I. N. Swastika, Ni Ketut Ristiani, Adrian Wiryanata Gorintha, Agung Wiwiek Indrayani
{"title":"Potensi Formulasi Self Microemulsifying Drug Delivery System (SMEDDS) Ekstrak Biji Kedelai (Glycine soja) Terhadap Penurunan Kolesterol pada Penyakit Jantung Koroner","authors":"I. N. Swastika, Ni Ketut Ristiani, Adrian Wiryanata Gorintha, Agung Wiwiek Indrayani","doi":"10.14710/jekk.v6i2.12190","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.12190","url":null,"abstract":"Background: Coronary heart diseases (CHD) is a disorder that caused by blockage of coronary arteries due to the process of atherosclerosis which disrupts the blood supply to the heart muscle. According to Sample Registration System (SRS) Indonesia in 2014, CHD is a second highest cause of death after stroke that is 12,9% of all cause of death in Indonesia. Therefore, this study aims to examining the effect of soybean extract encapsulated with Self Microemulsifying Drug Delivery System (SMEDDS) on LDL levels in coronary heart model rats. Based on various study, isoflavone aglycone genistein is the main flavonoid in soybean seed that has potential as an antioxidant. To increase bioavailability of aglycone isoflavones, a SMEDDS is needed. In this regard, the purpose of this reseach is to examine the potential of soybean seed (Glycine soja) extract to reduced cholesterol in CHD.Methods: The method used is a literature review with literature sources in the form of relevant articles from the search engines, namely Google Scholar, Pubmed, ScienceDirect, and Research Gate. Inclusion criteria included journals containing the keywords “soybean (Glycine soja)”, “Coronary Heart Disease”, “SMEDDS”, and “genistein isoflavone aglycone”.Result: Isoflavone aglycone as an potential antioxidant that is able to bind free radicals and and also lowering LDL, Triglycerides, and glucose levels in hyperglycemic states and increasing HDL.Conclusion : Soybean seed extract with SMEDDS encapsulation have a potential to decrease LDL level in coronary heart disease.","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134569668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analisis Faktor Risiko Kejadian HIV/AIDS Berbasis Perilaku Manusia Di Kabupaten Madiun Tahun 2018","authors":"Puri Ratna Kartini","doi":"10.14710/jekk.v6i2.9510","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.9510","url":null,"abstract":"Background: HIV / AIDS is a behavior-based disease. The HIV epidemic is a serious problem and challenge to public health in the world both in developed and developing countries such as Indonesia. In Asia, the factors driving the HIV / AIDS epidemic are three high-risk behaviors, namely unprotected commercial sex, sharing syringes in drug users and sex between unprotected men. This study is an observational-analytic study that aims to analyze the influence of human behavior factors included in the practice of free sex, alcohol consumption practices, drug use practices, attitudes and practices of weak religious teachings against the incidence of HIV / AIDS in Madiun Regency.Methods: The research design used was case control, with a purposive sampling technique. Data was taken through interviews to respondents using questionnaires and analyzed using logistic regression tests. This research was conducted in the working area of the Madiun District AIDS Eradication Commission (KPAD) for 6 months, starting from January to June 2018. The case group in this study were 20 HIV-AIDS sufferers selected and the control group was family / neighboring of the HIV / AIDS sufferers who does not suffer from HIV / AIDS as many as 20 people.Result: The results of this study show that the practice of injecting drug use (p> 0.005 which is 1,000) and alcoholic consumption practices (p> 0.005 which is 0.355) is not a risk factor for HIV / AIDS in Madiun Regency. Whereas the risky sex practices and weak religious teaching practices are the risk factors for HIV / AIDS in Madiun Regency which value of p is 0.017 and 0.021.Conclusion : Thus there is a need for counseling efforts about safe sex and to increase faith and piety in order to reduce the risk of transmission of HIV / AIDS in Madiun regency. ","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116424921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Relationship between Exclusive Breastfeeding and Diarrhea in Under Six Months Infants in 2017 (Analysis of Indonesian Health Demography Data Survey 2017)","authors":"Fikriya Rusyda, S. Ronoatmodjo","doi":"10.14710/jekk.v6i2.11815","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.11815","url":null,"abstract":"Background: Diarrhea is the main cause of malnutrition in underfive children. One of the efforts to prevent diarrhea in infants is exclusive breastfeeding. Exclusive breastfeeding is infant that receives only