Surgical infections最新文献

{"title":"Beyond the p-Value: Has Statistical Reporting Evolved in Surgical Infections?","authors":"Matthew Kwasnik, Andrew H Stephen, Daithi S Heffernan","doi":"10.1177/10962964261493845","DOIUrl":"https://doi.org/10.1177/10962964261493845","url":null,"abstract":"<p><strong>Background: </strong>Appropriate statistical methodology and transparent reporting are essential for the validity and reproducibility of research. Despite landmark guidance from the American Statistical Association (ASA), inadequate statistical reporting remains common in surgical literature. We examined whether the nature and quality of statistical reporting in the <i>Surgical Infections</i> journal changed between 2015 and 2023.</p><p><strong>Methods: </strong>A retrospective review of original research articles published in <i>Surgical Infections</i> in 2015 compared to 2023 was performed. The methods and results sections of included articles were reviewed for: reporting of <i>a priori</i> significance level (α), power calculation performance and methodology, p-value reporting modalities, confidence interval use, and claims of statistical significance. Dichotomous variables were compared using Fisher exact test, continuous variables by Student's t-test, and variances by F-statistic.</p><p><strong>Results: </strong>A total of 102 (2015) and 86 (2023) articles met inclusion criteria. Power calculations were reported in only 11.7% of articles overall, with no significant change between years (p = 0.25). Reporting of α decreased from 79.4% to 67.4% (p = 0.07), with near-uniform convergence to p < 0.05 in 2023 (86% vs. 98%; p = 0.01). The number of unique p-value reporting modalities increased between years, with one 2023 article employing 15 distinct modalities. Confidence-interval reporting was unchanged (58.9% vs. 61.6%; p = 0.6). Claims of statistical significance decreased from 92.2% to 79.1% of articles (p = 0.01).</p><p><strong>Conclusions: </strong>Statistical reporting in <i>Surgical Infections</i> showed little improvement from 2015 to 2023 despite evolving national guidance. Fewer authors claimed significance, and the journal demonstrated no requirement for significance for publication. We recommend standardized statistical-reporting guidelines.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"10962964261493845"},"PeriodicalIF":1.7,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal Pelvic Urine Density for Early Prediction of Post-Decompression Systemic Inflammatory Response in Stone-Related Obstruction.","authors":"Ali Ayten, Oguzhan Cura, Mert Kahraman, Ferhat Berker, Mucahit Gelmis, Burak Arslan","doi":"10.1177/10962964261440869","DOIUrl":"10.1177/10962964261440869","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted to evaluate the prognostic value of renal pelvic urine density (RPUD) measured by computed tomography (CT) in predicting systemic inflammatory response syndrome (SIRS) after decompression in patients with non-infectious obstructive uropathy associated with stones.</p><p><strong>Patients and methods: </strong>Patients who underwent emergency decompression due to non-infectious obstructive uropathy caused by urinary stones between January 2018 and July 2025 were retrospectively analyzed. Cases with clinical, laboratory, or radiological findings of infection were excluded from the study. Demographic characteristics, stone characteristics, degree of hydronephrosis, RPUD, and perioperative parameters were recorded. Patients were divided into SIRS (+) and SIRS (-) groups on the basis of postoperative clinical findings. Independent predictors of SIRS were determined using multi-variable logistic regression, and the diagnostic performance of RPUD was evaluated using receiver operating characteristic (ROC) analysis.</p><p><strong>Results: </strong>A total of 247 patients were included in the study, and 36 (14.6%) developed SIRS after decompression. RPUD values were significantly higher in SIRS (+) patients (12.5 vs. 9.4 HU, p < 0.001). Multi-variable analysis identified RPUD as an independent predictor of SIRS (odds ratios [OR] = 2.061, 95% CI: 1.586-2.679, p < 0.001). ROC analysis showed that an RPUD cutoff value of 10.5 HU predicted SIRS development with 77.8% sensitivity and 74.9% specificity, area under the curve (AUC) = 0.830.</p><p><strong>Conclusion: </strong>RPUD is a strong and independent prognostic marker for the early prediction of SIRS after decompression in non-infectious obstructive uropathy associated with stones.