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Fragile X-associated conditions: implications for the whole family 脆弱的x相关条件:对整个家庭的影响
The British Journal of General Practice Pub Date : 2019-08-29 DOI: 10.3399/bjgp19X705425
A. McKechanie, A. Barnicoat, I. Trender‐Gerhard, M. Allison, A. Stanfield
{"title":"Fragile X-associated conditions: implications for the whole family","authors":"A. McKechanie, A. Barnicoat, I. Trender‐Gerhard, M. Allison, A. Stanfield","doi":"10.3399/bjgp19X705425","DOIUrl":"https://doi.org/10.3399/bjgp19X705425","url":null,"abstract":"Fragile X syndrome (FXS) is a triplet-repeat expansion disorder of the X chromosome, with repeats of more than 200 (sometimes referred to as the full mutation) causing FXS and ∼59–200 repeats (the so-called premutation) being responsible for a variety of clinical presentations. Clinicians in primary care should be aware of these conditions and in particular be vigilant for common comorbidities to allow for early treatment. This article summarises the common issues for individuals with FXS and carriers of the premutation.\u0000\u0000FXS is the most common inherited cause of intellectual disability, occurring in approximately 1 in 3000–4000 males and 1 in 6000–8000 females. Although the genetic underpinnings of FXS are similar across individuals, the manifestations vary widely and in some ways there is no ‘typical’ presentation. Nonetheless, males with the syndrome generally have an intellectual disability ranging from mild to severe, whereas females are much more variably affected (due to random X-inactivation) and can range from being essentially asymptomatic to having a severe intellectual disability. There are a number of common physical comorbidities associated with the syndrome including epilepsy (∼25%), mitral valve prolapse (≤80%), hyperextensible joints, and an increased risk of inguinal hernias. Anxiety, attention deficit hyperactivity disorder (ADHD), and autism spectrum disorders (ASDs) are also significantly more common. Hyperarousal and sensory hypersensitivity are frequent symptoms, which may occur across a range of diagnoses. It is worth noting that, although one-third to two-thirds of individuals with FXS may meet criteria for an ASD, the presentation often varies subtly from that seen in idiopathic ASDs. In particular, some traits such as social difficulties and atypical eye contact may have very different underpinnings in FXS as compared with ASDs. …","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"69 1","pages":"460 - 461"},"PeriodicalIF":0.0,"publicationDate":"2019-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81573848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Antibiotic exposure and 'response failure' for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care. 抗生素暴露和随后呼吸道感染的“反应失败”:一项对英国初级保健学龄前儿童的观察性队列研究。
The British Journal of General Practice Pub Date : 2019-08-29 Print Date: 2019-09-01 DOI: 10.3399/bjgp19X705089
Oliver van Hecke, Alice Fuller, Clare Bankhead, Sara Jenkins-Jones, Nick Francis, Michael Moore, Chris Butler, Kay Wang
{"title":"Antibiotic exposure and 'response failure' for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care.","authors":"Oliver van Hecke, Alice Fuller, Clare Bankhead, Sara Jenkins-Jones, Nick Francis, Michael Moore, Chris Butler, Kay Wang","doi":"10.3399/bjgp19X705089","DOIUrl":"10.3399/bjgp19X705089","url":null,"abstract":"<p><strong>Background: </strong>Childhood antibiotic exposure has important clinically relevant implications. These include disruption to the microbiome, antibiotic resistance, and clinical workload manifesting as treatment 'failure'.</p><p><strong>Aim: </strong>To examine the relationship between the number of antibiotic courses prescribed to preschool children for acute respiratory tract infections (RTI), in the preceding year, and subsequent RTIs that failed to respond to antibiotic treatment ('response failures').</p><p><strong>Design and setting: </strong>A cohort study using UK primary care data from the Clinical Practice Research Datalink, 2009 to 2016.</p><p><strong>Method: </strong>Children aged 12 to 60 months (1 to 5 years) who were prescribed an antibiotic for an acute RTI (upper and lower RTI or otitis media) were included. One random index antibiotic course for RTI per child was selected. Exposure was the number of antibiotic prescriptions for acute RTI up to 12 months before the index antibiotic prescription. The outcome was 'response failure' up to 14 days after index antibiotic prescription, defined as: subsequent antibiotic prescription; referral; hospital admission; death; or emergency department attendance within 3 days. The authors used logistic regression models to estimate the odds between antibiotic exposure and response failure.