Seminars in respiratory and critical care medicine最新文献

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Management of Chronic Neuromuscular Respiratory Failure in the Intensive Care Unit. 重症监护病房慢性神经肌肉呼吸衰竭的管理。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-07 DOI: 10.1055/s-0044-1788551
Mustafa H Ghanem, Won Lee, Bethany L Lussier
{"title":"Management of Chronic Neuromuscular Respiratory Failure in the Intensive Care Unit.","authors":"Mustafa H Ghanem, Won Lee, Bethany L Lussier","doi":"10.1055/s-0044-1788551","DOIUrl":"https://doi.org/10.1055/s-0044-1788551","url":null,"abstract":"<p><p>In this seminar we describe the critical care management of patients with chronic neuromuscular diseases (cNMD). Determination of the acuity of the critical illness and trajectory of illness in the setting of cNMD is necessary to guide decision making. Systemic complications of critical illness, cardiac support needs, and peri-intubation considerations may be affected by underlying diagnosis. Mechanical ventilatory support, whether noninvasive or invasive, requires redefinition of the goals of ventilation on a patient-by-patient basis. Mode and approach to invasive ventilation and liberation to noninvasive ventilation versus tracheostomy have limited evidence, but potential clinical approaches are reviewed.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Vascular Disease in Chronic Obstructive Pulmonary Disease. 慢性阻塞性肺病中的肺血管疾病。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-11-12 DOI: 10.1055/s-0044-1791824
Dana Kay, Roberto Bernardo, Jean Elwing
{"title":"Pulmonary Vascular Disease in Chronic Obstructive Pulmonary Disease.","authors":"Dana Kay, Roberto Bernardo, Jean Elwing","doi":"10.1055/s-0044-1791824","DOIUrl":"https://doi.org/10.1055/s-0044-1791824","url":null,"abstract":"<p><p>Pulmonary hypertension (PH) is a vascular disease characterized by pulmonary artery remodeling and right heart failure. PH related to COPD is a precapillary form of the disease, with hemodynamic measurements including a mean pulmonary artery pressure of greater than 20 mm Hg, a wedge pressure of less than 15 mm Hg, and a pulmonary vascular resistance of greater than 3 WU (Woods units), categorized under the World Health Organization classification as group 3. The presence of PH in COPD has been known to increase morbidity and mortality. Limited studies have evaluated treatment options for PH related to COPD.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":"45 5","pages":"574-581"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future Considerations and Areas for Innovation for Pulmonary Rehabilitation in Chronic Obstructive Lung Disease Patients. 慢性阻塞性肺病患者肺康复的未来考虑因素和创新领域。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-10-25 DOI: 10.1055/s-0044-1791825
John W Connell, Scott A Humason, Ralph J Panos, Robert Burkes
{"title":"Future Considerations and Areas for Innovation for Pulmonary Rehabilitation in Chronic Obstructive Lung Disease Patients.","authors":"John W Connell, Scott A Humason, Ralph J Panos, Robert Burkes","doi":"10.1055/s-0044-1791825","DOIUrl":"10.1055/s-0044-1791825","url":null,"abstract":"<p><p>Pulmonary rehabilitation is an effective therapy that improves day-to-day symptoms and quality of life in patients with chronic obstructive pulmonary disease. In this review, we look at the role of virtual programs, implementation of artificial intelligence, emerging areas of improvement within the educational components of programs, and the benefit of advanced practice providers in directorship roles.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":"605-610"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142507455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Marijuana Use on Lung Health. 吸食大麻对肺部健康的影响。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-07-05 DOI: 10.1055/s-0044-1785679
Joanne M Bando, Donald P Tashkin, Igor Z Barjaktarevic
{"title":"Impact of Marijuana Use on Lung Health.","authors":"Joanne M Bando, Donald P Tashkin, Igor Z Barjaktarevic","doi":"10.1055/s-0044-1785679","DOIUrl":"10.1055/s-0044-1785679","url":null,"abstract":"<p><p>The widespread use of marijuana in the context of increasing legalization has both short- and long-term health implications. Although various modes of marijuana use-smoked, vaped, or ingested-may lead to a wide scope of potential systemic effects, we focus here on inhalational use of marijuana as the most common mode with the lung as the organ that is most directly exposed to its effects. Smoked marijuana has been associated with symptoms of chronic bronchitis and histopathologic changes in airway epithelium, but without consistent evidence of long-term decline in pulmonary function. Its role in immunomodulation, both for risk of infection and protection against a hyperinflammatory host response to infection, has been suggested in animal models and in vitro without conclusive extrapolation to humans. Marijuana smoke contains carcinogens like those found in tobacco, raising concern about its role in lung cancer, but evidence is mixed and made challenging by concurrent tobacco use. Vaping may offer a potential degree of harm reduction when compared with smoking marijuana with reduction of exposure to several toxins, including carbon monoxide, and reduction in chronic respiratory symptoms. However, these potential benefits are counterbalanced by risks including vaping-associated lung injury, potentially more intense drug exposure, and other yet not well-understood toxicities. As more states legalize marijuana and the federal government considers changing this from a Schedule I to a Schedule III controlled substance, we anticipate an increase in prospective medical studies concerning the risks related to marijuana use. This review is based on currently available data concerning the impact of inhaled marijuana on lung health.