Juntendo Medical Journal最新文献_第3页

Status of Normal Weight Obesity Among Japanese Women Under 40 Years Old 日本40岁以下女性正常体重肥胖状况

Juntendo Medical Journal Pub Date : 2020-04-22 DOI: 10.14789/jmj.2020.66.jmj19-oa23

Y. Nakanishi, Shinobu Sakurai, Y. Kawata, Yoshio Suzuki, Mayu Takaya, Shimpei Fujita, K. Sakuraba, Masataka Hirosawa, Takao Okada

{"title":"Status of Normal Weight Obesity Among Japanese Women Under 40 Years Old","authors":"Y. Nakanishi, Shinobu Sakurai, Y. Kawata, Yoshio Suzuki, Mayu Takaya, Shimpei Fujita, K. Sakuraba, Masataka Hirosawa, Takao Okada","doi":"10.14789/jmj.2020.66.jmj19-oa23","DOIUrl":"https://doi.org/10.14789/jmj.2020.66.jmj19-oa23","url":null,"abstract":"Objective : This study examined the prevalence of and factors affecting normal weight obesity (NWO) among women aged under 40 years old. NWO was having a normal BMI but a high body-fat percentage (BFP). Materials and Methods : We recruited 399 participants aged 1839 during a health checkup and surveyed them about lifestyle patterns, height, weight, body composition, and girth and visceral fat area. Participants were divided into three. Those with a BMI of <25 and a BFP of <30 were classified as non-obese, a BMI of <25 and a BFP of ≥ 30 as NWO, a BMI of ≥ 25 and a BFP of ≥ 30 as obese. The analysis was conducted on NWO (97) and non-obese (262) groups. Results : NWO prevalence ranged from 20% to 30% across the three age groups. NWO participants had lower values for segmental lean body mass, particularly in lower limb, and higher values for abdominal girth and visceral fat area. Among participants aged 3039, those with NWO had higher values for triglycerides and LDL cholesterol and lower values for HDL cholesterol. Regarding lifestyle factors, among those aged 3039, NWO was associated with past weight fluctuation, respectively. In the latter age group, a gain of more than 10 kg since the age of 20 was associated with a 13-fold increase in the odds for NWO. Conclusions : Results suggest that for women under 40 years, detecting NWO early and guidance on effective lifestyle and exercise are necessary.","PeriodicalId":223994,"journal":{"name":"Juntendo Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116146053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Effects of Coordination Exercises on Social Functioning: Evidence from fMRI and Social-ability Measures 协调训练对社会功能的影响:来自功能磁共振成像和社会能力测量的证据

Juntendo Medical Journal Pub Date : 2020-02-18 DOI: 10.14789/jmj.2020.66.jmj19-oa21

M. M. Sudo, A. Mochizuki, E. Kirino, K. Itoh

{"title":"Effects of Coordination Exercises on Social Functioning: Evidence from fMRI and Social-ability Measures","authors":"M. M. Sudo, A. Mochizuki, E. Kirino, K. Itoh","doi":"10.14789/jmj.2020.66.jmj19-oa21","DOIUrl":"https://doi.org/10.14789/jmj.2020.66.jmj19-oa21","url":null,"abstract":"Objective : Research has demonstrated the positive effects of physical activities on social cognition. The purpose of the present study was to find out whether coordination exercises have a beneficial effect on enhancing social functioning. We investigated the activation of the brain areas associated with doing one-person coordination exercises, as compared to doing two-person coordination exercises. We were interested in testing the hypothesis that two-person coordination exercises activate those brain areas underlying communication abilities, empathy in“theory of mind”(ToM), and working memory in social cognition. Materials : Thirty-four Japanese college students served as subjects. Methods : In the MRI system, the subjects carried out block-designed cognitive tasks containing affective visual stimuli (pleasant, unpleasant, and neutral stimuli). Then they got out of the MRI system and performed both one-person coordination and two-person coordination exercises. Just after the exercises, they were retested using the same types of the affective stimuli in the MRI system. We examined social abilities in terms of empathizing and memory span. Results : The present study provided evidence that coordination exercises activate language, working memory, and theory of mind functions. One of the fMRI results to be noted is that the right, but not the left, anterior cingulate correlated with the working memory function. Conclusions : We provided evidence for the effect of performing coordination exercises on the activation of the left frontal gyrus related to social functioning. We could also provide support for the hypothesis that two-person coordination exercises activate both the working memory function and the ToM function.","PeriodicalId":223994,"journal":{"name":"Juntendo Medical Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126768461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methotrexate and Oral Antirheumatic Drugs 甲氨蝶呤和口服抗风湿药