</p><p><strong>Results: </strong>Out of 114 329 children who were prescribed an antibiotic course for acute RTI, children who received ≥2 antibiotic courses for acute RTIs in the preceding year had greater odds of response failure; one antibiotic course: adjusted odds ratio (OR) 1.03 (95% confidence interval [CI] = 0.88 to 1.21), <i>P</i> = 0.67, <i>n</i> = 230 children; ≥2 antibiotic courses: adjusted OR 1.32 (CI = 1.04 to 1.66), <i>P</i> = 0.02, <i>n</i> = 97.</p><p><strong>Conclusion: </strong>Childhood antibiotic exposure for acute RTI may be a good predictor for subsequent response failure (but not necessarily because of antibiotic treatment failure). Further research is needed to improve understanding of the mechanisms underlying response failure.</p>","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"45 1","pages":"e638-e646"},"PeriodicalIF":0.0,"publicationDate":"2019-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78577074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient preferences for management of high blood pressure in the UK: a discrete choice experiment 英国患者对高血压管理的偏好:离散选择实验
The British Journal of General Practice Pub Date : 2019-08-12 DOI: 10.3399/bjgp19X705101
B. Fletcher, Lisa Hinton, R. McManus, Oliver Rivero-Arias
{"title":"Patient preferences for management of high blood pressure in the UK: a discrete choice experiment","authors":"B. Fletcher, Lisa Hinton, R. McManus, Oliver Rivero-Arias","doi":"10.3399/bjgp19X705101","DOIUrl":"https://doi.org/10.3399/bjgp19X705101","url":null,"abstract":"Background With a variety of potentially effective hypertension management options, it is important to determine how patients value different models of care, and the relative importance of factors in their decision-making process. Aim To explore patient preferences for the management of hypertension in the UK. Design and setting Online survey of patients who have hypertension in the UK including an unlabelled discrete choice experiment (DCE). Method A DCE was developed to assess patient preferences for the management of hypertension based on four attributes: model of care, frequency of blood pressure (BP) measurement, reduction in 5-year cardiovascular risk, and costs to the NHS. A mixed logit model was used to estimate preferences, willingness-to-pay was modelled, and a scenario analysis was conducted to evaluate the impact of changes in attribute levels on the uptake of different models of care. Results One hundred and sixty-seven participants completed the DCE (aged 61.4 years, 45.0% female, 82.0% >5 years since diagnosis). All four attributes were significant in choice (P<0.05). Reduction in 5-year cardiovascular risk was the main driver of patient preference as evidenced in the scenario and willingness-to-pay analyses. GP management was significantly preferred over self-management. Patients preferred scenarios with more frequent BP measurement, and lower costs to the NHS. Conclusion Participants had similar preferences for GP management, pharmacist management, and telehealth, but a negative preference for self-management. When introducing new models of care for hypertension to patients, discussion of the potential benefits in terms of risk reduction should be prioritised to maximise uptake.","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"16 1","pages":"e629 - e637"},"PeriodicalIF":0.0,"publicationDate":"2019-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84032703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Outcomes of hospital admissions among frail older people: a 2-year cohort study 体弱老年人住院治疗的结果:一项为期2年的队列研究
The British Journal of General Practice Pub Date : 2019-07-16 DOI: 10.3399/bjgp19X704621
Eilís Keeble, H. Roberts, Christopher Williams, J. V. van Oppen, S. Conroy
