{"title":"Surgical Site Infections in Indigenous Populations of the United States and Canada: A Scoping Review.","authors":"Fabrizio Darby, Shaan Bhandarkar, Kamryn Butler, Arusha Basani, Alexandria Brackett, Vanita Ahuja, Margarita Elloso","doi":"10.1177/10962964261427348","DOIUrl":"10.1177/10962964261427348","url":null,"abstract":"<p><strong>Background: </strong>Several studies have highlighted higher rates of adverse outcomes such as superficial surgical site infection (SSI) in Indigenous populations. However, there is a paucity of literature amalgamating reports of SSI in these populations compared with other ethnic and racial groups. The aim of this review is to highlight the incidence of SSI in Indigenous populations in the United States and Canada compared with non-Indigenous patients.</p><p><strong>Methods: </strong>Based upon systematic assessment of relevant articles found in Scopus, PubMed, and PubMed Central, a state-of-the-art review was conducted. Studies in English that were cohort, cross-sectional, case-control, or randomized controlled studies on human beings of all ages and genders were included. Studies that were reviews, case series, case reports, editorials, letters to editors, animal studies, or studies that did not examine SSI as a direct outcome of surgical procedure were excluded.</p><p><strong>Results: </strong>We retrieved 1,718 articles, 9 of which were included for review. The most reported adverse surgical infection was superficial SSI. Five studies reported statistically significant increased risk of superficial SSI in Indigenous populations compared with White patients. Increased rates of deep incisional SSI for Indigenous populations compared with White patients were statistically significant in two of three studies looking at this outcome. As it relates to organ-space SSI, two studies reported statistically significant increases for Indigenous patients of the three studies reporting this parameter.</p><p><strong>Conclusion: </strong>There are statistically significant differences in the incidence of SSI for Indigenous patients, particularly when compared with their White counterparts.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"503-509"},"PeriodicalIF":1.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdullatif Alfehaid, Abdullah M Alharran, Saud Jaber Almarri, Yousef M Alajmi, Fahad A Alsaid, Sara Almutawtah, Salel M Sanaa, Monerah Falah Alajmi
{"title":"Antibiotic Versus Saline Irrigation During Open Appendectomy: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomized Controlled Trials.","authors":"Abdullatif Alfehaid, Abdullah M Alharran, Saud Jaber Almarri, Yousef M Alajmi, Fahad A Alsaid, Sara Almutawtah, Salel M Sanaa, Monerah Falah Alajmi","doi":"10.1177/10962964261484813","DOIUrl":"https://doi.org/10.1177/10962964261484813","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infection (SSI) is a common complication after open appendectomy. The effectiveness of intra-operative antibiotic irrigation compared with saline irrigation remains uncertain. To evaluate the efficacy and safety of antibiotic irrigation versus saline irrigation during open appendectomy.</p><p><strong>Methods: </strong>We conducted a systematic review and random-effects meta-analysis of randomized controlled trials comparing antibiotic irrigation with saline irrigation in patients undergoing open appendectomy. The literature search identified 40 records; after duplicate removal and title/abstract screening, 15 articles underwent full-text review, and five randomized controlled trials (RCTs) were included. Risk of bias was assessed using the ROB-2 tool.</p><p><strong>Results: </strong>Five RCTs involving 1,080 patients were included (533 antibiotic irrigation; 547 saline), conducted in Saudi Arabia, Egypt, Iran, Iraq, and Nepal. The weighted mean age was 28.20 years, and most participants were male (54.4% vs. 57.5% in intervention and control groups). The mean follow-up was 1.1 months. All trials were rated low risk of bias. SSI occurred in 4.8% (26/533) of patients receiving antibiotic irrigation versus 8.9% (49/547) receiving saline. Antibiotic irrigation significantly reduced SSI risk (RR 0.60, 95% CI: 0.36 to 0.99; p = 0.05) with minimal heterogeneity (<i>I<sup>2</sup> =</i> 6.87%). Leave-one-out analyses suggested fragility, with significance not consistently maintained when individual studies were omitted. Trial sequential analysis crossed the conventional boundary but not the monitoring boundary, and the required information size was not reached, indicating inconclusive evidence. Doi plot analysis showed minor asymmetry (LFK index -1.90). No significant differences were observed for abdominal abscess, post-operative ileus, length of stay, or operative duration.