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The East and Central African Journal of Pharmaceutical Sciences最新文献

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Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst 海参戊二酰亚胺生物碱对卤虾的致死性研究
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-09-06 DOI: 10.4314/ECAJPS.V8I1.9716
M. Kapingu, Z. Mbwambo, M. Moshi, Jj Magadula
{"title":"Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst","authors":"M. Kapingu, Z. Mbwambo, M. Moshi, Jj Magadula","doi":"10.4314/ECAJPS.V8I1.9716","DOIUrl":"https://doi.org/10.4314/ECAJPS.V8I1.9716","url":null,"abstract":"No Abstract. The East and Central African Journal of Pharmaceutical Sciences Vol. 8(1) 2005: 3-5","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"121 1","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"2006-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85971749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Anthelminthic activity of Withania somnifera . L. Dunal water extract in sheep 牡丹的虫栖活性。绵羊杜纳尔水提取物
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-09-06 DOI: 10.4314/ECAJPS.V8I1.9717
J. O. Miaron, Pg Wahome, Im Mapenay
{"title":"Anthelminthic activity of Withania somnifera . L. Dunal water extract in sheep","authors":"J. O. Miaron, Pg Wahome, Im Mapenay","doi":"10.4314/ECAJPS.V8I1.9717","DOIUrl":"https://doi.org/10.4314/ECAJPS.V8I1.9717","url":null,"abstract":"No Abstract. The East and Central African Journal of Pharmaceutical Sciences Vol 8(1) 2005: 6-9","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"1 1","pages":"6-9"},"PeriodicalIF":0.0,"publicationDate":"2006-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77237530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Human poisoning with plants in Kenya 肯尼亚人因植物中毒
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-09-06 DOI: 10.4314/ECAJPS.V8I1.9718
C. Maitai, N. Mungai
{"title":"Human poisoning with plants in Kenya","authors":"C. Maitai, N. Mungai","doi":"10.4314/ECAJPS.V8I1.9718","DOIUrl":"https://doi.org/10.4314/ECAJPS.V8I1.9718","url":null,"abstract":"No Abstract. The East and Central African Journal of Pharmaceutical Sciences Vol. 8(1) 2005:10-13","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"10 1","pages":"10-13"},"PeriodicalIF":0.0,"publicationDate":"2006-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88461856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Formulation and evaluation of tenoxicam gels for tropical use 热带用替诺昔康凝胶的配方及评价
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-09-06 DOI: 10.4314/ECAJPS.V8I1.9719
S. M. Maru, F. Manvi
{"title":"Formulation and evaluation of tenoxicam gels for tropical use","authors":"S. M. Maru, F. Manvi","doi":"10.4314/ECAJPS.V8I1.9719","DOIUrl":"https://doi.org/10.4314/ECAJPS.V8I1.9719","url":null,"abstract":"No Abstract. The East and Central African Journal of Pharmaceutical Sciences Vol. 8(1) 2005: 14-19","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"32 1","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2006-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91244571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adherence to antiretroviral drugs in North-Central zone of Nigeria 尼日利亚中北部地区抗逆转录病毒药物的依从性
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-07-21 DOI: 10.4314/ECAJPS.V7I3.9713
M. Mohammed, R. Sarki
{"title":"Adherence to antiretroviral drugs in North-Central zone of Nigeria","authors":"M. Mohammed, R. Sarki","doi":"10.4314/ECAJPS.V7I3.9713","DOIUrl":"https://doi.org/10.4314/ECAJPS.V7I3.9713","url":null,"abstract":"A cross-sectional study of 110 patients attending State House Clinic, Abuja were assessed for compliance in time and dose of anti-retroviral drugs for one month. One hundred and five of the patients complied to taking the drugs (taking complience >95%) and compliance to the dosage was also good (98.1%). However, the mean timing compliance was not good (73.1%). Forgetfulness (7.0%) and travelling out of town (4.3%) were the commonest reasons for missing a dose. Forgetfulness (20%), non-availability of food (25.5%) and stigmatization of carrying drugs around (3.6%) were the commonest reasons for altering the dosing time. It was concluded that the timing compliance was low and that may affect the success of the program. Patients should be encouraged to take the right dose at the right time. Keywords : adherence, antiretroviral drugs, taking compliance, timing compliance, dosing compliance The East and Central African Journal of Pharmaceutical Sciences Vol. 7(3) 2004: 52-55","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"37 1","pages":"52-55"},"PeriodicalIF":0.0,"publicationDate":"2006-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82239805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Formulation of a topical sun protection cream for people with albinism 针对白化病患者的局部防晒霜配方
