Société Internationale d’Urologie Journal最新文献_第8页

Urothelial Carcinoma Seeding at Site of Nephrostomy 肾造口部位的尿路上皮癌

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/zvxi1252

Ala'a Farkouh, M. Shahait

引用次数: 0

Management of Men With Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia During and After COVID-19 男性下尿路良性前列腺增生在2019冠状病毒病期间和之后的处理

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/jtru9739

D. Elterman, J. Baard, M. Averbeck, M. Hassouna, S. Takahashi, I. Chibuzo, A. Sebastianelli, M. Gacci

{"title":"Management of Men With Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia During and After COVID-19","authors":"D. Elterman, J. Baard, M. Averbeck, M. Hassouna, S. Takahashi, I. Chibuzo, A. Sebastianelli, M. Gacci","doi":"10.48083/jtru9739","DOIUrl":"https://doi.org/10.48083/jtru9739","url":null,"abstract":"The lower urinary tract (LUT), in particular the prostate, has been theoretically recognized as a target for SARS-CoV-2. Moreover, common pathophysiological mechanisms have been described for BPE/LUTS and COVID-19, including RAS dysregulation, androgen receptors, and MetS-related factors. These factors raise concerns about the possibility of worse urological outcomes due to BPE/LUTS progression in COVID-19 patients. The available results suggest a correlation between SARS-CoV-2 infection, exacerbation or new onset of LUTS, and semen impairment. BPE patients’ care and management have been deeply affected by COVID-19. In the midst of the pandemic, the main urological guidelines suggested postponement of BPH-related deferrable medical examinations and surgery. Telemedicine, therefore, gained attention and interest. Clinical evidence of impaired QoL or complications expedited surgical intervention. An informed consent covering the risk of COVID-19 and a negative molecular PCR within 72 hours of surgery were mandatory. A reduction in procedures under general anaesthesia was recommended. Long waiting lists accrued worldwide during the pandemic, leading to regular review of the BPE waiting lists and patients’ clinical status, encouraging the increase of minimally invasive office-based procedures, even in the post-COVID-19 era, and the improvement of telemedicine. Prospective studies are still needed to assess the course of LUTS/BPE patients after COVID-19.","PeriodicalId":21961,"journal":{"name":"Société Internationale d’Urologie Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84501370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is “Movember” an Effective Prostate Cancer Awareness Campaign Beyond the English Language? Insights From Google Trends Among Spanish Speakers “八字胡十一月”是一个有效的前列腺癌宣传活动吗?西班牙语使用者的谷歌趋势分析

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/uhsi5324

D. González-Padilla, R. España-Navarro, J. D. Subiela, Raj Kumar, L. G. Medina, J. Aumatell, J. M. De la Morena-Gallego, G. Cacciamani

{"title":"Is “Movember” an Effective Prostate Cancer Awareness Campaign Beyond the English Language? Insights From Google Trends Among Spanish Speakers","authors":"D. González-Padilla, R. España-Navarro, J. D. Subiela, Raj Kumar, L. G. Medina, J. Aumatell, J. M. De la Morena-Gallego, G. Cacciamani","doi":"10.48083/uhsi5324","DOIUrl":"https://doi.org/10.48083/uhsi5324","url":null,"abstract":"Objective To evaluate the impact of the “Movember” awareness campaign (men’s health campaign that takes place every November) on internet search trends for information online about prostate cancer and to compare the results with those for “Pinktober” (the breast cancer awareness campaign that takes place in October) in the Spanish language as an indirect measure of its effectiveness. Methods Google Trends was used to evaluate the monthly relative search volumes (RSV) of the terms “cáncer de próstata” (prostate cancer), “cáncer de mama” (breast cancer), and “Movember” from January 2009 to December 2019 both in Spain and worldwide (in the Spanish language). Breast cancer was used as a comparator of the campaign impact. Mean increase in RSV on-campaign and off-campaign was calculated and compared using the Mann-Whitney U test and Joinpoint regression analysis to assess loss or gain of interest. Results The term “cáncer de próstata” showed a statistically significant increase during the campaign months both in Spain (17.4%; P < 0.001) and worldwide (35.4%; P < 0.001). Both “cáncer de próstata” and Movember showed a decreasing trend worldwide and in Spain, while “cáncer de mama” showed an increasing trend. Conclusion The Movember campaign generates a statistically significant increase in the search trends on “cancer de próstata” (prostate cancer) during the month of November (both in Spain and worldwide); when compared with the breast cancer campaign “Pinktober” these increases are of a lesser magnitude but still significant, suggesting that the campaign is effective beyond the English language, although the interest has been decreasing throughout the years.","PeriodicalId":21961,"journal":{"name":"Société Internationale d’Urologie Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86749148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Expert Roundtable Discussion on Penile Prosthesis Infection Prevention Measures 阴茎假体感染预防措施专家圆桌讨论

