Translation: The University of Toledo Journal of Medical Sciences最新文献

{"title":"Characterization of Human Colon Tissue for Harmful Algal Bloom Exposure in Cancer and Non-Cancer Patients","authors":"Bella Khatib-Shahidi, John Najjar, Anish Sharma, Sara Kazmi, Apurva Lad, Benjamin French, Bivek Timalsima, Caitlin Murphy, Julissa Vargas, Humza Bashir, David Kennedy, Steven Haller","doi":"10.46570/utjms.vol11-2023-949","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-949","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"1 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary tuberculosis infection in the setting of Interstitial Lung Disease","authors":"Safa Habib, Rebecca Asher, Salman Arif, Hend Elsaghir","doi":"10.46570/utjms.vol11-2023-850","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-850","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"288 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Salmonellosis Complicating Ofatumumab Therapy for Multiple Sclerosis","authors":"Justin Franco, Makoto Ibaraki, Basmah Khalil, Joel A. Kammeyer, Komal Masood","doi":"10.46570/utjms.vol11-2023-1000","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-1000","url":null,"abstract":"factors for recurrent NTS include young/old age, contaminated","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"330 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carfilzomib induced Alveolar Hemorrhage","authors":"Zachary Holtzapple, Andrew Campbell, Konrad Katterle, Fadi Safi","doi":"10.46570/utjms.vol11-2023-844","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-844","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"60 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure to Microcystin-LR Induces Differential Gene Regulation in Primary Human Keratinocytes","authors":"Shereen Yassine, Benjamin French, Steven Haller, David Kennedy","doi":"10.46570/utjms.vol11-2023-914","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-914","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"11 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesenteric Lymphadenopathy: a Rare Case of Rosai-Dorfman Disease","authors":"Amy Waters Waters, MD Joan Gekonde, MD Nathaniel Gilbert, MD Nezam Altorok","doi":"10.46570/utjms.vol11-2023-902","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-902","url":null,"abstract":"Introduction:  \u0000Rosai-Dorfman Disease (RDD) is rare with approximately 100 new cases annually in the United States and a mean age of 20.6 years [1]. RDD is characterized by massive lymphadenopathy and sinus histiocytosis [1].  Bilateral cervical lymphadenopathy is the typical presentation, however extra nodal sites have been noted [1].  This case discusses manifestations of a rare disease state.   \u0000Case Presentation: \u0000A 19 year old male with a history of eczema and juvenile rheumatoid arthritis presented to the emergency room with four days of diffuse abdominal pain localized to the left upper quadrant, radiation to the right lateral ribs with nausea and diarrhea.  He reported an unintentional weight loss of 30 pounds in the last three months. Physical exam revealed generalized abdominal tenderness and rebound. Computed tomography of the abdomen and pelvis (CTAP) along with routine labs were ordered.  CTAP showed retroperitoneal lymphadenopathy up to two centimeters in the short axis (figure 1) and mesenteric adenopathy with a 15 millimeter lymph node in the right lower quadrant. Histopathology reported necrotizing granulomatous lymphadenitis with benign sinus histiocytes. Referral to rheumatology was made and treatment was initiated with prednisone 20 milligrams daily with plans for repeat abdominal imaging to evaluate for reduction of adenopathy.  \u0000Discussion: \u0000RDD coexists with immunologic disease in 10% of cases.3 It has been associated with systemic lupus erythematous, idiopathic juvenile arthritis, autoimmune hemolytic anemia,24 and one case of RAS-associated autoimmune leukoproliferative disease [1]. The prognosis for RDD is indolent, 50% of patients experiencing resolution, one third with residual asymptomatic adenopathy and 17% with persistent symptomatology [2].  Our case highlights our patient’s associated history of juvenile rheumatoid arthritis now presenting with histological findings of RDD. A methodical approach to assessing patients with diffuse abdominal pain and ensured collaboration amongst different medical specialists will ensure favorable treatment outcomes.","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"73 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Fentanyl Exposure during Mechanical Ventilation: A Retrospective Study","authors":"Rachel Ko, Dan Wright, Jonathan Irvin, Anna Guo, Saira Khan, Zachary Holtzapple, A. Abrahamian, William Barnett, Brian Kaminski, Ragheb Assaly","doi":"10.46570/utjms.vol11-2023-936","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-936","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"7 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Into the unknown: Navigating orbital cellulitis to reveal retinal metastasis of a hidden primary tumor","authors":"Mohammed Abu-Rumaileh, Kashvi Patel, Fahham Asghar","doi":"10.46570/utjms.vol11-2023-874","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-874","url":null,"abstract":"Introduction \u0000This is a rare patient presentation of retinal metastasis with an unknown primary tumor. \u0000  \u0000Case Presentation \u0000A 65-year-old woman with a past medical history of left breast carcinoma stage 1 status post left mastectomy in 2014, iron deficiency anemia, anxiety, and depression presented to the emergency department with 1-2 weeks of worsening lower abdominal pain and left-sided chest pain. She also complained of right eye pain, blurry vision, and painful eye movement. Ocular examination demonstrated edema, mild proptosis, conjunctival chemosis, and conjunctival injection. Patient was started on bacitracin ointment and ceftriaxone due to concerns of orbital cellulitis. Ophthalmology was consulted, and their assessment was suggestive of bilateral metastatic neoplastic lesion in retina of both eyes, more pronounced in the right than the left eye. Left supraclavicular lymph node biopsy showed metastatic adenocarcinoma, likely of gastrointestinal or pancreaticobiliary primary. MRI brain was suspicious for calvarial metastatic disease, MRI abdomen showed multiple nodules in the liver suggesting metastases, and whole-body nuclear medicine bone scan suggested possible metastases in the hemithorax and bilateral femurs. After several goals of care discussions, the decision was made by the patient and her family to pursue comfort measures only and she was discharged home with home hospice and later passed away. \u0000  \u0000Conclusion \u0000Retinal metastasis is a rare condition due to the absence of lymphatic system in the eye (1). The most common primary tumors to metastasize to the eye are from breast (47%), lung (21%), and the gastrointestinal tract (4%) (2). In some cases, patients may have no other symptoms (1). Thus, retinal metastasis is important to include in the differential diagnosis, especially for patients with a history of treated primary cancer.","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"84 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Expression of Organic Anion Transporting Polypeptides in the Kidney","authors":"Margo Bush, James Bassett, Alexander Luna, K. Helminiak, Joshua D. Breidenbach, Benjamin French, Steven Haller, David Kennedy","doi":"10.46570/utjms.vol11-2023-892","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-892","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"14 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138970636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative Consequences of False Negative Lung Cancer Screenings","authors":"Hoda Shabpiray, Mani Khorsand Askari, Jerrin George","doi":"10.46570/utjms.vol11-2023-833","DOIUrl":"https://doi.org/10.46570/utjms.vol11-2023-833","url":null,"abstract":"","PeriodicalId":220681,"journal":{"name":"Translation: The University of Toledo Journal of Medical Sciences","volume":"36 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}