Siberian Journal of Life Sciences and Agriculture最新文献

{"title":"MORPHOLOGICAL AND QUANTITATIVE STUDIES OF THE HEMOCYTES IN NYMPH AND IMAGO OF BLAPTICA DUBIA (SERVILLE, 1839)","authors":"E. A. Grebtsova, A. Prisnyi","doi":"10.12731/2658-6649-2023-15-2-41-57","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-41-57","url":null,"abstract":"The purpose of the research is to analyze how the hemocyte counts and their morphological characteristics change during development of Blaptica dubia, especially during molting. And to suggest a possible scheme of the transformation of spherulocytes into crescent-cells. \u0000Materials and methods. Quantitative and morphological features of hemocytes of imago and nymphs of 1-4 stages of Blaptica dubia using light microscopy and AFM were researched. Cell, nucleus and granule sizes were determined using NIS-Elements and NOVA software. Cytochemical tests with neutral red and alcyan blue allowed us to identify different cell types. \u0000Results. This study presents a classification of hemocytes in Blaptica dubia, that based on morphological and cytochemical characteristics of cells. We analyzed the dynamics of the hemocytes counts in 6 nymphs (1-4 stages) and 6 imago. Special attention is given to the moment of molting. Seven hemocyte types were described and identified as: prohemocytes, plasmocytes, granulocytes, vermicytes, spherulocytes, coagulocytes and crescent-cells. The stem cells (prohemocytes) and spherulocytes were the predominant hemocytes. Prohemocytes counts decrease as a result of insect development, instead the relative number of plasmocytes and granulocytes increases. Spherulocytes counts could increase to 35% at the moment of leaving the ootheca and at the molting period. Due to the study of hemocytes diversity in different nymph stages, interim cells and possible ways of their transformations were identified. The unusual crescent-cells, that were unique for Gromphadorhina portentosa, had been found in Blaptica dubia. For the first time, the cytochemical test allowed to determine the origin of crescent-cells from spherulocytes.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42138745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CREATION OF A GEODATABASE ON GEOMORPHOMETRIC PARAMETERS OF THE RELIEF BY THE EXAMPLE OF THE NOVOSIBIRSK REGION USING SATELLITE IMAGES","authors":"A. I. Pavlova","doi":"10.12731/2658-6649-2023-15-2-125-138","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-125-138","url":null,"abstract":"Traditional methods of qualitative description of relief used in the process of landscape analysis, zoning, forecasting of exogenous processes, assessment of agricultural land do not allow to distinguish objectively forms of relief, to reveal statistically reliable relations between relief indicators and components of geosystems. For agro-ecological evaluation and land grouping with the help of modern methods of data classification, a geodatabase with quantitative indicators of relief is needed. Space images of high and medium spatial resolution are necessary for formation of geodata base of geomorphometric indicators during regional researches. Background. Quantitative (geomorphometric) indicators of relief are of great practical importance when identifying and describing landforms and relief elements. One or two indicators are often used for agricultural land assessment. In foreign literature various combined topographic indices are widely used for land classification. The scientific significance of the research is associated with modern methods of geomorphometric analysis of the relief based on remote sensing data and their application for automated mapping of relief types. Purpose. Creation of a geodatabase (GDB) of geomorphometric parameters of the Novosibirsk region on the basis of satellite data. Materials and methods. Digital modeling and geomorphometry methods were used in the work. Results. The database of geomorphometric parameters of the relief with the use of middle and high spatial resolution space images ALOP PALSAR (12.5 m/pixel) and ALOS DSM (30 m/pixel), topographic maps of M 1:25000 were developed. A geodatabase of geomorphometric parameters of the relief by the example of the Novosibirsk Region was developed including GIS information layers with geomorphometric parameters of the relief and attribute tables. The LGB has been used to map the types of relief in the Novosibirsk Region agrolandscapes. Automatic classification of relief types using multispectral images of K-Nearest Neighbor (KNN or k-NN, nearest neighbor) teacherless algorithms and the iterative self-organizing algorithm ISODATA (Self-Organizing Data Analysis) were performed. The input raster data for the terrain type classification were terrain parameters and vegetation indices NDVI, EVI, OSAVI, TSAVI, determined on the basis of multispectral satellite images Sentinel-2 A. By the example of Priobskiy central forest-steppe agrolandscape mapping of relief types was carried out: watershed drained undrained flat-leveled, watershed drained weakly drained, interfluvial undrained flatwaterlogged. The main relief-forming processes in the Priobskoye central forest-steppe agro-landscape are planar washout and waterlogging. Conclusion. Modern methods of geomorphometry and geoinformatics allow you to create a spatial database of geomorphometric parameters for a comprehensive assessment of the land on the basis of remote information. The use of a geomorphometric datab","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46919860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GENDER