{"title":"Quality of Life After Video Laparoscopic Segmentary Colectomy for Intestinal Endometriosis","authors":"D. Germini","doi":"10.37191/mapsci-actcr-1(2)-11","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(2)-11","url":null,"abstract":"Background: Intestinal endometriosis (IE) is a chronic estrogen-dependent disease characterized by endometrial stroma outside the uterine cavity. It affects 10 to 15% of women and may present with pelvic pain and worsening quality of life. Treatment can be surgical, such as video laparoscopic segmental colectomy (VSC).\u0000\u0000Objective: To evaluate the quality of life of patients after VSC for treatment of intestinal endometriosis.\u0000\u0000Method: This is an observational, longitudinal, and retrospective study carried out through a review of medical records and a telephone interview with patients who underwent laparoscopic segmental colectomy in a private hospital between 2016 and 2020.\u0000\u0000Results: 43 patients were studied, of whom 30 (70%) complained of having impaired daily activities. Before surgery, dysmenorrhea intensity was classified as mild, moderate, severe, and very severe pain, with one patient (2.33%) classified as mild, three patients (6.98%) as moderate, 16 patients (37.2%) as severe, and 23 (53.49%) as very severe. As for pain during sexual intercourse, 13 patients (30%) reported dyspareunia. After surgery, 100% of the patients reported improvement in the complaint, referring to maintaining a normal routine after the VSC; of the 13 patients who did not feel that they had any impairment in their daily activities before the surgery, 2 still reported feeling more lively in their routine after having undergone surgery (P<.05). As for the intensity of dysmenorrhea after surgery, one (2.33%) patient classified it as moderate and 42 (97.67%) as mild (P<.05), indicating that there is a difference in pain intensity before and after surgery. Of the patients who previously reported dyspareunia, it was observed that 100% of them reported improvement after VSC with P=.0002.\u0000\u0000Conclusion: CSV can improve the quality of life of patients with intestinal endometriosis.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121289958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metastases its Biologics and Impact in Internal Medicine","authors":"D. Gandía","doi":"10.37191/mapsci-actcr-1(2)-9","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(2)-9","url":null,"abstract":"Cancer Metastases (Mets), the dissemination and growth of tumor cells at distant sites of the primary tumor, is a very complex Biological and Clinical process, that when intractable, leads most of the times to the patient death. Mets are the Cancer paradigm and is still a “prohibited” word in many parts of the world´s societies [1,2]. Cancer adjuvant or metastases-preventing therapies, such as Chemotherapy (Chemo) and nowadays Immunotherapy (Immune) give impressive survival rates results.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115115752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Spontaneous Calf Hematoma with Simultaneous Deep Venous Thrombosis","authors":"Jennifer Klein","doi":"10.37191/mapsci-actcr-1(2)-10","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(2)-10","url":null,"abstract":"Patients with active cancer may also have a state of hypercoagulability that increases their risk of venous thromboembolism (VTE). Enoxaparin is a low-molecular weight heparin (LMWH) that is indicated for the prevention and treatment of VTE and is the preferred agent for patients with cancer because of its lower risk of bleeding events and less drug interactions. Bleeding events such as muscular hematomas have been reported with the use of enoxaparin. The risk of hematoma is increased in those with certain risk factors that are frequently present in patients with active malignancy. Coagulation parameters are typically normal in patients with hematoma and there are no accepted criteria to predict which hematomas may become life-threatening. As hematomas present similarly to deep venous thrombosis (DVT), imaging is needed to distinguish them from one another as the treatment for one can worsen the other. Here we present a case of a woman with ovarian cancer and increasing clot burden of chronic diffuse VTE who developed a right calf hematoma while on chronic therapeutic enoxaparin.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127268046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fontanelles and Sutures: From Theory to Practice, A Literature Review","authors":"Paula V Palacino D","doi":"10.37191/mapsci-actcr-1(2)-7","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(2)-7","url":null,"abstract":"The development of the skull is an important event that begins from the moment of gestation to adulthood, two structures are important for it: sutures and fontanelles, their closure either early or late can lead to different pathologies of great importance, which many of them have treatment and some can even be prevented, for this reason, a revision of the sutures and fontanelles is carried out from their basic principles to the pathologies caused.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126735680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emergencies in Oncology","authors":"A. Hunis","doi":"10.37191/10.37191/mapsci-actcr-1(2)-8","DOIUrl":"https://doi.org/10.37191/10.37191/mapsci-actcr-1(2)-8","url":null,"abstract":"Oncological emergencies are defined as any acute possible morbid or life-threatening events in patients with cancer either because of the malignancy or because of their treatment. With advances in antitumor therapy, the prognosis of oncological diseases has improved, so the management of their complications, whether due to the tumors themselves or their respective treatments, becomes more important day by day. These events may occur at any time during malignancy, from symptoms present to end-stage disease. Metabolic syndromes include Tumor Lysis Syndrome and Hypercalcemia. Compression Syndromes includes Superior Vena Cava Syndrome and Spinal Cord Compression Syndrome.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"56 5-6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120905993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-intubation Tracheoesophageal Fistula In Severe Sars-cov-2 Covid-19 Patient: An Unexpected Finding During Swallowing Test","authors":"F. Elli","doi":"10.37191/mapsci-actcr-1(1)-6","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(1)-6","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) has cause the COVID-19 pandemic that had led to an increase in intensive care unit admission for massive interstitial pneumonia. Many patients underwent mechanical ventilation and endotracheal intubation for a prolonged period of time followed by a subsequent tracheostomy. The most common complications related to these maneuvers are stenosis, malacia, laryngotracheal granulomas, webs. The least common complications are tracheal necrosis due to tracheo-arterial or trachea-esophageal fistulas, caused by compression between the nasogastric tube and the orotracheal tube cuff.