Tanta Medical Journal最新文献

Evaluation of mitochondria dysfunction in streptozotocin-induced diabetic nephropathy 链脲佐菌素所致糖尿病肾病中线粒体功能障碍的评价

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_56_22

Nada Khedr, Rasha Gaber, Noha Shafik, Nadia El-Ashwah

{"title":"Evaluation of mitochondria dysfunction in streptozotocin-induced diabetic nephropathy","authors":"Nada Khedr, Rasha Gaber, Noha Shafik, Nadia El-Ashwah","doi":"10.4103/tmj.tmj_56_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_56_22","url":null,"abstract":"Background Oxidative stress, mitochondrial stress, and autophagy are profoundly implicated in β-cell dysfunction and in the pathophysiology of type 2 diabetes mellitus. Aim The study was designed to explore the relationship between mitochondrial dysfunction and oxidative stress on one hand and their correlation to severity of diabetic nephropathy on the other hand. Material and methods This study was conducted on 40 male albino rats approximately weighing 100–150 g, which were randomly divided into two equal groups (20 rats each). Results The results revealed an increase in the body weight and in the plasma levels of glucose, urea, and creatinine in the diabetic nephropathy group I compared with the control group II. Moreover, there was a significant increase in the level of dynamin-related protein 1 and in 24-h urinary microalbumin excretion in the diabetic nephropathy group compared with the control group. On the contrary, a significant decrease in the levels of optic protein atrophy 1 and reduced glutathione levels was found in the diabetic nephropathy group compared with the control group. Conclusion The study has proved that mitochondrial dysfunction is closely related to diabetic nephropathy that is expressed in decreased optic protein atrophy 1 level and increased dynamin-related protein 1 level on one side, and also related to hyperglycemic oxidative stress evidenced by decreased glutathione level on the other side, and their correlation to the severity of diabetic nephropathy.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124976171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum serotonin level as a predictor of presence of gastroesophageal varices in patients with liver cirrhosis 血清血清素水平作为肝硬化患者胃食管静脉曲张存在的预测因子

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_1_22

Tasnim Adam, Mahmoud Abdelsamea, S. Abd-Elsalam, Hesham Elserougy, Elsaid Wasfy

{"title":"Serum serotonin level as a predictor of presence of gastroesophageal varices in patients with liver cirrhosis","authors":"Tasnim Adam, Mahmoud Abdelsamea, S. Abd-Elsalam, Hesham Elserougy, Elsaid Wasfy","doi":"10.4103/tmj.tmj_1_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_1_22","url":null,"abstract":"Background Portal hypertension is one of the most important complications of liver cirrhosis, leading to the development of esophageal varices (OV). Variceal bleeding carries high morbidity and mortality. The frequency of varices in patients with cirrhosis is unfixed, extended from 24 to 80%; therefore, endoscopic examination of all cirrhotic patients would lead to unnecessary additional burdens to endoscopic units. Aim The aim of the study was to evaluate the serum serotonin level as a noninvasive predictor of presence of gastroesophageal varices in patients with liver cirrhosis. Patients and methods The study was performed on 60 cirrhotic patients recruited from the endoscopy unit of Tropical Medicine and Infectious Diseases Department in Tanta University Hospitals. In addition, 20 physically fit participants served as a control group within the period between April 2020 and April 2021. Results Serum serotonin is significantly increased in cirrhotic patients with varices. Serum serotonin correlated well with severity of liver insult in patients with cirrhosis assessed by Child, Model for End Stage Liver Disease, fibrosis-4, and aspartate aminotransferase/platelet ratio index scores as well as OV grade. Conclusion Serum serotonin had a good power of prediction for development of OV.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132083481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-guided injection of platelet-rich plasma in partial anterior cruciate ligament injury 超声引导下富血小板血浆在部分前交叉韧带损伤中的应用