FEATURES OF THE TEENAGE ATHLETES’ LIFE QUALITY AND PERSONAL ANXIETY DYNAMICS (BY THE HEALTH SCHOOL LESSONS RESULTS)","authors":"Igor Yu. Khudonogov, Marina Pevneva, Kristina N. Lyashenko","doi":"10.12731/2658-6649-2023-15-2-195-220","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-195-220","url":null,"abstract":"Relevance. This work is devoted to social diagnostics and social prevention of possible negative side effects of medical, social and psychological plan that occur against the background of the main training and educational processes of pubertal athletes, taking into account their gender. \u0000Purpose: to assess the gender characteristics of the life quality and personal anxiety (PA) dynamics of the Brothers Samurgashevs’ Rostov Region Olympic Reserve Sports School No. 35 high school students against the background of classes at the health school (HS). \u0000Methods: historical, pedagogical, socio-psychological, social prevention, sociological, statistical and graphic methods, as well as the method of content analysis. \u0000Results: after the HS classes PA decreased more than 40% overall for the sample. The decrease in PA was accompanied by an increase in QoL by almost 15%. The main PA priorities for female athletes turned out to be the following signs: “You are in danger of failure, bad luck”; “To see bad or “prophetic” dreams”; “Something is not working out for you”. Among male athletes, the initial level of PA was lower than that of female by 40.1%. The priorities of male anxiety were such signs as: “You are in danger of failure, bad luck”; “They don’t pay attention to you”; “You can’t do your homework”. After HS classes, girls most quickly eliminated PA in such areas as “Waiting for parents after their personal conversation with the school principal” and “Seeing bad or “prophetic” dreams”, and boys - “You don’t understand the teacher’s explanations”, “(They) fell silent when you approached”, “Something is not working out for you”. The initial level of QoL of young female athletes was significantly lower by 8.7% than that of young male athletes, and after training at the HS, it exceeded the corresponding indicator in the group of young male athletes by 4.7%. After classes at the HS, young male athletes noted an improvement in relations during their studies (with peers, superiors, etc.), however, in quantitative terms, this improvement was 9 times lower than in the group of young female athletes. Also, young male athletes noted an improvement in their physical condition and strengthening of skills and abilities in organizing their time, but 5 and 4 times (respectively) less pronounced than in the group of young female athletes. \u0000Conclusion. The results obtained can be widely disseminated in similar sports schools to ensure monitoring and bringing the level of personal anxiety and quality of life of students to age norms.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49235162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FUNCTIONAL STATE OF THE AUTONOMIC NERVOUS SYSTEM IN ELDERLY PERSONS WITH POSTURAL INSTABILITY","authors":"T. P. Shiryaeva, D. Fedotov, I. N. Krainova, Navarro F. Ramirez","doi":"10.12731/2658-6649-2023-15-2-58-73","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-58-73","url":null,"abstract":"Background. Preservation of postural balance allows the elderly people to remain mobile and lead an active lifestyle. There is evidence of the contribution of the ANS to the coordination of postural responses and the maintenance of postural stability in young adults. However, similar data for the elderly is not enough and this issue requires further study. \u0000Purpose. To reveal the peculiarities of ANS functioning in elderly people with postural instability. \u0000Materials and methods. In 120 women aged 60-74 years, a survey, anthropometry, assessment of the dynamic component of postural balance by stabilometry and heart rate variability by cardiointervalography were performed. The study group included elderly people with postural instability (60 people), the control group included 60 women who did not report such facts. Data analysis was performed using “SPSS 27.0”. \u0000Results. The state of postural balance in the study group was characterized by a decrease in walking speed (p = 0.008) and a rise index when moving from the right leg (p = 0.016), an increase in the speed of oscillations of the center of body mass in the lifting phase (p = 0.047), oscillations of the center of gravity during rotation when moving on the left (p=<0.001) and right (p=0.003) legs, turn time when moving on the left (p=0.44) and right (p=0.36) legs. \u0000Conclusion. The results demonstrate a decrease in the quality and efficiency of postural balance regulation in elderly women with postural instability. We did not reveal any significant differences in the indicators characterizing the activity of different parts of the ANS depending on the facts of postural instability.