动态尿动力学结果改变患者预后

R. Axell, V. Guzelburc, H. Yasmin*, B. Toia, M. Pakzad, R. Hamid, J. Ockrim, T. Greenwell
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摘要

虽然动态尿动力学(aUDS)可作为难治性下尿路症状(LUTS)患者的第二阶段检查,但常规尿动力学(UDS)无法诊断,但其使用的证据有限。我们评估了aUDS在难治性LUTS患者中的诊断效用和随之而来的症状结局。方法回顾性分析前瞻性获得的尿动力学数据库,包括84例连续患者(23例男性),中位年龄50.5岁(18 - 79岁),在12个月的时间里,在非诊断性或矛盾基线UDS下发生aUDS。记录aUDS前后患者人口统计学、尿动力学和临床诊断。46例患者(55%)在auds相关治疗改变前和改变后至少6个月进行了正式的泌尿系统症状评估。结果aUDS后尿动力学诊断为82例(98%),其中57例(68%)存在逼尿肌过度活动(DO);最后2例患者在aUDS上未发现异常。66例患者(79%)发生了原发性UDS诊断的改变。在这66例患者中,59例(89%)的临床诊断发生了改变,55例(83%)的治疗途径发生了改变。aUDS后6个月泌尿系统症状有显著改善。结论aUDS后原发性诊断的改变导致治疗护理途径的显著改变,导致泌尿系统症状的显著改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ambulatory Urodynamic Findings Change Patient Outcomes
Objectives Whilst ambulatory urodynamics (aUDS) may be used as a second-stage test for patients with refractory lower urinary tract symptoms (LUTS) having non-diagnostic conventional urodynamics (UDS), the evidence for their use is limited. We have assessed the diagnostic utility and consequent symptomatic outcome of aUDS in patients with refractory LUTS. Methods A retrospective review of a prospectively acquired urodynamics database was made of 84 consecutive patients (23 male) with a median age 50.5 years (range 18 to 79) having aUDS following non-diagnostic or contradictory baseline UDS over a 12-month period. Patient demographics and urodynamic and clinical diagnosis before and after aUDS were recorded. Forty-six patients (55%) had formal urinary symptom assessment recorded before and a minimum of 6 months following aUDS-related change in management. Results Eighty-two patients (98%) had a urodynamic diagnosis made following aUDS, 57(68%) of whom had detrusor overactivity (DO); the final 2 patients had no abnormalities detected on aUDS. Change in primary UDS diagnosis occurred in 66 patients (79%). Of these 66 patients, 59 (89%) also had their clinical diagnosis changed, and 55 (83%) had their management pathway changed. There was a significant improvement in urinary symptoms 6 months following aUDS. Conclusion Change in primary diagnosis following aUDS led to a significant change in treatment care pathway and resulted in significant improvement in urinary symptoms.
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