上海口腔医学最新文献

{"title":"[Application of T1-T2 dual-mode cobalt manganese oxide nanoparticle MRI contrast agent in the diagnosis of oral squamous cell carcinoma].","authors":"Hongtao Xu, Han Cheng, Fangjie Li, Chongyang Zheng, Xiaojuan Huang, Zhiyuan Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To develop an efficient and low-toxicity T1-T2 dual-mode magnetic resonance (MR) nano-contrast agent (cobalt manganese oxide @ hyaluronic acid, CMO@HA) as a safe and effective strategy for the diagnosis of oral squamous cell carcinoma (OSCC).</p><p><strong>Methods: </strong>CMO@HA was synthesized via a multi-step process and characterized for its morphology and composition using transmission electron microscopy(TEM) and X-ray diffraction (XRD). MR imaging of CMO@HA suspensions at various concentrations was performed to acquire T1- and T2-weighted images and relaxation times. The longitudinal and transverse relaxivities were calculated using linear regression analysis. A xenograft mouse model was established to evaluate the in vivo tumor imaging performance of CMO@HA. Biocompatibility was assessed through CCK-8 cell viability assays, live-dead cell staining and HE staining of major organs.</p><p><strong>Results: </strong>CMO@HA was successfully synthesized with an average particle size of approximately 12 nm and a zeta potential of -16.6 mV. In MRI, CMO@HA solutions exhibited concentration-dependent T1-T2 dual-enhanced imaging characteristics, with longitudinal and transverse relaxivities of 1.005 (mmol/L)^-1s^-1 and 11.84 (mmol/L)^-1s^-1, respectively. In the xenograft mouse model, intratumoral injection of CMO@HA resulted in an enhancement of T1-weighted and T2-weighted signals at the tumor site by (46.98±14.51)% and (26.04±6.9)%, respectively. Biocompatibility assessments revealed that after co-incubation with 100 μg/mL CMO@HA, the cell viability remained at 98%, live-dead staining results showed no significant differences compared to the control group. During a 7-day observation period, CMO@HA-treated mice exhibited stable body weights comparable to the control group, and no pathological damage or liver and kidney dysfunction was observed in major organs.</p><p><strong>Conclusions: </strong>CMO@HA is a nano-contrast agent with excellent T1-T2 dual-mode MR imaging enhancement capabilities and favorable biocompatibility. It significantly improves the imaging contrast between tumor and normal tissues, providing a viable imaging solution for early diagnosis of OSCC.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cyclic tensile strain promotes osteogenic differentiation and angiogenic activity of mouse pericytes].","authors":"Daphne Yuchen Chin, Xinyue Tang, Ning Zhao, Guohua Tang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of cyclic tensile strain on osteogenic differentiation and angiogenic activity of mouse pericytes (PCs).</p><p><strong>Methods: </strong>Primary mouse brain microvascular PCs were isolated and cultured, and the membranous markers were detected by flow cytometry. Flexcell loading system was used to apply 6% cyclic tensile strain to the cells. Mouse bone marrow mesenchymal stem cells (BMSCs) were used as a positive control. Alkaline phosphatase (ALP) assay, alizarin red (AR) staining and Matrigel angiogenesis test were used to evaluate the effects of mechanical strain on the osteogenic differentiation and angiogenic activity of PCs. The expression levels of osteogenic and angiogenic genes were determined by qRT-PCR.</p><p><strong>Results: </strong>The PCs expressed the characteristic mouse stem cell surface proteins CD29+CD44+CD45-CD31- and highly expressed PDGFRβ. Under 6% cyclic strain, the ALP activity of PCs increased by 1.6-fold and the AR activity by 2.9-fold. Similarly, the ALP and AR activities of BMSCs were increased by 1.5 and 3.9 times, respectively. Matrigel angiogenesis assay showed that the angiogenic activity of human umbilical vein endothelial cells (HUVECs) was induced by conditioned medium from PCs and BMSCs under mechanical strain. qRT-PCR showed that the expressions of RUNX2, OCN and IBSP were higher in PCs under mechanical strain, and the expressions of VEGF and VEGFR1 were higher in BMSCs.</p><p><strong>Conclusions: </strong>Cyclic tensile strain promotes osteogenic differentiation and angiogenic activity of PCs.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"13-18"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of the effect of biological functional complete denture in repairing middle-aged and elderly patients with missing dentition].","authors":"Tingting Duanmu, Fan Lei, Qinqin Wang, Hong Sun","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effect of biological functional complete denture in the repair of middle-aged and elderly patients with missing dentition.