{"title":"Ultrasound In-Body Communication with OFDM through Multipath Realistic Channels","authors":"Thomas Bos, W. Dehaene, M. Verhelst","doi":"10.1109/BIOCAS.2019.8918755","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8918755","url":null,"abstract":"Implanted medical devices need a reliable, low-energy and secure in-body communication link. Ultrasound wave propagation is promising over other techniques due to its lower body attenuation, inherent security and well-known health risks. While US communication systems have been developed for in-body communication, state-of-the-art systems fail to provide small-size solutions capable of operating under realistic channel conditions. This paper focuses on communication with small-scale (2 mm size) and omni-directional transducers (1.2 MHz center frequency), and discusses the high multipath delay in such channels. To cope with these channel characteristics, an ultrasound in-body optimized OFDM communication scheme is proposed and implemented. In experiments through real tissue, the modem achieves a bit error rate below 1e-4 until a throughput of 340 kbps across 10 cm of beef tissue.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"397 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121257786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sang Joon Kim, Joonseong Kang, Wonseok Lee, Jonghan Kim, Junyeub Suh, Chisung Bae, Hyungwoo Lee, Jongpal Kim, Seungchul Jung, Seok-Ju Yun, Young-Jun Hong, Hankyu Lee, Jaechun Lee, Seong Joong Kim
{"title":"Micro Bio Processor: a 0.144cc 70uW closed loop platform for body implant electroceutical systems","authors":"Sang Joon Kim, Joonseong Kang, Wonseok Lee, Jonghan Kim, Junyeub Suh, Chisung Bae, Hyungwoo Lee, Jongpal Kim, Seungchul Jung, Seok-Ju Yun, Young-Jun Hong, Hankyu Lee, Jaechun Lee, Seong Joong Kim","doi":"10.1109/BIOCAS.2019.8918718","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8918718","url":null,"abstract":"We propose a specialized platform for implantable close loop electroceutical; Micro Bio Processor, which supports neural sensing, stimulation, two reliable wireless connectivities, high efficient power management and wireless charging. The main functions are implemented in two chips and overall system is realized in 0.144cc volume module. The system operates for a week (70uW average) on a single charge with the smallest implant battery in typical closed loop treatment scenario.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127110931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ting-Hsuan Lin, Chun-Rong Huang, Hsiu‐Chi Cheng, B. Sheu
{"title":"Gastric Section Detection Based on Decision Fusion of Convolutional Neural Networks","authors":"Ting-Hsuan Lin, Chun-Rong Huang, Hsiu‐Chi Cheng, B. Sheu","doi":"10.1109/BIOCAS.2019.8919015","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8919015","url":null,"abstract":"To provide accurate histological parameter assessment of each gastric section from endoscopic images, gastric sections need to be correctly identified in advance. In this paper, we propose a novel CNN based ensemble learning method to detect gastric sections from endoscopic images by fusing decisions of multiple convolutional neural network (CNN) models which provide initial decision probability of the endoscopic image. The decision probability is concatenated and classified by a decision fusion network to achieve effective and efficient gastric section detection. In the experiments, we compare the proposed method with state-of-the-art CNN and CNN based ensemble learning methods and conclude that the proposed method owns the best testing accuracy.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114924435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fang-fu Chen, J. Müller, Jens Müller, Juliane Müller, M. Kirsch, R. Tetzlaff
{"title":"Motion Correction for Thermography using Co-registered Visual-Light Images","authors":"Fang-fu Chen, J. Müller, Jens Müller, Juliane Müller, M. Kirsch, R. Tetzlaff","doi":"10.1109/BIOCAS.2019.8918761","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8918761","url":null,"abstract":"Motion correction for intraoperative thermography is a great challenge. Both motion and physiological processes, such as heat transfer due to brain activity, are manifested in temperature variations. To unambiguously detect and correct motion, we employ co-registered visual-light images. Complementing our previous work, we propose a complete workflow and verify the methods by analysing breath and pulse frequencies before and after motion correction. Our approach is able to accurately correct motion without affecting physiological temperature shifts.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116771565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Swarnkar, U. Abeyratne, B. Duce, R. Sharan, C. Hukins, K. McCloy
{"title":"Night-Time Brain Inter-Hemispheric Asynchrony in Sleep Apnea Patients Carry Information on Neuropsychological Impairment","authors":"V. Swarnkar, U. Abeyratne, B. Duce, R. Sharan, C. Hukins, K. McCloy","doi":"10.1109/BIOCAS.2019.8919147","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8919147","url":null,"abstract":"Obstructive sleep apnea (OSA) is a serious sleep disorder with diurnal symptoms including neuropsychological impairments such as excessive daytime sleepiness and loss of attention. There are no efficient tools to measure these impairments in current clinical practice. In this paper, we explore the feasibility of measuring neuropsychological impairments using electroencephalography (EEG) data acquired during the standard clinical sleep diagnostic test known as polysomnography (PSG). We hypothesized that left-right hemispheric EEG asynchrony could quantitatively characterize neuropsychological impairment in OSA in a population of sleep laboratory patients. We acquired EEG data from 50 subjects undergoing routine PSG, using symmetric electrode derivations of C4-A2 and C3-A1. Their neuropsychological performance was assessed via a psychomotor vigilance task (PVT). We computed the left-right EEG asynchrony and developed a logistic regression model (LRM) to classify patients according to their PVT performance. Leave-one-out cross-validation studies on a LRM model with two-class PVT performance achieved a sensitivity of 83% (95% CI: 66-100%) and a specificity of 78% (95% CI: 64-92%). These results indicate that EEG asynchrony during sleep carries information on daytime neuropsychological impairments in OSA subjects.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128407275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serge Le Thanh, N. Lobato-Dauzier, F. Khoyratee, Romain Beaubois, T. Fujii, A. Genot, T. Levi