{"title":"Outcomes of hospital admissions among frail older people: a 2-year cohort study","authors":"Eilís Keeble, H. Roberts, Christopher Williams, J. V. van Oppen, S. Conroy","doi":"10.3399/bjgp19X704621","DOIUrl":"https://doi.org/10.3399/bjgp19X704621","url":null,"abstract":"Background ‘Frailty crises’ are a common cause of hospital admission among older people and there is significant focus on admission avoidance. However, identifying frailty before a crisis occurs is challenging, making it difficult to effectively target community services. Better longer-term outcome data are needed if services are to reflect the needs of the growing population of older people with frailty. Aim To determine long-term outcomes of older people discharged from hospital following short (<72 hours) and longer hospital admissions compared by frailty status. Design and setting Two populations aged ≥70 years discharged from hospital units: those following short ‘ambulatory’ admissions (<72 hours) and those following longer inpatient stays. Method Data for 2-year mortality and hospital use were compared using frailty measures derived from clinical and hospital data. Results Mortality after 2 years was increased for frail compared with non-frail individuals in both cohorts. Patients in the ambulatory cohort classified as frail had increased mortality (Rockwood hazard ratio 2.3 [95% confidence interval {CI} = 1.5 to 3.4]) and hospital use (Rockwood rate ratio 2.1 [95% CI = 1.7 to 2.6]) compared with those patients classified as non-frail. Conclusion Individuals with frailty who are discharged from hospital experience increased mortality and resource use, even after short ‘ambulatory’ admissions. This is an easily identifiable group that is at increased risk of poor outcomes. Health and social care systems might wish to examine their current care response for frail older people discharged from hospital. There may be value in a ‘secondary prevention’ approach to frailty crises targeting individuals who are discharged from hospital.","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"56 1","pages":"e555 - e560"},"PeriodicalIF":0.0,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91081124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 52
Prevalence, characteristics, and patterns of patients with multimorbidity in primary care: a retrospective cohort analysis in Canada 加拿大初级保健中多病患者的患病率、特征和模式:一项回顾性队列分析
The British Journal of General Practice Pub Date : 2019-07-15 DOI: 10.3399/bjgp19X704657
K. Nicholson, A. Terry, M. Fortin, T. Williamson, Michael A Bauer, A. Thind
{"title":"Prevalence, characteristics, and patterns of patients with multimorbidity in primary care: a retrospective cohort analysis in Canada","authors":"K. Nicholson, A. Terry, M. Fortin, T. Williamson, Michael A Bauer, A. Thind","doi":"10.3399/bjgp19X704657","DOIUrl":"https://doi.org/10.3399/bjgp19X704657","url":null,"abstract":"Background Multimorbidity is a complex issue in modern medicine and a more nuanced understanding of how this phenomenon occurs over time is needed. Aim To determine the prevalence, characteristics, and patterns of patients living with multimorbidity, specifically the unique combinations (unordered patterns) and unique permutations (ordered patterns) of multimorbidity in primary care. Design and setting A retrospective cohort analysis of the prospectively collected data from 1990 to 2013 from the Canadian Primary Care Sentinel Surveillance Network electronic medical record database. Method Adult primary care patients who were aged ≥18 years at their first recorded encounter were followed over time. A list of 20 chronic condition categories was used to detect multimorbidity. Computational analyses were conducted using the Multimorbidity Cluster Analysis Tool to identify all combinations and permutations. Results Multimorbidity, defined as two or more and three or more chronic conditions, was prevalent among adult primary care patients and most of these patients were aged <65 years. Among female patients with two or more chronic conditions, 6075 combinations and 14 891 permutations were detected. Among male patients with three or more chronic conditions, 4296 combinations and 9716 permutations were detected. While specific patterns were identified, combinations and permutations became increasingly rare as the total number of chronic conditions and patient age increased. Conclusion This research confirms that multimorbidity is common in primary care and provides empirical evidence that clinical management requires a tailored, patient-centred approach. While the prevalence of multimorbidity was found to increase with increasing patient age, the largest proportion of patients with multimorbidity in this study were aged <65 years.","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"16 1","pages":"e647 - e656"},"PeriodicalIF":0.0,"publicationDate":"2019-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84698975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 40
Juggling confidentiality and safety: a qualitative study of how general practice clinicians document domestic violence in families with children 兼顾保密和安全:一项关于全科医生如何记录有孩子家庭暴力的定性研究