</p><p><strong>Methods: </strong>One hundred and one middle-aged and elderly patients with complete denture loss from February 2021 to March 2024 were retrospectively analyzed.They were divided into the control group (traditional complete denture, n=52) and the experimental group (biological functional complete denture, n=49) according to different restoration methods. Masticatory function, EMG activity of masticatory muscle, clinical efficacy, comfort level, oral health and patient satisfaction were compared between the two groups.</p><p><strong>Results: </strong>Three months after treatment, the masticatory efficiency and absorbance of masticatory substances were significantly increased in 2 groups (P＜0.05), and those in the experimental group were higher (P＜0.05). Surface electromyography and asymmetry index (AI) of anterior temporal tract and masseter muscle in the experimental group were significantly lower than those in the control group(P＜0.05), and the total effective rate was significantly higher than that in the control group(P＜0.05). Three months after treatment, the scores of general comfort questionnaire(GCQ) in 2 groups were significantly increased (P＜0.05), and those in the experimental group were higher (P＜0.05); the score of oral health impact profile-14(OHIP-14) was decreased in both groups(P＜0.05), and was lower in the experimental group (P＜0.05). Satisfaction rate of patients in the experimental group was significantly higher than the control group (P＜0.05).</p><p><strong>Conclusions: </strong>Biofunctional complete denture restoration can improve the comfort and oral health status of middle-aged and elderly patients with denture loss, enhance the masticatory function and the myoelectric activity of masticatory muscle, and improve patient satisfaction.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"72-76"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A CBCT study on the inclination of the maxillary occlusal plane and related measurements in adolescent skeletal ClassⅠand ClassⅡpatients with normal vertical angles].","authors":"Yuanfeng Ding, Xiangbing Wu, Yunxia Gao, Yingyuan Sun, Qingqing Li, Lijuan Song","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the differences and correlations in the inclination of the maxillary anterior and posterior occlusal planes, mandibular plane angle, mandibular angles(total angle, upper angle, lower angle), and lower facial height between adolescent patients with skeletal Class Ⅰ and skeletal Class Ⅱ normodivergent facial patterns based on CBCT, so as to provide a reference for orthodontic diagnosis and treatment of these two groups of patients.</p><p><strong>Methods: </strong>A total of 37 adolescent patients with skeletal Class Ⅰ normodivergent facial pattern and 37 with skeletal Class Ⅱ normodivergent facial pattern who received orthodontic treatment at Suzhou Stomatological Hospital from January 2023 to December 2023 were selected. CBCT scanning and Dolphin Imaging 11.95 software were used to reconstruct lateral cephalograms. The inclinations of the maxillary anterior occlusal plane and posterior occlusal plane, as well as the total mandibular angle, upper mandibular angle, lower mandibular angle, lower facial height, mandibular plane angle(MP-FH), SNA angle, SNB angle, and ANB angle were measured.</p><p><strong>Results: </strong>The inclinations of the maxillary anterior and posterior occlusal planes in the skeletal Class Ⅱ group were significantly greater than those in the skeletal Class Ⅰ group(P＜0.01); the total mandibular angle, lower mandibular angle, lower facial height, and mandibular plane angle in the skeletal Class Ⅱ group were significantly larger than those in the skeletal Class Ⅰ group(P＜0.05); the SNA angle in the skeletal Class Ⅱ group was larger (P＜0.05), while the SNB angle was smaller (P＜0.01). In both groups, the inclinations of the maxillary anterior and posterior occlusal planes were positively correlated with the lower facial height and mandibular plane angle, with statistically significant correlations(P＜0.05); they were negatively correlated with the SNA angle and SNB angle, and positively correlated with the ANB angle, among which the correlations in the skeletal Class Ⅱ group were statistically significant (P＜0.05).</p><p><strong>Conclusions: </strong>The inclinations of the maxillary anterior and posterior occlusal planes are related to the sagittal and vertical skeletal facial patterns; they are positively correlated with the mandibular plane angle, lower facial height, and ANB angle, which negatively correlates with the SNA angle and SNB angle.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of the efficacy of three different bone removal methods in the extraction of mesial and low impacted mandibular wisdom teeth].","authors":"Qian Zhou, Tingfei Qin, Xucai Qin","doi":"","DOIUrl":"","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To evaluate the effect of Er:YAG laser, piezosurgery and high-speed turbine drill in the extraction of mesial and low impacted mandibular wisdom teeth.