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46836512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"METHODOLOGICAL ASPECTS OF LUNG ACOUSTIC IMPEDANSOMETRY","authors":"S. Dragan, A. Bogomolov, V. I. Kezik, S. V. Drozdov","doi":"10.12731/2658-6649-2023-15-2-221-242","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-221-242","url":null,"abstract":"Background. The pandemic caused by a new coronavirus infection has determined the relevance of the development of non-invasive methods for express examination of the function of external respiration in the interests of medical diagnostics and development of personal protective equipment against infectious diseases transmitted by airborne droplets. \u0000Purpose. The purpose was to study the possibility of increasing the information content of diagnosing the state of the respiratory system by measuring the acoustic impedance using the modernized two-microphone method. \u0000Materials and methods. An experimental study of the impedance and biophysical characteristics of the lungs was carried out on groups of healthy (12 heads) and patients with pneumonia (7 heads) male rabbits weighing 2.5-3 kg. To study the acoustic characteristics of the lungs, a direct method of impedancemetry based on a two-microphone measurement technique was used; the determination of the biophysical parameters of the lungs is based on measuring their weight and volume. \u0000Results. The fact of an increase in active energy losses of low-frequency acoustic oscillations during their propagation in the respiratory system has been experimentally established, which makes it possible to create an informative criterion for diagnosing its condition. When examining healthy lungs using acoustic impedancemetry, the active energy loss of acoustic vibrations at low frequencies should not differ significantly from the corresponding values of the energy loss of such vibrations at the resonant frequency. In case of violations of the conductivity of the airways or in the presence of exudate in the lungs, active losses at low frequencies will significantly exceed losses at the resonant frequency: the worse the condition of the lungs, the higher the losses. It has been established that the presence in the lungs of a cavity with its own resonant frequency leads to a decrease in the resistance of the respiratory system at these frequencies. \u0000Conclusion. The experimentally recorded fact of a decrease in resistance at frequencies below the resonant frequency of the respiratory system makes it possible to explain the insufficient diagnostic information content of pulsed oscillometry. To increase the sensitivity and specificity of pulsed oscillometry, it is necessary not to limit the determination of acoustic indicators only at frequencies of 5 and 20 Hz, but to determine them in an extended frequency range with a more detailed step.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44563170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GREEN TAXONOMY OF THE RUSSIAN AGRICULTURAL COMPLEX: CURRENT STATUS AND DIRECTIONS OF DEVELOPMENT","authors":"O. Tarasova, N. Prodanova, Yulia K. Kharakoz, N.D. Georgadze","doi":"10.12731/2658-6649-2023-15-2-337-362","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-337-362","url":null,"abstract":"А comprehensive analysis of the system of measures to stimulate and support the agro-industrial complex was carried out by the author; it was emphasized that such measures should be based (and are already rely to a large extent) on the principles of modern approaches to managing core industries. One of these fundamental principles is the use of the principles of the ESG agenda - green taxonomy strategies and methods. There are the principles and tools of green taxonomy in agriculture considered in detail in this paper, its current directions are presented, including on the basis of a systematic and comprehensive study of vectors of state support, resource conservation of such key components of the environment as air, water and soil. This study is important in understanding the growing global interest in reorienting public support for agriculture to transform agricultural and food systems into health-enhancing activities, Economy and planet, ensuring food safety, compliance with ESG principles. The article states that only an enabling environment with the necessary commitment to consistency of public administration in this area, a new legal framework, additional financial resources and local support structures will support the green transformation of the of the country’s agro-industrial system, which has already begun. \u0000Background. The agro-industrial complex of the Russian economy has traditionally been at the center of the political and economic agenda in our country for many years. Power and legislative institutions of various levels, including, first of all, the President and the Government of the Russian Federation, as well as the authorities of the subjects of the Federation, pay increased attention to the regulation and support of this sphere. And this is no coincidence because of the stable development issue of the agro-industrial complex is directly related to aspects of national food security – is a key factor in the functioning of the entire macroeconomic complex of the country, the well-being and stability of the population’s life. \u0000Purpose. The purpose of this work is to identify and analyze the effectiveness of a set of measures taken at the state level to stimulate and develop the “green agenda” of the Russian agro-industrial complex. \u0000Materials and methods. The legislative and regulatory acts of the Russian Federation, analytical reviews of leading Russian and international communities, Rosstat data, expert opinions of specialists in specific specialized areas, data from periodicals, works of Russian and foreign scientists in the field of agriculture were used during the preparation and writing the article. Analytical and empirical approaches to solving the tasks were used, abstract-logical methods of structuring information, systematic and complex analysis of existing information arrays of data, as well as general scientific logical