breast milk without any additional consumption from 0 to 6 months. Under six months infant who are not exclusively breastfed have a higher risk of developing diarrhea than those who are exclusively breastfed.Methods: This study aims to determine the relationship between exclusive breastfeeding and the incidence of diarrhea in under six months infants in Indonesia. This study analyze secondary data from the 2017 Indonesian Demographic and Health Survey. The sample in this study consist of all live infants aged 0-6 months born to women aged 15-49 years in Indonesia who were successfully interviewed and had a complete answer (no answer missing). After weighting, 1898 samples were obtained.Result: The result found that the proportion of diarrhea incidence in Indonesia is 9.1%. Meanwhile of all infants, 36% were not exclusively breastfed. The results showed that there was a significant relationship between infants who were not exclusively breastfed and diarrhea incidence in Indonesia after adjusted by mother's education level, maternal employment status, mother’s economic level, area of residence, and latrine ownership (PR = 2.12, 95% CI = 1.46-3.07).Conclusion : Infants who were not exclusively breastfed increase the risk for diarrhea. Therefore it is necessary to have a program to increase the coverage of exclusive breastfeeding. The program can take the form of counseling by health workers in health services.","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126720900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hubungan Tingkat pengetahuan dan Sikap dengan Praktik Pencegahan COVID-19 pada Masyarakat Pengguna Internet di Kota Semarang","authors":"Dwi Sutiningsih","doi":"10.14710/jekk.v6i2.11886","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.11886","url":null,"abstract":"Background: The city of Semarang was ranked first in the highest confirmed case of COVID-19 in Central Java. Various control efforts have been made to stop the spread of this disease through government regulations and behavioral interventions in the community that depend on the compliance of the community itself. This study aims to analyze the level of health literacy, level of knowledge, attitudes and prevention practices related to COVID-19 in the general public of Semarang City.Methods: This study uses an observational analytic method with a cross-sectional approach which is carried out on the people of Semarang City. Data was collected through a google form questionnaire which was distributed online through social media from October 12 to November 9, 2020 and managed to collect 407 respondents from 16 sub-districts in Semarang City. The questionnaire consists of 42 questions covering the level of knowledge, attitudes and practices of prevention against COVID-19. Data were analyzed by univariate and bivariate with Chi-square statistical analysis.Result: The knowledge of internet users in Semarang City regarding COVID-19 was mostly good (50.1%), the attitudes and practices of preventing COVID-19 were also mostly good (56.5% and 50.6%). There was a significant relationship between the level of knowledge about COVID-19 and COVID-19 prevention practices (p-value=0,001). There was a relationship between attitudes related to COVID-19 and COVID-19 prevention practices (p-value=0.001).Conclusion : There is a relationship between the level of knowledge and attitudes towards COVID-19 prevention practices in the internet user community in Semarang City. Improved health education is needed to improve literacy and prevention practices for COVID-19.","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121141882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Maryanto, M. P. Tambunan, Isranto Handoyo Putra
{"title":"Managing The COVID-19 Pandemic in The Community-Based Mountain Eruption Zone, Cangkringan Sub-District, in Yogyakarta","authors":"M. Maryanto, M. P. Tambunan, Isranto Handoyo Putra","doi":"10.14710/jekk.v6i2.10891","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.10891","url":null,"abstract":"Background: First case in Indonesia was reported in March 2, 2020 and until November, it has infected more than 400.000 people, with more than 300.000 recovered and 15.000 deaths in total. Especially in Cangkringan District and surrounding area, the latest natural disaster is happening in the midst of a COVID-19 pandemic that is eruption of Mount Merapi which encourage local government and outposts to prepare camps for people nearby who suffered from Mount Merapi eruption. Meanwhile, in evacuation camp, the chance of infected by COVID-19 is high and it is a main problem and a purpose of this research.Methods: Methods that is conducted in this research by obtaining vulnerability level data against the outbreak and making a probability map of virus transmission mainly in the eruption red zone.Result: The outcome of this research is COVID-19 mitigation map within eruption red zone of this regency and recommendations about how to control the outbreak among refugees.Conclusion: Therefore, evacuation can be conducted in the midst of pandemic situation because the transmission case is low.","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126424805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle Christo, L. Saraswati, Ari Udiyono, Dwi Sutiningsih