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 119 patients with mesial and low mandibular impacted wisdom teeth who were admitted from April 2021 to July 2023 were selected and divided into group A(n=38), group B(n=40) and group C(n=41) according to different bone removal methods. Group A was treated with high-speed turbine drilling, group B was treated with Er:YAG laser and group C was treated with piezosurgery. Postoperative indexes, visual analogue score (VAS) of postoperative pain, facial swelling, mouth opening limitation, complications and postoperative satisfaction were compared among the three groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The intraoperative blood loss in group C was significantly lower than that in groups A and B (P＜0.05), and that in group B was significantly lower than that in group A (P＜0.05). The tooth extraction time in group B was significantly longer than that in groups A and C(P＜0.05), and that in group C was significantly longer than that in group A (P＜0.05). Pain VAS of the three groups on the 7th day after surgery was significantly lower than that on the 1st day after surgery (P＜0.05), and pain VAS of groups B and C were significantly lower than that of group A (P＜0.05), but there was no significant difference between group B and C (P＞0.05). The degree of facial swelling on the 7th day after surgery in the three groups was significantly lower than that on the 3rd day after surgery(P＜0.05), and groups B and C were significantly lower than group A(P＜0.05), but there was no significant difference between groups B and C(P＞0.05). The degree of mouth opening limitation on the 7th day after surgery in the three groups was significantly lower than that on the 3rd day after surgery (P＜0.05), and groups B and C were significantly lower than group A (P＜0.05), but there was no significant difference between groups B and C(P＞0.05). There was no significant difference in the total incidence of complications among the three groups(P＞0.05). The postoperative satisfaction of group C was significantly higher than group A and group B(P＜0.05), and the postoperative satisfaction of group B was significantly higher than group A(P＜0.05). Multivariate logistic regression analysis revealed that operation time ＜20 min, intraoperative blood loss＜5 mL and intraoperative pain VAS ＜2 were independent protective factors for the improvement of patients' satisfaction (P＜0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Compared with Er:YAG laser, high-speed turbine drill and piezosurgery have better effects in the extraction of mesial and low mandibular impacted wisdom teeth. Both of them can reduce postoperative pain and intraoperative trauma, improve the degree of facial swelling and mouth opening limitation of patients. Moreover, compared with high-speed turbo drill and Er:YAG l","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"66-71"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical evaluation of the influence of different types of appliances on Chinese phonetic function of orthodontic patients].","authors":"Aili Shen, Bixia Wang, Ziyang Liu, Liping Jiang, Jiaqiang Liu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the effects of different orthodontic appliances on the clarity of Mandarin speech and the error rate of consonants in orthodontic patients.</p><p><strong>Methods: </strong>A total of 89 orthodontic patients treated in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from January 2024 to September 2024 were included. According to the type of appliance, the patients were divided into three groups: metallic appliance group, ceramic appliance group and invisible aligner group. Speech assessment was performed before, immediately after appliance placement and 1 month after appliance placement, respectively, and the speech clarity and consonant error rate of the three groups were compared.</p><p><strong>Results: </strong>An immediate decrease in speech clarity was observed with all three types of appliances(P＜0.001). However, there was no significant difference between the three groups of patients in the changes of speech clarity, both immediately after wearing and one month after wearing the appliances. The error rates for /j/, /x/, /s/, /zh/, /ch/ and /sh/ in the metallic appliance group were higher immediately after wearing the appliance than before wearing them, but returned to baseline after 1 month; the error rates of /q/, /z/ and /c/ had not returned to baseline levels even after one month. In ceramic appliance group, the error rates for /j/, /q/, /x/, /c/, /zh/, /ch/ and /sh/ were higher immediately after wearing the appliance than before wearing them, but returned to baseline after one month. The error rate for /z/ had not returned to baseline levels even after one month. The error rates for /j/, /q/, /zh/, /ch/ and /sh/ in the invisible aligner group were higher immediately after wearing the appliance than before wearing them, but returned to baseline at one month. The error rates for /x/, /z/, /c/, and /s/ had not returned to baseline levels even after one month. The incidence of new speech errors for /z/ immediately after wearing the invisible appliance was higher than that of the metal and ceramic appliance groups(P＜0.05), but there was no significant difference in other consonant error rates among the three groups(P＞0.05).