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/gvcc5010

E. Chung, M. Gross, K. van Renterghem, J. Simhan

引用次数: 1

Protocol for a Pilot Study of the NODE Trial, a Prospective Multicentre Randomised Trial of Extended Pelvic Lymph Node Dissection for High-Risk Prostate Cancer NODE试验的试点研究方案，这是一项前瞻性多中心随机试验，用于扩展盆腔淋巴结清扫治疗高危前列腺癌

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/hahe3801

G. McClintock, Hadia Khanani, A. de Rosa, S. Leslie, N. Ahmadi, J. Fallot, P. Ferguson, H. Woo

{"title":"Protocol for a Pilot Study of the NODE Trial, a Prospective Multicentre Randomised Trial of Extended Pelvic Lymph Node Dissection for High-Risk Prostate Cancer","authors":"G. McClintock, Hadia Khanani, A. de Rosa, S. Leslie, N. Ahmadi, J. Fallot, P. Ferguson, H. Woo","doi":"10.48083/hahe3801","DOIUrl":"https://doi.org/10.48083/hahe3801","url":null,"abstract":"Objectives To test the hypothesis that a randomised trial of extended pelvic lymph node dissection (ePLND) can recruit at a rate acceptable for a larger scale trial. To compare the following secondary endpoints between the 2 arms: the rate of protocol violations, the intraoperative and postoperative morbidity of ePLND, and complications, and to evaluate short-term oncological outcomes comparing biochemical recurrence, clinical recurrence, and survival between arms. Patients and Methods A pilot study will be undertaken at Chris O’Brien Lifehouse and Royal Prince Alfred Hospitals for the NODE trial. Twenty patients will be randomised 1:1 to radical prostatectomy with or withoutePLND. Eligible participants will have high-risk prostate cancer and will be scheduled for robotic radical prostatectomy. High-risk disease will be defined as in the 2019 NCCN guidelines (stage ≥ T3a, ISUP Grade Group ≥ 4 or PSA ≥ 20ng/mL). PSMA PET/CT staging not showing any extraprostatic disease will be required. Quality control measures to ensure consistent delivery of high-quality extended lymph node dissections are in place,and surgeons have been selected for their consistent ability to perform such procedures. Results The trial is currently underway. Conclusion On current available evidence, it is unclear if ePLND provides additional benefit over radicalprostatectomy.","PeriodicalId":21961,"journal":{"name":"Société Internationale d’Urologie Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85427028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Private Practice in Jordan 约旦的私人诊所

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/ahop2343

Zeid Abughosh

引用次数: 0

Ambulatory Urodynamic Findings Change Patient Outcomes 动态尿动力学结果改变患者预后

Société Internationale d’Urologie Journal Pub Date : 2021-11-04 DOI: 10.48083/mhmi1178

R. Axell, V. Guzelburc, H. Yasmin*, B. Toia, M. Pakzad, R. Hamid, J. Ockrim, T. Greenwell

{"title":"Ambulatory Urodynamic Findings Change Patient Outcomes","authors":"R. Axell, V. Guzelburc, H. Yasmin*, B. Toia, M. Pakzad, R. Hamid, J. Ockrim, T. Greenwell","doi":"10.48083/mhmi1178","DOIUrl":"https://doi.org/10.48083/mhmi1178","url":null,"abstract":"Objectives Whilst ambulatory urodynamics (aUDS) may be used as a second-stage test for patients with refractory lower urinary tract symptoms (LUTS) having non-diagnostic conventional urodynamics (UDS), the evidence for their use is limited. We have assessed the diagnostic utility and consequent symptomatic outcome of aUDS in patients with refractory LUTS. Methods A retrospective review of a prospectively acquired urodynamics database was made of 84 consecutive patients (23 male) with a median age 50.5 years (range 18 to 79) having aUDS following non-diagnostic or contradictory baseline UDS over a 12-month period. Patient demographics and urodynamic and clinical diagnosis before and after aUDS were recorded. Forty-six patients (55%) had formal urinary symptom assessment recorded before and a minimum of 6 months following aUDS-related change in management. Results Eighty-two patients (98%) had a urodynamic diagnosis made following aUDS, 57(68%) of whom had detrusor overactivity (DO); the final 2 patients had no abnormalities detected on aUDS. Change in primary UDS diagnosis occurred in 66 patients (79%). Of these 66 patients, 59 (89%) also had their clinical diagnosis changed, and 55 (83%) had their management pathway changed. There was a significant improvement in urinary symptoms 6 months following aUDS. Conclusion Change in primary diagnosis following aUDS led to a significant change in treatment care pathway and resulted in significant improvement in urinary symptoms.","PeriodicalId":21961,"journal":{"name":"Société Internationale d’Urologie Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81434176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Adult Retroperitoneal Sarcoma: A Comprehensive Genomic Profiling Study 原发性成人腹膜后肉瘤:一项全面的基因组分析研究

