Systematic Reviews in Pharmacy最新文献

{"title":"Frequency of Pulmonary Manifestations of in Patients with Gastroesophageal Reflux Disease","authors":"M. Liaqat, Khajista Zulfiqar, Waleed Asghar","doi":"10.31838/SRP.2021.5.11","DOIUrl":"https://doi.org/10.31838/SRP.2021.5.11","url":null,"abstract":"Introduction: Pulmonary manifestations of GERD are attracting increasing attention. The physiological link between GERD and pulmonary disease has been extensively studied in chronic cough and asthma. The gastric contents can cause throat irritation, postnasal drip and hoarseness also recurrent cough. Objectives: This study is to determine frequency of pulmonary manifestations in patients with Gastroesophageal Reflux Disease. Settings: This cross-sectional study was conducted in Aeer ud din Medical college during June 2019 to December 2019. All patients with heartburn, both males and females of 20-70 years of age. Results: Out of 150 patients’ laryngeal symptoms were 10% have dry cough 8% have hoarseness and dry cough hoarseness both in 10% in patients with heartburn. 34% patients with GERD were found to be asthmatic. Nasal symptoms were infrequent 2%. Out of 150 patients 36% do not have any pulmonary manifestations. Conclusion: There is high prevalence of pulmonary manifestations in patients with GERD.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"31 1","pages":"204-206"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87091603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Artificial Intelligence in Upper Gastrointestinal Diseases: Present and Future","authors":"Jin Lee","doi":"10.51268/SRP.2021.4.15","DOIUrl":"https://doi.org/10.51268/SRP.2021.4.15","url":null,"abstract":"There has been extensive research and progress in the medical application of Artificial Intelligence (AI) technology. Radiologic and endoscopic diagnosis based on image analysis has been one of the main areas of focus. In the field of Gastrointestinal (GI) endoscopy, AI has been applied to gastroscopy, capsule endoscopy, and colonoscopy. There are relatively fewer studies in which AI is applied to upper GI diseases, and analysis has mainly focused on the detection of esophageal or gastric neoplasms in upper GI endoscopy. AI is also used to assess the depth of cancer invasion, detect Helicobacter pylori (H. pylori) infection, and diagnose the characteristics of subepithelial lesions. In the near future, AI is expected to expand to the field of disease treatment.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"20 4 1","pages":"81-86"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85752009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Online Mass Media on Anti-Corruption Legal Awareness Education","authors":"Eddy Rifai, Pitriadin, A. Triono","doi":"10.31838/SRP.2021.2.60","DOIUrl":"https://doi.org/10.31838/SRP.2021.2.60","url":null,"abstract":"This research examines the influence of online mass media on anti-corruption legal awareness education. The study uses an empirical and normative juridical approach with calculations using chi-square statistics. The results showed that criminal law enforcement would run effectively if the community has legal awareness in combating crime. Online mass media can play a role in increasing the community's legal awareness through its duties and functions as a means of communication and information. Reading online mass media affects the legal awareness of anti-corruption society in the form of anti-corruption, a positive attitude towards anti-corruption, and perceptions of anti-corruption. Based on the calculation results, there is a significant difference between reading online mass media with anti-corruption legal awareness, which is realized through knowledge, positive attitude, and anti-corruption perception. There is a significant difference in level because some knowledgeable and have a positive attitude towards anti-corruption, lack an anti-corruption understanding.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"37 1","pages":"439-447"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85799576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of vitamins D and E acute supplementation on testosterone levels in male rats","authors":"A. G. Al-Charak, Z. Kadhim, Shaimaa H. Ali Al-Cekal","doi":"10.31838/SRP.2021.2.47","DOIUrl":"https://doi.org/10.31838/SRP.2021.2.47","url":null,"abstract":"Background and objective: In recent years, vitamin D has been considered an interesting subject of study due to its pleiotropic role including autocrine, paracrine and endocrine function in several target organs and systems. The essential molecule for reproduction in animals and it have an antioxidant properties in all mammalian cells is known vitamin E. This study aimed the study the effects of acute supplementation of both vitamins D and E on developing of testosterone levels and reproductive properties in rats. Methods: Forty rats were divided into four groups, 1st group were feeding by acute supplementation with vitamin D while 2nd group supplementation of vitamin E, 3rd group feeding with acute supplementation of both vitamins, and 4th group was control with normal fed. HPLC technique was used to assessing of vitamins D and E levels while levels of TES were investigated by ELISA. Results: The levels of vitamins D (ng/ml) levels in this experiment (after month of supplementation) of study groups (VDS, VES, VDES, and Control) were 7.27±2.1 ,3.15±1.1, 6.19±0.9, 5.11±1.4, respectively, while vitamin E (ng/ml) levels were 4.13±1.2, 6.4±1.3 ,3.15±1.1, 4.17±1.3, respectively, and