</p><p><strong>Conclusions: </strong>The placement of metal, ceramic and invisible aligner can all lead to an immediate decrease in speech clarity for patients, with no significant differences among the three types of appliances. After wearing for one month, speech clarity of the three groups showed improvement. In terms of the incidence of newly occurring consonant errors, only the /z/ sound demonstrated a significant difference immediately after wearing, with the invisible aligner group exhibiting a higher error rate compared to the metallic and ceramic group.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"42-47"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Osteogenic effects and molecular biological evaluation of L-PRF combined with deproteinized bovine bone mineral in external maxillary sinus lift implantation].","authors":"Xiu Yao, Yilin Tu, Chenyang Zhang, Xiaoming Xu, Zhengjie Dong","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the clinical osteogenic effect and molecular mechanism of the combined application of leucocyte platelet-rich fibrin(L-PRF) and deproteinized bovine bone mineral(DBBM) in lateral window maxillary sinus floor elevation and bone grafting surgery.</p><p><strong>Methods: </strong>A total of 40 patients who underwent lateral window maxillary sinus floor elevation and bone grafting at Shanghai Stomatological Hospital from January 2023 to March 2025 were selected and divided into two groups: the control group (treated with DBBM alone, n=20) and the experimental group (treated with DBBM combined with autologous L-PRF, n=20). At 3 and 6 months after surgery, histological and molecular biological analyses were performed to evaluate the osteogenic volume, osteogenic activity, collagen formation, and bone mineralization in the bone graft area. RNA sequencing (RNA-seq) and immunohistochemical staining (IHC) were used to further analyze the relevant molecular mechanisms.</p><p><strong>Results: </strong>The osteogenic volume and activity of the experimental group at 3 and 6 months after surgery were significantly higher than those of the control group (P＜0.05). In the experimental group, collagen formation was significant at 3 months, and bone remodeling was more obvious at 6 months with the formation of Haversian canals(P＜0.05). RNA-seq analysis showed that the expression level of COL10A1 in the experimental group was significantly higher than that in the control group. IHC results also confirmed that the expression of COL10A1 in the experimental group was significantly higher than that in the control group at 3 and 6 months after surgery(P＜0.05).</p><p><strong>Conclusions: </strong>The combination of L-PRF and DBBM can significantly increase the osteogenic volume, improve the osteogenic quality, and accelerate the healing speed in the bone graft area during lateral window maxillary sinus floor elevation and bone grafting surgery. It optimizes the bone repair process by promoting the expression of COL10A1.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"60-65"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Investigation of postoperative xerostomia and contributory factors in patients with oral cancer].","authors":"Xingtong Guo, Lili Hou","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the current status of postoperative xerostomia in patients with oral cancer and the contributory factors.</p><p><strong>Methods: </strong>A total of 140 patients undergoing oral cancer surgery in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from March 2022 to November 2022 were selected as the study objects. The Numberical Rating Scale(NRS) and Unstimulated Saliva Flow Rate(USFR) were used to assess the degree of oral dryness. Thirst level was assessed using the Thirst Distress Scale(TDS). The quality of life and psychological status of patients were evaluated by Quality of Life Questionnaire-the Head and Neck Cancer Module (QLQ-H N35) and Self-rating Anxiety Scale. The influence factors of NRS and USFR were analyzed by univariate and multifactorial regression.</p><p><strong>Results: </strong>The results of multifactorial analysis showed that in terms of dry mouth severity, patients more than 60 years old had higher NRS scores than those less than 60 years old(β=-0.133, P＜0.001). Bilateral removal of submandibular gland had higher NRS score than those with unresected/unilateral submandibular gland removal(β=-0.139, P=0.002). Patients with tracheotomy had higher NRS score than those without tracheotomy(β=-0.104, P=0.007). The higher NRS scores for postoperative abstinence from drinking for five days or more(β=-0.099，P=0.002), higher NRS scores for open-mouth breathing(β=-0.103，P=0.006). Higher postoperative QLQ-H N35(β=0.007，P＜0.001) and TDS(β=0.112，P＜0.001) scores were associated with more severe oral dryness. USFR was lower in females compared to males(β=0.009, P=0.045), patients with a history of alcohol consumption(β=-0.018, P=0.002), patients treated with preoperative chemotherapy(β=0.015, P=0.006), patients with more than 11h of preoperative abstinence from drinking(β=0.02, P=0.001), and tracheotomized patients(β=-0.011, P=0.048). Patients with lower preoperative USFR had lower postoperative USFR(β=0.105, P＜0.001), patients with higher TDS scores had a lower USFR(β=-0.006, P＜0.001).