approaches and methods of study were involved in the course of the research. \u0000Results. The present ","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44061811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHANGE CHARACTERISTICS IN SALIVA AND FECES MICROBIOTA OF A DESMINOPATHY T341P PATIENT","authors":"V. Pauls","doi":"10.12731/2658-6649-2023-15-2-265-283","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-265-283","url":null,"abstract":"Background. A rare muscular disease, desminopathy, is caused by mutations in the DES gene. At present, information about changes in the microbiota of biological media present in such patients is very scarce. \u0000Purpose. The aim of the study is to study changes in the saliva and feces microbiota of patients with desminopathy T341P in a heterozygous state. \u0000Materials and methods. The retrospective investigation comprised observation of the observation of a proband with the family form of desminopathy T341P. 56 clinically significant microorganisms were numerically analyzed immediately in the obtained biological material by gas chromatography-mass spectrometry method. \u0000Results. The emergence of Epstein-Barr viruses, Cytomegalovirus, Herpes spp and gram-negative rods was noted in the proband’s biological media under investigation during the desminopathy progression. Excessive bacterial growth of fecal microbiota was observed along with a decrease in saliva microorganisms. There is an excess of the norm in the total number of microorganisms and an increase in their species diversity. Propionibacterium jensenii, Eubacterium spp and Eggerthella lenta predominated in the feces and Clostridium ramosum – in the saliva. An increase in fecal microbiota transient with Peptostreptococcus anaerobius 18623 dominance was observed along with the emergence and rapid 441-time growth of potentially dangerous bacterium Clostridium difficile. The total level of endotoxin in the proband’s saliva and fecal microbiota increases to exceed the norm in 13.7 and 81.8 times, respectively. At the same time, a low level of plasmalogen was noted. \u0000Conclusion. The investigation results can be useful for developing complex intervention tactics.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43140021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ENSURING FOOD SECURITY THROUGH TRADE AND ECONOMIC COOPERATION BETWEEN SIBERIA AND THE EURASIAN ECONOMIC UNION","authors":"A. Bykov, D. V. Borisov, S. Ryumkin","doi":"10.12731/2658-6649-2023-15-2-470-484","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-470-484","url":null,"abstract":"The paper focuses on a critical issue of ensuring food security for countries that are members of the Eurasian Economic Union (EAEU), which is especially important given the transformation of the global food market in the context of the COVID-19 pandemic. The research aims (1) to assess the possibility of creating a single food market of the EAEU and (2) to identify the difficulties faced by the Siberian agricultural sector in addressing food security issues and export development. The paper presents the results of the study concerning the development of trade and economic cooperation between the Siberian Federal District (SFD) of the Russian Federation and the EAEU countries with regard to the agricultural market. Based on the statistical analysis of national data, we examined the particular aspects of Siberian agricultural export development. We were able to identify the largest trading partners among the EAEU member states and study the particular aspects of their food imports based on the Russian database indicators. According to the analysis results, we concluded that exports are dominated by food products, namely intermediate and final products, which correspond to the objectives of the Russian Federation National Project International Cooperation and Exports. Market research on the breakdown of imports to the EAEU showed that it imported dairy products, fruits, vegetables, and processed foods. We identified the most promising areas of export development for the SFD based on a review of the scientific studies on economic integration and food security issues. The scientific novelty of this research lies in proving the need to develop exports of finished food products with a high level of processing, which requires the integrated development of the food processing industry in the SFD by means of regional strategic programs for introducing innovative biotechnologies in deep processing of agricultural raw materials. The research findings might be of great interest to members of the academic community and undergraduate and graduate students pursuing similar research agendas.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46237380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHOLINE PREPARATIONS IN THE TREATMENT OF ASTHENIC STATES: MODERNITY AND PERSPECTIVES (A LITERATURE REVIEW WITH A CLINICAL CASE PRESENTATION)","authors":"Kamila Sh. Magomedova, Y. Bykov, R. Bekker","doi":"10.12731/2658-6649-2023-15-2-392-434","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-392-434","url":null,"abstract":"Purpose. To provide the reader with a detailed description of the biochemical and physiological effects of choline, which make it an indispensable component of our daily food. Then to thoroughly review all the relevant clinical data on the use of choline preparations for the treatment of asthenic and astheno-depressive conditions and cognitive impairments. Then, to present the reader with a clinical case from our own practice, illustrating the