{"title":"Low power and massively parallel simulation of oscillatory biochemical networks on FPGA","authors":"Serge Le Thanh, N. Lobato-Dauzier, F. Khoyratee, Romain Beaubois, T. Fujii, A. Genot, T. Levi","doi":"10.1109/BIOCAS.2019.8919020","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8919020","url":null,"abstract":"Biological functions emerge from a multitude of chemical species woven into intricate biochemical networks. It is crucial to compute the dynamics of a biochemical network from its kinetics and topology. In order to reverse engineer networks and map their design space, dynamics needs to be simulated for many different parameters and topologies, leading to a combinatorial explosion that requires heavy computational power. To solve this issue, we show here an application of FPGA platform to simulate biochemical networks. As a toy model, we simulate a structurally simple network with a rich oscillatory dynamics: a predator-prey biochemical oscillators. The network mimics predator-prey dynamics. We show that FPGA can simulate the dynamics of PP faithfully. These results open the door to more energy-efficient simulations.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134638795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaan Sel, D. Kireev, Alexander Brown, Bassem Ibrahim, D. Akinwande, R. Jafari
{"title":"Electrical Characterization of Graphene-based e-Tattoos for Bio-Impedance-based Physiological Sensing","authors":"Kaan Sel, D. Kireev, Alexander Brown, Bassem Ibrahim, D. Akinwande, R. Jafari","doi":"10.1109/BIOCAS.2019.8919003","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8919003","url":null,"abstract":"Bio-impedance (Bio-Z) is a promising method to measure a plurality of physiological observations from the human body. The principal challenge, however, remains in the electrodes. Wet-electrodes are inconvenient to wear and drycontact electrodes do not provide sufficient robustness. The objective of this work is to demonstrate the feasibility of leveraging graphene-based electrodes to establish intimate contact with the skin while not introducing any discomfort to the user. Our proposed electrodes are ultrathin, soft, transparent, and can potentially remain on the skin at the same location over an extended period, while offering robust measurements. In this paper, we present the characterization of the proposed ultrathin and skin-conformable graphene-based electronic tattoos (GETs) in continuous Bio-Z measurements. Our bilayer GETs (biGETs) provide an average of contact impedance with the skin at 10 kHz, improving the contact impedance acquired from the traditional dry electrodes. Moreover, Bio-Z measurements with the GETs show less variation (3.6 average standard deviation, 6.5 maximum standard deviation with biGET) due to its stable contact to the reference wet electrode measurements (4.1 average standard deviation and 7.5 maximum standard deviation with wet electrodes). Compared to the traditional electrode structures, our proposed GETs provide better contact impedance, good adherence to the skin, robustness in sensing, and additional comfort and breathability.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124065902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BioCAS 2019 Table of Contents","authors":"","doi":"10.1109/biocas.2019.8919066","DOIUrl":"https://doi.org/10.1109/biocas.2019.8919066","url":null,"abstract":"","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121285016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Kassanos, F. Seichepine, D. Wales, Guang-Zhong Yang
{"title":"Towards a Flexible/Stretchable Multiparametric Sensing Device for Surgical and Wearable Applications","authors":"P. Kassanos, F. Seichepine, D. Wales, Guang-Zhong Yang","doi":"10.1109/BIOCAS.2019.8919197","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8919197","url":null,"abstract":"There have recently been tremendous advances in materials, fabrication methods and geometrical designs for flexible/stretchable electronics. Such technologies are critical for wearable, implantable, soft robotic and surgical devices. This paper presents a novel flexible/stretchable device, realized via a commercial process. This is comprised of horseshoe interconnects, electrochemical sensor electrode arrays, a heater for thermotherapy/thermo-regulation, a temperature sensor, electrodes for recording/applying signals to tissues and a bioimpedance sensor. Electrochemical deposition and characterization of platinum black to the bioimpedance sensor and gold and subsequently IrOx for pH sensing to other electrodes, characterization of the temperature and bioimpedance sensors and heater are presented.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129188454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A CMOS Lab-on-a-Chip for Fully Automated Telomerase Activity Detection","authors":"Stefano Sonedda, C. Napoli, M. Barbaro","doi":"10.1109/BIOCAS.2019.8918729","DOIUrl":"https://doi.org/10.1109/BIOCAS.2019.8918729","url":null,"abstract":"This paper presents a CMOS Lab-on-a-chip capable of implementing all the steps to detect the rate of activity of enzyme telomerase. Telomerase expression is a marker of malignity in tumoral cells and its evaluation can be exploited for early diagnosis of many types of cancer cells. In order to detect the enzyme, a CMOS device integrating 1024 biosensors able to measure kinetics of DNA replication and telomerase reaction was developed. Since the activation of telomerase occurs in a very precise temperature range, the chip includes integrated temperature sensors and heaters to precisely set the working temperature. The device was designed in a standard 0.18µm CMOS process from XFAB and includes A/D conversion and a complete digital interface, all integrated within a single chip. Post-layout simulations are provided.","PeriodicalId":222264,"journal":{"name":"2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129338902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}