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_46_19

Zeinab Selima, H. Khallaf, Hanan El-Saadany, F. Rehan

{"title":"Ultrasound-guided injection of platelet-rich plasma in partial anterior cruciate ligament injury","authors":"Zeinab Selima, H. Khallaf, Hanan El-Saadany, F. Rehan","doi":"10.4103/tmj.tmj_46_19","DOIUrl":"https://doi.org/10.4103/tmj.tmj_46_19","url":null,"abstract":"Background The most common injuries in athletes are anterior cruciate ligament (ACL) tears and are associated with a nontouch pivoting harm mechanism in a deceleration maneuver. Platelet-rich plasma (PRP) therapy is a low-cost, simple, and minimally invasive therapy that can provide a concentration of natural blood growth factors. The use of PRP has been validated to be beneficial in enhancing ligament healing, mainly ACL in vitro, in animals, and in humans. Aim The goal of the work was to study the effect of ultrasound (US)-guided injection of PRP in the treatment of partial ACL injury. Patients and methods This study included 30 patients with partial ACL injuries selected from the outpatient medical institution of Physical Medicine, Rheumatology and Rehabilitation Department, Tanta University Hospitals. All patients underwent detailed history taking, clinical examination, and MRI examination. Visual analog score, Lachman test, Tegner Activity Scale, and knee outcome survey were performed before and after injection. Patients were injected with 5 ml of PRP two times 1 week apart under US guidance. Results There were significant differences between visual analog score before injection and 1 week after second injection and after 6 months of follow-up. There was insignificant improvement of the Lachman test 6 months after injection. There were significant improvements of Tegner Activity Scale, knee outcome survey of Activities of Daily Living Scale, and Cincinnati Sports Activity Scale after injection. Conclusion Although US-guided PRP injection failed to show any structural improvement in partial ACL injury, it showed improvement of pain and functional activity.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132250354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac dysrhythmia in drug-resistant epileptic children 耐药癫痫患儿心律失常

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_63_22

Mohamed ElNawasany, Mohamed Basiouny, M. Khalfallah, Tarek ElGammal

{"title":"Cardiac dysrhythmia in drug-resistant epileptic children","authors":"Mohamed ElNawasany, Mohamed Basiouny, M. Khalfallah, Tarek ElGammal","doi":"10.4103/tmj.tmj_63_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_63_22","url":null,"abstract":"Background Drug-resistant epilepsy is one of the most common neurological conditions associated with high mortality and morbidity rates. Aim To assess heart rate variability among drug-resistant epileptic children. Patients and methods This observational cross-sectional case–control study included 60 epileptic children. Cases were assigned into two equal groups: group 1 (drug-resistant group) included children presented with drug-resistant epilepsy and group 2 (control group) included cases with controlled primary epilepsy who achieved sustained seizure freedom for at least 6 months on one antiepileptic drug, matched with the patient group regarding age and sex. All patients were subjected to history taking and clinical and radiological investigations including computed tomography (CT) and/or MRI and electroencephalogram (EEG) monitoring. ECG monitoring was using Holter ECG. Results MRI, EEG, and ECG abnormalities are significantly more common in drug-resistant epilepsy. Interictal tachycardia was the most prevalent abnormality among group I (93.3%). ECG structure was abnormal in 33.3% in group I, in the form of prolonged QTc interval, ST segment abnormalities, P wave dispersion, and T wave alternans. Tachycardia associated with prolonged QTc interval was present in patients with focal or temporal EEG abnormalities, and patients with multifocal EEG abnormalities. Conclusion ECG monitoring is important in drug-resistant epileptic children to detect any autonomic changes occurring in the heart either ictally or interictally. Heart rate is significantly higher and RR interval is significantly shorter ictally than interictally. Careful monitoring of these changes may help in predicting the risk of sudden unexpected death.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116138357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endostatin level in coronavirus patients: a prospective study 冠状病毒患者内皮抑素水平:一项前瞻性研究