the p-value was < 0.05 when comparing between all groups. TES levels (pg/ml) were 13.40±3.9, 16.04±2.6, 17.18±3.5, 11.17±2.7 in study groups and the p-value also","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"8 1","pages":"347-352"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86539352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Compulsory Licensing in the Context of the Covid-19 Coronavirus Pandemic","authors":"N. Serohina, O. Pikhurets, S. Iasechko, E. Yevlakhova, S. Lytvyn, I. Miroshnykov","doi":"10.31838/SRP.2021.1.53","DOIUrl":"https://doi.org/10.31838/SRP.2021.1.53","url":null,"abstract":"The article reveals the features and legal grounds for the application of the mechanism of restriction of patent rights through compulsory licensing of inventions. The analysis of the legislation on the regulation of these relations is carried out. The EU experience in the use of compulsory licensing is analyzed and prospects for Ukraine are considered. Theoretical positions on the subject of research are analyzed. It is substantiated that in emergency situations the state should defend the public interests to the detriment of the interests of the patent owner and may apply a compulsory license. Compulsory licensing is a common practice and an important legal institution. The conditions and features of granting a compulsory license for objects of patent law in accordance with the provisions of Ukrainian legislation are revealed. The terms of the compulsory license are not based on the mutual consent of the licensor and the licensee but are determined by the competent state body. The correlation of the Ukrainian legislation with the international obligations of Ukraine is investigated. Analysis of foreign sources shows that compulsory licensing is one of the effective mechanisms for reaching a compromise between the public interests and the patent owner. The paper confirms the expediency of shifting the balance of interests from the patent owner to society in the context of the COVID-19 pandemic. Recommendations for improving Ukrainian legislation are provided.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"24 1","pages":"334-342"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87450600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features Of The Formation Of Single-Species And Heterogeneous Agrocenoses Of Medick And Perennial Meadow-Grasses In Field Forage Production","authors":"N. Saoudi","doi":"10.31838/SRP.2021.3.68","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.68","url":null,"abstract":"The relevance of research is due to the need to improve individual elements of agrotechnology for medick and perennial meadow-grasses cultivation depending on the background of mineral nutrition, and for the creation of highly productive herbage in the gray forest soils of the southwestern part of the Central region of the Russian Federation. Perennial legumes in single-species and heterogeneous crops are the main components in solving the problem of vegetable protein in the production of the highest quality feed. The methodology of field experiments is based on the principle of intensification and biologization of agriculture. The research aims at developing elements of agricultural technologies for the cultivation of perennial grasses in single-species and heterogeneous crops and at improving the biochemical composition of forages, depending on both the species composition of the grass mixture and the effect of the background of mineral fertilizers on the yield in single-species and heterogeneous field agrocenoses. The research methods were field, laboratory, and statistical. Field studies were carried out on the experimental field of Bryansk State Agrarian University using a modern assortment of medick and perennial meadow-grasses on various backgrounds of mineral fertilizers. In the grass mixtures, the legume component varied from 40 to 50%. Sowing was carried out under the cover of one-year-old Westerwolds ryegrass (Lolium multiflorum Lam. var. westerwoldicum Wittm). Medick (Medicago varia Mart.) was used as the legume component. Meadow-grasses are represented by timothy (Phleum pratense L.), meadow fescue (Festuca pratensis Huds.), cat grass (Dactylis glomerata L.), and awnless brome (Bromus inermis). The formation of the yield of green mass and dry matter of medick and perennial meadow-grasses mixtures is justified by the background of mineral nutrition and the species composition of cultivated grass mixtures. On average, over the years of field experiments, the maximum yield (45.32 t/ha) of green mass and of dry matter (11.33 t/ha) was obtained in the variant of medick-fescue grass mixture against the background of prolonged action of Borofoska in combination with annual nitrogen fertilization at the dose N30. Under the influence of mineral fertilizers, an improvement in the biochemical composition of dry matter of heterogeneous crops of legume-perennial meadow-grasses was noted. The highest indices of nutrients were found in the forage mass of the medick-timothy grass mixture","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"45 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85468984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Complex Effect Of Retinyl Acetate And Zeolite On The Resistance Of Rabbits With Aflatoxicosis","authors":"A. Mukharlyamova, A. Tremasova, Aigul G. Mukhammetshina Oksana V. Shlyamina, Alsu