effectiveness of the use of choline alfoscerate as part of the combination therapy of a mild form of post-COVID astheno-depressive syndrome in a 19-year-old man who have refused to take antidepressants, as well as any other psychotropic drugs, but instead wanted some form of pharmacotherapy based exclusively on «natural components». \u0000Methodology. We have searched PubMed, Google Scholar, Web of Science databases for keywords such as «choline biochemistry», «choline and phospholipids», «choline and betaine», «arsenolipids», «nitrolipids», «choline and cognition», «choline and asthenia». Then we filtered the data we had found by their relevance. Then we summarized and presented the relevant data in the theoretical part of this article. Then we described in detail the clinical case of the effective use of choline alfoscerate in the complex therapy of post-COVID asthenic-depressive state which we have encountered in our own practice. \u0000Results. The results we have obtained during compilation of this review, in our opinion, may allow us to draw preliminary conclusions about the possible prospects for the use of choline preparations (and, in particular, choline alfoscerate preparations) in monotherapy or as part of combination therapy of asthenic and / or astheno-depressive states (especially if those states are accompanied by impaired memory, concentration, increased mental fatigue), including those states that were caused by a recent history of COVID-19 (that is, asthenic or astheno-depressive states developed as part of the post-covid syndrome). \u0000To be able to make any further, more firm conclusions regarding the efficacy and safety of the use of choline-containing preparations in this context, it will be necessary to organize and conduct large, multicenter, methodologically sound, double-blind, placebo-controlled, randomized clinical trials (RCTs), with clinically meaningful and relevant outcomes in the treatment of asthenia clearly defined as trial endpoints in advance (before starting the trial itself). \u0000Practical implications. We believe that the results we have presented in this review justify the need to further study the efficacy and safety of the use of choline preparations, both as monotherapy and as a part of combination therapy of asthenic and astheno-depressive conditions, preferably in the format of large, multicenter, well organized, methodologically sound, double-blind, placebo-controlled RCTs with clearly pre-defined clinically meaningful and relevant endpoints.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46837295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTERRELATION SYSTEM OF TRANSFORMATIONAL PROCESSES OF AGRICULTURAL ECONOMIC STRUCTURES AND PROBLEMS OF SUSTAINABLE FOOD SECURITY","authors":"T. Maksimova, T. Bondarenko, O. Zhdanova, N. Prodanova","doi":"10.12731/2658-6649-2023-15-2-485-506","DOIUrl":"https://doi.org/10.12731/2658-6649-2023-15-2-485-506","url":null,"abstract":"The relevance of the problem under study is connected with the identification of the relationship between the transformation processes of agrarian structures and issues of sustainable food security; with the definition of contradictions and uncertainties of the harmonious interaction of different forms of management formed in the process of transformation; revealing their functional differences; typology and scenario forecasts of development. The dualistic nature of the results of the transformation of the main forms of management in the system of the national economy is substantiated. \u0000Purpose. Identification of key aspects of the specifics of the results of transformational processes of economic structures in the agrarian economy of the Russian Federation and substantiation of the importance of a harmonious relationship with each other in accordance with the tasks of food security in the face of modern challenges. \u0000Materials and methods. The methodology of an integrated approach was used based on the systematic approach of Western and Russian researchers, as well as on the methodology of small economic structures Chayanova A.V., Kondratieva N.D. Methods of comparative economic analysis using the data of official statistics of the Russian Federation and FAO, as well as methods of visualizing the results of the study are involved. The case method was used to study the specifics of various economic structures, and the scenario modeling method was used to determine the trends for further development. \u0000Results. Based on a comparative analysis of the results of the market transformation of economic structures and the economic effects of their activities, it was revealed that: firstly, the dynamics and rates of food inflation in the system of the Russian economy are lower than the global ones; secondly, large economic structures prevail in the structure of production and rates of output of food products; thirdly, the predominance of market power on the part of large economic structures leads to the deformation of market relations and the need to find a solution to the problem of creating equal opportunities for large and small economic structures. \u0000Conclusion. The importance of creating a model of harmonious relations between different forms of management is substantiated. Scenario forecasts of possible trends in the further development of small and large economic structures have been made.","PeriodicalId":21854,"journal":{"name":"Siberian Journal of Life Sciences and Agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44879151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}