</p><p><strong>Conclusions: </strong>Antibiotic irrigation may reduce SSI after open appendectomy, but the evidence is fragile and remains insufficient by TSA. Future research should focus on minimally invasive appendectomy, with open-surgery studies reserved for settings where it remains common.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"10962964261484813"},"PeriodicalIF":1.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extent-Guided Staged Management of Localized Late-Onset MSSA Sternal Infection after Bilateral Lung Transplantation: A Case Report.","authors":"Tomohiro Baba, Shin Tanaka, Haruchika Yamamoto, Kumi Nakajima, Hidejiro Torigoe, Ken Suzawa, Kazuhiko Shien, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Shinichi Toyooka","doi":"10.1177/10962964261485030","DOIUrl":"https://doi.org/10.1177/10962964261485030","url":null,"abstract":"<p><strong>Background: </strong>Sternal infection after lung transplantation is uncommon but life-threatening; late-onset cases may be difficult to diagnose when signs are subtle.</p><p><strong>Case: </strong>A 38-year-old female developed methicillin-susceptible <i>Staphylococcus aureus</i> sternal infection with bacteremia 7 months after bilateral lung transplantation. Computed tomography (CT) showed a localized abscess around the sternal wires.</p><p><strong>Management: </strong>CT and intraoperative findings confirmed that infection was confined to extrathoracic peri-sternal tissues without communication with the thoracic cavity. This guided debridement, drainage, wire removal, antimicrobial therapy, and negative-pressure wound therapy (NPWT) with instillation and dwell time followed by standard NPWT.</p><p><strong>Outcome: </strong>After infection control and adequate granulation, delayed primary closure was performed 60 days after debridement without flap reconstruction. She was discharged on day 77, without recurrence, 8 months after closure.</p><p><strong>Conclusions: </strong>Careful assessment of infection extent may help identify patients with localized infection suitable for staged management, permitting delayed primary closure without flap reconstruction.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"10962964261485030"},"PeriodicalIF":1.7,"publicationDate":"2026-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexis A Heilman, Wihan Du Plessis, Edward P Dominguez, John D Leff
{"title":"Two Rare Cases of Mesh Infection Due to <i>Mycobacterium abscessus</i> Following Laparoscopic Inguinal Hernia Repair.","authors":"Alexis A Heilman, Wihan Du Plessis, Edward P Dominguez, John D Leff","doi":"10.1177/10962964261485064","DOIUrl":"https://doi.org/10.1177/10962964261485064","url":null,"abstract":"<p><strong>Background: </strong>Mesh infections after laparoscopic inguinal hernia repair are rare, particularly those caused by <i>Mycobacterium abscessus</i>, a multi-drug-resistant nontuberculous mycobacterium.</p><p><strong>Case presentation: </strong>We describe two cases of <i>M. abscessus</i> infection following total extraperitoneal inguinal hernia repairs. Both patients developed delayed groin pain and fluid collections. Cultures confirmed <i>M. abscessus</i>, requiring mesh explanation and prolonged multi-drug antibiotic therapy. Despite complications, both achieved infection resolution after approximately 12 months.</p><p><strong>Discussion: </strong>Investigation suggested contamination of laparoscopic instrument sheaths as the infection source, prompting changes in sterilization protocols. The pathogen's biofilm formation and resistance to sterilization contributed to persistence.</p><p><strong>Conclusion: </strong>Early recognition, mesh removal, and multi-disciplinary care are essential for successful management of <i>M. abscessus</i> mesh infections. Strict adherence to sterilization protocols is critical in preventing such rare but serious complications.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"10962964261485064"},"PeriodicalIF":1.7,"publicationDate":"2026-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgical infectionsPub Date : 2026-08-01Epub Date: 2026-02-03DOI: 10.1177/10962964261419644
Jongmin Won, Seong Jun Ryu, Seung Yong Song