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_62_22

Ahmed Zahra, Mohamed Abd-Elall, M. Hantera, A. Sakran, Mohamed Zahra

{"title":"Endostatin level in coronavirus patients: a prospective study","authors":"Ahmed Zahra, Mohamed Abd-Elall, M. Hantera, A. Sakran, Mohamed Zahra","doi":"10.4103/tmj.tmj_62_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_62_22","url":null,"abstract":"Background Endostatin is a protein linked to the C-terminal of collagen in the basement membrane of endothelial cells. It functions as an antiangiogenic protein. It inhibits endothelial proliferation, migration, and tube formation. Studies have observed that it downregulates endothelial-signaling pathways of proangiogenic activity as well as upregulates the angiogenic gene. Aim This work was designated to explore the levels of endostatin in coronavirus disease 2019, trying to investigate its role as a prognostic marker. Patients and methods Patients with positive PCR for SARS-CoV-2 were divided into two groups (survivors and nonsurvivors). Computed tomography chest was for each patient. The nonsurvivor group comprised 19 patients and the survivor group had 31 patients. In addition, 50 normal volunteers participated in this study and served as a control group. Serum endostatin was measured by ELISA and was compared with other measured laboratory parameters. Results Endostatin was statically increased in nonsurvivors than both survivors and normal volunteers (P1=0.007, P2=<0.001). However, this significant increase was still observed in survivors on comparing with normal individuals. There was a correlation between endostatin and different parameters in coronavirus disease 2019 patients. Conclusion The high level of endostatin in this prospective study and its correlation with laboratory makers and clinical manifestations leads us to consider it as a valuable prognostic factor. Moreover, it can predict mortality and severity of patients. It was important to conduct a study on large scale to confirm this value.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114672189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The potential role of omega-3 on the effect of the energy drinks on testis of adult male albino rats: a histological and immunohistochemical study omega-3对能量饮料对成年雄性白化大鼠睾丸影响的潜在作用:一项组织学和免疫组织化学研究

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_27_22

Rana Maksoud Mangoud, Safwat El-Deeb, Amal Mahdy, Hend El-Hanafy

{"title":"The potential role of omega-3 on the effect of the energy drinks on testis of adult male albino rats: a histological and immunohistochemical study","authors":"Rana Maksoud Mangoud, Safwat El-Deeb, Amal Mahdy, Hend El-Hanafy","doi":"10.4103/tmj.tmj_27_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_27_22","url":null,"abstract":"Background Consumption of energy drinks rich in caffeine has increased between individuals. Health problems related to caffeine such as reproductive diseases have occurred. Aim The objective of this work was to study the potential role of omega-3 on the effect of energy drinks on the testis of adult male albino rats. Material and methods A total of 40 adult male albino rats were used in this study. Rats were divided into four main groups: control group (I) included 10 rats that received no treatment for the same periods as the experimental animals; omega-3 group (II) included 10 rats that received 300 mg/kg body weight of omega-3 orally using a gastric tube once daily for 3 months; energy drink group (III) included 10 rats that received 1.07 ml/100 g body weight of energy drink orally using a gastric tube once daily for 3 months; and energy drink and omega-3 group (IV) included 10 rats that concomitantly received both energy drink and omega-3 at the same dose, route, and duration as groups II and III. Testicular specimens were subjected to histological and immunohistochemical examinations. The data were analyzed statistically. Results Group III showed disturbed normal histological architecture of the testicular structure, but group IV omega-3 resulted in preservation of the normal histological architecture. Moreover, the cyclooxygenase 2 immune stain and the statistical analysis confirm these results. Conclusion There is a correlation between omega-3 and reduction of the testicular damage induced by energy drinks in adult male albino rats. Omega-3 leads to protection of the testis.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133558546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The possible association between blood level of free cholesterol and the severity of steatosis in patients with nonalcoholic fatty liver disease 非酒精性脂肪肝患者血液游离胆固醇水平与脂肪变性严重程度之间的可能关联