The British Journal of General Practice Pub Date : 2017-01-31 DOI: 10.3399/bjgp17X689353
Jessica Drinkwater, N. Stanley, E. Szilassy, C. Larkins, M. Hester, G. Feder
{"title":"Juggling confidentiality and safety: a qualitative study of how general practice clinicians document domestic violence in families with children","authors":"Jessica Drinkwater, N. Stanley, E. Szilassy, C. Larkins, M. Hester, G. Feder","doi":"10.3399/bjgp17X689353","DOIUrl":"https://doi.org/10.3399/bjgp17X689353","url":null,"abstract":"Background Domestic violence and abuse (DVA) and child safeguarding are interlinked problems, impacting on all family members. Documenting in electronic patient records (EPRs) is an important part of managing these families. Current evidence and guidance, however, treats DVA and child safeguarding separately. This does not reflect the complexity clinicians face when documenting both issues in one family. Aim To explore how and why general practice clinicians document DVA in families with children. Design and setting A qualitative interview study using vignettes with GPs and practice nurses (PNs) in England. Method Semi-structured telephone interviews with 54 clinicians (42 GPs and 12 PNs) were conducted across six sites in England. Data were analysed thematically using a coding frame incorporating concepts from the literature and emerging themes. Results Most clinicians recognised DVA and its impact on child safeguarding, but struggled to work out the best way to document it. They described tensions among the different roles of the EPR: a legal document; providing continuity of care; information sharing to improve safety; and a patient-owned record. This led to strategies to hide information, so that it was only available to other clinicians. Conclusion Managing DVA in families with children is complex and challenging for general practice clinicians. National integrated guidance is urgently needed regarding how clinicians should manage the competing roles of the EPR, while maintaining safety of the whole family, especially in the context of online EPRs and patient access.","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"1 1","pages":"e437 - e444"},"PeriodicalIF":0.0,"publicationDate":"2017-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83754463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Diagnostic accuracy of GPs when using an early-intervention decision support system: a high-fidelity simulation 全科医生在使用早期干预决策支持系统时的诊断准确性:高保真度模拟
The British Journal of General Practice Pub Date : 2017-01-31 DOI: 10.3399/bjgp16X688417
O. Kostopoulou, Talya Porat, Derek Corrigan, Samhar Mahmoud, B. Delaney
{"title":"Diagnostic accuracy of GPs when using an early-intervention decision support system: a high-fidelity simulation","authors":"O. Kostopoulou, Talya Porat, Derek Corrigan, Samhar Mahmoud, B. Delaney","doi":"10.3399/bjgp16X688417","DOIUrl":"https://doi.org/10.3399/bjgp16X688417","url":null,"abstract":"Background Observational and experimental studies of the diagnostic task have demonstrated the importance of the first hypotheses that come to mind for accurate diagnosis. A prototype decision support system (DSS) designed to support GPs’ first impressions has been integrated with a commercial electronic health record (EHR) system. Aim To evaluate the prototype DSS in a high-fidelity simulation. Design and setting Within-participant design: 34 GPs consulted with six standardised patients (actors) using their usual EHR. On a different day, GPs used the EHR with the integrated DSS to consult with six other patients, matched for difficulty and counterbalanced. Method Entering the reason for encounter triggered the DSS, which provided a patient-specific list of potential diagnoses, and supported coding of symptoms during the consultation. At each consultation, GPs recorded their diagnosis and management. At the end, they completed a usability questionnaire. The actors completed a satisfaction questionnaire after each consultation. Results There was an 8–9% absolute improvement in diagnostic accuracy when the DSS was used. This improvement was significant (odds ratio [OR] 1.41, 95% confidence interval [CI] = 1.13 to 1.77, P<0.01). There was no associated increase of investigations ordered or consultation length. GPs coded significantly more data when using the DSS (mean 12.35 with the DSS versus 1.64 without), and were generally satisfied with its usability. Patient satisfaction ratings were the same for consultations with and without the DSS. Conclusion The DSS prototype was successfully employed in simulated consultations of high fidelity, with no measurable influences on patient satisfaction. The substantially increased data coding can operate as motivation for future DSS adoption.","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"81 1","pages":"e201 - e208"},"PeriodicalIF":0.0,"publicationDate":"2017-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78991045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 46