{"title":"Re-sterilization Prior to Implant Insertion in Prosthetic Breast Reconstruction: Is It Necessary?","authors":"Jongmin Won, Seong Jun Ryu, Seung Yong Song","doi":"10.1177/10962964261419644","DOIUrl":"10.1177/10962964261419644","url":null,"abstract":"<p><strong>Purpose: </strong>Breast operations have a surgical site infection rate of <1.5%, a figure that increases to 3% after implant-based reconstructions. We aimed to assess whether contamination occurred before implant insertion and could be related to post-operative infections.</p><p><strong>Patients and methods: </strong>The reconstruction team prepared the surgical field using a betadine solution and standard draping. After the surgical procedures, the antiseptic was re-applied around the incision, the surgical field re-draped, and the gloves changed before implant insertion. Immediately before the betadine application and re-draping, swab cultures were collected from the peri-areolar regions and margins of the exposed field. Any signs of infection were checked during the 2-year follow-up.</p><p><strong>Results: </strong>A total of 164 cases were included; of these 13 showed positive swab cultures (12 of <i>Staphylococcus epidermidis</i>, and one of <i>Bacillus</i> species). Among them, only one patient developed a post-operative infection necessitating the insertion of a Hemovac drain at 42 days after a surgical procedure. Among the 151 patients with negative swab culture results, 10 patients received a diagnosis of post-operative infections; follow-up cultures primarily identified <i>S. aureus</i> (three methicillin-sensitive cases, four methicillin-resistant cases), whereas two were culture-negative.</p><p><strong>Conclusion: </strong>Residual contamination may persist despite the initial surgical site sterilization. The re-application of antiseptics and re-draping immediately before implant insertion may help reduce post-operative infections and should be considered an adjunct to comprehensive peri-operative protocols. Some infections may be more closely related to post-operative management than pre-implant field contamination, underscoring the need for meticulous post-operative care. Definitive causal relationships should be tested using rigorously designed and adequately powered studies.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"422-429"},"PeriodicalIF":1.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146114380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Late Recurrence of Empyema More Than a Decade after Window Thoracostomy: Secondary <i>Aspergillus</i> Infection Superimposed on Prior MRSA Empyema, Successfully Managed by Stepwise Surgical and Endobronchial Definitive Closure.","authors":"Kaoru Kondo, Shin Tanaka, Haruchika Yamamoto, Kumi Nakashima, Hidejiro Torigoe, Ken Suzawa, Kazuhiko Shien, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Shinichi Toyooka","doi":"10.1177/10962964251407580","DOIUrl":"10.1177/10962964251407580","url":null,"abstract":"<p><strong>Background: </strong>Fungal empyema is uncommon and has worse short-term outcomes than bacterial disease, particularly when a bronchopleural fistula (BPF) sustains contamination.</p><p><strong>Case: </strong>A previously healthy male developed BPF and methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) empyema after right upper lobectomy at age 17, managed by open-window thoracostomy (OWT). An apical residual space persisted and formed a fungus-ball-like nodule. At age 30, he re-presented with fever and nodule growth, with elevated <i>Aspergillus</i> IgG; voriconazole was started.</p><p><strong>Management: </strong>Computed tomography-guided catheter placement and re-OWT exposed air leaks and recurrent MRSA. Staged fistula control with endobronchial Watanabe spigots, <i>n</i>-butyl-2-cyanoacrylate, and cavity-side suturing achieved cessation.</p><p><strong>Outcome: </strong>After irrigation, sterilized cultures, negative-pressure therapy preceded latissimus dorsi flap obliteration. He was discharged on postoperative day 149 without recurrence.</p><p><strong>Conclusions: </strong>A stepwise plan-source control, fistula control, sterilization, and obliteration-can achieve durable cure in mixed <i>Aspergillus</i>-MRSA empyema with BPF after prior OWT.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"449-452"},"PeriodicalIF":1.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145858061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}