Juntendo Medical Journal Pub Date : 2020-02-01 DOI: 10.14789/jmj.2020.66.jmj19-r05

Kwangseok Yang, M. Matsushita, N. Tamura

引用次数: 0

ACTN3 R577X Genotype Is Associated with ACTN3 Protein Expression Levels and Myosin Heavy Chain Composition in Japanese College-Level Male Sprinters 日本大学水平男性短跑运动员ACTN3 R577X基因型与ACTN3蛋白表达水平和肌球蛋白重链组成相关

Juntendo Medical Journal Pub Date : 2019-09-25 DOI: 10.14789/jmj.2019.65.jmj19-oa08

Tomohiro Nakamura, R. Kakigi, Noriko Ichinoseki‐Sekine, Takamasa Tsuzuki, Hiroyuki Kobayashi, K. Sakuma, H. Naito

引用次数: 0

The Intravenous Diazepam Interview for Motor Paralysis Cases Influenced by Psychiatric Disorder 精神障碍所致运动麻痹患者静脉注射安定的疗效观察

Juntendo Medical Journal Pub Date : 2019-04-27 DOI: 10.14789/JMJ.2019.65.JMJ18-CR04

A. Nishizawa, Kiyoshi Ito, Tomoki Nakano

{"title":"The Intravenous Diazepam Interview for Motor Paralysis Cases Influenced by Psychiatric Disorder","authors":"A. Nishizawa, Kiyoshi Ito, Tomoki Nakano","doi":"10.14789/JMJ.2019.65.JMJ18-CR04","DOIUrl":"https://doi.org/10.14789/JMJ.2019.65.JMJ18-CR04","url":null,"abstract":"Background: Motor rehabilitation may be rarely disrupted by psychiatric disorders including conversion disorder and catatonia. The amobarbital or diazepam interview can be implemented for both the diagnosis and treatment of these disorders. We report two typical cases presenting with motor paralysis influenced by psychiatric disorder that were effectively diagnosed and treated using the diazepam interview in convalescent rehabilitation. Cases: Case 1 was a 32-year-old man. He experienced severe paralysis and sensory disturbance of the right arm and leg while at work, and then received conservative treatment for stroke. One month later, after the diazepam interview, he rapidly recovered almost entirely from his paralysis and sensory disturbance, which led to a diagnosis of conversion disorder. Case 2 was a 42-yearold man. After becoming an alcoholic, both legs had gradually become severely paralyzed. Two months later, he was uncommunicative and refused rehabilitation and nursing care. He briefly became communicative during the diazepam interview, and was diagnosed with delusional depressed state with stupor. Six months later, both legs remained spastic and paralyzed. Although he was subacute with combined degeneration of the spinal cord, taking conversion disorder overlap into consideration, we conducted the diazepam interview again; he immediately recovered slight voluntary extension and flexion of both legs. Conclusions: We describe two motor disturbance cases influenced by psychiatric disorders. For both patients, the diazepam interview was shown to be an effective method for the diagnosis and treatment of a psychiatric disorder. Our findings suggest that the diazepam interview could be appropriate for use in the rehabilitation area when conducted correctly.","PeriodicalId":223994,"journal":{"name":"Juntendo Medical Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123876758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Validation of PCR-Based Testing for Surveillance of Drug Resistant Acinetobacter baumannii (ISAba1/blaOXA-51-Like) in a Pediatric Ward 儿科病房耐药鲍曼不动杆菌(ISAba1/blaOXA-51-Like)监测的pcr检测验证

Juntendo Medical Journal Pub Date : 2018-12-06 DOI: 10.14789/JMJ.2018.64.JMJ18-OA07