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_23_22

A. Elsawy, Hossam A. Hodeib, A. Selim, Mohamed E Sarhan, Ahmed A. Elhadidy, Heba Sameir, Amal Selim, Mohamed Tawfik

{"title":"The possible association between blood level of free cholesterol and the severity of steatosis in patients with nonalcoholic fatty liver disease","authors":"A. Elsawy, Hossam A. Hodeib, A. Selim, Mohamed E Sarhan, Ahmed A. Elhadidy, Heba Sameir, Amal Selim, Mohamed Tawfik","doi":"10.4103/tmj.tmj_23_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_23_22","url":null,"abstract":"Background The global rising prevalence of nonalcoholic fatty liver disease (NAFLD) highlights the need to understand the risk factors related to its pathogenesis and its related complications. NAFLD is mediated by lipotoxicity that results from an imbalance in hepatic lipid metabolism. Emerging evidence suggests that lipotoxicity mediated by hepatic free cholesterol (FC) overload may result in steatohepatitis. Lipotoxicity is not only associated with the pathogenesis of NAFLD, but also related to increased risk of atherosclerosis and cardiovascular complications, the main leading causes of mortality in NAFLD. Aim The study tried to clarify the possible association between serum levels of FC and the severity of hepatic steatosis in NAFLD. Patients and methods This cross-sectional study included 120 participants, who proved to have different stages of hepatic steatosis using elastography with controlled attenuation parameter (CAP). The correlations between different lipid parameters as well as serum FC levels and CAP values of hepatic steatosis for all participants were assessed using multivariate linear regression analysis. Results The most independent significant lipid parameters associated with CAP values were FC, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol (P<0.001 for all). Moreover, the discriminately performance of those parameters as risk factors for steatosis using receiver operating characteristics showed an area under the curve of 0.991, 0.957, and 0.861, respectively, with a significant performance (P<0.001 for all). Conclusion We could conclude that increased serum levels of FC along with increased levels of low-density lipoprotein cholesterol and decreased levels of high-density lipoprotein cholesterol have significant correlations to the increased severity of hepatic steatosis in NAFLD.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133123885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetal main pulmonary artery Doppler and prediction of lung maturity 胎儿肺动脉主动脉多普勒与肺成熟度预测

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_46_22

Safaa Kandil, Rasha Elshafey, Hesham Eltokhi, B. Eldeeb

{"title":"Fetal main pulmonary artery Doppler and prediction of lung maturity","authors":"Safaa Kandil, Rasha Elshafey, Hesham Eltokhi, B. Eldeeb","doi":"10.4103/tmj.tmj_46_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_46_22","url":null,"abstract":"Background Respiratory distress syndrome (RDS) in newborns occurs owing to surfactant deficiency. Decrease in quantity and quality of surfactant in lungs results in diminished surfactant activity. It affects not only preterm neonates but also term ones. RDS is a serious condition as it can lead to many neonatal comorbidities and even death. Doppler ultrasound is a noninvasive tool used for assessment of fetal biometry, so Doppler of pulmonary artery can be used safely in assessment of fetal lung maturity. Aim The purpose of our study was to assess the significance of fetal pulmonary artery Doppler in predicting lung maturity. Patients and methods A total of 50 pregnant women participated in this study with gestational age ranging from 34 to 39 weeks who were referred to the Diagnostic Radiology Department at Tanta University Hospitals during the period between December 2019 and December 2021. Results From the 50 pregnant women included in this study, six fetuses developed RDS. The greatest correlation was found with acceleration time/ejection time (AT/ET) ratio and resistive index (RI) with high sensitivity and specificity (P=0.000 and P<0.001, respectively). A cutoff value AT/ET less than 0.297 and RI more than 0.889 predicted RDS with sensitivity of 94.8 and 89.1%, respectively, and specificity of 83.5 and 78.2%, respectively. Conclusion Neonatal RDS can be predicted by pulmonary artery AT/ET ratio and RI with high sensitivity and specificity.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114992395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of antagonistic activity of an Egyptian probiotic Lactobacillus plantarum against bacteria isolated from ready-to-eat meat products 埃及益生菌植物乳杆菌对即食肉制品中分离的细菌拮抗活性的评价