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-07-21 DOI: 10.4314/ECAJPS.V7I3.9715
Moipone L Moloisane, W. Liebenberg, A. P. Lötter, M. M. Villiers
{"title":"Formulation of a topical sun protection cream for people with albinism","authors":"Moipone L Moloisane, W. Liebenberg, A. P. Lötter, M. M. Villiers","doi":"10.4314/ECAJPS.V7I3.9715","DOIUrl":"https://doi.org/10.4314/ECAJPS.V7I3.9715","url":null,"abstract":"The aim of this investigation was to design and develop a sun protection product for people with albinism that is affordable, applicable to their specific skin condition, and provide them with the maximum sun protection possible. To achieve the required Sun Protection Factor value of > 20, simple creams were combined with very fine inorganic oxides (zinc oxide and titanium dioxide) and organic sunscreen filters (2-ethylhexyl cinnamate and octyl methoxycinnamate). These combinations also ensured high UV A /UV B protection ratios. The physical stability and change in Sun Protection Factor were for products stored for 8 weeks at 25°C (60% RH) and 45°C (75% RH) were also determined. Hypoallergenic and physically stable product(s) were formulated with SPF values between 20 to 30 and UV A /UV B ratios above 0.8 by combining simple cream formulations with fine particle inorganic oxides and organic UV protection agents. This approach offered an opportunity to formulate broad-spectrum sunscreen products that met the needs of albinos. Keywords : sun protection cream, sun protection factor, albinism The East and Central African Journal of Pharmaceutical Sciences Vol. 7(3) 2006: 60-64","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"21 1","pages":"60-64"},"PeriodicalIF":0.0,"publicationDate":"2006-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72948799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct compression properties of microcrystalline cellulose and its silicified product 微晶纤维素及其硅化产物的直接压缩性能
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-07-21 DOI: 10.4314/ECAJPS.V7I3.9714
J. Alfa, Michael A. Odeniyi, K. T. Jaiyeoba
{"title":"Direct compression properties of microcrystalline cellulose and its silicified product","authors":"J. Alfa, Michael A. Odeniyi, K. T. Jaiyeoba","doi":"10.4314/ECAJPS.V7I3.9714","DOIUrl":"https://doi.org/10.4314/ECAJPS.V7I3.9714","url":null,"abstract":"The influence of silicified microcrystalline cellulose (SMCC) on the flow, compaction and tableting properties of metronidazole powder was investigated. The study compared medium grades of both SMCC and standard microcrystalline cellulose (MCC) as direct compressible excipients. The bulk densities, Hausner quotient (H f ), compressibility index (CI) and angle of repose of the formulations were evaluated. Compacts of the metronidazole containing different concentrations of SMCC or MCC (10-30% w/w) were made at compression forces of 20 to 30 KN and evaluated for their physical characteristics. The flow behaviour of the drug was improved in the presence of SMCC. Formulations containing 25% w/w SMCC had lower CI and H f values than those made with 30% w/w MCC. The crushing strength of the compacts increased with concentration of the excipients at all the compression forces used. At similar concentrations of SMCC and MCC, compacts of the formulations containing SMCC exhibited higher crushing strengths. SMCC shows great promise as a filler-binder-disintegrant in direct compression of oral tablet formulations from both mechanical and economic viewpoints. Keywords : metronidazole, tablets, direct compression, Silicified Microcrystalline cellulose, microcrystalline cellulose The East and Central African Journal of Pharmaceutical Sciences Vol. 7(3) 2004: 56-59","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"6 1","pages":"56-59"},"PeriodicalIF":0.0,"publicationDate":"2006-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82490957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
An approach to effective disinfection of salon items [clippers, combs and scissors] 沙龙用品(剪刀、梳子、剪刀)的有效消毒方法
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-07-21 DOI: 10.4314/ECAJPS.V7I3.9712
O. Olonitola, P. Olurinola, J. Ehinmidu