Société Internationale d’Urologie Journal Pub Date : 2021-07-15 DOI: 10.48083/VOGF2319

A. Necchi, Giuseppe Basile, F. Pederzoli, M. Bandini, P. Grivas, G. Bratslavsky, P. Spiess, J. Killian, D. Lin, E. Williams, S. Ramkissoon, E. Severson, B. Alexander, J. Venstrom, P. Reddy, Kimberley McGregor, J. Elvin, A. Schrock, D. Pavlick, D. Jin, S. Trabucco, Natalie Danzinger, J. Ross

{"title":"Primary Adult Retroperitoneal Sarcoma: A Comprehensive Genomic Profiling Study","authors":"A. Necchi, Giuseppe Basile, F. Pederzoli, M. Bandini, P. Grivas, G. Bratslavsky, P. Spiess, J. Killian, D. Lin, E. Williams, S. Ramkissoon, E. Severson, B. Alexander, J. Venstrom, P. Reddy, Kimberley McGregor, J. Elvin, A. Schrock, D. Pavlick, D. Jin, S. Trabucco, Natalie Danzinger, J. Ross","doi":"10.48083/VOGF2319","DOIUrl":"https://doi.org/10.48083/VOGF2319","url":null,"abstract":"Background: Adult primary retroperitoneal sarcomas (RPSs) are a group of heterogeneous tumors with different histological subtypes. Comprehensive genomic profiling (CGP) analyses have recently provided significant insights into the biology of sarcomas by identifying genomic alterations (GAs) which could benefit from targeted therapies.\u0000Methods: RPS were evaluated by CGP using next-generation sequencing of up to 406 cancer-related genes. Tumor mutational burden (TMB) was determined on 0.83 to 1.14 mut/Mb of sequenced DNA. Finally, PD-L1 expression was determined.\u0000Results: Overall, 296 cases of primary RPS were analyzed. Liposarcoma (LPS) subtype had more GA/tumor than leiomyosarcoma (LMS) subtypes, with follicular dendritic cell sarcomas harboring the highest and synovial sarcomas the lowest. TP53 and Rb1 alterations were the highest in LMS, and CDK4/6 and MDM2 in LPS. However, both the\u0000TMB and targetable GA rates were low across subtypes. PD-L1 immunostaining was low positive in 21% and high positive in 5% of patients, respectively.\u0000Conclusions: CGP analysis revealed that potentially actionable genomic targets were rare in our cohort of RPS. Moreover, RPSs seem less likely to respond to immune checkpoint inhibitors based on putative biomarkers status. Nevertheless, genomic stratification according to histological subtypes led to description of GAs that can inform future clinical trials design.","PeriodicalId":21961,"journal":{"name":"Société Internationale d’Urologie Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84554411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Right Instrument for the Right Purpose: Spreading the Use of Small Caliber Ureteroscope for the Inspection of the Male and Female Urethra 正确的器械，正确的目的:推广小口径输尿管镜在男女尿道检查中的应用

Société Internationale d’Urologie Journal Pub Date : 2021-07-15 DOI: 10.48083/NVKO4969

S. Kulkarni, M. Bandini, Amey Y. Patil, S. Bhadranavar, Vipin Sharma, S. Bafna, S. L. Yatam, G. Barbagli, F. Montorsi, P. Joshi

引用次数: 4

Effect of Metallic Ureteric Stents on Magnetic Resonance Imaging: Implications for Malignant Ureteral Obstruction 金属输尿管支架对磁共振成像的影响:对恶性输尿管梗阻的影响

Société Internationale d’Urologie Journal Pub Date : 2021-07-15 DOI: 10.48083/WLVR1509

Mahima Tellambura, I. Thangasamy, Kwang Y. Chin, D. Murphy

引用次数: 1