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"560-565"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147628760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergency Cesarean Section Pre-operative Antibiotic Agent Prophylaxis-Opportunities for Improvement.","authors":"Gabriela Cortese, Stefka Fabbri, Daniel Dante Yeh, Robyn Bronshtein, Heather Young, Alex Kaizer","doi":"10.1177/10962964261438107","DOIUrl":"10.1177/10962964261438107","url":null,"abstract":"<p><strong>Background: </strong>Surgical Care Improvement Project (SCIP) recommends prophylactic antibiotic agents (abx) within 60 min before incision. This quality improvement study assessed SCIP compliance in emergent cesarean sections (CSs) to identify opportunities for improvement.</p><p><strong>Methods: </strong>This retrospective study included patients undergoing emergent CSs at our institution between May 2016 and December 2023. Maternal demographic, obstetric, medical, and labor outcomes were abstracted. The primary outcome was the incidence of timely (within 60 min of incision) administration of abx. Secondary outcomes included maternal intensive care unit (ICU) admission, hospital length of stay (LOS), loss to follow-up, surgical site infection (SSI), and 30-day outcomes. Logistic regression analyses were performed to identify predictors of SCIP compliance.</p><p><strong>Results: </strong>A total of 876 patients were included in the study. The most common indication for CSs was non-reassuring fetal status, and the most common form of anesthesia was epidural. Abx were administered in 98% of cases, but only 73% were SCIP compliant. Chlorhexidine-alcohol was most commonly used for abdominal skin preparation. There were significant differences between the SCIP Not Compliant versus Compliant group, but multiple logistic regression identified only American Society of Anesthesiologists (ASA) Class 3 (OR: 0.69 95% CI: 0.49-0.97, p = 0.034), ASA Classes 4/5 (OR: 0.22 95% CI: 0.04-0.96, p = 0.047), and prolapsed cord as indication for CSs (OR: 0.22 95% CI: 0.10-0.49, p < 0.001) as predictors of SCIP Not Compliant. Maternal morbidity was low, with only 2% ICU admission and median hospital LOS 4 days. Only (5%) were lost to follow-up. SSI rate was low (4%).</p><p><strong>Conclusion: </strong>We identified timeliness of pre-operative abx administration, abdominal skin preparation agent, and post-discharge follow-up as opportunities for improvement. SCIP non-compliance was significantly associated with emergent cesarean indication and higher ASA class. Post-operative SSI rates were low, though bias may be present because of the high loss-to-follow-up.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"544-551"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Real-World Analysis of Hydrocortisone and Fludrocortisone Prescribing in Surgical Patients with Septic Shock.","authors":"Arnav Mahajan, Nick Beattie, Nilam Patel, Andrew Tran, Vanessa P Ho, Justin E Dvorak","doi":"10.1177/10962964261437315","DOIUrl":"10.1177/10962964261437315","url":null,"abstract":"<p><strong>Background: </strong>Corticosteroid use in septic shock remains controversial, with trials showing conflicting results. Most studies have been conducted in mixed medical-surgical populations, limiting generalizability to surgical patients who face unique risks. We examined how timing of steroid administration affects outcomes in surgical intensive care unit patients with septic shock.</p><p><strong>Methods: </strong>In this retrospective cohort study, we analyzed data from 13,512 surgical patients with septic shock using the TriNetX platform. Patients were categorized into four cohorts: no steroids (n = 8,180), any steroid therapy (n = 5,332), early therapy (≤24 h, n = 2,911), and late therapy (>24 h, n = 2,421). We conducted propensity-matched analyses examining 90-day mortality, infectious complications, and surgical complications.</p><p><strong>Results: </strong>Early steroid administration was associated with lower 90-day mortality compared with no steroids (31.5% vs. 33.3%; hazard ratio [HR]: 0.74; 95% confidence interval [CI]: 0.62-0.88; p = 0.006), whereas late administration correlated with higher mortality (34.1% vs. 27.1%; HR: 1.26; 95% CI: 1.11-1.43; p < 0.001). Steroids were associated with lower rates of surgical site infections (relative risk [RR]: 0.63; p = 0.032) and wound dehiscence (RR: 0.73; p = 0.019), but higher rates of pneumonia (RR: 1.22; p = 0.003), myopathy (RR: 2.25; p < 0.001), and bowel ischemia (RR: 2.29; p = 0.008).