{"title":"Mixed Methods Systematic Review : Kejadian Cabin Fever Selama Pembatasan Sosial Saat Penyebaran Penyakit Sars, Mers Dan Covid-19","authors":"Michelle Christo, L. Saraswati, Ari Udiyono, Dwi Sutiningsih","doi":"10.14710/jekk.v6i2.10660","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.10660","url":null,"abstract":"Background: SARS, MERS and Covid-19 are the most dangerous viruses among the Human Coronavirus (HCoV). The spreading of those diseases could cause cabin fever due to social restrictions as the control and prevention efforts. This study aims to map the impact of cabin fever during HCoV pandemic by the characteristic population and its causing factors.Methods: A mixed method systematic review was conducted in five databases and its keywords were determined using MeSH (Medical Subject Headings). All articles were assessed after passed the last process (included). There are 11 articles included and 3 of them rated as strong quality. The findings were grouped into themes related to population characteristics and causative factors.Result: The result shows among 4 themes of population characteristic, college student shows more than five symptoms of cabin fever. Out of all the causing factors, quarantine and social distancing shows more than five symptoms of cabin fever.Conclusion: This review proves that cabin fever can occurs during the outbreak, epidemics and pandemics so, psychological treatment in the communities is needed during the spreading of the viruses. The treatment must be right because the symptoms of cabin fever differ according to population and the causes.","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121607291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obesity and Severity COVID-19 : Literature Review Study","authors":"Disa Hijratul Muharramah, N. Prihartono","doi":"10.14710/jekk.v6i2.11662","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.11662","url":null,"abstract":"Background: Coronavirus disease (COVID-19) caused by SARS-CoV 2 (Severe Acute Respiratory Syndrome) has spread worldwide and infected more than 180 million confirmed cases and 3,9 million deaths. The clinical manifestations of COVID-19 range from asymptomatic or mild infection to severe. Previous reports identified that obesity is associated with the condition of a person infected with COVID-19 develop into severe. This study aims at examining the risk of severity COVID-19 associated with obesity Methods: This study was conducted a literature review method. There are ten articles obtained from online databases at Pubmed, Google Schoolar and the Wiley Online Library.Result: The results of various studies using cohort and cross-sectional study designs show that obesity has a statistically significant association with increasing risk for the severity of COVID-19. Obese individuals infected with COVID-19 suffer severe and critical symptoms that impact patients admitted to ICU, intubation and death.Conclusion : Obesity increase the risk for severity of COVID-19. Maintain healthy life style, including routine exercise, choice of healthy food and routine medical checkup may reduce the risk of severity of COVID-19","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"163 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131487283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Nasyia Fahira, Estro Dariatno Sihaloho, A. Y. Siregar
{"title":"Pengaruh Konsumsi Air dan Keberadaan Fasilitas Sanitasi terhadap Angka Diare pada Anak-Anak di Indonesia","authors":"Nadia Nasyia Fahira, Estro Dariatno Sihaloho, A. Y. Siregar","doi":"10.14710/jekk.v6i2.10871","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.10871","url":null,"abstract":"Background: As a developing country, Indonesia maintains a low level of welfare for hygiene, as exemplified by Indonesia’s poor access facilities to clean water and lack of proper sanitation for households. Meanwhile, a proper supply of water and sanitation will help in reducing morbidity and mortality rates of diarrhea in children. Other risk factors such as socio-economic and socio-demographic conditions, helps improving the quality of life of households, thus lowering the risk of various diseases, including diarrhea.Methods: This study uses a Logistic Regression Analysis (Logit) model with Cross-sectional design using