R. Makaeva, S. A. Tanaseva, A. M. Sayfutdinov, I. Fitsev, A. Likhacheva, E. Rakhmetova, S. L. Mokhtarova, M. S. Khakimov","doi":"10.31838/SRP.2021.3.40","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.40","url":null,"abstract":"The article presents the results of studying the effect of a combination of zeolite from the Tatar-Shatrashansky deposit of the Republic of Tatarstan and retinyl acetate in rabbit aflatoxicosis on the indicators of natural resistance of animals. The duration of the experiment was 55 days. Animals of the first group received the main diet, of the second group received a toxic diet, animals of the third group were additionally injected retinyl acetate with a toxic diet at a dose of 1500 IU per individual, the rabbits of the fourth group, in addition to the toxic diet, received retinyl acetate at a dose of 1500 IU per individual and zeolite at a dose of 2% of the diet. Studies showed, that the complex use of retinyl acetate and zeolite is highly effective in case of aflatoxicosis, contributing to the normalization of clinical, biochemical indicators and non-specific resistance factors.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"1 1","pages":"251-253"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82970543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Of Area Under The Curve Method For The Spectrophotometric Determination Of Betamethasone Sodium Phosphate In Its Pure And Pharmaceutical Forms","authors":"Khalaf F. Alsamarrai, Harith Jameel Mahdi Alsamarraie, M. A. Al-Abbasi","doi":"10.31838/SRP.2021.1.40","DOIUrl":"https://doi.org/10.31838/SRP.2021.1.40","url":null,"abstract":"A new, fast, accurate, economic, sensitive spectrophotometric method for the determination of Betamethasone (BSP) was developed. The method includes the use of the area under the curve (AUC) of the BMT UV-spectrum in methanol. This method was very suitable to the determination of BSP because it gave good linearity which up to 10-100 µg/ml, good accuracy and precision, through Rec% values which were ranged between 98.40914-101.40864% and RSD% values were ranged between 0.05507-0.97609%, LOD was 0.029701 µg/ml and LOQ was 0.098013 µg/ml. The method successfully applied to the determination of BSP in pure and trading forms.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"79 1","pages":"254-258"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82101875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Mucinous Cystadenoma of Pancreas with Honeycombing Appearance","authors":"Awais Jamil, Atique ur-Rehman, Usama Shahid, S. Hussain","doi":"10.31838/SRP.2021.5.7","DOIUrl":"https://doi.org/10.31838/SRP.2021.5.7","url":null,"abstract":"Introduction: Large quality of imaging examination helps in the discovery of Cystic Pancreatic Lesions (CPLs). Objectives: The main objectives of the study is to eval\u0002uate the mucinous cystadenoma of pancreas with hon\u0002eycombing appearance. Methodology: This prospective study was conducted in Bahawal Victoria Hospital, Bahawalpur during 2019 to 2020. All the cases of cystic pancreatic lesions were observed by Ultrasound and contrast-enhanced CT and contrast-enhanced MRI.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"20 1","pages":"190-192"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82657356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric And Comparative Study Of Nutrient Foramina Of Femur And Humerus Bones And Its Clinical Importance In Egyptian Population","authors":"E. Ali","doi":"10.31838/SRP.2021.3.23","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.23","url":null,"abstract":"Background : knowledge with respect to nutrient foramina of bones is helpful in surgeries, for example, microvascular bone exchange to safeguard the dissemination. In any case, there is not many information on Morphometric investigates of the supplement foramina of femur and humerus in Egyptians. Subjects and methods : Between June 2019 and September 2020, we prospectively assess morphology of nutrient foramina included 350 adult long limb bones of femur and humerus Department of Anatomy in Al-Azhar University . the age and gender of which were not determined of Egyptian subjects. The bones were examined for the number, location and direction of the nutrient foramina. Aim of the work : To investigate the morphology of nutrient foramina of femur and humerus regarding to their numbers and localizations and to determine their foraminal index to provide detailed data on such features. Results : The foramina were most determined in anteromedial aspect 61% of cases on the shaft of bone in the humerus , its foramial indices were 32.1 – 68.7 % and the most of study (84%) had one nutrient foramen. In femur, we founded that the range of foraminal indices of bone 26.1 – 68 % , mainly sample (88% ) located in the middle third of the bone and (30%) had one nutrient foramen, (60%) had two nutrient foramina and only (10%) had three nutrient foramina. 56.1% nutrient foramina were located in between upper and middle 1/3rd of the Femur,,18.7% nutrient foramina were located in between middle and lower 1/3rd of the Femur ,, 23% nutrient foramina were located in middle half of the length of the Femur. Foraminal Index (FI): (Distance of nutrient foramen / Total length) ×100 Conclusion: The anatomical information of the nutrient foramen of the long bones of limb as femur and humerus is important for orthopaedic surgeons during surgical operations of bones.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":"41 1","pages":"130-135"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84969879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}