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_64_19

Aya Radwan, W. Naghy, Abeer Shahbab, Aziza Hassan

{"title":"Evaluation of antagonistic activity of an Egyptian probiotic Lactobacillus plantarum against bacteria isolated from ready-to-eat meat products","authors":"Aya Radwan, W. Naghy, Abeer Shahbab, Aziza Hassan","doi":"10.4103/tmj.tmj_64_19","DOIUrl":"https://doi.org/10.4103/tmj.tmj_64_19","url":null,"abstract":"Background The increase in the incidence of antibiotic-resistant pathogens calls for strenuous efforts to substitute the administration of antibiotics with the use of probiotics. Aim The aim of the study was to evaluate the bacterial contamination of ready-to-eat meat products in Tanta city, determine the antibiotic susceptibility of the isolates, determine in vitro antagonistic effect of a probiotic Lactobacillus plantarum (L. plantarum) against isolates, and compare this effect with the inhibitory effect of the commonly used antibiotics. Materials and Methods The samples were collected in stomacher packs, homogenized, and serially diluted. Identification of pathogenic bacteria was done via standard microbiological methods. Antibiotic-sensitivity tests were done by disk-diffusion method. The results were compared with the inhibitory effect of L. plantarum done by well-diffusion and overlay methods. Results The total rate of bacterial contamination of the collected samples was 72/90 (80%), while the contamination rates from good sanitation-state (GS) outlets and poor sanitation-state (PS) outlets were 27/37 (72.9%) and 45/53 (84.9%), respectively. The most isolated bacteria were Escherichia coli (E. coli) (29%) followed by Staphylococcus aureus (21%). L. plantarum showed inhibitory effect against both Gram-positive and Gram-negative isolates. Its activity was maximum against E. coli and least for Klebsiella spp. in both well-diffusion and overlay methods. Conclusion The presence of pathogenic bacteria in ready-to-eat products is a great public health issue; also, this research supports the promising use of the tested L. plantarum and its products as antimicrobial agents against foodborne pathogen.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"11 Suppl 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126064835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Palpebral fissure changes following horizontal recti muscles surgery 水平直肌手术后睑裂的改变

Tanta Medical Journal Pub Date : 2023-01-01 DOI: 10.4103/tmj.tmj_42_22

Wafaa El Zahar, Heba M. Shafik, A. Awara, Mohamed El Desouky

{"title":"Palpebral fissure changes following horizontal recti muscles surgery","authors":"Wafaa El Zahar, Heba M. Shafik, A. Awara, Mohamed El Desouky","doi":"10.4103/tmj.tmj_42_22","DOIUrl":"https://doi.org/10.4103/tmj.tmj_42_22","url":null,"abstract":"Background Strabismus surgery is a 1-day operation. It can result in aligned eyes or nearly so (orthophoria) or overcorrection or undercorrection that may require further treatment or another surgery. Aim To assess alterations in vertical palpebral fissure height following horizontal recti muscle surgery (recession or resection) for the treatment of horizontal strabismus (esotropia or exotropia). Patients and methods A prospective interventional case series was carried out on 68 eyes of 41 patients with horizontal strabismus (exotropia or esotropia), comitant or incomitant (paralytic), who underwent surgical correction. Patients were subdivided into three groups: group I (n=50) underwent recession only, group II (n=10) underwent resection only, and group III (n=8) underwent recession and resection. All patients were subjected to preoperative, operative, and postoperative evaluations (palpebral fissure height and width measurement). Results Distant angle of exotropia was considerably lower in group I than group III (P2<0.019) but were insignificantly different between groups I and II and between groups II and III. Palpebral fissure at 6 months was considerably lower in group II than groups I and III (P=0.013 and 0.019, respectively). Conclusion Horizontal rectus muscles recession for horizontal strabismus causes vertical widening of palpebral fissure height, and also resection results in narrowing of vertical palpebral fissure height. The combination of horizontal rectus muscle recession and resection for horizontal strabismus results in vertical palpebral fissure height widening in half of eyes and vertical palpebral fissure height narrowing in a quarter of the eyes.","PeriodicalId":223545,"journal":{"name":"Tanta Medical Journal","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132139756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0