data collected from the 5th wave of the Indonesian Family Life Survey (IFLS-5) in 2014. The study population was children aged 2-10 years with a total of 2446 observations.Result: The result shows that there was a relationship between father's education in elementary school level (p=0.013), father's education in junior high school level (p=0.015), father's education in high school level (p=0.001), father's education at the university level (p=0.012), income (p=0.051), children’s age (p=0.000), and children’s gender (p=0.033) with the rate of diarrhea in children.Conclusion: This research concludes that water consumption factors (sources of drinking water, drinking water boiling process before consumption) and sanitation facilities factors (household toilet types) have insignificant results on the diarrhea rate of children in urban areas of Indonesia. However, socio-economic factors (fathers' education and household income) and socio-demographic factors (children’s gender and children’s age) have a significant effect on the diarrhea rates of children in urban areas of Indonesia.","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"28 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120911607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Six Minute Walk Test as a Marker of Functional Capacity in Hypertensive Patients","authors":"S. Purwowiyoto, S. P. Surya","doi":"10.14710/jekk.v6i2.9742","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.9742","url":null,"abstract":"Background: Currently, hypertension becomes one of the leading issues not only for medical community but also to the broader societies. Even though hypertension could be symptomatic, in most case it didn’t until the devastating complications shows up. Functional capacity is a simple tool based on our daily activity. The six-minute walk test could be one of the simplest ways in measuring functional capacity. Six-minute distance as the outcome of this test could be potentially a marker for functional capacity in hypertensive group compare to non-hypertensive group.Methods: This is a case control study with 34 female participants in six-minute walking test.Result: There are no significant different of age, height, weight, and body max index between those groups. The six-minute walking distance drastically difference between hypertensive and non-hypertensive group, 306m and 367m respectively with p-value < 0,01. Heart rate pre-test also statistically different between control group and case group. (75 bpm and 94 bpm, p-value = 0,027) Post-test blood pressure is notably distinctive between two groups. Additionally, systolic blood pressure post-test lower than initial value. Hypertension alters human functional capacity ominously.Conclusion : The six-minute walk test could be applied as simple functional capacity marker in hypertension subject. ","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121022043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hubungan Tingkat Pengetahuan dan Tingkat Kepatuhan Minum Obat dengan Tingkat Kekambuhan Lupus Eritematosus Sistemik","authors":"Dinda Sinta Rahayu, Ari Udiyono, L. Saraswati","doi":"10.14710/jekk.v6i2.9930","DOIUrl":"https://doi.org/10.14710/jekk.v6i2.9930","url":null,"abstract":"Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with varied manifestations and characterized by recurring flares. Lack of disease knowledge and non-compliance with drug therapy are an important cause of not achieving treatment targets and worsening lupus symptoms.Methods: This research is a descriptive study with a cross-sectional approach. The research method is quantitative. The sample in this study were 136 patients who came to examine themselves at Central-General Hospital in Semarang City. The sampling technique used in this study was total sampling. This study used a questionnaire to determine the variables studied.Result: The results of this study indicate a significant correlation between the level of knowledge (r=-0,332; p < 0,05) and level of drug adherence (r=-0,644; p < 0,05) to the level of systemic lupus erythematosus flaresConclusion : Based on the results, there is a correlation between knowledge and drug adherence to the level of systemic lupus erythematosus flares. The recommendation given is an integrated approach between patients and health care providers to improve patients understanding of systemic lupus erythematosus flares. Beside of that, specific attention should be paid to integrate the service provision system into the collaborative approach of the patients and his/her family in order to promote the level of drug adherence. ","PeriodicalId":224385,"journal":{"name":"Jurnal Epidemiologi Kesehatan Komunitas","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132454330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}