Primary care screening for peripheral arterial disease: a cross-sectional observational study 外周动脉疾病的初级保健筛查:一项横断面观察研究
The British Journal of General Practice Pub Date : 2017-01-27 DOI: 10.3399/bjgp17X689137
Jane Davies, Jonathan Richards, K. Conway, J. Kenkre, J. Lewis, E. Mark Williams
{"title":"Primary care screening for peripheral arterial disease: a cross-sectional observational study","authors":"Jane Davies, Jonathan Richards, K. Conway, J. Kenkre, J. Lewis, E. Mark Williams","doi":"10.3399/bjgp17X689137","DOIUrl":"https://doi.org/10.3399/bjgp17X689137","url":null,"abstract":"Background Early identification of peripheral arterial disease (PAD) and subsequent instigation of risk modification strategies could minimise disease progression and reduce overall risk of cardiovascular (CV) mortality. However, the feasibility and value of primary care PAD screening is uncertain. Aim This study (the PIPETTE study — Peripheral arterial disease In Primary carE: Targeted screening and subsequenT managEment) aimed to determine the value of a proposed primary care PAD screening strategy. Outcomes assessed were: prevalence of PAD and agreement of ankle– brachial index (ABI)-defined PAD (ABI ≤0.9) with QRISK®2-defined high CV risk (≥20). Design and setting A cross-sectional observational study was undertaken in a large general practice in Merthyr Tydfil, Wales. Method In total, 1101 individuals with ≥2 pre-identified CV risk factors but no known CV disease or diabetes were invited to participate. Participants underwent ABI measurement and QRISK2 assessment, and completed Edinburgh Claudication Questionnaires. Results A total of 368 people participated in the study (participation rate: 33%). Prevalence of PAD was 3% (n = 12). The number needed to screen (NNS) to detect one new case of PAD was 31. Refining the study population to those aged ≥50 years with a smoking history reduced the NNS to 14, while still identifying 100% of PAD cases. Of participants with PAD, 33% reported severe lifestyle-limiting symptoms of intermittent claudication that warranted subsequent endovascular intervention, yet had not previously presented to their GP. The QRISK2 score predicted high CV risk in 92% of participants with PAD. Conclusion The low PAD yield and the fact that QRISK2 was largely comparable to the ABI in predicting high CV risk suggests that routine PAD screening may be unwarranted. Instead, strategies to improve public awareness of PAD are needed.","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"136 1","pages":"e103 - e110"},"PeriodicalIF":0.0,"publicationDate":"2017-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83523705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Secondary prevention lifestyle interventions initiated within 90 days after TIA or 'minor' stroke: a systematic review and meta-analysis of rehabilitation programmes. 在TIA或“轻微”中风后90天内开始二级预防生活方式干预:康复计划的系统回顾和荟萃分析。
The British Journal of General Practice Pub Date : 2017-01-01 Epub Date: 2016-12-05 DOI: 10.3399/bjgp16X688369
Neil Heron, Frank Kee, Christopher Cardwell, Mark A Tully, Michael Donnelly, Margaret E Cupples
{"title":"Secondary prevention lifestyle interventions initiated within 90 days after TIA or 'minor' stroke: a systematic review and meta-analysis of rehabilitation programmes.","authors":"Neil Heron, Frank Kee, Christopher Cardwell, Mark A Tully, Michael Donnelly, Margaret E Cupples","doi":"10.3399/bjgp16X688369","DOIUrl":"10.3399/bjgp16X688369","url":null,"abstract":"<p><strong>Background: </strong>Strokes are often preceded by a transient ischaemic attack (TIA) or 'minor' stroke. The immediate period after a TIA/minor stroke is a crucial time to initiate secondary prevention. However, the optimal approach to prevention, including non-pharmacological measures, after TIA is not clear.</p><p><strong>Aim: </strong>To systematically review evidence about the effectiveness of delivering secondary prevention, with lifestyle interventions, in comprehensive rehabilitation programmes, initiated within 90 days of a TIA/minor stroke. Also, to categorise the specific behaviour change techniques used.