</p><p><strong>Conclusions: </strong>In surgical ICU patients with septic shock, the timing of steroid administration impacts outcomes. Early administration was associated with reduced mortality, whereas late administration correlated with increased mortality. Steroids demonstrated a complex profile of beneficial and adverse effects on post-surgical complications. These findings highlight the importance of timing of therapy in surgical septic shock and may help explain conflicting results from previous trials in mixed populations.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"529-537"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted Antimicrobial Agent Prophylaxis Fails to Reduce Peristomal Infections by Multi-Drug-Resistant Bacteria Following Percutaneous Endoscopic Gastrostomy: A Prospective Cohort Study.","authors":"Blanca Marzo-Escartín, Miguel Villamarín-Melio, Ester Márquez-Algaba, Fiorella Ximena Palmas-Candía, Alba Zabalegui, Rosa Burgos-Peláez, Mayli Lung-Suárez, Joan Dot, Mercedes Pérez-Lafuente, Óscar Len","doi":"10.1177/10962964261438723","DOIUrl":"10.1177/10962964261438723","url":null,"abstract":"<p><strong>Background: </strong>Peristomal infection (PI) is the most frequent complication following percutaneous gastrostomy, and the increase of multi-drug-resistant (MDR) bacteria poses a therapeutic challenge. We evaluated whether targeted antimicrobial agent prophylaxis (TAP), on the basis of pre-procedure rectal screening, reduces the incidence of MDR PIs compared with standard prophylaxis.</p><p><strong>Methods: </strong>We conducted a single-center, single-arm, open-label trial, comparing a prospective cohort (July 2021-July 2022) receiving TAP based on MDR screening results with a retrospective cohort (June 2020-June 2021) that received standard prophylaxis. A total of 118 patients were included, 60 in the intervention group and 58 in the historical cohort. TAP patients underwent a pre-procedure screening tactic, using nasal, axillary, inguinal, pharyngo-tonsillar, and rectal swabs. Patients with positive cultures received prophylaxis with an antibiotic agent active against the isolated bacteria, along with coverage for methicillin-sensitive <i>Staphylococcus aureus</i>. Patients with negative cultures received standard prophylaxis with amoxicillin-clavulanate. Both regimens were administered as a single dose one hour before the procedure.</p><p><strong>Results: </strong>MDR colonization was detected in 36.4% of screened patients. The 30-day PI incidence was comparable in both cohorts [20.7% (12/58) in the historical cohort vs. 16.7% (10/60) in the intervention group; p = 0.64]. Among TAP patients who developed PI, 7/10 had negative MDR screening, 3/10 had infections caused by pathogens different from those identified in screening, and 2/10 developed infections with the same MDR bacteria despite appropriate prophylaxis.</p><p><strong>Conclusions: </strong>In patients undergoing percutaneous gastrostomy, TAP based on MDR colonization status did not reduce the incidence of PIs or MDR etiology compared with standard prophylaxis. Our findings question the role of colonization-guided prophylaxis in percutaneous gastrostomy and underscore the need for alternative preventive tactics in surgical site infection control.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"552-559"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147781722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diverticulitis in Pregnancy Is Associated with High Complication Rates.","authors":"Dayle Colpitts, Allyson M Hynes, Jarrett Santorelli, Alan Smith, Jessica L Weaver","doi":"10.1177/10962964261441488","DOIUrl":"10.1177/10962964261441488","url":null,"abstract":"<p><strong>Background: </strong>National trends toward earlier onset of diverticulitis combined with more advanced maternal age may converge, making diverticulitis an increasingly important etiology of obstetric abdominal infection. However, there is little data on this topic, and no specific guidelines on how to treat pregnant patients with the disease. The purpose of this study was to identify the frequency of hospitalization for diverticulitis in pregnant patients and the common complications associated with this disease process.