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":"548-559"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in the Understanding and Management of Chronic Obstructive Pulmonary Disease. 慢性阻塞性肺病的认识和管理进展》(Advances in the Understanding and Management of Chronic Obstructive Pulmonary Disease)。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-11-12 DOI: 10.1055/s-0044-1791738
Robert Burkes, Christina MacRosty
{"title":"Advances in the Understanding and Management of Chronic Obstructive Pulmonary Disease.","authors":"Robert Burkes, Christina MacRosty","doi":"10.1055/s-0044-1791738","DOIUrl":"https://doi.org/10.1055/s-0044-1791738","url":null,"abstract":"","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":"45 5","pages":"541-542"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating COPD in Aging Populations: Insights Into Pathophysiology and Comprehensive Care. 老龄人群慢性阻塞性肺病的护理:洞察病理生理学和综合护理。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-11-12 DOI: 10.1055/s-0044-1792112
William T Atchley, Amy Montgomery, Rohan Seth, Tanmay Gandhi, Shannon Brewer
{"title":"Navigating COPD in Aging Populations: Insights Into Pathophysiology and Comprehensive Care.","authors":"William T Atchley, Amy Montgomery, Rohan Seth, Tanmay Gandhi, Shannon Brewer","doi":"10.1055/s-0044-1792112","DOIUrl":"https://doi.org/10.1055/s-0044-1792112","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) poses a significant and growing health burden among aging populations, marked by increasing prevalence and complex management challenges specific to elderly patients. This review explores the multifaceted interplay between COPD and aging, highlighting overlapping pathophysiological processes and comorbidities that complicate diagnosis and treatment. We examine age-specific management strategies, emphasizing the need for tailored approaches that account for the unique physical, cognitive, and health-related quality of life impacts on older adults. Additionally, we discuss preventive treatments and the critical roles of mental health, end-of-life care, and caregiver support in comprehensive disease management. The importance of integrative approaches to enhancing health care delivery is also underscored. Finally, we outline future directions, focusing on novel treatment pathways and the identification of biomarkers for early detection. Addressing these elements is essential for optimizing care in this vulnerable population and alleviating the significant societal and economic impacts of COPD among aging patients.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":"45 5","pages":"560-573"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bronchoscopic Lung Volume Reduction: A Review. 支气管镜肺容积缩小术:综述。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-07-18 DOI: 10.1055/s-0044-1787876
Shreya Podder, Marium Khan, Zane Sink, Steven Verga, Jonathan S Kurman, Elizabeth Malsin
{"title":"Bronchoscopic Lung Volume Reduction: A Review.","authors":"Shreya Podder, Marium Khan, Zane Sink, Steven Verga, Jonathan S Kurman, Elizabeth Malsin","doi":"10.1055/s-0044-1787876","DOIUrl":"10.1055/s-0044-1787876","url":null,"abstract":"<p><p>Bronchoscopic lung volume reduction (BLVR) is an established treatment modality for the management of advanced chronic obstructive pulmonary disease complicated by severe emphysema and hyperinflation refractory to other therapies. BLVR aims to reduce hyperinflation and residual volume, thereby improving pulmonary function, symptom control, and quality of life. Multiple distinct devices and technologies, including endobronchial coils, thermal vapor ablation, bio-lung volume reduction, and airway bypass stenting, have been developed to achieve lung volume reduction with varying degrees of accessibility and evidence. The most promising BLVR treatment modality to date has been the placement of one-way endobronchial valves (EBVs), with more than 25,000 cases performed worldwide. Identifying symptomatic patients who would benefit from BLVR is challenging and can be time and resource intensive, and candidacy may be limited by physiologic parameters. Additional new technologies may be able to improve the identification and evaluation of candidates as well as increase the portion of evaluated patients who ultimately qualify for BLVR. In this review, we aim to provide historical context to BLVR, summarize the available evidence regarding its use, discuss potential complications, and provide readers with a clear guide to patient selection and referral for BLVR, with a focus on EBV placement. In addition, we will highlight potential future directions for the field.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":"593-604"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung Transplant for Chronic Obstructive Pulmonary Disease. 肺移植治疗慢性阻塞性肺病。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-07-19 DOI: 10.1055/s-0044-1787560