\u0000\u0000A case of 58-year-old female COVID-19 patient with severe pneumonia who underwent prolonged mechanical ventilation and intubation and for two months with unexplained episodes of food inhalation. During the swallowing test, it was observed inhalation, without natural passage of food from the glottic plane. Therefore, ENT specialist in swallowing, suspecting the feared tracheo-esophageal fistula, requested a double contrast esophageal x-ray that confirmed the diagnostic hypothesis. Thoracic surgery team performed surgical correction by resection and tracheal anastomosis with esophagoraffia.\u0000\u0000TEF is a very rare, but potentially fatal, complication of invasive VM. Predisposing factors are prolonged periods of invasive VM, elevated cuff pressures, oversized endotracheal tubes, patient comorbidities, local and general infections, use of a nasogastric tube.\u0000\u0000The endoscopic swallow test is a relatively simple test, performed at the patient's bed, that can identify oropharyngeal swallowing disorders and esophageal changes, such as tracheoesophageal fistula.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124713968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment Of Non-aesthetic Facial Veins: A Case Study Of The Combined Method Of Laser With Polidocanol Foam","authors":"G. Foureaux","doi":"10.37191/mapsci-actcr-1(1)-5","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(1)-5","url":null,"abstract":"Background: The veins in the frontal region of the face, Right Supratrochlear Vein, and Left Supratrochlear Vein can become exaggeratedly dilated in situations of emotion (crying or smiling), stress, physical exertion, lowering the head and other situations that can cause great embarrassment. Nd:Yag 1064nm is the most versatile LASER for the treatment of facial vessels, and can be used in telangiectasias and reticular veins. It’s different spot size and pulse duration settings allow the most suitable parameterization for different types of veins. Due to its ease, practicality of use and for delivering good results, sclerotherapy is still the gold standard technique for sclerosis of varicose veins and telangiectasias. The 1064 nm Nd:YAG LASER is also efficient. Its limit is more restricted in veins of larger caliber (>3mm) and faster flow and, for physical reasons, the distance from the varicose vein to the skin should not exceed 3.5mm to 4mm. The pain at high fluences, the higher cost and the occurrence of relapses when used alone, make us opt for combined therapies in some situations.\u0000\u0000Case: Patient P.B.C, female, 43 years old, dancer, without previous comorbidities. She looked for an outpatient doctor with vascular care in February/2022 with a complaint of discomfort due to the forehead, with significant vessel dilation after physical exercise. Physical examination showed a dilated right and left supratrochlear veins. The treatment of sclerotherapy with polidocanol foam associated with the QS Nd:YAG 1064nm laser was indicated.\u0000\u0000Conclusion: Sclerotherapy associated with selective and immediate photo thermolysis, using the long-pulse Nd:YAG 1064 LASER increases the efficiency of the treatment of varicose veins, reducing possible complications when any of the techniques are used in isolation.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129795784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronavirus, Immunity And Vaccination","authors":"Sara Amine","doi":"10.37191/mapsci-actcr-1(1)-3","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(1)-3","url":null,"abstract":"The central purpose of this article is to understand what the coronavirus is and how people can fight against this virus. Every person can get coronavirus and getting hospitalization, severe signs and in sometimes death. To avoid all these risks, several factors and conditions are important to have a good immune system that can fight against any type of viruses especially coronavirus. After 2 years of this pandemic, doctors and associations conclude that the best way to stay safe is to take the vaccine. In addition to the vaccine, a good and healthy lifestyle can also improve the immune system. The review highlights the important information like the signs of weakness of the immune system, how to improve it and what are the steps that should be taken to protect others when getting coronavirus.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129257050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Covid-19 Vaccines: Efficacy, Safety, And Side Effects","authors":"R. Bitar","doi":"10.37191/mapsci-actcr-1(1)-4","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(1)-4","url":null,"abstract":"Coronaviruses are a type of virus. There are many different kinds, and some cause disease. A coronavirus identified in 2019, SARS-CoV-2, has caused a pandemic of respiratory illness, called COVID-19. Coronavirus disease (COVID-19) is associate communicable disease caused by the SARS- CoV-2 virus. The general public infected with the virus can expertise delicate to moderate respiratory disorder and recover while not requiring special treatment. Anyone can get sick with COVID-19 and become seriously ill or die at any age. The virus can unfold from an infected person’s mouth or nose in tiny liquid particles after they cough, sneeze, speak, or breathe. However, some will become seriously ill and need medical attention. The short review discusses the ways to prevent to prevent and slow down transmission, different types of vaccine available and their effectiveness and the emergence need to get vaccinated.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117319899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Note- Archives Of Clinical Trials And Case Reports","authors":"A. Hunis","doi":"10.37191/mapsci-actcr-1(1)-2","DOIUrl":"https://doi.org/10.37191/mapsci-actcr-1(1)-2","url":null,"abstract":"We are experiencing a unique and unprecedented moment in the field of medicine in general and that of oncology in particular. Research and technological innovations are the drivers of great progress in the fight against cancer. Unfortunately, all these advances, during the years 2020 and 2021 were in \"pause\" mode because the world is experiencing a pandemic, but the fight and research in oncology continue. However, if we add this infection to the most common infectious diseases, the sum of all of them -I insist- does not reach the almost 10 million deaths from cancer that occur per year, in the world. The increase in life expectancy, the best and most accurate diagnostic methods, environmental carcinogens, lifestyle, low physical activity, viruses with oncogenic capacity and a whole series of factors that seem to play a key role in the development of these oncological diseases, called “cancer”, explain this enormous number of annual deaths, to which I previously referred.","PeriodicalId":223531,"journal":{"name":"Archives of Clinical Trials and Case Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127603393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}