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using the National Readmissions Database (NRD) to evaluate maternal and fetal complications among pregnant patients diagnosed with diverticulitis. The NRD was queried for all visits in the first 3 quarters of each year, 2016-2019, that included a patient with an International Classification of Diseases-10 code for diverticulitis and pregnancy. These entries were then further investigated for demographics, gestational age, rates of intervention, readmissions, and maternal and fetal complications.</p><p><strong>Results: </strong>A total of 470 patients were identified with a diagnosis of diverticulitis and pregnancy. Most patients (n = 340, 72.3%) were in the third trimester of pregnancy at presentation. 160/470 (34.0%) of admissions led to fetal delivery within 48 h. Of these, 3.8% of patients (n = 18) had complicated diverticulitis on index admission. The 90-day readmission rate for perforation or abscess was 1.3%. There were no reported maternal deaths. The overall rate of maternal complications was 41.3% and fetal complications was 41%, including a 1.9% rate of fetal loss.</p><p><strong>Conclusions: </strong>Diverticulitis is associated with significant rates of maternal and fetal complications when it occurs during pregnancy. Further investigation is warranted to better define the outcomes and guide best practices in this population.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"538-543"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decreased Maximum Amplitude as a Potential Parameter to Predict the Likelihood of Mortality in Complicated Intra-Abdominal Infection Patients with Thrombocytopenia.","authors":"Tao Tian, Danhua Yao, Yuhua Huang, Pengfei Wang, Yousheng Li","doi":"10.1177/10962964261441210","DOIUrl":"10.1177/10962964261441210","url":null,"abstract":"<p><strong>Background: </strong>Thrombocytopenia is one of the common serious complications among complicated intra-abdominal infection (cIAI) patients. Maximum amplitude (MA), a thromboelastography parameter, represents fibrinogen levels, platelet count, and platelet function. Our study aimed to elucidate the association between decreased MA and mortality among cIAI patients with thrombocytopenia.</p><p><strong>Methods: </strong>cIAI patients with thrombocytopenia were enrolled-in. Clinical data and various laboratory values were collected. Uni-variable analysis and multi-variable logistic regression were used to evaluate the correlation between decreased MA and mortality. The area under the curve (AUC) was calculated to evaluate the predictive performance.</p><p><strong>Results: </strong>A total of 58 cIAI patients with thrombocytopenia were included. According to the uni-variable analysis, decreased MA was significantly associated with patient mortality (odds ratio [OR]: 15.41, 95% confidence interval [CI]: 4.03-58.91; p < 0.001). In the multi-variable analysis model 1, which was adjusted for age and gender, decreased MA remained significantly associated with increased patient mortality (OR: 10.96, 95% CI: 2.44-49.20; p = 0.002). After adjusting for age, gender, platelet count, acute physiology and chronic health evaluation II score, and sequential organ failure assessment score (model 2), decreased MA was also a risk factor for patient mortality (OR: 12.66, 95% CI: 1.81-88.78; p = 0.011). MA levels were significantly lower in non-survivors than in survivors (all p < 0.05). The AUC of MA for predicting mortality was 0.72 (95% CI: 0.58-0.87; p = 0.0036).</p><p><strong>Conclusion: </strong>Decreased MA may be a potential parameter to help predict the likelihood of mortality in cIAI patients with thrombocytopenia.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"566-571"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polymicrobial Infection Is Associated with Failure of DAIR in Acute Hip Periprosthetic Joint Infection.","authors":"José María Lamo-Espinosa, Álvaro Suárez-López Del Amo, Francisco Carmona-Torre, Telmo García-Orueta, Mikel San-Julián, José Luis Del Pozo","doi":"10.1177/10962964261444963","DOIUrl":"10.1177/10962964261444963","url":null,"abstract":"<p><strong>Background: </strong>Debridement, antibiotics, and implant retention (DAIR) is a commonly used tactic for the management of acute periprosthetic joint infection (PJI) following total hip arthroplasty. However, patient selection remains challenging, and predictors of treatment failure are not clearly defined.