Naruaki Imoto, K. Obinata, T. Nakazawa, S. Sasaki

{"title":"Validation of PCR-Based Testing for Surveillance of Drug Resistant Acinetobacter baumannii (ISAba1/blaOXA-51-Like) in a Pediatric Ward","authors":"Naruaki Imoto, K. Obinata, T. Nakazawa, S. Sasaki","doi":"10.14789/JMJ.2018.64.JMJ18-OA07","DOIUrl":"https://doi.org/10.14789/JMJ.2018.64.JMJ18-OA07","url":null,"abstract":"Objective : This study was performed to validate PCR-based testing for surveillance of Acinetobacter baumannii ( A. baumannii ) in a pediatric ward in response to an outbreak of drug resistant A. baumannii (IS Aba1 / bla OXA-51-like) in our tertiary care hospital. Materials : All children who were admitted to the pediatric ward were included in this study. The surveillance study was carried out from March 2012 to December 2013. Methods : After collecting samples from all children in our pediatric ward, PCR analyses were conducted. IS Aba1 / bla OXA-51-like gene-positive patients were isolated from other patients and strict standard precautionary procedures for infection control were put into practice. Results : During the survey period, a total of 1,038 children underwent surveillance on admission. Of the 16 cases of Acinetobacter baumannii colonization identified during surveillance, 6 were positive for the IS Aba1 / bla OXA-51-like gene, and all IS Aba1 / bla OXA-51-like gene-positive patients received mechanical ventilation. No new IS Aba1 / bla OXA-51-like gene-positive cases were identified during the last six months of surveillance. However, among the 10 IS Aba1 / bla OXA-51-like gene-negative A. baumannii cases, 3 were neonates transferred from the same gynecological hospital. Conclusion : PCR-based testing was effective for stopping transmission of an A. baumannii outbreak in a pediatric ward. This event emphasized the importance of surveillance and interfacility communication among hospitals for prevention of infection outbreaks.","PeriodicalId":223994,"journal":{"name":"Juntendo Medical Journal","volume":"271 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133473651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Physical Activity in Patients with Chronic Obstructive Pulmonary Disease Using an Accelerometer with Tapestry-Style Display Capability 使用具有挂毯式显示能力的加速度计评估慢性阻塞性肺疾病患者的身体活动

Juntendo Medical Journal Pub Date : 2018-09-07 DOI: 10.14789/JMJ.2018.64.JMJ17-OA16

Miharu Kato, M. Sekiya, Yohei Suzuki, Tadashi Sato, Masako Ichikawa, Y. Kodama, K. Seyama, Eri Aikawa-Hirasawa, Kazuhisa Takahashi

引用次数: 0

Characteristics of Bone Metabolism in Middle-Aged and Older Mountaineers 中老年登山运动员骨代谢的特点

Juntendo Medical Journal Pub Date : 2018-08-17 DOI: 10.14789/JMJ.2018.64.JMJ17-OA11

S. Nakamaru, K. Sakuraba, Shimpei Fujita

引用次数: 1

Primary Care Physicians' Use of Antipsychotics for the Treatment of Behavioural and Psychological Symptoms of Dementia in Japan 日本初级保健医生使用抗精神病药物治疗痴呆的行为和心理症状

Juntendo Medical Journal Pub Date : 2018-08-08 DOI: 10.14789/JMJ.2018.64.JMJ18-OA01

Toshiki Takayama, N. Shibata, T. Ohnuma, Koichi Miyakawa, Yoshihide Takeshita, Ayako Suzuki, Moto Nishiguchi, H. Arai

{"title":"Primary Care Physicians' Use of Antipsychotics for the Treatment of Behavioural and Psychological Symptoms of Dementia in Japan","authors":"Toshiki Takayama, N. Shibata, T. Ohnuma, Koichi Miyakawa, Yoshihide Takeshita, Ayako Suzuki, Moto Nishiguchi, H. Arai","doi":"10.14789/JMJ.2018.64.JMJ18-OA01","DOIUrl":"https://doi.org/10.14789/JMJ.2018.64.JMJ18-OA01","url":null,"abstract":"Objective: We aimed to investigate how primary care physicians (PCPs) in Japan use antipsychotics for treating the behavioural and psychological symptoms of dementia (BPSD). Materials and Methods: A nationwide cross-sectional online survey was conducted of PCPs who annually treated patients aged over 65 years with dementia. Responses from 509 PCPs were analysed by binominal logistic regression analysis. Results: Approximately one-third of the PCPs had treated excitatory BPSD (delusion, hallucination, agitation and violence), with half of them prescribing antipsychotics for this. Some PCPs still prescribed antipsychotics for non-excitatory BPSD, such as wandering. More than half of the PCPs had opportunities to learn about the appropriate use of antipsychotics and understood the increased mortality risk in elderly people with dementia. Referring to the Japanese Governmentʼs BPSD guideline for PCPs was negatively associated with antipsychotic dosage (odds ratio=0.491, 95% confidence intervals 0.32-0.75, p-value=0.001) and positively associated with a greater awareness of increased mortality with antipsychotics (odds ratio = 2.149, 95% confidence intervals 1.41-3.27, p-value=0.0004). Conclusion: PCPs continue to prescribe antipsychotics for excitatory BPSD in clinical practice despite official information about mortality risks. Educational material about the appropriate use of the antipsychotics should include specific mention of the risks of using antipsychotics for dementia.","PeriodicalId":223994,"journal":{"name":"Juntendo Medical Journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121923980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathophysiology of Nonalcoholic Steatohepatitis 非酒精性脂肪性肝炎的病理生理学

Juntendo Medical Journal Pub Date : 2017-08-01 DOI: 10.14789/JMJ.63.230

Sumio Watanabe

引用次数: 283