whose art eludes attempts at univocal classification. On the contrary, it remains emblematic of the fruitfulness made possible by the encounter between different artistic traditions, as well as the reciprocal enrichment offered by the plurality of cultures. Deeply linked by birth to the Jewish community in Tunis, he moved to Italy at a very young age, where he came into contact with the major exponents of the Tuscan school of painting around the turn of the century, starting with Giovanni Fattori. Constantly commuting between the two shores of the Mediterranean, he became an example of dialogue between different worlds, between his African roots, his Tuscan upbringing, his French-speaking culture and his stays in Paris, where he met Chagall and Picasso and could not fail to find a natural identification with Matisse’s pure rhythms and solar charge. A regular exhibitor at the Salons Tunisiens, in 1936 he was a co-founder of the Le Quatre group and later one of the promoters of the École de Tunis. Thus, the local artists saw in Levy the master who had been able to promote the birth of a modern art that was representative of Tunisian culture and people, but free from any easy Orientalist stereotype or folkloric flavour.","PeriodicalId":224723,"journal":{"name":"Tao te Ching","volume":"449 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116332185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 43

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Tao te Ching Pub Date : 2018-12-31 DOI: 10.2307/j.ctv1g4rv2h.78

D. Correia, M. Delgado, Sofia Costa Dinis

引用次数: 40

67 67

Tao te Ching Pub Date : 2018-12-31 DOI: 10.1525/9780520953703-068

引用次数: 30

40 40

Tao te Ching Pub Date : 2018-08-14 DOI: 10.1525/9780520953703-041

Livy

引用次数: 0