</p><p><strong>Patients and methods: </strong>A retrospective cohort study was conducted in a single center including 48 patients treated with DAIR for acute hip PJI between 2000 and 2019. Clinical characteristics, comorbidities, microbiological findings, and perioperative variables were analyzed. Treatment failure was defined as the need for implant removal or exchange, resection arthroplasty, or chronic suppressive antibiotic therapy. Multivariable logistic regression and receiver operating characteristic (ROC) curve analysis were performed to explore factors associated with DAIR failure.</p><p><strong>Results: </strong>The mean age was 69.3 years. At a mean follow-up of 23.7 months, infection control was achieved in 83.3% of cases. Polymicrobial infection was significantly associated with treatment failure compared with monomicrobial infection (57.1% vs. 87.5%, p = 0.049). An exploratory predictive model demonstrated acceptable to good discriminatory performance in this exploratory cohort for DAIR outcome (area under the curve = 0.87).</p><p><strong>Conclusions: </strong>DAIR is an effective treatment option for selected patients with acute hip PJI. Polymicrobial infection was associated with treatment failure and should prompt careful consideration of alternative surgical strategies. Exploratory risk stratification models may assist in preoperative decision-making; however, validation in larger cohorts is required.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"579-584"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147729942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Letter: Cryptococcus</i> Infection of the Acromion: A Rare Presentation.","authors":"Bo Sun, Jiaqi Deng, Rong Kuang, Jing Zhou","doi":"10.1177/10962964261440865","DOIUrl":"10.1177/10962964261440865","url":null,"abstract":"","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"585-586"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147628725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Risk Factors and Construction of a Nomogram Prediction Model for Surgical Site Infection after Modified Radical Mastoidectomy.","authors":"Yuanye Li, Zhongyan Li, Dongdong Huo","doi":"10.1177/10962964261444924","DOIUrl":"10.1177/10962964261444924","url":null,"abstract":"<p><strong>Background: </strong>Modified radical mastoidectomy (MRM) is a common surgical procedure in otology. However, postoperative surgical site infection (SSI) will lengthen hospital stay, raise healthcare expenses, and even lead to the death of patients. At present, there is relatively little research on the risk factors of SSI after MRM, especially the lack of an established risk prediction model.</p><p><strong>Patients and methods: </strong>Patients who underwent MRM at Jining NO.1 People's Hospital from 2020 to 2024 were selected. Univariate analysis and multivariate logistic regression analysis were used to identify the risk factors for SSI after MRM. On the basis of these factors, a Nomogram prediction model was constructed. The predictive value of the model was evaluated by constructing receiver operating characteristic (ROC) curve, calibration curve, and decision curve.</p><p><strong>Results: </strong>A total of 278 MRM patients met the inclusion criteria, 19 (6.83%) had developed SSI, and 259 (93.17%) had not. Multivariate logistic regression analysis confirmed diabetes, hypoproteinemia, neutrophil-to-lymphocyte ratio, antibiotic prophylaxis administered 0.5-1 h preoperatively, and operative time as independent factors (all p <0.05). The prediction model demonstrated excellent discriminative ability. Area under the curve of the ROC curve was 0.856, validated by Hosmer-Lemeshow testing (χ² = 6.265, p = 0.618), calibration curve, and decision curve analysis. These findings highlight the model's robust accuracy and clinical utility in stratifying the risk of SSI after MRM.</p><p><strong>Conclusions: </strong>The Nomogram prediction model constructed based on logistic regression can effectively predict the risk of SSI after MRM, which is helpful for early clinical intervention and reducing the occurrence of nosocomial infection.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":" ","pages":"572-578"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147729917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}