</p><p><strong>Design and setting: </strong>The review identified randomised controlled trials by searching the Cochrane Library, Ovid MEDLINE, Ovid EMBASE, Web of Science, EBSCO CINAHL and Ovid PsycINFO.</p><p><strong>Method: </strong>Two review authors independently screened titles and abstracts for eligibility (programmes initiated within 90 days of event; outcomes reported for TIA/minor stroke) and extracted relevant data from appraised studies; a meta-analysis was used to synthesise the results.</p><p><strong>Results: </strong>A total of 31 potentially eligible papers were identified and four studies, comprising 774 patients post-TIA or minor stroke, met the inclusion criteria; two had poor methodological quality. Individual studies reported increased aerobic capacity but meta-analysis found no significant change in resting and peak systolic blood pressure, resting heart rate, aerobic capacity, falls, or mortality. The main behaviour change techniques were goal setting and instructions about how to perform given behaviours.</p><p><strong>Conclusion: </strong>There is limited evidence of the effectiveness of early post-TIA rehabilitation programmes with preventive lifestyle interventions. Further robust randomised controlled trials of comprehensive rehabilitation programmes that promote secondary prevention and lifestyle modification immediately after a TIA are needed.</p>","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"25 1","pages":"e57-e66"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81343437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the relationship between consultation length and patient experience: a cross-sectional study in primary care. 调查会诊时间与患者经验之间的关系:一项初级保健的横断面研究。
The British Journal of General Practice Pub Date : 2016-12-01 Epub Date: 2016-10-24 DOI: 10.3399/bjgp16X687733
Natasha Elmore, Jenni Burt, Gary Abel, Frances A Maratos, Jane Montague, John Campbell, Martin Roland
{"title":"Investigating the relationship between consultation length and patient experience: a cross-sectional study in primary care.","authors":"Natasha Elmore, Jenni Burt, Gary Abel, Frances A Maratos, Jane Montague, John Campbell, Martin Roland","doi":"10.3399/bjgp16X687733","DOIUrl":"10.3399/bjgp16X687733","url":null,"abstract":"<p><strong>Background: </strong>Longer consultations in primary care have been linked with better quality of care and improved health-related outcomes. However, there is little evidence of any potential association between consultation length and patient experience.</p><p><strong>Aim: </strong>To examine the relationship between consultation length and patient-reported communication, trust and confidence in the doctor, and overall satisfaction.</p><p><strong>Design and setting: </strong>Analysis of 440 videorecorded consultations and associated patient experience questionnaires from 13 primary care practices in England.</p><p><strong>Method: </strong>Patients attending a face-to-face consultation with participating GPs consented to having their consultations videoed and completed a questionnaire. Consultation length was calculated from the videorecording. Linear regression (adjusting for patient and doctor demographics) was used to investigate associations between patient experience (overall communication, trust and confidence, and overall satisfaction) and consultation length.</p><p><strong>Results: </strong>There was no evidence that consultation length was associated with any of the three measures of patient experience (P >0.3 for all). Adjusted changes on a 0-100 scale per additional minute of consultation were: communication score 0.02 (95% confidence interval [CI] = -0.20 to 0.25), trust and confidence in the doctor 0.07 (95% CI = -0.27 to 0.41), and satisfaction -0.14 (95% CI = -0.46 to 0.18).</p><p><strong>Conclusion: </strong>The authors found no association between patient experience measures of communication and consultation length, and patients may sometimes report good experiences from very short consultations. However, longer consultations may be required to achieve clinical effectiveness and patient safety: aspects also important for achieving high quality of care. Future research should continue to study the benefits of longer consultations, particularly for patients with complex multiple conditions.</p>","PeriodicalId":22333,"journal":{"name":"The British Journal of General Practice","volume":"5 1","pages":"e896-e903"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80144139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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