Kyle Swartz, Ali Mansour, Sammar Alsunaid
{"title":"Lung Transplant for Chronic Obstructive Pulmonary Disease.","authors":"Kyle Swartz, Ali Mansour, Sammar Alsunaid","doi":"10.1055/s-0044-1787560","DOIUrl":"10.1055/s-0044-1787560","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) carries a high burden of morbidity and mortality to patient and a high cost to health care systems. Lung transplantation is a last resort available for end-stage COPD patients interested in pursuing it and meeting the strict transplant requirements. It requires commitment from patients and their loved ones to support them through this tough process. This review will cover history of transplant, indications, candidate selection, evaluation testing, transplant listing, type of transplant (single versus bilateral), posttransplant complications, immunosuppression, and rejection. It is tailored to the COPD patient when applicable; however, many aspects of lung transplantation are shared amongst all lung diseases eligible for transplant.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":"611-618"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing Interventions for Chronic Obstructive Pulmonary Disease. 制定慢性阻塞性肺病干预措施。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-07-05 DOI: 10.1055/s-0044-1787875
Audra J Schwalk, Niral M Patel, Nagendra Y Madisi
{"title":"Developing Interventions for Chronic Obstructive Pulmonary Disease.","authors":"Audra J Schwalk, Niral M Patel, Nagendra Y Madisi","doi":"10.1055/s-0044-1787875","DOIUrl":"10.1055/s-0044-1787875","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is an incurable, progressive respiratory disease that may have a significant negative impact on the morbidity and mortality of affected patients. A substantial portion of the world's population is affected by COPD, and despite optimal medical management with medications, supplemental oxygen, and pulmonary rehabilitation, many patients are left debilitated because of this disease. Bronchoscopic treatment modalities offer a less-invasive method for the treatment of refractory COPD compared to surgical interventions and have expanded the potential therapeutic options for these patients. Bronchoscopic lung volume reduction is aimed at decreasing the hyperinflation and air trapping that occur in emphysema, and the most studied and successful intervention is endobronchial valve placement. Endobronchial coils, polymeric sealants, and thermal ablation are other researched alternatives. Additional interventional procedures are being investigated for the treatment of the mucus hypersecretion and cough that are associated with the chronic bronchitis phenotype of COPD and include targeted lung denervation, metered dose spray cryotherapy, deobstruction balloon, and bronchial rheoplasty. This review summarizes the most recent evidence pertaining to available therapies for the management of COPD, including chronic bronchitis, with a particular focus on bronchoscopic interventions.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":"582-592"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Viral Infections in the Development and Progression of COPD. 病毒感染在慢性阻塞性肺病的发生和发展中的作用。
IF 2.3 3区 医学
Seminars in respiratory and critical care medicine Pub Date : 2024-10-01 Epub Date: 2024-10-25 DOI: 10.1055/s-0044-1791737
Robert Burkes
{"title":"The Role of Viral Infections in the Development and Progression of COPD.","authors":"Robert Burkes","doi":"10.1055/s-0044-1791737","DOIUrl":"10.1055/s-0044-1791737","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is a common chronic disease seen in smokers associated with poor functional status, quality of life, and morbidity and mortality from acute worsening of chronic symptoms, also called exacerbations. As a disease, the risk factors for COPD are well defined; however, there is room for innovation in identifying underlying biological processes, or \"endotypes,\" that lead to the emergence and/or progression of COPD. Identifying endotypes allows for more thorough understanding of the disease, may reveal the means of disease prevention, and may be leveraged in novel therapeutic approaches. In this review, we discuss the interface of viral infections with both cellular and epithelial immunity as a potential endotype of interest in COPD.</p>","PeriodicalId":21727,"journal":{"name":"Seminars in respiratory and critical care medicine","volume":" ","pages":"543-547"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142507458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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