Tetrahedron, asymmetry最新文献_第9页

Cumulative author index 累计作者索引

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-11-03 DOI: 10.1016/S0957-4166(17)30494-9

引用次数: 0

Best practice and pitfalls in absolute structure determination 确定绝对结构的最佳实践和陷阱

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-08-08 DOI: 10.1016/j.tetasy.2017.07.010

Anthony Linden

引用次数: 8

Strategies for using NMR spectroscopy to determine absolute configuration 使用核磁共振波谱确定绝对构型的策略

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-09-28 DOI: 10.1016/j.tetasy.2017.09.009

Thomas J. Wenzel

引用次数: 15

Stereochemistry abstracts 立体化学文摘

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-11-03 DOI: 10.1016/S0957-4166(17)30492-5

引用次数: 0

Special Issue in memory of Howard D Flack, who died suddenly in February 2017 纪念霍华德·D·弗莱克的特刊，他于2017年2月突然去世

Tetrahedron, asymmetry Pub Date : 2017-10-15 DOI: 10.1016/j.tetasy.2017.10.002

David J. Watkin

引用次数: 2

Some experimental aspects of absolute configuration determination using single crystal X-ray diffraction 用单晶x射线衍射测定绝对构型的一些实验方面

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-10-12 DOI: 10.1016/j.tetasy.2017.08.016

Amber L. Thompson , Sarah F. Jenkinson , George W.J. Fleet

引用次数: 5

Some new protocols for the assignment of absolute configuration by NMR spectroscopy using chiral solvating agents and CDAs 用手性溶剂化剂和cda进行核磁共振绝对构型的新方法

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-10-12 DOI: 10.1016/j.tetasy.2017.09.017

Sandeep Kumar Mishra, Nagarajarao Suryaprakash

{"title":"Some new protocols for the assignment of absolute configuration by NMR spectroscopy using chiral solvating agents and CDAs","authors":"Sandeep Kumar Mishra, Nagarajarao Suryaprakash","doi":"10.1016/j.tetasy.2017.09.017","DOIUrl":"10.1016/j.tetasy.2017.09.017","url":null,"abstract":"<div>The utility of enantiopure BINOL (1,10-Bi-2-naphthol), in a ternary ion-pair complex, which is obtained using a carboxylic acid and an organic base, as a versatile chiral solvating agent (CSA) has been demonstrated for chiral analysis and the absolute configuration assignment of hydroxy acids. Another protocol where the utility of NOBIN as a CSA has been developed for discrimination and absolute configuration assignment of acids, hydroxy acids and their derivatives with a distinct strategy where a third ingredient, p-toluenesulfonic acid (p-TsOH) serves as a linker. In addition some three component chiral derivatization protocols have been introduced, such as the use of 2-formylphenylboronic acid and enantiopure mandelic acid or a primary amine for the determination of the configuration of primary amines and hydroxy acids, respectively. A simple, rapid and highly efficient three component chiral derivatizing protocol has also been discussed which was developed for assigning the absolute configuration of chiral α-hydroxy acids and their derivatives, which involves the coupling of 2-formylphenylboronic acid with (R)-[1,1-binaphthalene]-2,2-diamine, and (S)-[1,1-binaphthalene]-2,2-diamine separately. In a few examples, the DFT based theoretical calculations have been carried out to determine the geometry optimized structures of the complexes.</div>","PeriodicalId":22237,"journal":{"name":"Tetrahedron, asymmetry","volume":"28 10","pages":"Pages 1220-1232"},"PeriodicalIF":0.0,"publicationDate":"2017-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.tetasy.2017.09.017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88605905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Ferrocene derivatives of liquid chiral molecules allow assignment of absolute configuration by X-ray crystallography 二茂铁衍生物的液体手性分子允许分配绝对构型的x射线晶体学

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-10-06 DOI: 10.1016/j.tetasy.2017.09.002

Philipp M. Holstein , Julian J. Holstein , Eduardo C. Escudero-Adán , Olivier Baudoin , Antonio M. Echavarren

引用次数: 14

Dual chiral silver catalyst in the synthetic approach to the core of hepatitis C virus inhibitor GSK 625433 using enantioselective 1,3-dipolar cycloaddition of azomethine ylides and electrophilic alkenes 双手性银催化剂在丙型肝炎病毒抑制剂GSK 625433的核心合成方法中采用对映选择性1,3-偶极环加成法将偶氮亚胺酰基与亲电烯烃结合

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-08-30 DOI: 10.1016/j.tetasy.2017.08.011

Ihssene Chabour , Luis M. Castelló , Juan Mancebo-Aracil , María Martín-Rodríguez , María de Gracia Retamosa , Carmen Nájera , José M. Sansano

引用次数: 5

Nucleophilic additions on acetyldioxanes derived from (−)-(1R)-myrtenal used as chiral auxiliaries: substituent effects on the stereochemical outcome 作为手性助剂的(−)-(1R)桃金娘醛衍生的乙酰二恶烷上的亲核加成物:取代基对立体化学结果的影响

Tetrahedron, asymmetry Pub Date : 2017-10-15 Epub Date: 2017-10-06 DOI: 10.1016/j.tetasy.2017.07.008

Elvia Becerra-Martínez , Francisco Ayala-Mata , Pedro Velázquez-Ponce , Manuel E. Medina , Hugo A. Jiménez-Vazquez , Pedro Joseph-Nathan , L. Gerardo Zepeda

{"title":"Nucleophilic additions on acetyldioxanes derived from (−)-(1R)-myrtenal used as chiral auxiliaries: substituent effects on the stereochemical outcome","authors":"Elvia Becerra-Martínez , Francisco Ayala-Mata , Pedro Velázquez-Ponce , Manuel E. Medina , Hugo A. Jiménez-Vazquez , Pedro Joseph-Nathan , L. Gerardo Zepeda","doi":"10.1016/j.tetasy.2017.07.008","DOIUrl":"10.1016/j.tetasy.2017.07.008","url":null,"abstract":"<div>The synthesis of acetyldioxanes 4 and 9a starting from (−)-(1R)-myrtenal is described. The products were treated with a representative series of nucleophilic reagents (RMgX, RLi, NaBH4 and LiAlH4) to assess the effect of the substituent at C-3 on the stereochemical outcome. It was observed that the nucleophiles preferred the re-face of the C<img>O group when the equatorial substituent at C-3 was a methyl group, whereas a phenyl group at the same position induced the addition through the si-face, thus allowing access to either desired stereochemistry of a final product. This behavior suggests that the formation of the expected Cram-chelated coordination complex takes a coplanar orientation with the C-3 equatorial substituent. Moreover, Grignard reagents were the most stereoselective nucleophiles. The stereochemistry of the addition was established by X-ray diffraction and chemical correlation.</div>","PeriodicalId":22237,"journal":{"name":"Tetrahedron, asymmetry","volume":"28 10","pages":"Pages 1350-1358"},"PeriodicalIF":0.0,"publicationDate":"2017-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.tetasy.2017.07.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76879328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3