{"title":"An approach to effective disinfection of salon items [clippers, combs and scissors]","authors":"O. Olonitola, P. Olurinola, J. Ehinmidu","doi":"10.4314/ECAJPS.V7I3.9712","DOIUrl":"https://doi.org/10.4314/ECAJPS.V7I3.9712","url":null,"abstract":"Antibacterial susceptibility patterns of some bacteria isolated from selected barbing salons in parts of Northern Nigeria was studied for the purpose of developing a disinfectant system suitable for use in salons. The K-values for selected cells ranged from 0.0072 to 0.0399 (benzalkonium chloride), and from 0.0062 to 0.1338 (propylene glycol) as against a range of 0.0147 to 0.1343 when the two chemicals were combined. The observed D-value range of 64.5 to 99 (benzalkonium chloride), 31.5 to 105 (Propylene glycol) and 21 to 24 (admixture of the two chemicals) were exploited in the development of “SALONSEFE” – a salon disinfectant that was able to eliminate 105 cfu/ ml (of the most resistant bacterial isolated in these studies) completely in 60 seconds. Keywords : salonsafe, antibacterial, disinfectant, salon, K-value, D-value The East and Central African Journal of Pharmaceutical Sciences Vol. 7(3) 2004: 47-51","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"20 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2006-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84760936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Evidence of male attractants for fruit flies in the leaf extract of Schinus molle 凤尾蛇叶提取物中雄性引诱剂对果蝇的影响
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-05-17 DOI: 10.4314/ECAJPS.V7I2.9709
N. Gikonyo, S. Lux
{"title":"Evidence of male attractants for fruit flies in the leaf extract of Schinus molle","authors":"N. Gikonyo, S. Lux","doi":"10.4314/ECAJPS.V7I2.9709","DOIUrl":"https://doi.org/10.4314/ECAJPS.V7I2.9709","url":null,"abstract":"Attractiveness of odor from leaves of pepper tree ( Schinus molle ) to male Ceratitis rosa and C. capitata was evaluated in a wind-tunnel. Odor from the leaves was as attractive to male C. rosa as Trimedlure and more attractive to C. capitata males. Responses of both male and female C. cosyra, C. rosa and C. capitata when presented with an extract from S. molle leaves were also evaluated. The flies were highly activated and only males were attracted and landed on the treated dispenser. Onset of activation was more rapid for C. rosa and C. capitata than for C. cosyra . Similarly, large numbers of male C. capitata and C. rosa landed on treated dispenser than C. cosyra . Analysis of the S. molle extract by gas chromatography and gas chromatography–mass spectrometry revealed several monoterpenes and sesquiterpenes. Some of the terpenoids or their blend may constitute a male attractant (parapheromone) for C. capitata, C. rosa and possibly other fruit flies attracted to Trimedlure. Keywords : fruit fly, Ceratitis capitata, C. cosyra, C. rosa , parapheromone, Schinus molle , pepper tree East and Central African Journal of Pharmaceutical Sciences Vol. 7 2004: 27-33","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"72 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2006-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82652659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation of synthetic spermaceti wax as a potential oral sustained release drug delivery system 合成脑蜡作为一种潜在的口服缓释给药体系的研究
The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2006-05-17 DOI: 10.4314/ECAJPS.V7I2.9708
R. Chigwanda, A. Kuudzadombo
{"title":"Investigation of synthetic spermaceti wax as a potential oral sustained release drug delivery system","authors":"R. Chigwanda, A. Kuudzadombo","doi":"10.4314/ECAJPS.V7I2.9708","DOIUrl":"https://doi.org/10.4314/ECAJPS.V7I2.9708","url":null,"abstract":"The present study was aimed at investigating drug release from spermaceti wax matrices. Materials such as ethylcellulose and methylcellulose were incorporated into the spermaceti wax matrices and release was evaluated. Spermaceti wax can form matrices that release drug in a sustained release fashion. Higuchi or first order release kinetics were found to explain drug release from spermaceti wax, spermaceti wax-ethylcellulose and spermaceti wax-methylcellulose matrices. However, ethylcellulose and methylcellulose enhanced release rate from spermaceti wax matrices. Spermaceti wax matrices can be used to provide drug delivery systems with prolonged action. Release rate from such systems can be regulated by incorporation of materials such as ethylcellulose and methylcellulose. Keywords : carnauba wax, sustained release, particle size, and kinetics East and Central African Journal of Pharmaceutical Sciences Vol. 7 2004: 24-26","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"20 1","pages":"24-26"},"PeriodicalIF":0.0,"publicationDate":"2006-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84763851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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