</p><p><strong>Conclusions: </strong>Gender, age, submandibular gland removal, parotid duct ligation, tracheotomy, length of postoperative abstinence from drinking, open-mouth breathing, postoperative quality of life, and thirst affected patients' oral dryness and salivation. Healthcare professionals should recognize early and provide a basis for developing care measures to reduce oral dryness.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"35 1","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The clinical effect of tunnel technique combined with connective tissue grafting in the treatment of gingival recession with non-carious cervical lesion].","authors":"Fengqin Guo, Wei Zhang, Hong Zhu, Xianfang Zha, Xiaojing Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the clinical efficacy of tunnel technique combined with connective tissue grafting in the treatment of gingival recession with non-carious cervical lesion(NCCL).</p><p><strong>Methods: </strong>Fourteen patients with 26 gingival receding sites who were admitted to Hefei Stomatological Hospital from January 2021 to August 2022 due to gingival receding and sensitivity to cold and heat were selected as the research objects. All patients were treated with tunnel technology combined with connective tissue grafting. Clinical indexes such as gingival receding (GR), probing depth (PD), clinical attachment loss(CAL), keratinized gingival width (KTW) and tooth defect depth were measured before surgery, 3 months after surgery and 6 months after surgery, respectively, to evaluate the clinical efficacy.</p><p><strong>Results: </strong>At 3 and 6 months after surgery, GR and CAL were significantly decreased(P＜0.05), and KTW was significantly increased(P＜0.05). Three months after operation, the complete root coverage rate was 77.00%, and the average root coverage rate was 94.23%. At 6 months after operation, the complete root coverage rate was 73.00%, and the average root coverage rate was 93.27%.</p><p><strong>Conclusions: </strong>Tunnel technique combined with connective tissue grafting can be used for the treatment of MillerⅠ and Miller Ⅱ gingival receding with NCCL, and the clinical and aesthetic results are significant and stable.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"34 6","pages":"656-659"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of the efficacy of bone-level implantation combined with orthodontics in patients with dentition defect].","authors":"Yanhua Lei, Haixia Zheng","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of bone-level implantation combined with orthodontics on periodontal health and implant stability in patients with dentition defect.</p><p><strong>Methods: </strong>A total of 92 patients(92 teeth) with dentition defect admitted to the hospital from January 2020 to January 2023 were selected and divided into 2 groups by random number table method, with 46 cases in each group. All patients in the two groups were treated with bone-level implantation, and the experimental group was treated combined with orthodontics before implantation. The implant success rate 6 months post-surgery, along with the periodontal status before and 6 months after implantation [sulcus bleeding index (SBI), probing depth(PD), plaque index (PLI)], chewing function, bone resorption, implant stability quotient and incidence of complications (occlusal elevation, non-occlusal contact, food impaction and occlusal pain) were compared.</p><p><strong>Results: </strong>The implantation success rate of the experimental group was significantly higher than that of the control group, SBI, PD and PLI after 6 months of implantation were significantly lower than those of the control group, and the surface myoelectric activity of temporal muscle, bilateral masseter muscle and implant stability coefficient at maximum occlusion were significantly higher than those of the control group(P＜0.05). There was no significant difference in bone absorption between the two groups(P＞0.05), and the complication rate of the experimental group was significantly lower than that of the control group(P＜0.05).</p><p><strong>Conclusions: </strong>Bone-level implantation combined with orthodontics helps improve periodontal health and enhances implant stability in patients with dentition defect.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"34 6","pages":"622-625"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147327002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}